Guide for implementing continual learning in AI coding agents — hooks, memory scoping, reflection patterns. Use when setting up learning infrastructure for agents.
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Guide for implementing continual learning in AI coding agents — hooks, memory scoping, reflection patterns. Use when setting up learning infrastructure for agents.
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Recommend a model and a scoped handoff for a task in Claude Code or Codex. Use when choosing who should handle a task, seeking a second opinion, getting unstuck, or delegating focused work; execute one handoff when requested.
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Assess and plan migrations from existing VPN, SWG, or SASE platforms to Cloudflare One, including policy mapping, parity gaps, and rollout.
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Set up, repair, or migrate to Cloudflare Turnstile bot verification in an existing frontend and backend, including server-side Siteverify.
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Calculates molecular descriptors and fingerprints using RDKit. Computes Morgan fingerprints (ECFP), MACCS keys, Lipinski properties, QED drug-likeness, TPSA, and 3D conformer descriptors. Use when featurizing molecules for machine learning or filtering by drug-likeness criteria.
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Protein grouping and inference from peptide identifications. Use when resolving protein ambiguity from shared peptides. Handles protein groups and protein-level FDR control using parsimony and probabilistic approaches.
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Map metabolites to biological pathways using KEGG, Reactome, and MetaboAnalyst. Perform pathway enrichment and topology analysis. Use when interpreting metabolomics results in the context of biochemical pathways.
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Predict B-cell and T-cell epitopes using BepiPred, IEDB tools, and structure-based methods for vaccine and antibody design. Identify immunogenic regions in antigens. Use when designing vaccines, mapping antibody binding sites, or predicting immunogenic peptides.
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Interactive cell type annotation for IMC data. Covers napari-based annotation, marker-guided labeling, training data generation, and annotation validation. Use when manually annotating cell types for training classifiers or validating automated phenotyping results.
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XCMS3 workflow for LC-MS/MS metabolomics preprocessing. Covers peak detection, retention time alignment, correspondence (grouping), and gap filling. Use when processing raw LC-MS data into a feature table for untargeted metabolomics.
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Unsupervised clustering and cell type identification for flow/mass cytometry. Covers FlowSOM, Phenograph, and CATALYST workflows. Use when discovering cell populations in high-dimensional cytometry data without predefined gates.
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Variant calling with GATK HaplotypeCaller following best practices. Covers germline SNP/indel calling, GVCF workflow for cohorts, joint genotyping, and variant quality score recalibration (VQSR). Use when calling variants with GATK HaplotypeCaller.
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Identify likely causal variants within GWAS loci using SuSiE for sum of single effects regression and FINEMAP for shotgun stochastic search. Computes posterior inclusion probabilities and credible sets to prioritize variants for functional follow-up. Use when narrowing GWAS association signals to candidate causal variants or building credible sets for functional validation.
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Call HLA alleles from NGS data using OptiType, HLA-HD, or arcasHLA for immunogenomics applications. Use when determining HLA genotype for transplant matching, neoantigen prediction, or pharmacogenomic screening.
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Query dbSNP for rsID lookups, variant annotations, and cross-references to other databases. Use when mapping between rsIDs and genomic coordinates or retrieving basic variant information.
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Apply Refactoring.Guru-inspired rules when diagnosing code smells, choosing refactoring techniques, and stopping cleanup before uncontrolled redesign.
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Skill that analyzes 18-month scenarios from a news headline. Runs the primary analysis with the scenario-analyst agent and obtains a second opinion with the strategy-reviewer agent. Generates a comprehensive English report covering 1st/2nd/3rd-order impacts, recommended stocks, and a critical review. Example: /scenario-analyzer "Fed raises rates by 50bp" Triggers: news analysis, scenario analysis, 18-month outlook, medium-to-long-term investment strategy
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Expert guidance for systematic backtesting of trading strategies. Use when developing, testing, stress-testing, or validating quantitative trading strategies. Covers "beating ideas to death" methodology, parameter robustness testing, slippage modeling, bias prevention, and interpreting backtest results. Applicable when user asks about backtesting, strategy validation, robustness testing, avoiding overfitting, or systematic trading development.
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Use when the user asks to "codify how our founder sounds", "build a founder voice dossier", or "set our content pillars"; runs an 80%-extraction interview over the user's OWN posts, emails, and decks (never competitor scraping, never an invented persona) and produces the versioned voice record — a per-platform register map (incl. 小红书/微信公众号), banned phrases, per-context disclosure lines (the ECHO C2 upstream), a few-shot bank built exclusively from own posts, and 3-5 content pillars with Estimated %-allocations — submitted via memory/events/channels.ndjson for channel-registry to store as voice-dossier.md, the record every Craft-phase skill reads first. Not for the brand-level voice canon — use brand-language-codifier; not for audience/persona research — use audience-mapper. 声音档案/品牌语气/创始人语气/内容支柱/披露声明
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Use when the user asks to "package our proof points", "build reusable stat cards and case snippets", or "put proof where each pillar makes its claim"; turns claims-ledger-approved proofs into reusable proof modules — stat cards, case snippets, testimonial blocks, comparison proofs — each pinned to a message-house pillar and the ledger claim ID it substantiates, and flags any pillar making a claim with no approved proof behind it. Never adjudicates a proof: unverified or ledger-absent proofs are marked '[needs source]' and routed to the claims candidates. Not for adjudicating or substantiating claims — use offer-claims-registry; not for fabricating a benchmark to fill a gap — a missing proof is flagged, not invented; not for scoring narrative quality — use narrative-quality-auditor. 证据模块/证据卡/客户案例/主张对齐
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Use when the user asks to "build battle cards", "prep the sales team for launch", or "write the internal launch FAQ"; produces the internal enablement kit for a sales-led launch — battle cards vs each named alternative (where we win / where they win / trap questions, every fact traceable), a sales talk track derived from the PR-FAQ spine, an objection-handling table (objection → response → evidence), internal FAQ + CS macros, and an internal launch announcement with embargo discipline. Not for the external message house — use message-house-builder; not for competitor tracking itself — use competitor-tracker or competitor-analysis; not for outbound sequences — use cold-outbound-sequencer. 销售赋能/battle card/销售叙事/异议处理/内部FAQ
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Use when the user asks to "build a message house", "write a PR-FAQ for our launch", or "define the launch narrative and value pillars"; derives from the positioning canvas a message house — tagline, one-liner, three value pillars, per-persona proof points (each labeled Measured / User-provided / [needs source]) — plus a working-backwards PR-FAQ narrative spine (launch-day tense, empty-chair test, five external + five internal FAQs) and per-channel message angle packs (angles, not finished copy). Not for the positioning canvas itself — use positioning-mapper; not for finished blog posts or pages — use content-writer; not for ad or email units — use each discipline creative builder; not for claim adjudication — use offer-claims-registry. 消息屋/PR-FAQ/价值支柱/发布叙事
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Use when the user asks to "is my ad fatiguing", "why is CTR dropping at scale", or "should I rotate creative / widen the audience"; reads frequency, CTR and CVR decay against an early-flight baseline and returns Rotate-creative / Widen-audience / Hold triggers with a per-ad-set fatigue read. Not for building the replacement creative — use ad-creative-builder; not for the RQS score or vetoes — use ad-account-auditor. 广告疲劳检测/频次管理/换素材还是扩人群
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Use when the user asks to "pick a bid strategy", "set a tCPA/tROAS target", or "plan the learning-phase entry"; produces a bid-strategy choice (tCPA / tROAS / max-conversions / manual CPC), the starting target math, a portfolio grouping map, and a learning-phase entry plan. Not for splitting the budget across campaigns — use budget-optimizer; not for in-flight pacing/scale moves — use budget-pacing-monitor; not for scoring the account — use ad-account-auditor. 出价策略/tCPA目标/tROAS/学习期
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