「dos」の検索結果

Generates complete NHANES-style cross-sectional epidemiology + retrospective clinical validation research designs from a user-provided disease and biomarker direction. Always use this skill whenever a user wants to design, plan, or build a population-level biomarker association study using NHANES or similar survey datasets, especially when the article logic includes disease definition, biomarker formula derivation, multivariable logistic regression, restricted cubic spline analysis, subgroup stability testing, and a secondary hospital-based retrospective validation cohort. Covers five study patterns (cross-sectional association, dose-response / RCS, subgroup-stability, NHANES + retrospective validation, preliminary screening-performance) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path...

日本語の概要は準備中です。原文の説明を表示しています。

Exact detection thresholds for identifying malicious network patterns including port scans, DoS attacks, and beaconing behavior.

日本語の概要は準備中です。原文の説明を表示しています。

Materials science toolkit. Crystal structures (CIF, POSCAR), phase diagrams, band structure, DOS, Materials Project integration, format conversion, for computational materials science.

日本語の概要は準備中です。原文の説明を表示しています。

Turn a source-bound company and market dossier into testable ideal-customer-profile hypotheses, buying roles, triggers, constraints, disqualifiers, standing, counterevidence, and research gaps. Use when a URL, company description, monitor profile, or evidence manifest needs to become defensible ICP inputs for buyer research or an AI-visibility prompt panel.

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Annotate copy number variant segments with overlapping genes, dosage-sensitivity scores, cancer driver databases, population frequencies, and clinical-variant content. Covers bedtools/pybedtools interval intersection, AnnotSV comprehensive annotation and ranking, ClinGen haploinsufficiency/triplosensitivity scoring, gnomAD-SV/DGV frequency filtering, COSMIC Cancer Gene Census, and ClinVar overlap. Use when interpreting which genes a CNV affects, distinguishing the driver gene of a focal event from passengers, filtering against population CNVs, separating whole-gene from partial-gene overlap, or preparing CNVs for clinical classification.

日本語の概要は準備中です。原文の説明を表示しています。

Detect, date, and contextualize whole-genome duplication (WGD / paleopolyploidy) events using wgd v2 (Chen et al 2024), KsRates (Sensalari 2022 substitution-rate-corrected Ks dating), DupGen_finder (Qiao 2019), MAPS (Li 2018 phylogenomic), POInT (Conant 2008 ordered-block), SLEDGe (2024 ML-based), Whale.jl (Bayesian DL+WGD), and synteny-anchored paranome construction. Use when identifying ancient polyploidy from Ks distributions and synteny block analysis, positioning WGD events relative to speciation, distinguishing tandem from segmental from WGD duplications, dating the 2R/3R vertebrate / fish / salmonid WGDs, building paranome and Ks-age mixture models, applying KsRates substitution-rate correction across lineages, or testing alternative biased-fractionation / dosage-balance models post-WGD.

日本語の概要は準備中です。原文の説明を表示しています。

Classify constitutional (germline) copy number variants for clinical reporting using the 2019 ACMG/ClinGen technical standards points-based framework, with ClassifyCNV and AnnotSV for semi-automated scoring. Covers the separate copy-number-loss and copy-number-gain rubrics, the five-tier classification, ClinGen haploinsufficiency/triplosensitivity and dosage-sensitive regions, de novo and segregation evidence, and population-frequency benign evidence. Use when assigning pathogenic/likely-pathogenic/VUS/likely-benign/benign to a constitutional CNV, scoring a CNV against ACMG/ClinGen criteria, or distinguishing the automatable evidence from the case-specific evidence requiring manual input.

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Model gene-family birth-death dynamics across a species tree using CAFE5 (Mendes et al 2020 Bioinformatics 36:5516 gamma-distributed rate categories), CAFE5-error (annotation-error-aware), Count (Csurös 2010 ancestral state reconstruction), BadiRate (Librado 2012 likelihood + parsimony), DupliPHY-Family, and ALE/AleRax (for per-family DTL; see [[gene-tree-species-tree-reconciliation]]). Test lineage-specific gene-family expansions and contractions, distinguish biological dynamics from annotation artifacts, account for assembly fragmentation, identify functional enrichment in expanded / contracted families. Use when correlating gene-family changes with phenotype evolution, ranking lineages by adaptive gene-family-rate shifts, post-WGD dosage-balance analysis, or building Birth-death models from OrthoFinder presence/absence matrices.

日本語の概要は準備中です。原文の説明を表示しています。

Normalizes ChIP-seq data using exogenous spike-in (ChIP-Rx with Drosophila chromatin per Orlando 2014 / Egan 2016; E. coli carryover for CUT&RUN/CUT&Tag). Distinguishes RRPM from Rx-Input scaling, integrates with DiffBind / DESeq2 / edgeR / csaw via sizeFactors and DiffBind library-size vectors, applies the Patel et al 2024 *Nat Biotechnol* failure-mode framework, and validates that normalization is applied at the read level (not peak counts). Use when global signal shifts are expected (HDACi, BETi, EZH2i, dosage, target knockdown), when ChIPseqSpikeInFree detects post-hoc shifts, or when validating internal-control regions before publication.

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Implement AlarmKit alarms and countdown timers for iOS and iPadOS with Lock Screen, Dynamic Island, StandBy, and paired Apple Watch system UI. Covers AlarmManager scheduling, AlarmAttributes and AlarmPresentation, system Stop and AlarmButton secondary actions, authorization, state observation, countdown widget-extension handoff, and Live Activity integration. Use when building wake-up alarms, countdown timers, or alarm-style alerts that need Apple's system alarm experience.

日本語の概要は準備中です。原文の説明を表示しています。

Build alternative browser engines using BrowserEngineKit. Use when developing a non-WebKit browser engine for iOS/iPadOS in supported regions, managing web content/rendering/networking extension processes, configuring GPU and networking process capabilities, checking alternative-engine device eligibility, or reviewing BrowserEngineKit entitlements and Info.plist setup.

日本語の概要は準備中です。原文の説明を表示しています。

Use when collecting or analyzing production iOS or iPadOS performance telemetry with MetricKit, including iOS 27 MetricManager async metric or diagnostic reports, hang or crash triage, custom signposts, extended launch measurement, durable export, or iOS 26 MXMetricManager compatibility.

日本語の概要は準備中です。原文の説明を表示しています。

Add Apple Pencil drawing with PKCanvasView, PKToolPicker, PKDrawing serialization/export, stroke inspection, and PencilKit/PaperKit handoffs. Use when building drawing apps, annotation features, handwriting capture, signature fields, content-version-safe ink workflows, or Apple Pencil-powered experiences on iOS/iPadOS/visionOS.

日本語の概要は準備中です。原文の説明を表示しています。

Unified CloudBase execution guide for all-in-one skill installs. Use this first for CloudBase app tasks, especially existing apps with TODOs, fixed pages, or active handlers. Routes PostgreSQL / CloudBase PG / app.rdb() / queryPgDatabase / managePgDatabase work away from legacy NoSQL and old auth patterns.

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Use when the user has finished building a mobile app, started Metro with `npm run dev`, and wants the running app monitored for runtime errors AND silent failures (empty lists, blank screens, swallowed network errors) and fixed autonomously. Accepts a free-text symptom (e.g., `/debug-app "todos not appearing on home screen"`) to drive persisted-log diagnostics — injects temporary console.log statements at data-path boundaries, reads the sanitized `.powernative/metro-logs/` log, and cleans up logs after the root cause is fixed. Supports port/platform filtering, configurable clean-cycle and timeout limits, and watch-only `--no-fix` mode. Otherwise polls with a durable byte cursor, fixes inline or routes appropriately, verifies each fix from new output, and exits after the configured clean checks (default 3). Foreground loop — blocks the conversation while running. Run only after the app is loaded.

日本語の概要は準備中です。原文の説明を表示しています。

Create premium hand-drawn architecture and process diagrams in the Lanshu animated GIF style, with editable .excalidraw files, static PNG previews, and genuinely animated GIFs with moving flow highlights. Use this skill whenever the user asks for 岚叔动态架构图, Excalidraw-like diagrams, DailyDoseOfDS-style black-background sketches, animated architecture/process GIFs, polished flowcharts, visual explanations of articles or system designs, or asks to replicate or improve a reference diagram with hand-drawn animated effects.

日本語の概要は準備中です。原文の説明を表示しています。

Build or audit a comprehensive brand style guide that documents the full brand system including story, logo system, color, typography, imagery, voice, applications, and dos/don'ts. Use this skill whenever the user wants to create brand guidelines, document an existing brand, build a brand book, audit an existing style guide for completeness, or produce the artifact that other teams will reference for years. Triggers on style guide, brand guidelines, brand book, brand standards, brand manual, style sheet, brand documentation, brand reference. Also triggers when the brand identity is finished and needs to be documented for handoff to designers, developers, vendors, or future team members.

日本語の概要は準備中です。原文の説明を表示しています。

Expert LGPD compliance advisor for Brazil's Lei Geral de Proteção de Dados (Law 13,709/2018). Use this skill whenever a user asks about LGPD, Brazilian data protection, ANPD, personal data processing in Brazil, data subject rights under Brazilian law, legal bases for processing, sensitive data handling, DPO appointment in Brazil, data breach notification to ANPD, LGPD penalties (fines up to 2% of revenue / R$50M), international data transfers from Brazil, Brazil-EU mutual adequacy (January 2026 — SCCs/BCRs no longer needed for Brazil-EU transfers), LGPD gap assessments, privacy policy drafting for Brazilian operations, DPIA under LGPD, consent management, or comparing LGPD with GDPR. Trigger for any Brazil privacy or data protection question even if LGPD is not named explicitly.

日本語の概要は準備中です。原文の説明を表示しています。

Fully automated ship workflow: pre-flight, merge base, run tests, coverage audit, pre-landing review, design review, adversarial review, version bump, CHANGELOG generation, TODOS.md update, bisectable commits, push and PR creation, auto-sync docs via document-release.

日本語の概要は準備中です。原文の説明を表示しています。

Post-ship documentation sync. Updates README, ARCHITECTURE, CONTRIBUTING, CHANGELOG, TODOS, VERSION. Auto-applies factual corrections, asks for risky rewrites. CHANGELOG voice polish. Cross-doc consistency checks.

日本語の概要は準備中です。原文の説明を表示しています。

When the user wants to research, profile, or analyze competitors from their URLs. Also use when the user mentions 'competitor profile,' 'competitor research,' 'competitor analysis,' 'profile this competitor,' 'analyze competitor,' 'competitive intelligence,' 'competitor deep dive,' 'who are my competitors,' 'competitor landscape,' 'competitor dossier,' 'competitive audit,' or 'research these competitors.' Input is a list of competitor URLs. Output is structured competitor profile markdown files. For creating comparison/alternative pages from profiles, see competitors. For sales-specific battle cards, see sales-enablement.

日本語の概要は準備中です。原文の説明を表示しています。

Modélise le raisonnement juridique d'un magistrat français pour l'analyse de dossiers civils. Utiliser ce skill pour analyser un litige et identifier les questions juridiques, construire un raisonnement juridique structuré (syllogisme), rédiger une motivation de jugement civil, rechercher la jurisprudence et les textes applicables via Judilibre et Légifrance, qualifier juridiquement des faits et actes, distinguer prétentions, moyens et arguments. Basé sur les Fiches méthodologiques de rédaction du jugement civil (ENM/Cour de cassation, 2023).

日本語の概要は準備中です。原文の説明を表示しています。

Expert LGPD compliance advisor for Brazil's Lei Geral de Proteção de Dados (Law 13,709/2018). Use this skill whenever a user asks about LGPD, Brazilian data protection, ANPD, personal data processing in Brazil, data subject rights under Brazilian law, legal bases for processing, sensitive data handling, DPO appointment in Brazil, data breach notification to ANPD, LGPD penalties (fines up to 2% of revenue / R$50M), international data transfers from Brazil, Brazil-EU mutual adequacy (January 2026 — SCCs/BCRs no longer needed for Brazil-EU transfers), LGPD gap assessments, privacy policy drafting for Brazilian operations, DPIA under LGPD, consent management, or comparing LGPD with GDPR. Trigger for any Brazil privacy or data protection question even if LGPD is not named explicitly.

日本語の概要は準備中です。原文の説明を表示しています。

Asesor experto en litigación bajo sistemas de derecho civil (civil law) en América Latina. Asiste a abogados litigantes, equipos legales internos y clientes directos con estrategia procesal, análisis de riesgos, opciones tácticas, plazos y orientación sobre el proceso civil en múltiples jurisdicciones. Al final de cada sesión redacta un correo electrónico claro que resume los hallazgos para el cliente.

日本語の概要は準備中です。原文の説明を表示しています。