「ppo」の検索結果

The analysis and visualization of alternative splicing (AS) events from RNA sequencing data remains challenging. SpliceWiz is a user-friendly and performance-optimized R package for AS analysis, by processing alignment BAM files to quantify read counts across splice junctions, IRFinder-based intron retention quantitation, and supports novel splicing event identification. We introduce a novel visualization for AS using normalized coverage, thereby allowing visualization of differential AS across

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'treeio' is an R package to make it easier to import and store phylogenetic tree with associated data; and to link external data from different sources to phylogeny. It also supports exporting phylogenetic tree with heterogeneous associated

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A set of tools for working with miRNA affinity models (KdModels), efficiently scanning for miRNA binding sites, and predicting target repression. It supports scanning using miRNA seeds, full miRNA sequences (enabling 3' alignment) and KdModels, and includes the prediction of slicing and TDMD sites. Finally, it includes utility and plotting functions (e.g. for the visual representation of miRNA-target alignment).

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Defines an S4 class for storing data from spatial -omics experiments. The class extends SingleCellExperiment to support storage and retrieval of additional information from spot-based and molecule-based platforms, including spatial coordina

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This package provides classes and methods to support Gene Set Enrichment Analysis (GSEA).

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Provides R wrappers of several on-target and off-target scoring methods for CRISPR guide RNAs (gRNAs). The following nucleases are supported: SpCas9, AsCas12a, enAsCas12a, and RfxCas13d (CasRx). The available on-target cutting efficiency scoring methods are RuleSet1, Azimuth, DeepHF, DeepCpf1, enPAM+GB, and CRISPRscan. Both the CFD and MIT scoring methods are available for off-target specificity prediction. The package also provides a Lindel-derived score to predict the probability of a gRNA to

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Provides S4 classes for general nucleases, CRISPR nucleases, CRISPR nickases, and base editors.Several CRISPR-specific genome arithmetic functions are implemented to help extract genomic coordinates of spacer and protospacer sequences. Commonly-used CRISPR nuclease objects are provided that can be readily used in other packages. Both DNA- and RNA-targeting nucleases are supported.

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The Bandle package enables the analysis and visualisation of differential localisation experiments using mass-spectrometry data. Experimental methods supported include dynamic LOPIT-DC, hyperLOPIT, Dynamic Organellar Maps, Dynamic PCP. It provides Bioconductor infrastructure to analyse these data.

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Seamlessly interfaces the Basic Local Alignment Search Tool (BLAST) to search genetic sequence data bases. This work was partially supported by grant no. R21HG005912 from the National Human Genome Research Institute.

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Save MultiAssayExperiments to h5mu files supported by muon and mudata. Muon is a Python framework for multimodal omics data analysis. It uses an HDF5-based format for data storage.

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Harmonize data management of multiple experimental assays performed on an overlapping set of specimens. It provides a familiar Bioconductor user experience by extending concepts from SummarizedExperiment, supporting an open-ended mix of st

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This package supports functional characteristics of both coding and non-coding genomics data for thousands of species with up-to-date gene annotation. It provides a univeral interface for gene functional annotation from a variety of sources

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Provides delayed computation of a matrix of residuals after fitting a linear model to each column of an input matrix. Also supports partial computation of residuals where selected factors are to be preserved in the output matrix. Implements

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Infrastructure to support 'views' used to classify Bioconductor packages. 'biocViews' are directed acyclic graphs of terms from a controlled vocabulary. There are three major classifications, corresponding to 'software', 'annotation', and '

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Complex heatmaps are efficient to visualize associations between different sources of data sets and reveal potential patterns. Here the ComplexHeatmap package provides a highly flexible way to arrange multiple heatmaps and supports various

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Expert knowledge for Azure Quotas development including limits & quotas. Use when requesting per-region Storage account quota increases, checking limits, or filing Azure support requests, and other Azure Quotas related development tasks. Not for Azure Cost Management (use azure-cost-management), Azure Monitor (use azure-monitor), Azure Policy (use azure-policy), Azure Resource Manager (use azure-resource-manager).

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Expert knowledge for Azure AI Immersive Reader development including best practices, limits & quotas, security, configuration, and integrations & coding patterns. Use when tuning read-aloud/translation, storing user prefs, Entra auth setup, JS SDK integration, or language support, and other Azure AI Immersive Reader related development tasks. Not for Azure AI Language (use azure-language-service), Azure AI Speech (use azure-speech), Azure Translator (use azure-translator), Azure AI services (use microsoft-foundry-tools).

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Cross-skill signal detector - finds entities or themes surfaced independently by 3+ different skill categories within 48h and surfaces them as high-confidence write opportunities

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Scan the ClawHunter agent bounty marketplace for opportunities that genuinely match this agent's real capabilities (code, security research, writing) and surface only real matches — never a raw unfiltered dump. When a match is real audit-shaped work with a linked GitHub repo, the notification carries a one-tap button to dispatch vuln-scanner at it directly.

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Universal tariff calculator for Amazon sellers. Calculate import duties, landed costs, and VAT/GST for any trade route. Supports CN→US, CN→EU, US→EU, EU→US, US→CN and custom origin/destination pairs. Includes Section 301 tariffs, trade agreement rates (USMCA, EVFTA), and HS code lookup. No API key required.

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Amazon sales volume estimator for sellers and product researchers. Estimate monthly sales and revenue from BSR (Best Seller Rank), ASIN, or keyword. Three modes: (A) BSR Calculator — input BSR + marketplace + price + category to get instant sales estimate, (B) ASIN Lookup — input ASIN to auto-fetch data and estimate sales, (C) Keyword Market Analysis — input keyword to analyze total market size and competition. Works on 12 Amazon marketplaces. No API key required. Use when: (1) estimating how many units a product sells per month, (2) sizing a market or niche opportunity, (3) analyzing competitor sales performance, (4) comparing sales across price points, (5) identifying top sellers vs long-tail distribution.

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Amazon competitor monitoring and competitive intelligence for sellers. Track pricing changes, inventory levels, new product launches, review velocity, and advertising patterns for competitor ASINs. Set up monitoring alerts for price drops, stock-outs, and market changes. Works on 12 Amazon marketplaces. No API key required. Use when: (1) monitoring competitor pricing strategies, (2) tracking competitor inventory and stock patterns, (3) detecting new product launches in your category, (4) analyzing competitor review velocity and ratings, (5) identifying market opportunities from competitor gaps, (6) setting up competitive alerts and benchmarks.

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Amazon Brand Analytics interpretation and strategic insights for Brand Registry owners. Decode Search Frequency Rank (SFR) data, analyze Market Basket patterns, interpret Item Comparison reports, and extract demographic insights to optimize product strategy and advertising spend. Works with Brand Analytics data from all Amazon marketplaces. Requires Brand Registry access. Use when: (1) analyzing Search Frequency Rank data for keyword opportunities, (2) interpreting Market Basket data for cross-sell and bundling, (3) understanding Item Comparison competitive positioning, (4) extracting customer demographic insights, (5) optimizing product portfolio based on customer behavior, (6) building data-driven advertising strategies.

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Seller storefront analysis and competitive intelligence for Amazon. Analyzes seller revenue estimation, product portfolio strategy, growth trajectory, and market positioning. Reverse-engineer successful seller strategies and identify expansion opportunities. Use when the user asks about analyzing sellers, competitor seller analysis, seller revenue estimation, storefront analysis, seller strategy, or learning from successful Amazon sellers.

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