「alignment」の検索結果

Advanced Biopython modules for motifs, population genetics, sequence utilities, restriction analysis, clustering, and GenomeDiagram visualization; use when you need extended bioinformatics analysis beyond basic sequence I/O and alignment.

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Generates complete Mendelian randomization study designs from a user-provided exposure and outcome direction. Always use this skill whenever a user wants to design, plan, or build a Mendelian randomization study — even if phrased as "help me write a paper on X", "design an MR study for Y", or "I want to test whether A causally affects B using GWAS". Covers core two-sample MR design, optional bidirectional follow-up, optional multivariable MR, IV selection logic, ancestry alignment, harmonization, IVW as the default primary estimator, weighted median / MR-Egger / MR-PRESSO / leave-one-out sensitivity analyses, Steiger directionality, heterogeneity / pleiotropy checks, and explicit claim-boundary control. Always outputs four workload configs (Lite / Standard / Advanced / Publication+) with a recommended primary plan, stepwise workflow, method rationale, validation ladder, figure plan, minimal executable version, and strictly verified literature guidance with no fabricated references.

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Designs complete research plans that integrate clinical variables with multi-omics data from a user-provided biomedical direction. Always use this skill whenever a user wants to design, scope, or structure a study that combines clinical variables with transcriptomics, proteomics, metabolomics, epigenomics, or related omics layers for mechanism interpretation, biomarker development, risk stratification, treatment-response analysis, or translational use. It should define the clinical use case, alignment across data layers, feature-reduction and fusion logic, modeling route, mechanism-interpretation layer, validation ladder, and four workload configurations (Lite / Standard / Advanced / Publication+). Never fabricate datasets, accession numbers, sample counts, metadata completeness, platform coverage, literature references, PMIDs, DOIs, or validation status. Always include the mandatory Dataset Disclaimer immediately before any workflow section that mentions datasets or public resources.

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Designs QTL colocalization studies that connect eQTL, pQTL, sQTL, or related molecular QTL signals with GWAS loci. Always use this skill whenever a user wants to plan, scope, or structure a locus-level study asking whether a GWAS association and a molecular QTL association may reflect the same underlying causal signal. Covers locus definition, QTL/GWAS source architecture, ancestry and LD alignment, single-locus vs multi-locus strategy, candidate-gene prioritization, optional fine-mapping, linked MR/SMR follow-up, and functional annotation. Always output four workload configurations (Lite / Standard / Advanced / Publication+) with a recommended primary plan, stepwise workflow, method rationale, evidence hierarchy, figure plan, minimal executable version, and strictly verified literature guidance with no fabricated references. Never equate colocalization with causality proof, mediation proof, or automatic target validation. Always include the mandatory Dataset Disclaimer immediately before any workflow section that mentions datasets, repositories, consortia, or public resources.

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Use when evaluating Mark Minervini-style VCP setups: volatility contraction, tight price action, moving-average alignment, relative strength, breakout trigger, and structural stop placement.

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Generate table formatters for structured CLI output with column alignment, borders, and responsive sizing.

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Perform cross-artifact consistency and coverage analysis across constitution, specification, plan, and task artifacts to detect gaps, conflicts, and misalignments before implementation.

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Adversarial plan review by 3 independent reviewers (Feasibility, Completeness, Scope & Alignment) before presenting to user.

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Practical mastering steps for TTS audio: cleanup, loudness normalization, alignment, and delivery specs.

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PromptHub release update skill. Use for `/update-readme`, version bumps, changelog updates, website sync, GUI screenshot/doc refresh, and multilingual release/documentation alignment.

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Adversarial visual-layout audit of a Quarto `.qmd` or Beamer `.tex` deck. Flags overflow, font inconsistency, box fatigue, spacing, and alignment issues. Use when user says "visual audit", "check the layout", "does this overflow?", "look for visual issues", "audit the slides", or after reworking a deck's appearance. Does NOT check writing or pedagogy — pair with `/proofread` or `/pedagogy-review`.

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AI DevKit · Final code review phase guidance for holistic pre-push review. Use when the user wants code review, final lifecycle review, design alignment checks, integration risk review, or dev-lifecycle phase 9.

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Generate high-CTR YouTube thumbnails using Nano Banana 2 via the Arcads external API. Handles reference image upload, character likeness alignment, proven CTR-tested prompt formulas, and parallel batch generation. Use when the user asks to create a YouTube thumbnail, video thumbnail, A/B test thumbnail variations, or refers to thumbnail design with their face, brand assets, or product photos.

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Architect and provision enterprise Azure infrastructure from workload descriptions. For cloud architects and platform engineers planning networking, identity, security, compliance, and multi-resource topologies with WAF alignment. Generates Bicep or Terraform directly (no azd). WHEN: 'plan Azure infrastructure', 'architect Azure landing zone', 'design hub-spoke network', 'plan multi-region DR topology', 'set up VNets firewalls and private endpoints', 'subscription-scope Bicep deployment', 'Azure Backup for VM workloads'. PREFER azure-prepare FOR app-centric workflows.

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Calibrate an LLM judge against human labels using data splits, TPR/TNR, and bias correction. Use after writing a judge prompt (write-judge-prompt) when you need to verify alignment before trusting its outputs. Do NOT use for code-based evaluators (those are deterministic; test with unit tests per `write-code-eval`).

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MUST be used right after changing any CLI color config (delta/bat/themes/lazygit pager) — renders the terminal's colored output to a PNG so Claude can actually SEE contrast, alignment, and highlighting instead of raw ANSI codes. Use for delta git diff colors, bat syntax highlighting, starship prompt, eza/ls colors, or ripgrep matches. Trigger phrases: 看终端效果, 终端截图, 验证配色, terminal screenshot.

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Help users design and facilitate product reviews that shift from status updates to strategic deep-dives, ensuring high-quality craftsmanship and organizational alignment.

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Help users master the art of leading without formal authority by identifying stakeholder incentives, neutralizing conflict through connection, and using co-creation to build shared ownership.

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Help users plan, coordinate, and execute product launches that cut through market noise. This guide covers everything from internal alignment and GACCS briefs to community engagement and viral mechanics.

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Help users define, validate, and operationalize a North Star Metric that bridges the gap between customer value and business success while driving team alignment.

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Help users master the art of proactive communication and alignment with their managers and founders to unlock autonomy, secure resources, and drive business impact.

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Help users establish a multi-layered planning system that balances strategic alignment with operational agility across annual, quarterly, and weekly horizons.

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Help users identify why a team is struggling and implement a structured recovery plan by addressing leadership gaps, individual performance, and structural misalignments.

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Quality assurance specialist for security, performance, accessibility, comprehensive testing, and quality standard alignment. Use for test, review, security audit, OWASP, coverage, lint work, and ISO/IEC 25010 or ISO/IEC 29119-aligned QA recommendations.

日本語の概要は準備中です。原文の説明を表示しています。