「annotations」の検索結果

Build clustered heatmaps for expression matrices and other features-by-samples data with rigorous distance/linkage/scaling choices, robust color mapping, optimal leaf ordering, and ComplexHeatmap/pheatmap/seaborn rendering. Covers the ward.D vs ward.D2 trap, the row-vs-column scaling decision, multi-track annotations, oncoPrint, and raster rendering for large matrices. Use when visualizing expression patterns across samples or identifying co-regulated clusters.

日本語の概要は準備中です。原文の説明を表示しています。

Queries myvariant.info BioThings aggregator for ClinVar, gnomAD, dbSNP, dbNSFP, COSMIC, CADD, and CIViC annotations in batched, version-tracked requests. Use when annotating variant lists from multiple databases simultaneously without managing per-source APIs, and when reproducibility-grade analyses require recording source data versions via _meta.

日本語の概要は準備中です。原文の説明を表示しています。

Estimate SNP heritability and partition it across functional annotations, cell types, and loci from GWAS summary statistics or individual-level genotypes. Implements LDSC, stratified LDSC with the baseline-LD model, Finucane 2018 cell-type prioritization, LDAK SumHer, HDL, HESS local heritability, BOLT-REML, GCTA-GREML, graphREML, and Popcorn cross-population genetic correlation. Use when computing total h2_SNP from summary stats, partitioning heritability across functional categories, prioritizing trait-relevant tissues or cell types from ENCODE/Roadmap chromatin marks, reconciling LDSC vs LDAK enrichment estimates, computing local heritability with HESS, estimating genetic correlation between traits, or producing publication-grade enrichment with calibrated sensitivity to model assumptions.

日本語の概要は準備中です。原文の説明を表示しています。

Parse and analyze multiple sequence alignments using Biopython. Extract sequences, identify conserved regions, analyze gaps, work with annotations, and manipulate alignment data for downstream analysis. Use when parsing or manipulating multiple sequence alignments.

日本語の概要は準備中です。原文の説明を表示しています。

Provides patterns to generate comprehensive REST API documentation using SpringDoc OpenAPI 3.0 and Swagger UI in Spring Boot 3.x applications. Use when setting up API documentation, configuring Swagger UI, adding OpenAPI annotations, implementing security documentation, or enhancing REST endpoints with examples and schemas.

日本語の概要は準備中です。原文の説明を表示しています。

Provides patterns for implementing Spring Boot caching: configures Redis/Caffeine/EhCache providers with TTL and eviction policies, applies @Cacheable/@CacheEvict/@CachePut annotations, validates cache hit/miss behavior, and exposes metrics via Actuator. Use when adding caching to Spring Boot services, configuring cache expiration, evicting stale data, or diagnosing cache misses.

日本語の概要は準備中です。原文の説明を表示しています。

Generate hand-drawn 16:9 article illustrations with the Grav character IP, sparse annotations, and absurd but clear visual metaphors.

日本語の概要は準備中です。原文の説明を表示しています。

Hand-drawn paper-wireframe template — white paper background, monochromatic ink palette, SVG turbulence "wobble" filters for pen-quiver authenticity, handwritten fonts (Caveat / Kalam / Ma Shan Zheng / Long Cang), wavy dividers, sketch-rect overlays, marginalia annotations. For PRD illustrations, IA flow docs, low-fidelity layout exploration, "draft / not final" stakeholder communication. Three skeletons (single-page editorial / app multi-screen flow / IA sitemap) — pick one up front based on the artifact, do NOT inherit only the brush strokes.

日本語の概要は準備中です。原文の説明を表示しています。

Implement custom AEM Workflow Java components on AEM as a Cloud Service. Use when writing WorkflowProcess steps, ParticipantStepChooser implementations, registering services via OSGi DS R6 annotations, reading step arguments from MetaDataMap, accessing JCR payload via WorkflowSession adapter, reading and writing workflow metadata and variables, and handling errors with WorkflowException for retry behavior.

日本語の概要は準備中です。原文の説明を表示しています。

Annotates bacterial and archaeal genomes (isolates, MAGs, plasmids) with Bakta (active versioned databases, NCBI-compliant output) or Prokka (legacy), producing GFF3/GenBank/EMBL/FASTA with INSDC locus tags. Covers Bakta-vs-Prokka-vs-PGAP-vs-DFAST choice, light-vs-full database tiers, translation-table selection (11/4/25), archaeal and leaderless-gene caveats, the small-ORF blind spot, pseudogene-vs-phase-variation, the pangenome re-annotation trap, and submission compliance. Use when annotating a newly assembled prokaryotic genome, choosing an annotation tool, re-annotating a collection for pangenomics, or preparing annotations for NCBI/DDBJ submission.

日本語の概要は準備中です。原文の説明を表示しています。

Query UniProt's REST API (post-2022 endpoint at rest.uniprot.org) for protein sequences, annotations, GO terms, cross-references, ID mappings, and proteomes. Use when fetching UniProtKB entries, navigating the JSON schema, choosing between UniProtKB/UniRef/UniParc/Proteomes resources, deciding stream vs search endpoint for batch retrieval, running ID-mapping jobs with the async pattern, handling isoform suffixes, or filtering reviewed Swiss-Prot vs auto-annotated TrEMBL. Encodes the legacy URL migration (2022), the new JSON schema layout, and bulk-pull patterns.

日本語の概要は準備中です。原文の説明を表示しています。

Assesses the quality and completeness of a genome annotation with BUSCO (conserved single-copy ortholog recovery), OMArk (proteome completeness, consistency, and contamination), CheckM2 (prokaryotic completeness/contamination), and a gene-set sanity panel (gene count, mono-exonic fraction, protein-length distribution, mRNA:gene ratio, coding density). Covers the assembly-BUSCO-vs-proteome-BUSCO diagnostic, what BUSCO-Duplicated really means, why gene count is a vanity metric, and the QC of transferred annotations. Use when judging whether an annotation is good enough to publish or submit, diagnosing a suspect annotation, or comparing annotation completeness across pipelines.

日本語の概要は準備中です。原文の説明を表示しています。

Build clustered heatmaps for expression matrices and other features-by-samples data with rigorous distance/linkage/scaling choices, robust color mapping, optimal leaf ordering, and ComplexHeatmap/pheatmap/seaborn rendering. Covers the ward.D vs ward.D2 trap, the row-vs-column scaling decision, multi-track annotations, oncoPrint, and raster rendering for large matrices. Use when visualizing expression patterns across samples or identifying co-regulated clusters.

日本語の概要は準備中です。原文の説明を表示しています。

Queries myvariant.info BioThings aggregator for ClinVar, gnomAD, dbSNP, dbNSFP, COSMIC, CADD, and CIViC annotations in batched, version-tracked requests. Use when annotating variant lists from multiple databases simultaneously without managing per-source APIs, and when reproducibility-grade analyses require recording source data versions via _meta.

日本語の概要は準備中です。原文の説明を表示しています。

Estimate SNP heritability and partition it across functional annotations, cell types, and loci from GWAS summary statistics or individual-level genotypes. Implements LDSC, stratified LDSC with the baseline-LD model, Finucane 2018 cell-type prioritization, LDAK SumHer, HDL, HESS local heritability, BOLT-REML, GCTA-GREML, graphREML, and Popcorn cross-population genetic correlation. Use when computing total h2_SNP from summary stats, partitioning heritability across functional categories, prioritizing trait-relevant tissues or cell types from ENCODE/Roadmap chromatin marks, reconciling LDSC vs LDAK enrichment estimates, computing local heritability with HESS, estimating genetic correlation between traits, or producing publication-grade enrichment with calibrated sensitivity to model assumptions.

日本語の概要は準備中です。原文の説明を表示しています。

Parse and analyze multiple sequence alignments using Biopython. Extract sequences, identify conserved regions, analyze gaps, work with annotations, and manipulate alignment data for downstream analysis. Use when parsing or manipulating multiple sequence alignments.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill when the user asks about Electronic Logging Device (ELD) compliance under 49 CFR 395.20-38 — ELD mandate, AOBRD vs ELD transition, ELD exemptions, ELD malfunctions, 8-day paper backup, ELD certification on FMCSA registered list, data file integrity, edits + annotations, driver portability, and how to handle ELD failures at roadside. Cite 49 CFR 395.20-395.38.

日本語の概要は準備中です。原文の説明を表示しています。

Adds accessibility annotations (ARIA labels, roles, alt text) to make web content accessible. Use when user asks to "add accessibility", "make accessible", "add aria labels", "wcag compliance", or "screen reader support".

日本語の概要は準備中です。原文の説明を表示しています。

INVOKE THIS SKILL when optimizing, improving, or debugging LLM prompts using production trace data, evaluations, and annotations. Covers extracting prompts from spans, gathering performance signal, and running a data-driven optimization loop using the ax CLI.

日本語の概要は準備中です。原文の説明を表示しています。

Validates models and IOptions. DataAnnotations, IValidatableObject, IValidateOptions<T>.

日本語の概要は準備中です。原文の説明を表示しています。

Trims .NET 8+ apps and libraries. Annotations, ILLink descriptors, IL2xxx warnings, IsTrimmable.

日本語の概要は準備中です。原文の説明を表示しています。

[BETA] Implement custom AEM Workflow Java components on AEM as a Cloud Service. This skill is in beta. Verify all outputs before applying them to production projects. Use when writing WorkflowProcess steps, ParticipantStepChooser implementations, registering services via OSGi DS R6 annotations, reading step arguments from MetaDataMap, accessing JCR payload via WorkflowSession adapter, reading and writing workflow metadata and variables, and handling errors with WorkflowException for retry behavior.

日本語の概要は準備中です。原文の説明を表示しています。

[BETA] AEM Cloud Service expert skill — migrate javax.inject.@Inject fields in Sling Model (@Model) classes to injector-specific annotations (@ValueMapValue / @OSGiService / @SlingObject). Self-discoverable (scan for @Model classes with field-level @Inject); the replacement is chosen deterministically from each field's declared type. Use for "fix @Inject in HeroModel.java", "modernize my Sling Models", or when scanning an AEM project for @Inject misuse. Detailed decision table, companion-annotation handling, import management, and file-level skip policy are in recipe.md. This skill is in beta. Verify all outputs before applying them to production projects.

日本語の概要は準備中です。原文の説明を表示しています。

Set up GitHub Actions CI pipeline with test, lint, type-check, and build jobs for a Node.js/TypeScript project. Includes output grouping, error annotations, and job summary patterns.

日本語の概要は準備中です。原文の説明を表示しています。