596 件 ・ 関連度順
概要と使いどころ
Refine an existing Agiflow task into an unambiguous, testable specification without expanding its intended outcome. Use when a task is vague, lacks acceptance criteria, has unclear scope or dependencies, or is not ready for backlog grooming.
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Daily-scheduled AI news tracker. Collects updates from 80+ AI entities across 6 sources every 24 hours (default 08:00 UTC+8). Generates scored, deduplicated Markdown reports. Supports unattended cron/scheduled execution with date-stamped idempotent output.
日本語の概要は準備中です。原文の説明を表示しています。
Use Waggle automatically as portable, local project memory during meaningful coding work; retrieve prior decisions and constraints, then store only durable outcomes.
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Use when explaining or planning around AISTATS peer review, OpenReview review release, author-reviewer discussion, reviewer volunteer expectations, reviewer confidentiality, decision criteria, meta-review dynamics, the statistician-heavy reviewer pool, and PMLR proceedings outcomes.
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Use when targeting Agriculture, Ecosystems & Environment or deciding whether an agroecosystem-environment manuscript fits this venue. Encodes the journal's fit, the field-to-landscape environmental-outcome bar, data-reporting expectations, house style, official-submission re-check, and desk-reject heuristics.
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Use when explaining or planning around ACM CCS peer review, the two-cycle HotCRP workflow, decision categories including minor revision, the rebuttal window, the adversarial reviewer pool, ethics and disclosure scrutiny, meta-review dynamics, and ACM proceedings outcomes.
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Use when reasoning about how an ACL paper travels through ACL Rolling Review and conference commitment, covering reviewer and area-chair roles, meta-reviews, the commitment decision by senior area chairs and program chairs, Findings versus main-conference outcomes, ethics review escalation, and resubmission strategy across cycles.
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Use when strengthening AAMAS reproducibility evidence for interaction claims, including proofs and game definitions, opponent and population sets, self-play protocols, random seeds, compute, uncertainty on strategic outcomes, baselines, and consistency between what the paper claims about agents and what the artifact can actually show.
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Orchestrate Project Osmos for long-running Fabric and OneLake data-engineering outcomes, including task status, messages, follow-ups, cancellation, and deletion. Osmos tasks are remote service tasks, not local background agents. In Fabric portal Copilot, direct interaction is unsupported; point users to GitHub Copilot CLI. Use spark-cli for direct non-Osmos Spark work. Triggers: "Project Osmos", "Project Osmos task status", "check my Osmos task".
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Mine comments and replies on social posts, videos, and ads for recurring customer language, questions, objections, desired outcomes, complaints, product requests, purchase signals, and creative opportunities. Use for voice-of-customer research grounded in linked source evidence.
日本語の概要は準備中です。原文の説明を表示しています。
AI sales coach composite. Analyzes all available sales data — email campaigns, call recordings/transcripts, reply patterns, pipeline outcomes — to identify what the user does well, where they struggle, and how to improve. Finds patterns in top-performing emails, winning call techniques, successful objection handles, and deal progression. Produces personalized coaching recommendations based on their specific product, market, and selling style. Tool-agnostic.
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Render the logo-equation card ad (7s, 9:16) — partner icon + brand icon joined by a plus sign as an equation, a two-line "= outcome" headline, four numbered steps, and a CTA that hard-cuts in at 2s, on a static black card over timelapse b-roll, no voice. render_card.py draws the two card plates with measured geometry and hard guardrails (the user must confirm the integration is real, no partnership/endorsement/ranking words, no comment-bait CTA, no dashes); compose.py lays the card over the b-roll sped up to read as a timelapse, with an optional bed; measure_motion.py gates the b-roll (a real-time shot reads as a photo). Free, local.
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Use this skill when the user asks to summarize, or asks why Simulink Coverage objectives are missing, unsatisfied, or uncovered on a coverage result they already have — why specific decision, condition, MCDC, relational-boundary, or saturation/overflow outcomes weren't exercised, whether uncovered logic is dead code, or how to close the gap (a test, a coverage filter, or a design change). It reads an existing cvdata, .cvt file, sim-with-coverage output, or Simulink Test result; it never runs cvsim to collect coverage.
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Designs cytosine (CBE, C-to-T) and adenine (ABE, A-to-G) base-editor guides by positioning the target base at the activity-peak of the editing window (protospacer positions ~5-7, PAM-distal numbering), minimizing bystander edits for product purity, reading dinucleotide context (APOBEC1 TC favored / GC disfavored), and selecting the editor variant (BE4max, ABEmax, ABE8e, YE1/SECURE, TadCBE, CGBE, SpG/SpRY-BE). Covers knockout by premature stop (CRISPR-STOP/iSTOP) and splice-site disruption, the three off-target classes (Cas-dependent, Cas-independent DNA, RNA), outcome prediction (BE-Hive/DeepBE), and the base-vs-prime-vs-HDR decision. Use when installing a transition mutation without a double-strand break, knocking out a gene without indels, or choosing CBE vs ABE. Generic guide scoring, prime editing, and HDR donors are separate skills.
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Designs and ranks guide RNAs (sgRNAs) for CRISPR-Cas9/Cas12a gene knockout by scanning a target for PAM sites (NGG SpCas9, NNGRRT SaCas9, TTTV Cas12a, NG SpCas9-NG, near-PAMless SpRY), enumerating candidate spacers, applying hard filters (Pol-III TTTT terminator, 5' G, GC), ranking on-target activity with the context-appropriate model (Rule Set 2/Azimuth for U6/lentiviral, CRISPRscan for T7/embryo, DeepHF for high-fidelity variants, DeepCpf1 for Cas12a), and predicting the indel/frameshift outcome (Bae out-of-frame score, inDelphi, FORECasT, Lindel). Use when selecting sgRNAs to knock out a gene, choosing a nuclease/PAM for a constrained locus, picking which exon to target, or shortlisting guides before an off-target check. Off-target specificity, base/prime editing, and HDR donors are separate skills.
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Quantifies CRISPR editing outcomes with CRISPResso2 (Clement 2019 Nat Biotechnol) across Cas9-nuclease (indels, HDR), CBE and ABE base editors (target conversion + bystander), and prime editor (pegRNA-templated) modes. Covers single-amplicon (CRISPResso), multi-sample batch (CRISPRessoBatch), pooled-amplicon (CRISPRessoPooled), WGS off-target (CRISPRessoWGS), and sample-comparison (CRISPRessoCompare) workflows; quantification-window math that controls what is called edited; substitution-vs-indel diagnostic to distinguish BE from Cas9 contamination; MMEJ deletion pattern interpretation; allele-frequency tables; and failure modes from amplicon misalignment or contamination. Use when quantifying editing from amplicon sequencing, choosing CRISPResso mode by design, distinguishing intended edits from bystanders and indel byproducts, debugging low-alignment runs, or generating publication-grade editing reports.
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Performs logistic regression for clinical trial outcomes (binary, ordinal, multinomial) with marginal-vs-conditional estimand reporting per FDA 2023 covariate adjustment guidance, g-computation/standardisation for marginal effects, modified Poisson for RR, Brant test for proportional odds, Firth penalty for separation, and Hauck-Donner detection. Use when modeling binary or ordinal endpoints in confirmatory or exploratory clinical trials.
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Predicts whether a DNA variant alters mRNA splicing using sequence-based deep-learning tools — SpliceAI (10kb context dilated CNN, clinical default), Pangolin (multi-tissue), MMSplice (modular per-region CNN with calibrated ΔPSI), SpliceTransformer/TrASPr (tissue-aware transformers), SpliceVault (empirical 300K-RNA lookup of likely mis-splicing outcomes), CADD-Splice (composite score). Applies the ClinGen SVI 2023 framework for ACMG/AMP variant interpretation (PVS1, PP3, BP4 evidence codes), HGVS splicing nomenclature (c.123+1G>A, c.123-3T>G, r.spl?), extended-window scoring for deep-intronic pseudoexons, tissue-specific predictions, branchpoint variant detection (BPHunter, LaBranchoR), and splice-switching ASO design. Use when interpreting splice impact of clinical variants, prioritizing VUS, identifying deep-intronic pathogenic variants, or designing ASOs.
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Estimates bivariate genetic correlation (rg) between traits from GWAS summary statistics or individual-level genotypes using cross-trait LDSC, HDL, LAVA, rho-HESS, GREML-bivariate, Popcorn, and HDL-L. Use when quantifying shared genetic architecture between two traits, screening MR validity before causal inference, distinguishing global from locus-level rg, estimating trans-ancestry rg, separating partial from full causation via LCV gcp, or producing a STROBE-MR-compliant cross-trait sensitivity battery. Cross-trait LDSC intercept absorbs sample overlap and is NOT a bias; HDL is biased under sample overlap above ~5%. High rg between exposure and outcome motivates CHP-aware MR sensitivity (CAUSE, LHC-MR).
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Decompose total effects into direct and indirect paths through mediators using mediation, CMAverse 4-way, HIMA/HIMA2 high-dimensional, BAMA, two-step / MVMR mediation, or double-ML medDML. Use when testing whether a molecular phenotype (expression, methylation, protein) mediates a treatment-outcome relationship, decomposing exposure-mediator interaction via VanderWeele 4-way, screening high-dimensional EWAS mediators, or running MR-based mediation when sequential ignorability is implausible.
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Estimate causal effects of an exposure on an outcome from GWAS summary statistics using genetic instruments. Implements IVW (fixed/random), MR-Egger, weighted median/mode, MR-RAPS, CAUSE, GSMR-HEIDI, MR-PRESSO, MVMR, MR-Clust, LCV, and LHC-MR via TwoSampleMR, MendelianRandomization, MR-PRESSO, cause, and lhcMR. Use when testing causal direction between traits, evaluating drug-target effects via cis-pQTL/cis-eQTL, performing multivariable mediation MR, distinguishing causation from correlated horizontal pleiotropy, or producing STROBE-MR-compliant sensitivity batteries.
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Test-driven development for behaviour a unit test cannot reach, by writing the expectation against the running app before writing the code. Declare the consequence first, watch it fail, implement, watch it pass. Use when building a user-facing feature, when the user asks for TDD on UI or full-stack work, when a unit test cannot express the outcome that matters, or when you want a red-green loop that runs against the real app instead of mocks.
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Use when running or scheduling periodic repository review cycles that must dispatch the correct reviewer, aggregate findings, and escalate outcomes into reports, issues, or corrective PRs across API contracts, documentation freshness, code quality, and CloudBase skill quality.
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Generate a CCAM reliability report from session outcomes, hook events, alerts, tool failures, and data freshness. Use for health reviews, incident follow-up, hook-delivery audits, or reliability trend summaries.
日本語の概要は準備中です。原文の説明を表示しています。