Domain-specific authoritative source databases, search strategies by topic category, and source freshness rules
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Domain-specific authoritative source databases, search strategies by topic category, and source freshness rules
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Connect Claude to any app. Send emails, create issues, post messages, update databases - take real actions across Gmail, Slack, GitHub, Notion, and 1000+ services.
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Document database implementation for flexible schema applications. Use when building content management, user profiles, catalogs, or event logging. Covers MongoDB (primary), DynamoDB, Firestore, schema design patterns, indexing strategies, and aggregation pipelines.
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Time-series database implementation for metrics, IoT, financial data, and observability backends. Use when building dashboards, monitoring systems, IoT platforms, or financial applications. Covers TimescaleDB (PostgreSQL), InfluxDB, ClickHouse, QuestDB, continuous aggregates, downsampling (LTTB), and retention policies.
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Graph database implementation for relationship-heavy data models. Use when building social networks, recommendation engines, knowledge graphs, or fraud detection. Covers Neo4j (primary), ArangoDB, Amazon Neptune, Cypher query patterns, and graph data modeling.
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Vector database implementation for AI/ML applications, semantic search, and RAG systems. Use when building chatbots, search engines, recommendation systems, or similarity-based retrieval. Covers Qdrant (primary), Pinecone, Milvus, pgvector, Chroma, embedding generation (OpenAI, Voyage, Cohere), chunking strategies, and hybrid search patterns.
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Data ingestion patterns for loading data from cloud storage, APIs, files, and streaming sources into databases. Use when importing CSV/JSON/Parquet files, pulling from S3/GCS buckets, consuming API feeds, or building ETL pipelines.
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Design and implement Azure cloud architectures using best practices for compute, storage, databases, AI services, networking, and governance. Use when building applications on Microsoft Azure or migrating workloads to Azure cloud platform.
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Configure host-based firewalls (iptables, nftables, UFW) and cloud security groups (AWS, GCP, Azure) with practical rules for common scenarios like web servers, databases, and bastion hosts. Use when exposing services, hardening servers, or implementing network segmentation with defense-in-depth strategies.
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Design Microsoft Orleans systems from each primitive's purpose and failure model. USE FOR: grains, digital twins, state versus databases, transactions, messaging, streams, timers, reminders, Durable Jobs, stateless workers, grain services, startup, and hosting. DO NOT USE FOR: other actor stacks, batches, relational-only CRUD, or advice without an Orleans decision. INVOKES: inspect version and topology, choose the primitive, implement, and validate.
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Comprehensive toolkit for developing with the CocoIndex library. Use when users need to create data transformation pipelines (flows), write custom functions, or operate flows via CLI or API. Covers building ETL workflows for AI data processing, including embedding documents into vector databases, building knowledge graphs, creating search indexes, or processing data streams with incremental updates.
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SQL query optimization and database performance specialist. Use when optimizing slow queries, fixing N+1 problems, designing indexes, implementing caching, or improving database performance. Works with PostgreSQL, MySQL, and other databases.
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PostgreSQL database documentation - SQL queries, database design, administration, performance tuning, and advanced features. Use when working with PostgreSQL databases, writing SQL, or managing database systems.
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Patterns for SQLite databases in Python projects - state management, caching, and async operations. Triggers on: sqlite, sqlite3, aiosqlite, local database, database schema, migration, wal mode.
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This skill should be used when user asks to "query MongoDB", "show database collections", "get collection schema", "list MongoDB databases", "search records in MongoDB", or "check database indexes".
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CLI/Python toolkit for rapid bioinformatics queries. Preferred for quick BLAST searches. Access to 20+ databases: gene info (Ensembl/UniProt), AlphaFold, ARCHS4, Enrichr, OpenTargets, COSMIC, genome downloads. For advanced BLAST/batch processing, use biopython. For multi-database integration, use bioservices.
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Execute database migrations across ORMs and platforms with zero-downtime strategies, data transformation, and rollback procedures. Use when migrating databases, changing schemas, performing data transformations, or implementing zero-downtime deployment strategies.
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Plan and execute database migrations, data transformations, and system migrations safely with rollback strategies and data integrity validation. Use when migrating databases, transforming data schemas, moving between database systems, implementing versioned migrations, handling data transformations, ensuring data integrity, or planning zero-downtime migrations.
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Autonomous biomedical AI agent framework for executing complex research tasks across genomics, drug discovery, molecular biology, and clinical analysis. Use this skill when conducting multi-step biomedical research including CRISPR screening design, single-cell RNA-seq analysis, ADMET prediction, GWAS interpretation, rare disease diagnosis, or lab protocol optimization. Leverages LLM reasoning with code execution and integrated biomedical databases.
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Generate and interpret security-research diffs between Windows versions or patch levels using this repo's WinDiff CLI and databases. Use when comparing Windows builds or binaries such as ntoskrnl.exe, ntdll.dll, win32k*.sys, ci.dll, or cng.sys to find changed syscalls, symbols, types, mitigation flags, callbacks, ETW/EtwTi telemetry, code-integrity behavior, drivers, or attack surface. Explain likely intent and security relevance with Windows-internals knowledge, and frame findings for anti-malware/EDR, anti-cheat, and vulnerability-research audiences rather than returning an uninterpreted symbol list.
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GSEA and over-representation analysis (ORA) for RNA-seq and proteomics. Wraps Enrichr for ORA against MSigDB, KEGG, GO, and 200+ databases; runs preranked GSEA on ranked DE gene lists. Outputs enrichment tables and running-score plots. Use after DESeq2 or edgeR for pathway-level interpretation.
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Query ARCHS4 REST API for uniformly processed RNA-seq expression, tissue patterns, co-expression across 1M+ human/mouse samples. Retrieve z-scores, co-expressed genes, samples by metadata, HDF5 matrices. For variant population genetics use gnomad-database; for pathway enrichment use gget-genomic-databases (Enrichr).
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NCBI GEO access via GEOparse and E-utilities. Search by keyword/organism/platform, download GSE series matrices, parse GPL annotations, extract GSM metadata, load expression matrices into pandas. For single-cell use cellxgene-census; for multi-DB access use gget-genomic-databases.
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Cross-reference compound IDs across 20+ databases (ChEMBL, DrugBank, PubChem, ChEBI, PDB, SureChEMBL, HMDB, DrugCentral, BindingDB) via UniChem REST API. Resolve InChIKeys to source IDs, translate between source-specific IDs, find structurally related compounds by connectivity. POST with a JSON body for all cross-reference queries; only /sources is GET. No auth required.
日本語の概要は準備中です。原文の説明を表示しています。