「retrieval」の検索結果

Generates complete programmed-cell-death (PCD) / regulated-cell-death (RCD) bulk-transcriptome oncology research designs from a user-provided disease and mechanism theme. Always use this skill whenever a user wants to design, plan, or structure a cancer bioinformatics study built around cell-death patterns, tumor microenvironment, prognostic modeling, immune landscape analysis, mutation profiling, and computational drug sensitivity. Covers five study patterns (mechanism-gene-set, subtype-discovery, prognostic-signature, immune-response stratification, translational drug-hypothesis) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path, and a strictly verified reference literature retrieval layer with real references only.

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Generates complete comorbidity-oriented shared-biomarker bioinformatics research designs from a user-provided disease pair and validation direction. Use when a study links two clinically related diseases through shared DEGs, enrichment, PPI hub genes, machine-learning feature selection, public diagnostic validation, gene-regulatory networks, immune infiltration, and optional downstream follow-up. Covers five study patterns (shared-DEG discovery, hub-gene prioritization, machine-learning biomarker selection, immune/regulatory interpretation, multi-layer validation) and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.

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Generates complete conventional single-gene oncology research designs from a user-provided cancer context, target gene, and validation direction. Use when a study centers on a fixed candidate gene and needs expression, prognosis, clinicopathologic association, functional interpretation, immune context, genomic or epigenetic context, optional drug-response hypotheses, and orthogonal validation. Covers five study patterns and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.

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Generates complete process-related diagnostic biomarker bioinformatics research designs from a user-provided disease context, gene-family or pathway theme, and validation direction. Use when a study centers on process-related genes, DEG and WGCNA integration, machine-learning feature selection, nomogram-based diagnostic modeling, immune infiltration, regulatory-network analysis, and optional external or experimental validation. Covers five study patterns (process-DEG discovery, co-expression-module integration, machine-learning biomarker selection, diagnostic model/nomogram workflow, immune-regulatory interpretation and validation) and always outputs Lite / Standard / Advanced / Publication+ with a recommended primary plan, stepwise workflow, figure plan, validation hierarchy, minimal executable version, publication upgrade path, and strictly verified literature retrieval.

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Generates complete cross-disease shared-biomarker bioinformatics research designs from a user-provided disease pair and validation direction. Always use this skill whenever a user wants to design, plan, or build a multi-dataset study linking two related diseases through shared DEGs, enrichment, PPI hub genes, public validation, regulatory-network analysis, immune infiltration, drug-gene interaction screening, and optional qRT-PCR or cell-line validation. Covers five study patterns (shared-DEG discovery, hub-gene prioritization, regulatory-network interpretation, immune/drug follow-up, bioinformatics-plus-validation) and always outputs four workload configs (Lite / Standard / Advanced / Publication+) with recommended primary plan, step-by-step workflow, figure plan, validation strategy, minimal executable version, publication upgrade path, and a strictly verified reference literature retrieval layer with real references only.

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Clarifies a vague clinical or biomedical research idea into a structured, bounded, searchable, researchable, and testable question. Always use this skill whenever a user has an early-stage clinical or research thought, an over-broad topic, an ill-defined evidence question, or an unclear problem statement that must be translated into a question framing suitable for literature retrieval, evidence synthesis, gap analysis, study design, or downstream protocol planning. Never jump straight to answering the substantive medical question unless the user explicitly asks for that. Focus first on question framing, boundary setting, and downstream-ready formulation.

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Identifies real, evidence-audited, topic-specific research gaps in medical research by first retrieving and verifying literature from trusted sources, then mapping the current evidence landscape, rejecting pseudo-gaps, and converting only medium/high-confidence gaps into study-ready research opportunities. Always require real literature retrieval before formal gap claims. Never fabricate references, metadata, or findings.

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Use this skill for setting up vector similarity search with pgvector for AI/ML embeddings, RAG applications, or semantic search. **Trigger when user asks to:** - Store or search vector embeddings in PostgreSQL - Set up semantic search, similarity search, or nearest neighbor search - Create HNSW or IVFFlat indexes for vectors - Implement RAG (Retrieval Augmented Generation) with PostgreSQL - Optimize pgvector performance, recall, or memory usage - Use binary quantization for large vector datasets **Keywords:** pgvector, embeddings, semantic search, vector similarity, HNSW, IVFFlat, halfvec, cosine distance, nearest neighbor, RAG, LLM, AI search Covers: halfvec storage, HNSW index configuration (m, ef_construction, ef_search), quantization strategies, filtered search, bulk loading, and performance tuning.

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Use this skill to implement hybrid search combining BM25 keyword search with semantic vector search using Reciprocal Rank Fusion (RRF). **Trigger when user asks to:** - Combine keyword and semantic search - Implement hybrid search or multi-modal retrieval - Use BM25/pg_textsearch with pgvector together - Implement RRF (Reciprocal Rank Fusion) for search - Build search that handles both exact terms and meaning **Keywords:** hybrid search, BM25, pg_textsearch, RRF, reciprocal rank fusion, keyword search, full-text search, reranking, cross-encoder Covers: pg_textsearch BM25 index setup, parallel query patterns, client-side RRF fusion (Python/TypeScript), weighting strategies, and optional ML reranking.

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Single entry skill for open-websearch setup and focused live retrieval, preferring local CLI/daemon paths while remaining compatible with workspace-exposed MCP tools.

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Fetch and parse LeetCode problems with metadata, constraints, examples, hints, difficulty ratings, and related problems. Integrates with LeetCode API for comprehensive problem data retrieval.

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Query expansion, HyDE, and multi-query generation for improved retrieval

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Cross-encoder reranking and MMR diversity filtering for improved retrieval quality

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Hybrid search combining semantic and keyword retrieval for RAG pipelines. Implement BM25 + dense vector search with fusion strategies.

日本語の概要は準備中です。原文の説明を表示しています。

Perform closed-book frontier reasoning — complex problem solving from internalized knowledge without external retrieval or tool use.

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LangChain retriever implementation with various retrieval strategies for RAG applications

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HNSW vector search for pattern similarity retrieval and knowledge graph maintenance with PageRank scoring, community detection, and 3-tier memory management.

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Observation capture and retrieval across sessions. Stores decisions, discoveries, and bugfix patterns. Searchable via tags and relevance scoring.

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Deterministic handbook-grounded retrieval and thermocouple computations for reflow profile compliance outputs such as ramp, TAL, peak, feasibility, and selection.

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Download water level data from USGS using the dataretrieval package. Use when accessing real-time or historical streamflow data, downloading gage height or discharge measurements, or working with USGS station IDs.

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Guide for setup Serena MCP server for semantic code retrieval and editing capabilities

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Implement efficient similarity search with vector databases. Use when building semantic search, implementing nearest neighbor queries, or optimizing retrieval performance.

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Build Retrieval-Augmented Generation (RAG) systems for LLM applications with vector databases and semantic search. Use when implementing knowledge-grounded AI, building document Q&A systems, or integrating LLMs with external knowledge bases.

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Combine vector and keyword search for improved retrieval. Use when implementing RAG systems, building search engines, or when neither approach alone provides sufficient recall.

日本語の概要は準備中です。原文の説明を表示しています。