5,154 件 ・ 関連度順
Predict TCR-epitope specificity using ERGO-II and deep learning models for T-cell receptor antigen recognition. Match TCRs to their cognate epitopes or predict TCR targets. Use when analyzing TCR repertoire specificity or identifying antigen-reactive T-cells.
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Score and prioritize neoantigens and epitopes for immunogenicity using multi-factor models combining MHC binding, processing, expression, and sequence features. Rank candidates for vaccine design. Use when prioritizing epitopes for vaccine development or identifying the most immunogenic neoantigens.
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Bisulfite sequencing read alignment using Bismark with bowtie2/hisat2. Handles genome preparation and produces BAM files with methylation information. Use when aligning WGBS, RRBS, or other bisulfite-converted sequencing reads to a reference genome.
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Predict B-cell and T-cell epitopes using BepiPred, IEDB tools, and structure-based methods for vaccine and antibody design. Identify immunogenic regions in antigens. Use when designing vaccines, mapping antibody binding sites, or predicting immunogenic peptides.
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Quality control and normalization for metabolomics data. Covers QC-based correction, batch effect removal, and data transformation methods. Use when correcting technical variation in metabolomics data before statistical analysis.
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Query dbSNP for rsID lookups, variant annotations, and cross-references to other databases. Use when mapping between rsIDs and genomic coordinates or retrieving basic variant information.
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ChIP-seq peak calling using MACS3 (or MACS2). Call narrow peaks for transcription factors or broad peaks for histone modifications. Supports input control, fragment size modeling, and various output formats including narrowPeak and broadPeak BED files. Use when calling peaks from ChIP-seq alignments.
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Track finance investment signal evolution and update logic based on new finance market information. Use when monitoring finance signals and determining if they are strengthened, weakened, or falsified.
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Perform finance web searches and local context searches. Use when the user needs general finance info from the web (Jina/DDG/Baidu) or needs to retrieve finance information from a local document store (RAG).
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Screen post-earnings gap-up stocks for PEAD (Post-Earnings Announcement Drift) patterns. Analyzes weekly candle formation to detect red candle pullbacks and breakout signals. Supports two input modes - FMP earnings calendar (Mode A) or earnings-trade-analyzer JSON output (Mode B). Use when user asks about PEAD screening, post-earnings drift, earnings gap follow-through, red candle breakout patterns, or weekly earnings momentum setups.
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This skill retrieves upcoming earnings announcements for US stocks using the Financial Modeling Prep (FMP) API. Use this when the user requests earnings calendar data, wants to know which companies are reporting earnings in the upcoming week, or needs a weekly earnings review. The skill focuses on mid-cap and above companies (over $2B market cap) that have significant market impact, organizing the data by date and timing in a clean markdown table format. Supports multiple environments (CLI, Desktop, Web) with flexible API key management.
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Use when the user asks to "script this short video", "write a TikTok / Reels / Shorts script", "给这条抖音或视频号视频写脚本", or "fix the hook — viewers drop off in the first seconds"; produces timestamped beat-sheet scripts on the retention-gate model (0-2s hook / 2-5s confirmation / 5-15s payoff / loop-or-CTA) with per-scene script lines, on-screen text for muted viewing, asset keywords, and 9:16 format-param rows per platform norm card for TikTok, Reels, Shorts, 抖音, and 视频号 — plus 2-3 hook options from named hook families and an AI-content disclosure line by default on realistic synthetic media. Spec-only: rendering, TTS, and publishing stay with the user's own tools — no pipelines, no upload automation. Not for creator video briefs — use brief-generator; long-form video SEO belongs to content-writer. 短视频脚本/抖音分镜/开头钩子/竖屏9:16
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Use when the user asks to "triage our comments, DMs, and mentions", "draft replies to this thread", "can we repost this fan post", or "set up inbox SLAs and an escalation path"; produces a ranked triage queue with register detection (sincere / ironic / performative / parasocial, sentiment-inversion table included — "this is so bad" under a comedy register is praise), a commenter taxonomy (troll monitor-only / rager / misguided / unhappy-customer / advocate) with a response-tier ladder and per-channel SLAs, an escalation matrix ending at the crisis path, a moderation ladder plus house rules for owned spaces, and a UGC curation-and-rights mode whose dated permission entries route to the channel registry — every reply is a ranked DRAFT a human posts; nothing is ever auto-sent. Not for launch-window feedback triage — use launch-feedback-synthesizer. 评论私信提及分诊/语域识别/回复草稿/UGC授权
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Use when the user asks to "build the norm card for this platform", "what are the char limits and visible-fold cutoffs here", "is the LinkedIn link-in-first-comment thing documented or folklore", or "which of our platform cards are stale"; maintains the dated, versioned per-platform norm cards in the references/platforms/ pack — char limits, visible-fold cutoffs, hashtag norms, format/aspect specs, link and first-comment placement, disclosure-label mechanics, algorithm emphases (e.g. 小红书 search+saves weighting) — every row labeled platform-documented (official doc, Measured) or Estimated-folklore (named source) with last-verified and review-by dates, and any card past its review date flagged stale rather than trusted. Extends the single pack in place; never forks a second one. Not for picking which channels to run — use channel-portfolio-planner. 平台规范卡/字符限制/折叠线/话题标签/算法侧重/过期标记
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Use when the user asks to "pick a launch date", "plan the launch window", or "set the embargo and lift time"; produces a candidate-window comparison table (conflict / tailwind / risk per window) built from industry-event cycles and the competitor launch calendar, a launch-week vs rolling-release format call, store-review buffer padding (labeled Estimated), and an embargo window definition (lift moment + timezone) submitted to the launch registry as a candidate. Not for judging the cultural moment itself — use trend-spotter; not for launch-day execution — use launch-day-conductor. 发布择时/发布窗口/竞品日历/禁运期窗口/审核缓冲
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Use when the user asks to "build programmatic SEO pages", "generate pages at scale", "rank on a high-authority third-party site", "borrow domain authority", "build a vs / alternative page", "do local SEO", "optimize a Google Business Profile", or "fix NAP" — one page-build router with four modes: programmatic (template × dataset systems), parasite (barnacle publishing on Medium/Reddit/LinkedIn/GitHub), comparison (vs / alternative pages in four formats), and local (GBP + NAP + citations + location pages), each with its own thin/duplicate, honesty, or reputation-abuse guardrail. Not for finding what to target — use keyword-research or content-gap-analysis; not for drafting one standalone article — use content-writer; not for scoring a page for publish — use content-quality-auditor. 程序化SEO/批量页面/寄生SEO/借势权重/对比页/vs页/替代页/本地SEO/谷歌商家档案/NAP一致性
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Use when the user asks to "build a story bank", "collect our origin and customer stories", or "assemble reusable proof stories for the message"; assembles reusable narrative units — origin, founder, customer, transformation, and proof stories — each tagged to a claims-ledger ID and a message-house pillar, with every proof labeled Measured / User-provided / [needs source]. Not for authoring the message house or pillars — use message-system-architect; not for brand voice or naming rules — use brand-language-codifier; not for finished long-form prose — use content-writer; not for adjudicating whether a proof is true — use offer-claims-registry. 品牌故事库/起源客户转化/证据故事单元
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Use when the user asks to "find trending topics", "what trends should my brand jump on", or "time a campaign around a cultural moment"; produces a ranked trend report with brand-fit scores, format calls (rising/peak/declining), a cultural calendar, and go/skip recommendations. Not for finding the creators to run those trends — use influencer-discovery; not for building the brand posting calendar from a go verdict — use social-calendar-builder. 热点趋势洞察/借势营销
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Researches a topic by breaking it into subtopics, gathering factual information with reasoning, and producing a structured summary with key findings and open questions. Use when the user asks to research, investigate, look up, summarize a topic, or says 'what is known about...' or 'learn about...'
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Converts agent definitions between frameworks — exports to Claude Code, OpenAI, CrewAI, Lyzr, and GitHub Models formats, and imports from Claude, Cursor, and CrewAI projects. Use when the user wants to convert an agent, migrate to another framework, export to LangChain/AutoGen/CrewAI, or import from existing automation tools.
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Advanced web search using Tavily API for current information retrieval
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Ingest a raw source document into the wiki. Reads the source, extracts key information, creates or updates wiki pages, maintains cross-references, and logs the operation. Use when the user adds a new source or says 'ingest this'.
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Critique a rendered screen's density — cognitive load, content prioritisation, scanning patterns, and progressive disclosure. Use when a screen feels overwhelming. For the underlying choice-count principle, use `hicks-law` (interaction-design).
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Define what content a product needs, how it is structured, and who owns it. Use when content itself is the problem. For the words in the interface use `ux-writing` (designer-toolkit); for structural hierarchy use `information-architecture`.
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