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概要と使いどころ
Add a new journal to the MedSci Skills profile database. Extracts metadata from author guidelines, generates write-paper (detailed) and find-journal (compact) profiles in canonical format with quality gates.
日本語の概要は準備中です。原文の説明を表示しています。
Advanced file management tools. Includes batch folder creation, batch file moving, file listing, and HTML author extraction.
日本語の概要は準備中です。原文の説明を表示しています。
Download and transcribe videos from YouTube, Bilibili, TikTok and 1000+ platforms. Use when user requests video download, transcription (转录/字幕提取), or converting video to text/markdown. Supports quality selection, audio extraction, playlist downloads, cookie-based authentication, and AI-powered transcription via SiliconFlow API (免费转录).
日本語の概要は準備中です。原文の説明を表示しています。
Configures JWT Bearer authentication for .NET APIs. Includes token generation, validation, refresh tokens, and user context extraction from claims.
日本語の概要は準備中です。原文の説明を表示しています。
Reads, queries, and writes bigWig indexed binary signal tracks (coverage, fold-change, conservation, methylation-rate) with pyBigWig (Python) and the UCSC Kent tools (bedGraphToBigWig, bigWigToBedGraph, bigWigInfo, bigWigSummary, bigWigAverageOverBed) and deepTools (multiBigwigSummary, computeMatrix, bigwigCompare). Covers the central trap that a wide query returns a precomputed zoom-level summary (by default the mean, which annihilates narrow peaks) not per-base data, when exact=True/values() is mandatory, the NaN-not-zero gap-handling fork, choosing mean vs max vs sum vs coverage by biological question, and the sorted-bedGraph plus chrom.sizes build requirement. Use when extracting signal at regions, computing mean signal per gene/peak, building a browser track from bedGraph, comparing tracks, or building TSS/gene-body metaprofiles.
日本語の概要は準備中です。原文の説明を表示しています。
Assembles haplotype-resolved diploid and telomere-to-telomere (T2T) genomes from PacBio HiFi reads with hifiasm (HiFi-only, Hi-C, or trio phasing) and verkko (HiFi + ultralong ONT for T2T), extracting contigs from GFA and routing phasing QC to k-mer/trio metrics. Covers why a primary assembly is a haplotype mosaic that exists in no cell, partial-vs-full phasing (the .bp. vs .dip. filename convention), the purge-default trap on inbred samples, the --hom-cov coverage-estimate alarm, and verkko-vs-hifiasm for T2T. Use when assembling a diploid eukaryote from HiFi, phasing haplotypes with parents (trio) or Hi-C, deciding whether to chase T2T, or diagnosing switch errors invisible to N50/BUSCO/QV.
日本語の概要は準備中です。原文の説明を表示しています。
Defines cell populations in flow and spectral cytometry through manual gates (rectangle, polygon, quadrant, boolean) and reproducible automated gating (openCyto gating templates, flowDensity data-driven thresholds, flowClust model-based gates), organized as a hierarchical GatingSet (flowWorkspace) and round-tripped with FlowJo via CytoML. Covers the canonical gate order (time -> debris -> singlets -> live -> lineage), FMO-vs-isotype boundary setting, gate-order dependence and recompute semantics, rare-event/MRD gating, and per-population statistics. Use when building a gating strategy, automating a manual FlowJo scheme across samples, choosing manual vs data-driven gates, or extracting population frequencies.
日本語の概要は準備中です。原文の説明を表示しています。
Reads, inspects, and writes Flow Cytometry Standard (FCS) files from conventional, spectral, and mass cytometry (CyTOF), and parses FlowJo/Cytobank/Diva workspaces. Covers FCS 2.0/3.0/3.1/3.2 internals ($PnE linear-vs-log, $DATATYPE, $SPILLOVER vs SPILL vs $COMP, $TIMESTEP), channel/parameter metadata, the silent linearize/truncate defaults, and R (flowCore, flowWorkspace, CytoML) plus Python (FlowKit, readfcs) readers. Use when loading flow or mass cytometry data, mapping detector channels to antibodies, extracting the event matrix, choosing a reader, or bridging FCS to the scanpy/AnnData ecosystem before preprocessing.
日本語の概要は準備中です。原文の説明を表示しています。
Identify recurrent and driver copy number alterations across a tumor cohort with GISTIC2 (G-score, Ziggurat deconstruction, focal vs broad/arm-level analysis, q-values from permutation) and quantify copy-number signatures with the Steele 2022 COSMIC framework and the Drews 2022 CINSignatures framework. Covers driver-gene localization from recurrence peaks, distinguishing focal drivers from arm-level passengers, and the caller-sensitivity caveats of copy-number signatures. Use when finding recurrently amplified or deleted regions in a cohort, localizing driver genes, separating focal from broad events, running GISTIC2, or extracting copy-number mutational signatures.
日本語の概要は準備中です。原文の説明を表示しています。
Build local BLAST databases and run searches using NCBI BLAST+ command-line tools. Use when running >50 queries, building custom databases with -parse_seqids and -taxid, downloading prebuilt NCBI databases via update_blastdb.pl, choosing -task variants (megablast/dc-megablast/blastn/blastn-short), tuning soft/hard masking, scaling threads, or extracting hits with blastdbcmd. Encodes BLAST v5 vs v4 database format, taxonomy filtering, makeblastdb pitfalls.
日本語の概要は準備中です。原文の説明を表示しています。
Build whole-genome alignments using Progressive Cactus (Armstrong 2020 reference-free clade-level WGA), Minigraph-Cactus (Hickey 2024 pangenome-aware), LASTZ chain/net (UCSC pipeline), MUMmer4 (Marçais 2018 pairwise), minimap2 -x asm5/10/20 (Li 2018 fast pairwise), AnchorWave (Song 2022 WGD-aware), and Mauve / progressiveMauve (bacterial). Operates the HAL toolkit (Hickey 2013) for downstream extraction including halSynteny, halLiftover, halBranchMutations, and hal2maf. Use when constructing multi-species alignments for comparative-annotation projection (TOGA), synteny detection, conservation analyses (phyloP / PhastCons), or pangenome graph construction; selecting between reference-free (Cactus) and reference-anchored (LASTZ chains/nets) approaches; tuning sensitivity for closely vs distantly related genomes; or producing HAL files for genome-wide downstream tools.
日本語の概要は準備中です。原文の説明を表示しています。
Preprocess CLIP-seq reads (eCLIP, iCLIP, iCLIP2, iCLIP3, irCLIP, PAR-CLIP, FLASH) with protocol-specific UMI extraction, adapter trimming, length filtering, and post-alignment PCR-duplicate collapse. Use when raw CLIP FASTQ must be turned into deduplicated, crosslink-preserving BAM input for peak calling; choosing between two-pass and single-pass adapter trimming; deciding minimum read length; or mapping UMI patterns to specific eCLIP/iCLIP/iCLIP2/iCLIP3 library preps.
日本語の概要は準備中です。原文の説明を表示しています。
Filter alignments by flags, mapping quality, and regions using samtools view and pysam. Use when extracting specific reads, removing low-quality alignments, or subsetting to target regions.
日本語の概要は準備中です。原文の説明を表示しています。
Parse and analyze multiple sequence alignments using Biopython. Extract sequences, identify conserved regions, analyze gaps, work with annotations, and manipulate alignment data for downstream analysis. Use when parsing or manipulating multiple sequence alignments.
日本語の概要は準備中です。原文の説明を表示しています。
Use when configuring Spring Boot as an OAuth2 resource server, validating JWTs from an external auth provider (Keycloak, Auth0, Okta, Cognito), extracting claims, or implementing scope-based authorization.
日本語の概要は準備中です。原文の説明を表示しています。
Guide for building and refactoring a FastAPI + Prefect + PostgreSQL/pgvector analytics pipeline that extracts insights from chat data using LLM classification, embeddings, UMAP/HDBSCAN clustering, and narrative generation. Use this skill whenever working on this project's codebase — including adding features, refactoring, debugging, creating new endpoints, modifying pipeline stages, or reviewing architecture decisions. Also trigger when the user asks about project structure, stack decisions, async migration, or best practices for this specific system.
日本語の概要は準備中です。原文の説明を表示しています。
Use this skill whenever the user wants to create, read, edit, or manipulate Word documents (.docx) or Word templates (.dotx). Triggers include: any mention of Microsoft Word Documents, such as 'Word doc', 'word document', '.docx', '.dotx', 'microsoft doc'. Also use when extracting or reorganizing content from .docx or .dotx files, inserting or replacing images in documents, find-and-replace in Word files, working with tracked changes or comments, or converting content into a polished Word document. If the user asks for a deliverable as a Word or .docx file (to download, email or print), use this skill. However, if they ask for a document, page, report, memo, or notes WITHOUT naming a file format and the session offers Claude's own dedicated document or page skill or connector, use that instead, even if they will email or print it. Do NOT use for PDFs, spreadsheets, Google Docs, or coding unrelated to document generation.
日本語の概要は準備中です。原文の説明を表示しています。
Azure AI Content Understanding SDK for Python. Use for multimodal content extraction from documents, images, audio, and video.
日本語の概要は準備中です。原文の説明を表示しています。
Azure AI Document Intelligence SDK for .NET. Extract text, tables, and structured data from documents using prebuilt and custom models.
日本語の概要は準備中です。原文の説明を表示しています。
Extract text, tables, and structured data from documents using prebuilt and custom models.
日本語の概要は準備中です。原文の説明を表示しています。
Build image analysis applications with Azure AI Vision SDK for Java. Use when implementing image captioning, OCR text extraction, object detection, tagging, or smart cropping.
日本語の概要は準備中です。原文の説明を表示しています。
AI-driven data extraction from 55+ Actors across all major platforms. This skill automatically selects the best Actor for your task.
日本語の概要は準備中です。原文の説明を表示しています。
Provide comprehensive techniques for penetration testing AWS cloud enprojectnments. Covers IAM enumeration, privilege escalation, SSRF to metadata endpoint, S3 bucket exploitation, Lambda code extraction, and persistence techniques for red team operations.
日本語の概要は準備中です。原文の説明を表示しています。
Reconstruct workflow behind a past coding-agent artifact using local ax sessions/commits/skills/tool traces. Use when asked how X was built.
日本語の概要は準備中です。原文の説明を表示しています。