「editor」の検索結果

Designs cytosine (CBE, C-to-T) and adenine (ABE, A-to-G) base-editor guides by positioning the target base at the activity-peak of the editing window (protospacer positions ~5-7, PAM-distal numbering), minimizing bystander edits for product purity, reading dinucleotide context (APOBEC1 TC favored / GC disfavored), and selecting the editor variant (BE4max, ABEmax, ABE8e, YE1/SECURE, TadCBE, CGBE, SpG/SpRY-BE). Covers knockout by premature stop (CRISPR-STOP/iSTOP) and splice-site disruption, the three off-target classes (Cas-dependent, Cas-independent DNA, RNA), outcome prediction (BE-Hive/DeepBE), and the base-vs-prime-vs-HDR decision. Use when installing a transition mutation without a double-strand break, knocking out a gene without indels, or choosing CBE vs ABE. Generic guide scoring, prime editing, and HDR donors are separate skills.

日本語の概要は準備中です。原文の説明を表示しています。

Quantifies CRISPR editing outcomes with CRISPResso2 (Clement 2019 Nat Biotechnol) across Cas9-nuclease (indels, HDR), CBE and ABE base editors (target conversion + bystander), and prime editor (pegRNA-templated) modes. Covers single-amplicon (CRISPResso), multi-sample batch (CRISPRessoBatch), pooled-amplicon (CRISPRessoPooled), WGS off-target (CRISPRessoWGS), and sample-comparison (CRISPRessoCompare) workflows; quantification-window math that controls what is called edited; substitution-vs-indel diagnostic to distinguish BE from Cas9 contamination; MMEJ deletion pattern interpretation; allele-frequency tables; and failure modes from amplicon misalignment or contamination. Use when quantifying editing from amplicon sequencing, choosing CRISPResso mode by design, distinguishing intended edits from bystanders and indel byproducts, debugging low-alignment runs, or generating publication-grade editing reports.

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Designs pooled sgRNA libraries for CRISPR knockout, interference (CRISPRi), activation (CRISPRa), Cas12a multiplex, base-editor, and prime-editor screens. Covers on-target scoring (Rule Set 2, Azimuth, DeepSpCas9, CRISPRon), off-target scoring (CFD, MIT), TSS-relative positioning for CRISPRi/a (Horlbeck, Dolcetto, Calabrese), PAM-variant chemistries, control-guide composition, oligo cloning architecture, and library QC. Use when choosing a genome-wide library (GeCKOv2 vs Avana vs Brunello vs TKOv3 vs Inzolia), designing a focused or paralog-focused custom library, picking CRISPRi vs CRISPRa TSS windows, deciding control-guide proportions, or diagnosing library skew and dropout in a freshly cloned pool.

日本語の概要は準備中です。原文の説明を表示しています。

Designs and analyzes pooled prime-editor (PE) screens for installing precise genetic variants without bystander confounding. Covers pegRNA design with PRIDICT and PRIDICT2 (Mathis 2023/2024) for predicting per-pegRNA editing efficiency, pegRNA architecture (spacer + scaffold + PBS + RTT), PE2 / PE3 / PE3b / PEmax / PEAR variants, MOSAIC in situ saturation mutagenesis (Hsu JY et al 2024 bioRxiv), the PRIME pooled-screen methodology (Erwood/Doman 2023 Nat Biotechnol 41:885; ~3,699 ClinVar variant screens), chromatin context as a primary determinant of PE efficiency, scaffold-incorporation and indel byproduct quantification with CRISPResso2, and the cross-modal validation strategy of PE + base-editor screens for variant function. Use when designing a pegRNA library for variant installation, choosing between BE and PE for a specific edit, predicting pegRNA efficiency before library synthesis, analyzing PE screen output, distinguishing intended-edit from scaffold-incorporation, or scaling PE screens to thousands of variants.

日本語の概要は準備中です。原文の説明を表示しています。

Generates a comprehensive and best-practice-oriented .editorconfig file based on project analysis and user preferences.

日本語の概要は準備中です。原文の説明を表示しています。

Use when working on the Chat Customizations editor — the management UI for agents, skills, instructions, hooks, prompts, MCP servers, and plugins.

日本語の概要は準備中です。原文の説明を表示しています。

Authors .editorconfig rules. IDE/CA severity, AnalysisLevel, globalconfig, code style enforcement.

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Installs and configures Prettier, ESLint, EditorConfig, and other code quality tools to enforce consistent code style across the team. Generates config files, npm scripts, editor settings recommendations, and CI integration suggestions. Use when users request "setup prettier", "add eslint", "configure code formatting", or "enforce code style".

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参考素材の見た目やカットのリズムを再利用できる設定に整理し、手元の映像の編集計画、画像・動画・3D素材の生成計画、編集可能なタイムラインをオフラインで作るスキル。

• 映像の好みを聞き取り設定にまとめたいとき
• スタイルパックの検証と出所確認
• 参考映像のリズムで編集を計画

撮影済みの動画や画面収録から見どころを選び、カット・構成整理・字幕や音声の追加を進めます。長い録画の短編化からSNS向けの画角調整、編集ソフトでの仕上げまで扱うスキルです。

• 長い録画から見どころを切り出したいとき
• 撮影素材からVlogを作りたいとき
• 製品デモに文字やナレーションを加えたいとき

Generate one- or two-ink editorial print poster images.

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Design banners for social media, ads, website heroes, creative assets, and print. Multiple art direction options with optional generated or supplied visuals. Actions: design, create, generate banner. Platforms: Facebook, Twitter/X, LinkedIn, YouTube, Instagram, Google Display, website hero, print. Styles: minimalist, gradient, bold typography, photo-based, illustrated, geometric, retro, glassmorphism, 3D, neon, duotone, editorial, collage.

日本語の概要は準備中です。原文の説明を表示しています。

Plan a weekly editorial calendar by mapping company goals to publishable topics, owners, status, and verification notes.

日本語の概要は準備中です。原文の説明を表示しています。

Single-image generation skill for posters, key art, and editorial illustrations. Defaults to gpt-image-2 but is provider-agnostic — the same workflow drives Flux, Imagen, or Midjourney via the active upstream tooling. Output is one or more PNG/JPEG files saved to the project folder.

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A consumer-feeling dating / matchmaking dashboard — left rail navigation, ticker bar of community signals, headline KPIs, a 30-day mutual-matches bar chart, and a match-rate trend block. Editorial typography, restrained accent. Use when the brief asks for a "dating site", "matchmaking", "community dashboard", "social network dashboard", or any consumer product where the data is the story.

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WeRead-inspired HyperFrames video template for vertical annual reading reports, personal reading dashboards, book-note recaps, and shareable year-in-review stories. Use when users want a 9:16 HTML-to-MP4 reading report with warm paper texture, editorial Chinese typography, book-page metaphors, data highlights, and deterministic motion.

日本語の概要は準備中です。原文の説明を表示しています。

Swiss-inspired creative-mode presentation template skill with bold editorial typography, high-contrast geometric cards, interactive slide navigation, theme switching, hotspot overlays, and palette choreography in a single-file HTML artifact. Use when users ask for a premium presentation-style landing, a Swiss/brutalist deck look, or a creative launch page with rich interactions.

日本語の概要は準備中です。原文の説明を表示しています。

Swiss-style user-research narrative template in warm-paper editorial aesthetics. Use when users ask for a premium research deck or story-first live artifact with minimalist typography, high-clarity layout, subtle motion, donut breakdowns, and keyboard/click navigation across slides in a single HTML file.

日本語の概要は準備中です。原文の説明を表示しています。

Retro Quarterly Review presentation template in a bold blue + orange editorial language. Use when users ask for a high-impact quarterly review / roadmap deck with heavyweight slab headlines, clean cream paper sections, structured grids, and fast premium motion pacing (3 slides, each hold under 3s in video mode).

日本語の概要は準備中です。原文の説明を表示しています。

Elite UX/UI & Advanced GSAP Motion Engineer. Enforces Python-driven true randomization for layout variance, strict AIDA page structure, wide editorial typography (bans 6-line wraps), gapless bento grids, strict GSAP ScrollTriggers (pinning, stacking, scrubbing), inline micro-images, and massive section spacing.

日本語の概要は準備中です。原文の説明を表示しています。

Clean editorial-style interfaces. Warm monochrome palette, typographic contrast, flat bento grids, muted pastels. No gradients, no heavy shadows.

日本語の概要は準備中です。原文の説明を表示しています。

Teaches the agent to produce D3 charts and interactive data visualizations. A comprehensive D3.js skill with examples across chart types and techniques giving the agent expert-level knowledge to generate complex, interactive visualizations. Useful for editorial dashboards, reports, data-rich prototypes, and explanatory graphics.

日本語の概要は準備中です。原文の説明を表示しています。

Premium brand-kit image generation skill for creating high-end brand-guidelines boards, logo systems, identity decks, and visual-world presentations. Trained for minimalist, cinematic, editorial, dark-tech, luxury, cultural, security, gaming, developer-tool, and consumer-app brand systems. Optimized for intentional logo concepting, refined composition, sparse typography, strong symbolic meaning, premium mockups, art-directed imagery, and flexible grid layouts.

日本語の概要は準備中です。原文の説明を表示しています。

Raw mechanical interfaces fusing Swiss typographic print with military terminal aesthetics. Rigid grids, extreme type scale contrast, utilitarian color, analog degradation effects. For data-heavy dashboards, portfolios, or editorial sites that need to feel like declassified blueprints.

日本語の概要は準備中です。原文の説明を表示しています。