「diagnostic」の検索結果

Designs discovery, modeling, and validation workflows for prognostic biomarkers in biomedical and clinical research. Always use this skill when the user needs a prognostic biomarker study blueprint rather than a diagnostic test protocol, predictive biomarker design, treatment recommendation, or a completed manuscript. Focus on endpoint family, follow-up horizon, time scale, candidate marker strategy, model-building logic, risk stratification framework, and internal/external validation requirements. Do not invent cohort size, event rate, assay readiness, literature support, or validation access.

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Generates complete phenotype-scoring bioinformatics research designs for any disease context and any user-defined phenotype, pathway, process, signature, or molecular program. Use when a study centers on gene-set or feature-set definition, intersection with DEGs or candidate features, phenotype scoring, feature selection, diagnostic or stratification assessment, immune or cellular-resolution interpretation, network analysis, and optional orthogonal validation. Covers five study patterns (signature discovery, phenotype scoring, feature selection, immune/cellular interpretation, multi-layer validation) and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.

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Designs studies for predicting treatment response or resistance in biomedical and clinical research. Always use this skill when the user needs a treatment-response or resistance prediction study blueprint rather than a prognostic biomarker protocol, diagnostic test design, causal treatment-effect estimation, or a completed manuscript. Focus on responder definition, treatment context, baseline comparability, feature integration strategy, model development logic, validation architecture, and interpretation boundaries. Do not invent response rates, cohort size, assay readiness, regimen uniformity, literature support, or validation access.

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Generates complete conventional oncology bulk-transcriptome biomarker and hub-gene research designs from a user-provided cancer type and study direction. Always use this skill whenever a user wants to design, plan, or build a tumor bioinformatics study centered on differential expression, prognostic filtering or risk modeling, PPI-based hub-gene prioritization, diagnostic/prognostic evaluation, clinical association, immune infiltration context, methylation context, and optional tissue or cell validation. Covers five study patterns (signature-first prognostic workflow, hub-gene-first biomarker workflow, hybrid signature-to-hub workflow, immune-context biomarker workflow, translational validation workflow) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path...

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Generates complete dual-disease shared-transcriptome biomarker and hub-gene research designs from a user-provided disease pair and shared-biology direction. Always use this skill whenever a user wants to design, plan, or build a non-oncology two-disease transcriptome study centered on per-disease differential expression, shared-signal intersection or concordance, PPI-based hub-gene prioritization, diagnostic evaluation across both diseases, immune infiltration context, pathway interpretation, and optional orthogonal validation. Covers five study patterns (shared-DEG-first workflow, hub-gene-first shared-biomarker workflow, hybrid shared-biomarker compression workflow, immune-context shared-biomarker workflow, orthogonal validation workflow) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path...

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Extracts concrete unmet clinical needs from guidelines, reviews, real-world studies, and clinical-practice evidence. Use this skill when a user wants to turn broad medical research value into specific clinical pain points such as weak early detection, poor risk stratification, treatment-response heterogeneity, monitoring gaps, diagnostic delay, undertreatment, overtreatment, or implementation failure. Always ground unmet-need claims in retrieved evidence and distinguish true care gaps from generic statements of importance.

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Evidence-based medical knowledge and research mentor grounded in the Bian Que tradition. Covers clinical reasoning, diagnostic thinking (望闻问切), pharmacology, pathology, differential diagnosis, medical literature appraisal, and the philosophy of early intervention. Trigger whenever users ask about medicine, clinical science, drugs, disease mechanisms, diagnosis, lab interpretation, treatment comparison, or health sciences. Even without explicit research framing, trigger on any topic touching disease, therapeutics, or clinical decision-making. Part of the AIPOCH Medical Research Skill Hub.

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Build medical AI agents for clinical decision support, medical record summarization, diagnostic assistance, and healthcare workflow automation.

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Diagnostic guide for RL-based post-training of language models (GRPO, PPO, REINFORCE, DPO). Use proactively when debugging a training pipeline that shows no improvement, loss anomalies, reward stagnation, NaN gradients, or other unexpected behavior during reinforcement learning fine-tuning. Work through all pipeline stages — reward, advantages, log-probs, loss, generation/decoding — before concluding the diagnosis is complete; stopping after one or two fixes is a common failure mode. Covers log-probability math, advantage estimation, numerical stability, reward processing, and generation/decoding pipeline issues.

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You are an error tracking and observability expert specializing in implementing comprehensive error monitoring solutions. Set up error tracking systems, configure alerts, implement structured logging,

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You are an expert error analysis specialist with deep expertise in debugging distributed systems, analyzing production incidents, and implementing comprehensive observability solutions.

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You are a debugging expert specializing in setting up comprehensive debugging environments, distributed tracing, and diagnostic tools. Configure debugging workflows, implement tracing solutions, and establish troubleshooting practices for development and production environments.

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Diagnose why Claude Code is (or isn't) prompting for permission. By default reads only repo-local layers (CLI project, CLI project-local, VSCode workspace). Host-global layers (CLI user `~/.claude/`, VSCode user settings) are read ONLY when the user explicitly confirms — those files may contain unrelated paths or secrets. Use when user says "why is it asking me to approve?", "permission check", "why am I getting prompts?", "bypass isn't working", "check my permissions". Read-only diagnostic.

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Genre anatomy from John Truby's The Anatomy of Genres (类型解剖 / 类型节拍 / 混合类型 / 超越类型) — genres as beat systems with a life philosophy underneath; three rules (hit every beat of your genre, mix three or four genres, transcend the primary genre), the ladder and families of twelve genres (Horror 恐怖, Action 动作, Myth 神话, Memoir and Coming-of-Age 回忆录与成长, Science Fiction 科幻, Crime 犯罪, Comedy 喜剧, Western 西部, Gangster 黑帮, Fantasy 奇幻, Detective and Thriller 侦探与惊悚, Love 爱情), each with its hero/opponent/world/plot-shape template, beat list, hard rules with failure conditions, subgenres and transcendent paths, plus a genre-mixing worksheet and a diagnostic. Kept beside sw-truby-anatomy and the Field/Snyder page maps. Use when choosing or confirming a script's genre, when a genre story feels generic or misses the beats its audience expects, when mixing genres, when a horror lacks pressure, an action lacks plot, a love story lacks opposition or a detective story lacks reveals.

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dontbesilent AI 写作特征识别。扫描文案中的 AI 生成痕迹，输出检测报告。默认只诊断不改。 触发方式：/dbs-ai-check、/AI检测、「帮我看看有没有 AI 味」「检测一下 AI 特征」 AI writing fingerprint detection. Scans copy for AI-generated patterns and outputs a diagnostic report. Diagnosis only by default. Trigger: /dbs-ai-check, "check for AI writing", "does this sound like AI"

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Lookup documented AKS fixes only when the prompt includes an exact catalog signature and all of its qualifiers: VMCannotFitEphemeralOSDisk; NodePoolMcVersionIncompatible; 'NodeImageVersion is not accepted'; AKS SkuNotAvailable with size, location, and zone; ZonalAllocationFailed with insufficient zone capacity; OverconstrainedAllocationRequest with listed constraints; nested AKS vmssCSE/CSE VMExtensionError_OutboundConnFail, VMExtensionError_K8SAPIServerConnFail, or VMExtensionError_K8SAPIServerDNSLookupFail; or AllocationFailed with the full cataloged internal-error or insufficient-regional-capacity message. Never use for quota errors, code-only or bare wrappers, generic symptoms, incomplete signatures, or failures outside AKS; use aks-troubleshooting or azure-diagnostics.

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Debug live Azure Kubernetes Service (AKS) incidents with a read-only, evidence-first investigation. WHEN: pod crashes or Pending, CrashLoopBackOff, OOMKilled, ImagePullBackOff, node NotReady, DNS or ingress failure, connectivity timeout, network policy, SNAT exhaustion, node-pool scaling blocked by QuotaExceeded or InsufficientVCPUQuota, upgrade stuck, spot or zone disruption, a bare VMExtensionProvisioningError or AllocationFailed wrapper, an uncataloged capacity symptom, or 'investigate my AKS cluster'. DO NOT USE FOR: packet capture (use aks-network-capture); GPU or model-serving issues (use aks-gpu-inference); cluster creation or provisioning (use azure-kubernetes); cost (use cost-analysis from the optional azure-cost plugin); pod rightsizing (use azure-kubernetes); a fully qualified documented AKS signature with every required nested qualifier (use aks-known-issues); standalone failures on non-AKS Azure resources (use azure-diagnostics). Unqualified errors and open-ended incidents stay here only for AKS.

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Collects bounded packet captures from AKS nodes and Azure network configuration for wire-level evidence. WHEN: "capture packets on an AKS node", "take a pcap", "run tcpdump on AKS", "prove where packets drop". Use for explicit packet-capture intent after read-only diagnostics, not general AKS connectivity or ingress troubleshooting.

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Debug Azure production issues on Azure using AppLens, Azure Monitor, resource health, and safe triage. WHEN: debug production issues, troubleshoot app service, app service high CPU, app service deployment failure, troubleshoot container apps, container app 503 or target port mismatch, troubleshoot functions, function telemetry missing or stopped after a config/connection-string change, troubleshoot AKS, VM RDP, Linux SSH, VM black screen, can't connect to VM, reset VM password, NSG or firewall blocking, kubectl cannot connect, kube-system/CoreDNS failures, pod pending, crashloop, node not ready, upgrade failures, analyze logs, KQL, insights, image pull failures, cold start issues, health probe failures, resource health, root cause of errors, troubleshoot event hubs, troubleshoot service bus, messaging SDK error, AMQP connection failure, message lock lost, lock renewal during long-running processing, service bus dead letter.

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Comprehensive diagnostic analysis of time series data. Use when users provide CSV time series data and want to understand its characteristics before forecasting - stationarity, seasonality, trend, forecastability, and transform recommendations.

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This skill should be used when picking or diagnosing a training move (SFT, LoRA, DPO/KTO/ORPO, RFT, GRPO/PPO/RLOO, RLHF), or when the user mentions fine-tuning, post-training, training recipe, reward design, or weight updates. Decision tree by reward shape, smoke-run gate, three failure diagnostics, five false-progress patterns. Provider recipes and I/O contract in references/.

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Comprehensive diagnostic analysis of time series data. Use when users provide CSV time series data and want to understand its characteristics before forecasting - stationarity, seasonality, trend, forecastability, and transform recommendations.

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Interactive quiz tutor for Obsidian StudyVault learning. Use when the user wants to: (1) Take a diagnostic assessment of their knowledge, (2) Study or review specific sections/topics, (3) Drill weak areas identified in previous sessions, (4) Check their learning progress or dashboard, or says things like "quiz me", "test me", "let's study", "/tutor", "학습", "퀴즈", "평가".

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Design or troubleshoot telemetry, SLOs, and incident diagnostics. Route to the relevant signal, system boundary, or vendor guide.

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