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概要と使いどころ
Download YouTube videos with customizable quality and format options. Use this skill when the user asks to download, save, or grab YouTube videos. Supports various quality settings (best, 1080p, 720p, 480p, 360p), multiple formats (mp4, webm, mkv), and audio-only downloads as MP3.
日本語の概要は準備中です。原文の説明を表示しています。
Build, validate, and troubleshoot deep links for Codex, Cursor, VS Code, Visual Studio, and similar tools. Use when users ask for clickable links (especially in Slack) that open threads, files, folders, or app settings.
日本語の概要は準備中です。原文の説明を表示しています。
Azure Resource Manager SDK for Bot Service in .NET. Management plane operations for creating and managing Azure Bot resources, channels (Teams, DirectLine, Slack), and connection settings.
日本語の概要は準備中です。原文の説明を表示しています。
Azure App Configuration SDK for Java. Centralized application configuration management with key-value settings, feature flags, and snapshots.
日本語の概要は準備中です。原文の説明を表示しています。
Azure App Configuration SDK for Python. Use for centralized configuration management, feature flags, and dynamic settings.
日本語の概要は準備中です。原文の説明を表示しています。
Master modern Angular state management with Signals, NgRx, and RxJS. Use when setting up global state, managing component stores, choosing between state solutions, or migrating from legacy patterns.
日本語の概要は準備中です。原文の説明を表示しています。
Structured guide for setting up A/B tests with mandatory gates for hypothesis, metrics, and execution readiness.
日本語の概要は準備中です。原文の説明を表示しています。
Profiles a genome from raw reads BEFORE assembly with a k-mer spectrum (KMC or Jellyfish histogram), then models it with GenomeScope2 to estimate genome size, heterozygosity, repeat content, and ploidy, and Smudgeplot to infer ploidy from heterozygous k-mer pairs (diploid AB vs triploid AAB vs tetraploid AABB). Covers choosing k via Merqury best_k.sh, the k-mer-coverage vs sequencing-coverage confusion, reading het/repeat/contamination/organelle peaks, why noisy ONT must not be used for counting, and how the estimate becomes the NG50 denominator, the Flye -g value, the hifiasm --hom-cov/purge setting, and the 1.5-2x-too-big haplotig sanity check. Use when starting any de novo assembly, deciding whether short reads can work, estimating genome size for an unknown organism, diagnosing ploidy, or sanity-checking an assembly's size against expectation.
日本語の概要は準備中です。原文の説明を表示しています。
Calls significant loops from protein-directed and targeted 3C assays (HiChIP, PLAC-seq, Capture Hi-C/PCHi-C, ChIA-PET) where the contact background is peak-anchored and coverage-biased, so generic Hi-C loop callers (cooltools dots, Juicer HiCCUPS) use the wrong null. Covers FitHiChIP (config-driven coverage+distance-decay spline regression, peak-to-peak vs peak-to-all foreground, loose vs stringent background, coverage vs ICE bias), MAPS (positive Poisson regression on bias factors for PLAC-seq/HiChIP), hichipper (restriction-site-distance bias model + library QC), CHiCAGO (Delaporte two-component Brownian+technical background for asymmetric bait x other-end Capture Hi-C), the with/without separate-ChIP anchor decision, and differential loops via diffloop. Use when calling loops from HiChIP/PLAC-seq/Capture Hi-C, choosing FitHiChIP/MAPS/CHiCAGO, picking peak-to-all vs peak-to-peak, setting the loop FDR, supplying ChIP peaks as anchors, QCing a HiChIP library, or comparing loops between conditions.
日本語の概要は準備中です。原文の説明を表示しています。
Controls error rates across thousands of simultaneous tests in genomics discovery using false-discovery-rate methods (Benjamini-Hochberg 1995; Benjamini-Yekutieli 2001 for arbitrary dependence; Storey q-value with pi0 estimation; local FDR; independent filtering Bourgon 2010; covariate-weighted FDR via IHW Ignatiadis 2016), plus family-wise error control (Bonferroni, Holm) and the GWAS genome-wide threshold. Covers the FDR-versus-FWER choice as the discovery-versus-confirmatory distinction, the dependence assumptions behind BH (PRDS) versus BY, pi0 estimation, the independent-filtering and false-coverage-rate traps, and reproducibility ranking via IDR (Li 2011). Use when correcting p-values from genome-wide tests, choosing between BH/BY/q-value/Bonferroni, setting an FDR threshold, applying IHW or independent filtering, or interpreting q-values. For confirmatory trials with few pre-specified endpoints (closed testing, graphical/gatekeeping), see clinical-biostatistics/multiplicity-graphical.
日本語の概要は準備中です。原文の説明を表示しています。
Defines cell populations in flow and spectral cytometry through manual gates (rectangle, polygon, quadrant, boolean) and reproducible automated gating (openCyto gating templates, flowDensity data-driven thresholds, flowClust model-based gates), organized as a hierarchical GatingSet (flowWorkspace) and round-tripped with FlowJo via CytoML. Covers the canonical gate order (time -> debris -> singlets -> live -> lineage), FMO-vs-isotype boundary setting, gate-order dependence and recompute semantics, rare-event/MRD gating, and per-population statistics. Use when building a gating strategy, automating a manual FlowJo scheme across samples, choosing manual vs data-driven gates, or extracting population frequencies.
日本語の概要は準備中です。原文の説明を表示しています。
Filter alignments by flags, mapping quality, and regions using samtools view and pysam. Use when extracting specific reads, removing low-quality alignments, or subsetting to target regions.
日本語の概要は準備中です。原文の説明を表示しています。
Installs 425 bioinformatics skills covering sequence analysis, RNA-seq, single-cell, variant calling, metagenomics, structural biology, and 56 more categories. Use when setting up bioinformatics capabilities or when a bioinformatics task requires specialized skills not yet installed.
日本語の概要は準備中です。原文の説明を表示しています。
Use when a carrier asks about trailer types — dry van, reefer, flatbed, step-deck, conestoga, tanker, dump, lowboy, intermodal chassis, auto-hauler. Covers length / weight rules, common specs, reefer unit options (Carrier vs Thermo King), liftgate options, kingpin setting, and trailer-to-tractor matching.
日本語の概要は準備中です。原文の説明を表示しています。
Schema design, normalization decisions, indexing strategies, and migration safety for relational databases. Use when designing tables, choosing between normalize vs denormalize, selecting index types, planning zero-downtime migrations, or setting up connection pooling. Activate on "schema design", "normalization", "denormalization", "foreign key", "index strategy", "migration", "connection pooling", "composite key", "surrogate key", "soft delete", "polymorphic association". NOT for PostgreSQL-specific query tuning or EXPLAIN analysis (use postgresql-optimization), NoSQL or document database design, or cloud database provisioning.
日本語の概要は準備中です。原文の説明を表示しています。
Apply recognition-primed decision making to agents operating under time pressure, uncertainty, and ambiguous cues. Use for situation assessment, RPD-style action selection, and decision-support design in operational settings. NOT for batch optimization, static planning with full information, or tasks where exhaustive search is cheap and harmless.
日本語の概要は準備中です。原文の説明を表示しています。
Apply recognition-primed decision making to agents operating under time pressure, uncertainty, and ambiguous cues. Use for situation assessment, RPD-style action selection, and decision-support design in operational settings. NOT for batch optimization, static planning with full information, or tasks where exhaustive search is cheap and harmless.
日本語の概要は準備中です。原文の説明を表示しています。
Monitors a specified object against explicit stopping criteria and distinguishes replica convergence, iterative progress, and workflow terminal state. NOT for execution or setting goals.
日本語の概要は準備中です。原文の説明を表示しています。
Cloudflare Workers, KV, Durable Objects, and edge computing development. Use for serverless APIs, caching, rate limiting, real-time features. Activate on "Workers", "KV", "Durable Objects", "wrangler", "edge function", "Cloudflare". NOT for Cloudflare Pages configuration (use deployment docs), DNS management, or general CDN settings.
日本語の概要は準備中です。原文の説明を表示しています。
Use when the user wants to design, redesign, shape, critique, audit, polish, clarify, distill, harden, optimize, adapt, animate, colorize, extract, or otherwise improve a frontend interface. Covers websites, landing pages, dashboards, product UI, app shells, components, forms, settings, onboarding, and empty states. Handles UX review, visual hierarchy, information architecture, cognitive load, accessibility, performance, responsive behavior, theming, anti-patterns, typography, fonts, spacing, layout, alignment, color, motion, micro-interactions, UX copy, error states, edge cases, i18n, and reusable design systems or tokens. Also use for bland designs that need to become bolder or more delightful, loud designs that should become quieter, live browser iteration on UI elements, or ambitious visual effects that should feel technically extraordinary. Not for backend-only or non-UI tasks.
日本語の概要は準備中です。原文の説明を表示しています。
Dense UI posture — maximum information density with clear hierarchy. Use when building or reworking admin dashboards, data tables and grids, ops or monitoring views, settings-heavy panels, debug inspectors, state or log viewers, and multi-pane tool UIs someone drives all day.
日本語の概要は準備中です。原文の説明を表示しています。
The TTS/STT/audio-playback system behind the one `speak()` entry point. Use when working on read-aloud, the Listen panel, voice/speed settings, transcription, mic capture, SpeakerButton, iOS playing silence, audio API routes, or files in features/audio/, features/tts/, hooks/tts/, app/api/audio/.
日本語の概要は準備中です。原文の説明を表示しています。
Doctrine for adding a capability INTO a live, existing feature to a world-class bar. Use on 'add X to Y', 'extend Y to support X', a new option, button, setting, endpoint, or tool for Y, or a sub-feature spec to implement. NOT for whole-feature audits or overhauls (use feature-deep-dive).
日本語の概要は準備中です。原文の説明を表示しています。
Context and scope-tagging UI. Use when adding a context picker to a surface, tagging an entity to scopes, setting or filtering by the active (working) context, showing per-entity context status, prompting for context on upload, or editing context-assignment/**, active-context/**, or appContextSlice.
日本語の概要は準備中です。原文の説明を表示しています。