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概要と使いどころ
Specifies best practices, including following RESTful API design principles, implementing responsive design, using Zod for data validation, and regularly updating dependencies. This skill promotes modern coding standards and helps developers write consistent, maintainable code.
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Code quality expert including clean code, style guides, and refactoring
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Query the FDA's public openFDA APIs for post-market drug data — FAERS adverse-event reports, Drugs@FDA approval and submission history, Structured Product Labels including boxed warnings, the National Drug Code directory, recall enforcement reports, and drug shortages. Use this skill to check what a regulator has already concluded about a molecule or its class, to date an approval and count its efficacy supplements, to read an approved indication or boxed warning, and to score a drug-event pair for disproportionate reporting with PRR, ROR, and chi-squared. Also trigger on openFDA, api.fda.gov, FAERS, Drugs@FDA, SPL, NDC, pharmacovigilance, boxed warning, adverse event report, drug recall, or safety signal.
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Design small interfering RNA and antisense oligonucleotide sequences against a transcript, and screen them for the failure modes specific to nucleic-acid drugs. Use this skill to tile a target transcript, apply positional and thermodynamic selection rules including duplex asymmetry and nearest-neighbour melting temperature, scan candidates for seed-region complementarity to off-target transcripts, and lay out a chemical modification pattern — gapmer architecture, 2'-O-methyl and 2'-MOE wings, locked nucleic acid, and phosphorothioate placement. Also trigger on siRNA, antisense oligonucleotide, ASO, gapmer, RNase H, seed region, duplex asymmetry, 2'-MOE, locked nucleic acid, phosphorothioate, or GalNAc conjugate.
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Analyze and engineer protein glycosylation. Scan sequences for canonical N-glycosylation sequons (N-X-S/T with X not proline, including overlapping sites), predict O-GalNAc hotspots, read glycan notation, and reach the curated external tooling (NetNGlyc, NetOGlyc, GlycoShield, GlycoWorkbench, GlyTouCan, GlyConnect). Use this skill for therapeutic antibody glycoengineering and afucosylation for ADCC, Fc glycan control, glycan shielding in vaccine immunogen design, sequon removal or insertion, and half-life engineering through sialylation. Also trigger on N-glycosylation, sequon, NXS/NXT, O-glycosylation, glycoform heterogeneity, afucosylation, high-mannose, GlyTouCan, or WURCS.
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This skill should be used to spawn specialized OpenAI Codex CLI subagents for code review, debugging, architecture analysis, security audits, refactoring, documentation, comparative evidence adjudication, and autonomous /goal runs. It adds each persona through process-local developer instructions while preserving the project's AGENTS.md chain, including during parallel launches. Supports GPT-6-Astra across low, medium, high, xhigh, max, and ultra reasoning with default or priority service tiers, plus GPT-5.6 and GPT-5.5 models. Triggers on 'delegate to Codex', 'Codex Astra', 'Astra subagent', 'Codex subagent', 'code review agent', 'security audit', 'refactor with Codex', 'goal run', 'autonomous goal', 'have Codex weigh this'.
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Render Mermaid diagrams as ASCII/Unicode art for terminal display or as SVG files. Use when visualizing flowcharts, state machines, sequence diagrams, class diagrams, or ER diagrams. Supports 17 themes (including vellum, tokyo-night, catppuccin, nord, dracula, github) plus custom colors via --colors JSON.
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This skill should be used when creating, auditing, or maintaining AGENTS.md files and Codex CLI configuration for any project—including initializing AGENTS.md for cross-agent compatibility (Codex, Cursor, Copilot, Devin, Jules, Amp, Gemini CLI), generating config.toml or .rules files, scaffolding .agents/skills/, converting CLAUDE.md to AGENTS.md, or auditing existing agent configs for bloat and staleness. Complementary to codex-orchestrator (which executes subagents; this skill creates the config files they consume).
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Generate and edit high-quality images using Google's Nano Banana Pro (Gemini 3 Pro Image) AI model. Use this skill when working with AI image generation or editing tasks including (1) Creating images from text prompts with professional quality, (2) Editing existing images with natural language instructions, (3) Multi-turn iterative image refinement, (4) Product photography and marketing visuals, (5) Creating infographics and diagrams with text, (6) Photorealistic and artistic image generation, (7) Batch image generation workflows, (8) Testing and troubleshooting Gemini image generation API. Supports up to 4K resolution, multiple aspect ratios, reference images, and advanced prompting techniques for cinema-quality results.
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Turn product photos and a minimal brief into verified, platform-adapted e-commerce detail-page systems, including product fact review, visual analysis, localized copy, 6-10 module story planning, policy-aware text-free image generation or real-photo routing, deterministic Pillow typography, platform-sized slices, long-page previews, manifests, and automated validation. Supports 淘宝/天猫/京东/拼多多/抖音/小红书/Amazon/AliExpress/Temu/TikTok Shop/eBay/Etsy/Shopify. Use when a user asks for 电商详情页, 商品详情图, 商详设计, A+ content, listing galleries, or a short-input workflow that turns product photos into ready-to-review commerce assets without inventing unsupported claims.
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Rebalances context across Memory, Custom Instructions, knowledge files, and User Preferences in Claude Projects. Audits Memory for redundancy, staleness, and misplacement; prescribes optimization including Codification of stable Memory patterns into explicit User Preferences or Project CI rules. Use when user says "optimize my memory," "what should be in my memory," "trim my knowledge files," "reduce my context usage," "rebalance my project," "what should be in my preferences vs memory," or asks whether something belongs in Memory, a knowledge file, or User Preferences. Also trigger on symptom-phrased: "my project feels bloated," "Claude keeps forgetting things," "my context window keeps hitting limits." Activate whenever Memory-layer balance is the primary concern. Do NOT use for full Project audits (use rootnode-project-audit if available), single-prompt evaluation (use rootnode-prompt-validation if available), or global-layer audits that don't touch Project Memory (use rootnode-global-audit if available).
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Design, build, refactor, or review terminal interfaces—full-screen TUIs, interactive prompts, and command-line tools. Use for terminal-app layout and UX, CLI behavior, ncurses-style tools, dashboards, REPLs, fzf-like pickers, and libraries such as Bubble Tea, Ratatui, Textual, or Ink, including requests that name a known TUI such as lazygit, k9s, btop, helix, or yazi instead of saying “TUI.” Do not use for browser or web UI, native GUI, editor or font configuration, or backend and shell work that has no terminal interface.
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Export and optimize 3D models for FDM/SLA printing including STL/3MF export, mesh integrity verification, wall thickness checking, support generation, and slicing. Use when exporting from CAD or modeling software for 3D printing, verifying STL/3MF files are printable before slicing, troubleshooting models that fail to slice correctly, optimizing part orientation for strength or surface finish, or converting between model formats while preserving printability.
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Release a new version of an R package including version bumping, NEWS.md updates, git tagging, GitHub release creation, and post-release development version setup. Use when a package is ready for a new patch, minor, or major release, after CRAN acceptance to create the corresponding GitHub release, or when setting up the development version bump immediately after a release.
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Step-by-step guidance for DACH-specific governmental procedures including Anmeldung, Finanzamt registration, health insurance enrollment, and social security coordination. Use after arriving in a DACH country and needing to complete mandatory registrations, before a specific appointment to understand what to expect, when an initial registration attempt was rejected, when transitioning between DACH countries, or when handling registrations for dependents alongside your own.
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Build and analyze discrete or continuous Markov chains including transition matrix construction, state classification, stationary distribution computation, and mean first passage times. Use when modeling a memoryless system with observed transition counts or rates, computing long-run steady-state probabilities, determining expected hitting times or absorption probabilities, classifying states as transient or recurrent, or building a foundation for hidden Markov models or reinforcement learning MDPs.
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Formulate a quantum mechanics or quantum chemistry problem with proper mathematical framework including Hilbert space, operators, boundary conditions, and approximation method selection. Use when setting up a quantum mechanics problem for analytic or numerical solution, formulating a quantum chemistry calculation, translating a physical scenario into the Schrodinger or Dirac formalism, or choosing between perturbation theory, variational methods, DFT, and exact diagonalization.
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Instrument applications with OpenTelemetry for distributed tracing, including auto and manual instrumentation, context propagation, sampling strategies, and integration with Jaeger or Tempo. Use when debugging latency issues in distributed systems, understanding request flow across microservices, correlating traces with logs and metrics for root cause analysis, measuring end-to-end latency, or migrating from legacy tracing systems to OpenTelemetry.
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Guide a person through healing modalities including energy work (reiki, chakra balancing), herbal remedies, basic first aid stabilization, and holistic techniques (breathwork, visualization, body scan). AI coaches the practitioner through assessment triage, modality selection, energetic connection, remedy preparation, and integration. Use when a person describes a physical ailment or injury, reports energetic imbalance (fatigue, emotional stagnation), wants coaching through a holistic breathwork or visualization session, or needs post-meditation integration with directed healing attention.
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Implement a generative diffusion model (DDPM or score-based) with noise scheduling, U-Net architecture, training loop, and sampling procedures including DDIM acceleration. Use when building a generative model for image, audio, or molecular synthesis; implementing DDPM from a research paper; adding a custom noise schedule or conditioning mechanism; replacing a GAN-based generator with a diffusion alternative; or prototyping before scaling with production frameworks like diffusers.
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Generate themed Mermaid flowchart diagrams from putior workflow data. Covers theme selection (9 themes including 4 colorblind-safe), output modes (console, file, clipboard, raw), interactive features (clickable nodes, source info), and embedding in README, Quarto, and R Markdown. Use after annotating source files and ready to produce a visual diagram, when regenerating a diagram after workflow changes, or when switching themes or output formats for different audiences.
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Design combinational logic circuits from a functional specification through gate-level implementation. Covers AND, OR, NOT, XOR, NAND, NOR gates; NAND/NOR universality conversions; and standard building blocks including multiplexers, decoders, half/full adders, and ripple-carry adders. Use when translating a Boolean function or truth table into a hardware-realizable gate network and verifying it by exhaustive simulation.
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Solve Diophantine equations (integer-only solutions) including linear, quadratic, and Pell equations. Covers the extended Euclidean algorithm, descent methods, and existence proofs. Use when finding all integer solutions to ax + by = c, solving Pell's equation, generating Pythagorean triples, proving no integer solutions exist via modular constraints, or finding the fundamental solution from which all others are generated.
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Design practical electromagnetic devices including electromagnets, DC and brushless motors, generators, and transformers by bridging theory to application. Use when sizing a solenoid or toroidal electromagnet for a target field or force, selecting motor topology and computing torque and efficiency, designing a transformer for a given voltage ratio and power rating, or analyzing losses from copper resistance, core hysteresis, and eddy currents.
日本語の概要は準備中です。原文の説明を表示しています。