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Cell segmentation from multiplexed tissue images. Covers deep learning (Cellpose, Mesmer) and classical approaches for nuclear and whole-cell segmentation. Use when extracting single-cell data from IMC or MIBI images after preprocessing.

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Perform differential expression analysis using DESeq2 in R/Bioconductor. Use for analyzing RNA-seq count data, creating DESeqDataSet objects, running the DESeq workflow, and extracting results with log fold change shrinkage. Use when performing DE analysis with DESeq2.

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Screen S&P 500 stocks for Mark Minervini's Volatility Contraction Pattern (VCP) and detect historical VCPs in a single ticker's price path. Identifies Stage 2 uptrend stocks forming tight bases with contracting volatility near breakout pivot points; in historical single-ticker mode walks a multi-year history and emits every VCP that formed with forward-outcome stats (breakout / stop-hit / timeout). Use when user requests VCP screening, Minervini-style setups, tight base patterns, volatility contraction breakout candidates, Stage 2 momentum stock scanning, or historical VCP pattern study on a specific ticker (e.g. FIX, TSLA).

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Model component behaviour as explicit states, events, and transitions. Use when a component has many interacting states that must be exhaustive. For the feel and feedback of a single interaction, use `micro-interaction-spec`.

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Build a complete web scraping Actor with Crawlee and deploy to Apify. Use when you need end-to-end web scraping on Apify: defining an input schema, building a router-based Crawlee crawler, extracting structured data, storing results in a dataset, testing locally, and deploying the Actor to the platform. Trigger with "apify scrape website", "build apify actor", "crawlee scraper", "apify main workflow".

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Browser automation CLI for AI agents. Use when the user needs to interact with websites, including navigating pages, filling forms, clicking buttons, taking screenshots, extracting data, testing web apps, or automating any browser task. Triggers include requests to "open a website", "fill out a form", "click a button", "take a screenshot", "scrape data from a page", "test this web app", "login to a site", "automate browser actions", or any task requiring programmatic web interaction.

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Comprehensive PDF manipulation toolkit for extracting text and tables, creating new PDFs, merging/splitting documents, and handling forms. When Claude needs to fill in a PDF form or programmatically process, generate, or analyze PDF documents at scale.

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Use this skill whenever the user wants to create, read, edit, or manipulate Word documents (.docx files) or Word templates (.dotx files). Triggers include: any mention of 'Word doc', 'word document', '.docx', '.dotx', or requests to produce professional documents with formatting like tables of contents, headings, page numbers, or letterheads. Also use when extracting or reorganizing content from .docx or .dotx files, inserting or replacing images in documents, performing find-and-replace in Word files, working with tracked changes or comments, or converting content into a polished Word document. If the user asks for a 'report', 'memo', 'letter', 'template', or similar deliverable as a Word or .docx file, use this skill. Do NOT use for PDFs, spreadsheets, Google Docs, or general coding tasks unrelated to document generation.

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Use this skill any time a .pptx or .potx file is involved in any way — as input, output, or both. This includes: creating slide decks, pitch decks, or presentations; reading, parsing, or extracting text from any .pptx or .potx file (even if the extracted content will be used elsewhere, like in an email or summary); editing, modifying, or updating existing presentations; combining or splitting slide files; working with templates (.potx), layouts, speaker notes, or comments. Trigger whenever the user mentions "deck," "slides," "presentation," or references a .pptx or .potx filename, regardless of what they plan to do with the content afterward. If a .pptx or .potx file needs to be opened, created, or touched, use this skill.

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Talk to customers without leading them using Mom Test rules: discuss their life not your idea, ask about specifics in the past, and talk less. Use when the user mentions "customer interviews", "validate my idea", "users say they want it but dont buy", "leading questions", "The Mom Test", "customer feedback bias", or "interview script". Also trigger when preparing user-research questions, interpreting ambiguous feedback, or designing customer-discovery that avoids false positives. Covers commitment and advancement, avoiding compliments, and extracting signal from noise. For product-market fit, see jobs-to-be-done. For rapid prototype testing, see design-sprint.

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Detect keyword cannibalization across blog posts by extracting primary keywords from titles and headings, clustering semantically similar targets, and flagging posts competing for the same search intent. Supports local-only mode (grep-based) and DataForSEO API mode (Page Intersection endpoint at ~$0.01/call). Outputs severity-scored report with merge or differentiate recommendations. Use when user says "cannibalization", "keyword overlap", "competing pages", "duplicate keywords", "cannibalize".

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Comprehensive PDF manipulation toolkit for extracting text and tables, creating new PDFs, merging/splitting documents, and handling forms. When Claude needs to fill in a PDF form or programmatically process, generate, or analyze PDF documents at scale.

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Process and generate multimedia content using Google Gemini API. Capabilities include analyze audio files (transcription with timestamps, summarization, speech understanding, music/sound analysis up to 9.5 hours), understand images (captioning, object detection, OCR, visual Q&A, segmentation), process videos (scene detection, Q&A, temporal analysis, YouTube URLs, up to 6 hours), extract from documents (PDF tables, forms, charts, diagrams, multi-page), generate images (text-to-image, editing, composition, refinement). Use when working with audio/video files, analyzing images or screenshots, processing PDF documents, extracting structured data from media, creating images from text prompts, or implementing multimodal AI features. Supports multiple models (Gemini 2.5/2.0) with context windows up to 2M tokens.

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Process multimedia files with FFmpeg (video/audio encoding, conversion, streaming, filtering, hardware acceleration) and ImageMagick (image manipulation, format conversion, batch processing, effects, composition). Use when converting media formats, encoding videos with specific codecs (H.264, H.265, VP9), resizing/cropping images, extracting audio from video, applying filters and effects, optimizing file sizes, creating streaming manifests (HLS/DASH), generating thumbnails, batch processing images, creating composite images, or implementing media processing pipelines. Supports 100+ formats, hardware acceleration (NVENC, QSV), and complex filtergraphs.

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Comprehensive PDF manipulation toolkit for extracting text and tables, creating new PDFs, merging/splitting documents, and handling forms. When Claude needs to fill in a PDF form or programmatically process, generate, or analyze PDF documents at scale.

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Uninstall or hard-clean OpenClaw Companion, Windows node, native Gateway/MXC, WSL Gateway, and managed llama.cpp/Local AI state for a clean retest. Choose the existing dev CLI uninstall or the reviewed hard-clean procedure, inventory exact targets, and obtain destructive confirmation before acting.

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Conducts and responds to code review — reviewing a change for correctness, design, and risk, and evaluating review feedback received on your own work. Use this before merging, when asked to review a diff or pull request, when review feedback has arrived and needs acting on, or when feedback seems wrong and needs a reasoned response rather than compliance.

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Answers a business question with data without fooling yourself — framing the question so an answer would change something, choosing the right comparison, checking the data before trusting it, recognizing the traps that produce confident wrong answers (aggregation reversals, survivorship, regression to the mean, multiple comparisons), and reporting uncertainty honestly. Use this to run an analysis, review one before acting on it, or work out why two people looking at the same data reached opposite conclusions.

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Builds the help center, in-product guidance, and knowledge base that let customers resolve problems without contacting anyone — content, findability, maintenance, and deflection measurement. Use this to build or fix a help center, reduce support volume, write documentation for customers, improve findability, or decide what deserves a help article versus a product fix.

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Toolkit for interacting with and testing local web applications using Playwright. Supports verifying frontend functionality, debugging UI behavior, capturing browser screenshots, and viewing browser logs.

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Summarize YouTube videos by extracting transcripts and generating structured notes. Use when the user wants to summarize a YouTube video, extract key points from a talk, create study notes from a lecture, or get timestamps for important moments. Supports multiple URL formats and languages.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill whenever the user wants to create, read, edit, or manipulate Word documents (.docx files). Triggers include: any mention of "Word doc", "word document", ".docx", or requests to produce professional documents with formatting like tables of contents, headings, page numbers, or letterheads. Also use when extracting or reorganizing content from .docx files, inserting or replacing images in documents, performing find-and-replace in Word files, working with tracked changes or comments, or converting content into a polished Word document. If the user asks for a "report", "memo", "letter", "template", or similar deliverable as a Word or .docx file, use this skill. Do NOT use for PDFs, spreadsheets, Google Docs, or general coding tasks unrelated to document generation.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill any time a .pptx file is involved in any way — as input, output, or both. This includes: creating slide decks, pitch decks, or presentations; reading, parsing, or extracting text from any .pptx file (even if the extracted content will be used elsewhere, like in an email or summary); editing, modifying, or updating existing presentations; combining or splitting slide files; working with templates, layouts, speaker notes, or comments. Trigger whenever the user mentions "deck," "slides," "presentation," or references a .pptx filename, regardless of what they plan to do with the content afterward. If a .pptx file needs to be opened, created, or touched, use this skill.

日本語の概要は準備中です。原文の説明を表示しています。

Comprehensive PDF manipulation toolkit for extracting text and tables, creating new PDFs, merging/splitting documents, and handling forms. When Claude needs to fill in a PDF form or programmatically process, generate, or analyze PDF documents at scale.

日本語の概要は準備中です。原文の説明を表示しています。