「20」の検索結果

Normalizes ChIP-seq data using exogenous spike-in (ChIP-Rx with Drosophila chromatin per Orlando 2014 / Egan 2016; E. coli carryover for CUT&RUN/CUT&Tag). Distinguishes RRPM from Rx-Input scaling, integrates with DiffBind / DESeq2 / edgeR / csaw via sizeFactors and DiffBind library-size vectors, applies the Patel et al 2024 *Nat Biotechnol* failure-mode framework, and validates that normalization is applied at the read level (not peak counts). Use when global signal shifts are expected (HDACi, BETi, EZH2i, dosage, target knockdown), when ChIPseqSpikeInFree detects post-hoc shifts, or when validating internal-control regions before publication.

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Designs Bayesian clinical trials including Phase I dose-finding (BOIN, CRM, EWOC, mTPI-2), meta-analytic-predictive (MAP) priors with robust mixtures for external data borrowing, EXNEX for basket trials, hierarchical models for safety AE (Berry-Berry), Bayesian platform trials (I-SPY 2, GBM AGILE, REMAP-CAP), and posterior probability stopping rules. Covers FDA Bayesian Devices Guidance (2010), FDA Bayesian Methodology in Drugs Draft (January 2026), BOIN Fit-for-Purpose qualification (December 2021), and Project Optimus dose-optimisation. Use when designing dose-finding studies, platform trials, or sensitivity analyses with informative priors.

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Prepares statistical reports for clinical trials following CONSORT 2025, SPIRIT 2025, ICH E9(R1) estimands, and FDA 2023 covariate adjustment guidance. Covers Table 1 generation, analysis populations (ITT/FAS/PP/Safety), the 5 ICH E9(R1) intercurrent-event strategies, MMRM under MAR (mmrm), reference-based MI (rbmi J2R/CR/CIR), Permutt tipping-point sensitivity, and Rubin's-rules vs frequentist variance debate. Use when preparing regulatory submissions, defining estimands, or implementing missing-data sensitivity analyses.

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Port MATLAB Data Acquisition Toolbox code from the discouraged (legacy) session-based interface (daq.createSession, addAnalogInputChannel, startBackground, DataAvailable listeners, queueOutputData, wait) to the recommended DataAcquisition interface (daq("ni"), addinput, start, ScansAvailableFcn, write, preload). Use when migrating legacy DAQ scripts, converting session-API calls, working with DataAcquisition objects, writing multi-feature DAQ scripts that combine triggers, callbacks, continuous acquisition, or analog output. Also use when a user says their DAQ script "used to work" or "errors on R20XX", since modernizing legacy session-API code is a frequent fix for those failures. Trigger keywords: daq, DAQ, NI, session interface, addtrigger, addclock, ScansAvailableFcn, ScansRequiredFcn, daq.createSession, addAnalogInputChannel, startBackground, queueOutputData, DataAvailable, evt.Data, evt.TimeStamps, wait(d), preload, discouraged, legacy, modernize, R2020a.

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Use when doing any Autodesk Maya task through Python or a bridge, headless or live: maya.cmds or OpenMaya 2.0 scripts, mayapy or maya.standalone batch jobs, a commandPort or MCP connection into a running Maya, "Maya 2027", validating or exporting scenes, or a maya.cmds script that fails after the 2025 to 2027 changes (PySide6, OpenPBR, renamed math nodes, removed flags). Also when a Maya model, rig, shot or render must be judged like a professional before it is called done, or a brief must be routed to the right Maya specialist.

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California Consumer Privacy Act (CCPA) and California Privacy Rights Act (CPRA) compliance advisor — business threshold analysis, consumer rights fulfillment (access, delete, correct, opt-out of sale/sharing, limit SPI, ADMT opt-out), privacy notice drafting, service provider vs. contractor vs. third-party classification, sensitive personal information (SPI) handling, data minimization, opt-out mechanisms (including GPC), cybersecurity audits and risk assessments (live since Jan 1, 2026), ADMT obligations (effective 2026, deadline Jan 1, 2027), CPPA enforcement (Disney $2.75M, PlayOn $1.1M, Ford $375K), penalty exposure, GDPR comparison, and gap assessments for businesses operating in or targeting California residents.

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Expert ISO 27701 Privacy Information Management System (PIMS) compliance advisor. Use this skill whenever a user asks about ISO/IEC 27701:2025, ISO/IEC 27701:2019, privacy information management, PIMS certification, PII controller or processor obligations, privacy risk assessment, Statement of Applicability for privacy, privacy by design, data subject rights, DPIA, records of processing activities, transitioning from ISO 27701:2019, GDPR alignment with ISO 27701, or any privacy management system topic. Also trigger for questions about Annex A.1 (controller controls), A.2 (processor controls), A.3 (shared security controls), or implementing a standalone PIMS without ISO 27001. When in doubt, use this skill — it covers the full ISO 27701 lifecycle from gap assessment through certification.

日本語の概要は準備中です。原文の説明を表示しています。

Expert Vietnam Personal Data Protection Law (PDPL) compliance advisor for Law No. 91/2025/QH15 and implementing Decree 356/2025/ND-CP (effective January 1, 2026). Use this skill for gap analysis against the Vietnam PDPL, data subject rights fulfilment workflows, cross-border data transfer impact assessments, privacy notices and internal policies, breach notification procedures, sector-specific obligations (finance, AI, cloud, blockchain), and DPO qualification reviews. Trigger whenever a user mentions Vietnam data privacy, VN-PDPL, Nghị định 356, Vietnamese personal data, or cross-border transfers involving Vietnamese citizens' data.

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EU NIS2 Directive (Directive (EU) 2022/2555) compliance advisor for essential and important entities: entity classification, Art. 21 risk management measures, Art. 23 incident reporting timelines (24h/72h/1 month), Art. 20 governance obligations, supply chain security (Art. 21(2)(d); coordinated risk assessments Art. 22), gap assessments, policy drafting, ISO 27001 alignment, and penalty exposure analysis. Also covers Commission Implementing Regulation (EU) 2024/2690, the technical/methodological sub-requirements for Art. 21(2) and the significant-incident thresholds binding on DNS/cloud/data-centre/MSP/MSSP/trust-service and other digital entities. Use for NIS2 readiness, transposition questions, ENISA technical implementation guidance, significant-incident thresholds, supervisory differences between essential and important entities, and cross-border coordination.

日本語の概要は準備中です。原文の説明を表示しています。

Expert Vietnam Personal Data Protection Law (PDPL) compliance advisor for Law No. 91/2025/QH15 and implementing Decree 356/2025/ND-CP (effective January 1, 2026). Use this skill for gap analysis against the Vietnam PDPL, data subject rights fulfilment workflows, cross-border data transfer impact assessments, privacy notices and internal policies, breach notification procedures, sector-specific obligations (finance, AI, cloud, blockchain), and DPO qualification reviews. Trigger whenever a user mentions Vietnam data privacy, VN-PDPL, Nghị định 356, Vietnamese personal data, or cross-border transfers involving Vietnamese citizens' data.

日本語の概要は準備中です。原文の説明を表示しています。

Guide for (a) auditing an existing whistleblower system or (b) drafting a compliant reporting policy from a provided template. Covers EU Directive 2019/1937, the amended Sapin II law (Waserman 2022), Decree 2022-1284, CNIL guidelines, public sector requirements, and duty of vigilance.

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Verification-first methodology for the UNMIK Regulation 64 Panels of the Kosovo district courts (2000–2008). Citations are verified against UNMIK/EULEX archives and legal-tools.org. Keeps the Reg. 64 Panels distinct from the Kosovo Specialist Chambers, and clarifies that Reg. 2000/64 permitted (did not impose) internationally-majority panels. Research aid, not legal advice. Part of the open-source "Skills for International Justice" library — methodology: github.com/jeannesulzer/international-criminal-tribunals-skills

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GDPR Transfer Impact Assessment for Chapter V transfers under the EDPB Recommendations 01/2020 six-step methodology, the CNIL TIA Guide (January 2025), and EDPB essential guarantees. Handles transfer qualification, Art. 45 adequacy fast-tracks, Art. 46 full assessments with country profiles for 12 jurisdictions, and balanced Art. 49 derogation analysis. Outputs a Markdown report, a .docx formal TIA, and a JSON delta for RoPA interchange.

日本語の概要は準備中です。原文の説明を表示しています。

Verification-first methodology for the Jurisdicción Especial para la Paz (JEP), Colombia's transitional justice court under the 2016 Acuerdo Final with FARC-EP. Citations are verified against jep.gov.co before use. Covers the 11 macrocasos (from Caso 01 secuestro through Caso 11 violencia sexual, including Caso 03 falsos positivos), the three sanction tiers (propias, alternativas, ordinarias), TOAR, and the SIVJRNR sister bodies (CEV, UBPD). Guards the key structural distinctions (Sala de Reconocimiento vs Tribunal para la Paz; comparecientes FARC-EP vs Fuerza Pública vs terceros civiles; Acto Legislativo 01/2017 vs Ley Estatutaria 1957/2019). Research aid, not legal advice.

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Sanctions and export control analysis tool for Claude Desktop. Real-time individual screening across 30+ official lists (UN, EU, OFAC, OFSI, French DGT...), sectoral analysis, dual-use goods (EU Reg. 2021/821), US/China extraterritorial regimes (EAR, ITAR, FDPR, ECL), USD/SWIFT risk and jurisdictional mapping across 30+ countries. All results sourced and verified in real time — no memory-based answers. Responds in French, English, German, Spanish, Russian and Chinese. Updated 19 May 2026 (EU 20th package, UK SEUC, Cuba EO). Indicative guidance only — not legal advice.

日本語の概要は準備中です。原文の説明を表示しています。

EU NIS2 Directive (Directive (EU) 2022/2555) compliance advisor for essential and important entities: entity classification, Art. 21 risk management measures, Art. 23 incident reporting timelines (24h/72h/1 month), Art. 20 governance obligations, supply chain security (Art. 21(2)(d); coordinated risk assessments Art. 22), gap assessments, policy drafting, ISO 27001 alignment, and penalty exposure analysis. Also covers Commission Implementing Regulation (EU) 2024/2690, the technical/methodological sub-requirements for Art. 21(2) and the significant-incident thresholds binding on DNS/cloud/data-centre/MSP/MSSP/trust-service and other digital entities. Use for NIS2 readiness, transposition questions, ENISA technical implementation guidance, significant-incident thresholds, supervisory differences between essential and important entities, and cross-border coordination.

日本語の概要は準備中です。原文の説明を表示しています。

Expert ISO 27701 Privacy Information Management System (PIMS) compliance advisor. Use this skill whenever a user asks about ISO/IEC 27701:2025, ISO/IEC 27701:2019, privacy information management, PIMS certification, PII controller or processor obligations, privacy risk assessment, Statement of Applicability for privacy, privacy by design, data subject rights, DPIA, records of processing activities, transitioning from ISO 27701:2019, GDPR alignment with ISO 27701, or any privacy management system topic. Also trigger for questions about Annex A.1 (controller controls), A.2 (processor controls), A.3 (shared security controls), or implementing a standalone PIMS without ISO 27001. When in doubt, use this skill — it covers the full ISO 27701 lifecycle from gap assessment through certification.

日本語の概要は準備中です。原文の説明を表示しています。

Index analytiques sourcés du corpus réglementaire et doctrinal sur la gouvernance des émetteurs cotés français (rapports AMF et HCGE 2020-2025, guide d'application HCGE, rapport sénatorial Rietmann/Gay, Code AFEP-MEDEF, sources légales et européennes). À utiliser pour : (1) retrouver une position, une statistique ou une citation exacte avec sa source et sa page ; (2) analyser l'évolution longitudinale des positions AMF/HCGE/ESMA sur un thème ; (3) appliquer la grille d'analyse en 13 blocs (A-M) à un émetteur. Déclencher pour toute question sur la gouvernance d'une société cotée française : conseil d'administration, indépendance des administrateurs, comités, rémunération des dirigeants, say on pay, say on climate, assemblée générale, droits des actionnaires, plans de succession, mixité, RSE/CSRD, comply-or-explain, name and shame AMF, soft law AFEP-MEDEF, recommandations AMF, positions HCGE.

日本語の概要は準備中です。原文の説明を表示しています。

California Consumer Privacy Act (CCPA) and California Privacy Rights Act (CPRA) compliance advisor — business threshold analysis, consumer rights fulfillment (access, delete, correct, opt-out of sale/sharing, limit SPI, ADMT opt-out), privacy notice drafting, service provider vs. contractor vs. third-party classification, sensitive personal information (SPI) handling, data minimization, opt-out mechanisms (including GPC), cybersecurity audits and risk assessments (live since Jan 1, 2026), ADMT obligations (effective 2026, deadline Jan 1, 2027), CPPA enforcement (Disney $2.75M, PlayOn $1.1M, Ford $375K), penalty exposure, GDPR comparison, and gap assessments for businesses operating in or targeting California residents.

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Offers functions for plotting split (or implicit) networks (unrooted, undirected) and explicit networks (rooted, directed) with reticulations extending. 'ggtree' and using functions from 'ape' and 'phangorn'. It extends the 'ggtree' package [@Yu2017] to allow the visualization of phylogenetic networks using the 'ggplot2' syntax. It offers an alternative to the plot functions already available in 'ape' Paradis and Schliep (2019) <doi:10.1093/bioinformatics/bty633> and 'phangorn' Schliep (2011) <d

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OWASP Top 10 audit checklists for Web Applications (2021), APIs (2023), and Mobile (2024). Use when performing any security review, PR review, or codebase audit touching web, mobile, or API code.

日本語の概要は準備中です。原文の説明を表示しています。

Query 2021-2025 CUMCM school awards and 2026 forecasts, or assess a student's preparation distance from provincial and national awards using school history and prior modeling experience.

日本語の概要は準備中です。原文の説明を表示しています。

Use when crossing a Windows security boundary or escaping a sandbox — kernel/user crossing (win32k/dxgkrnl UAF CVE-2025-24983), BYOVD kernel R/W, UAC/COM elevation, AppContainer/LPAC & Chromium-Mojo sandbox escape (CVE-2025-2783), PPL bypass, RPC/ALPC & named-pipe impersonation

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Use when attacking a Windows Active Directory domain — Kerberos roasting/delegation, coercion + NTLM/Kerberos relay (CVE-2025-33073), ADCS ESC1-16 (EKUwu), ticket forgery & DCSync, dMSA BadSuccessor (CVE-2025-53779), BloodHound attack-path enumeration, domain dominance

日本語の概要は準備中です。原文の説明を表示しています。