Polish assemblies and call variants from Oxford Nanopore data using medaka. Uses neural networks trained on specific basecaller versions. Use when improving ONT-only assemblies or calling variants from Nanopore data without short-read polishing.
Filter and select sequences by criteria (length, ID, GC content, patterns) using Biopython. Use when subsetting sequences, removing unwanted records, or selecting by specific criteria.
Query dbSNP for rsID lookups, variant annotations, and cross-references to other databases. Use when mapping between rsIDs and genomic coordinates or retrieving basic variant information.
Fetch upcoming economic events and data releases using FMP API. Retrieve scheduled central bank decisions, employment reports, inflation data, GDP releases, and other market-moving economic indicators for specified date ranges (default: next 7 days). The script outputs raw JSON or text; the assistant filters, assesses impact, and generates the Markdown report.
Detects market top probability using O'Neil Distribution Days, Minervini Leading Stock Deterioration, and Monty Defensive Sector Rotation. Generates a 0-100 composite score with risk zone classification. Use when user asks about market top risk, distribution days, defensive rotation, leadership breakdown, or whether to reduce equity exposure. Focuses on 2-8 week tactical timing signals for 10-20% corrections.
This skill should be used when analyzing recent market-moving news events and their impact on equity markets and commodities. Use this skill when the user requests analysis of major financial news from the past 10 days, wants to understand market reactions to monetary policy decisions (FOMC, ECB, BOJ), needs assessment of geopolitical events' impact on commodities, or requires comprehensive review of earnings announcements from mega-cap stocks. The skill automatically collects news using WebSearch/WebFetch tools and produces impact-ranked analysis reports. All analysis thinking and output are conducted in English.
Generate Minervini-style breakout trade plans from VCP screener output with worst-case risk calculation, portfolio heat management, and Alpaca-compatible order templates (stop-limit bracket for pre-placement, limit bracket for post-confirmation). Use when user has VCP screener results and wants actionable trade plans with entry/stop/target levels and position sizing.
Your long-term knowledge pages. Read them at session start. Create new pages when you learn something worth remembering across sessions. Pages auto-update from your conversations via Hindsight.
Rebuild slide images, scanned or image-based PPT/PPTX files, and PDF decks into object-level editable PowerPoint (.pptx), preserving speaker notes when supplied. Use for making visual slides editable or reconstructing slides from screenshots; not for authoring new presentations from scratch.
Use when the user asks to "remember project context", review saved findings, initialize runtime memory, archive stale work, reconcile notes, or erase a subject; manages authorized HOT/WARM/COLD working memory across all disciplines while preserving registry event ownership and privacy controls. Not for changing canonical registry facts - route those through the owning registry. 项目记忆/跨会话
Design an A/B experiment — hypothesis, variants, primary metric, and sample size. Use when a change can be measured quantitatively at scale. For observing behaviour qualitatively, use `test-scenario`.
Define how the system evolves — contribution model, versioning, deprecation, and change management. Use when multiple teams contribute. For driving uptake use `design-system-adoption` (designer-toolkit); for design file history use `version-control-strategy` (design-ops).
Map one persona's end-to-end experience with stages, touchpoints, emotions, and pain points. Use when improving an existing experience. For the multi-channel ecosystem use `experience-map` (ux-strategy); for screen-level paths use `user-flow-diagram` (prototyping-testing).
Periodic pass that keeps a project's verification skill and feature map honest: parallel source readers per feature, one live session driving every feature, at most one PR of proven corrections. Use for /maintain-verification-skill or "audit the verify skill".
Prepare PRs for review by cleaning noisy history, improving PR descriptions, and adding reviewer guidance without changing code behavior. Use for "make this easy to review", "tidy this PR", "clean up commits", or "annotate the diff".
Apply when introducing a new internal API while old callers still exist. Migrate callers and delete the old API in the same wave instead of preserving compatibility layers.
Remove AI-generated code slop, unnecessary comments, and over-engineering from the current branch diff. Cleans up boilerplate, simplifies abstractions, strips defensive code, and in skill-file mode lints SKILL.md files for quality. Use when cleaning up code, simplifying, removing boilerplate, before committing, or when reviewing a skill before promoting it.
Submit feedback on an Expo skill—or Expo itself—and control bundled anonymous usage telemetry (off by default / opt-in). Submit feedback with: npx --yes submit-expo-feedback@latest "ACTIONABLE_FEEDBACK". Optionally add either or both: --category "CATEGORY" and --subject "SUBJECT". Replace the uppercase placeholders before running. Use when a skill was useful, confusing, broken, missing context, or worth improving; when Expo, Expo CLI, EAS CLI, docs, or MCP worked well or fell short; when an AI agent repeatedly failed, got stuck, or needed the user to take over an Expo task (report it as an eval candidate); or when the user explicitly asks to enable or disable telemetry (tracking), check its status, or understand what it collects.
Migrate an existing Apple/Swift Expo native module from the Expo Modules API 1.0 definition DSL to the 2.0 macro API (sometimes called v2) while preserving its JavaScript and TypeScript contract. Use when converting or incrementally adopting @ExpoModule, @JS, @Event, @SharedObject, or @Record in an existing module. Do not use for creating a new module, general Expo SDK upgrades, or Android/Kotlin migrations.
Onboards RCS Business Messaging and Notify OTP via the pinpoint-sms-voice-v2 AWS CLI. Covers creating a branded RCS test agent (logo, banner, rich cards, suggested replies), adding verified testers, and sending/receiving the first RCS message; and configuring AWS End User Messaging Notify to send one-time-passcode (OTP) verification codes through AWS-managed phone numbers without buying a number or completing carrier registration. Also discovers which registration type a country requires from live API definitions and runs the universal registration lifecycle (create, derive fields, fill, submit, recover from denial, resubmit) shared by 10DLC, toll-free, short code, sender ID, RCS country launch, and Notify tier upgrade. Applicable to RCS agent setup, RCS message send/receive, Notify OTP configuration, verification-code delivery, registration requirements by country, and registration submission. Does not cover WhatsApp (see aws-social-messaging).
Guides Amazon SES onboarding for domain-based email sending. Covers identity configuration, production access, an optional first test send, and troubleshooting setup, authentication, or sending failures. Use when setting up SES, resuming incomplete onboarding, or leaving the sandbox. Does not cover inbound email or Mail Manager, SMS/voice, WhatsApp, SNS, Pinpoint, or WorkMail.
Operate a live AWS workload with AWS DevOps Agent — incident investigation, root-cause analysis, and release-readiness review — for startups with no dedicated DevOps or SRE engineer. Use when a live AWS workload is misbehaving (production is down, 5xx errors, latency spike, timeouts, it broke after the last deploy, an alarm fired, a pasted CloudWatch alarm or stack trace, find the root cause, write a postmortem, no one on call), for pre-merge review (is this PR safe to ship, blast radius), or to set up, pause, stop, or check the cost of AWS DevOps Agent. Detects existing setup first and never re-onboards. Cost, account access, and code egress are each disclosed in one line with safe defaults: cost and access proceed, code egress stays off unless asked. Do not use for: new architecture (architect-for-startups), scaffolding (start-building-for-startups), migrations (gcp-to-aws, azure-to-aws, heroku-to-aws, llm-to-bedrock), or general Activate and credits questions (knowledge-base-for-startups).