664 件 ・ 関連度順
概要と使いどころ
Frontend specialist for React, Next.js, TypeScript with FSD-lite architecture, shadcn/ui, and design system alignment. Use for UI, component, page, layout, CSS, Tailwind, and shadcn work.
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Use for AI-assisted Unity work that needs live repo discovery, project-derived routing, runtime-owner proof, runtime-visible output hard stops, runtime numeric proof for repeated visible-output failures, state-step guards, multi-agent scope ownership, modular C#/asmdef safety, UI/scene/visual asset gates, data-first content changes, validation, cleanup proof, or durable workflow rules. Best when agents must prove the actual folder/module/scene/prefab/runtime owner before editing, especially runtime UI, generated assets, code graphs, tutorial/state flows, guided selection/action flows, overlay/dim source-bound mistakes, coordinate conversions, focus/highlight/marker/HUD alignment, predictive lead aiming, ballistic trajectories, spatial IoU verification, or repeated "fix still not visible" failures.
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Use when deciding whether a project is a strong AAAI submission across its broad AI scope, should be reframed or routed to a dedicated track such as AI for Social Impact or AI Alignment, or should instead go to IJCAI, NeurIPS, ICML, ICLR, AISTATS, UAI, ACL, CVPR, KDD, CHI, ICRA, or another specialist venue.
日本語の概要は準備中です。原文の説明を表示しています。
Use when revising an AAAI manuscript for broad-AI-audience fit, a first-page contribution statement legible to non-specialist Phase-1 reviewers, two-column readability, concise novelty claims, reproducibility-checklist alignment, hedged limitations and ethics, and policy-aware framing of AI-system and capability claims.
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Use when working with the Associate Editor and Editor of an Academy of Management Annals (Annals) review — scope alignment after a proposal is invited, what review-article referees evaluate, and revision expectations. Plans the interaction; it does not run the portal preflight (amann-submission) or draft the response letter (amann-revision).
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end cold email outreach orchestration. Handles goal alignment, lead ingestion from any source (CSV, paste, CRM export, database), sequence design, email generation, campaign setup in the user's chosen outreach tool, and launch. Tool-agnostic — supports Smartlead (full MCP automation), Instantly, Lemlist, Apollo, or manual CSV export.
日本語の概要は準備中です。原文の説明を表示しています。
Discover newsletters in a target niche relevant to your ICP, evaluate audience fit, estimate reach and CPM, and output a ranked shortlist of sponsorship opportunities. Uses web search to find newsletters, then scores each against ICP alignment criteria. Use when a marketing team wants to reach an existing engaged audience for less than the cost of building their own, or when testing a new channel before committing.
日本語の概要は準備中です。原文の説明を表示しています。
Assemble a cartoon / animated / hand-crafted music-video ad from a config — a sung song carries the whole narrative while N per-bar i2v clips (one recurring animated character, one look pack) are each cut to their BAR window from librosa beat-tracking and hard-concatenated on the bar, VEED-whisper white bold-sans captions in the BOTTOM third (Alignment 2, above the logo bug, no pill) burned from the song's word timings re-spelled against the locked lyrics, a persistent brand logo bug held over the body (suppressed on the end card), and closed on a solid-brand-color PIL end card with the song still playing under it — never AI-rendered text. This is the FREE deterministic assembly stage (cut-to-bar + hard concat + logo bug + captions + end card + song mux); the song, character, keyframes, and clips come from create-music-elevenlabs / create-image-fal / create-video-fal. Use for the cartoon-music-video format.
日本語の概要は準備中です。原文の説明を表示しています。
Turns Hi-C/Micro-C FASTQ into a deduplicated, filtered .pairs file with pairtools and decides whether the library worked. Covers the bwa mem -SP5M / bwa-mem2 / chromap --preset hic alignment idiom (mates mapped as independent single-end reads), pairtools parse vs parse2 and the walks-policy choice (5unique pairwise vs all for Pore-C/Micro-C concatemers), pair-type classification (keep UU and rescued UC), dedup (PCR vs optical/by-tile), select by pair_type/MAPQ/distance, restriction-fragment handling (restrict, Arima dual-enzyme, Micro-C/DNase fragment-free), and allele-specific phasing (pairtools phase to two coolers). The library-QC decision uses % long-range cis as the one-number quality metric, trans as the noise floor, orientation balance as fragment-map-free dangling-end/self-circle QC, and % duplicates as a complexity proxy. Use when processing Hi-C/Micro-C/Omni-C reads into pairs, judging library quality, handling multi-enzyme or restriction-agnostic protocols, or generating allele-specific contacts.
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Calls germline small variants (SNPs and indels) from Oxford Nanopore and PacBio HiFi long reads with Clair3, a two-stage (pileup + full-alignment) deep-learning caller, selecting the chemistry- and basecaller-version-matched model, enabling read-based phasing, and benchmarking against GIAB with stratification. Covers why the model string is the experiment (no auto-detection, silent degradation on mismatch), why ONT homopolymer/STR indels are the residual error whole-genome F1 hides, and the somatic/trio/RNA boundary to the ClairS/Clair3-Trio family. Use when calling germline SNVs/indels from ONT or HiFi BAMs, choosing a Clair3 model, phasing variants, or benchmarking long-read calls.
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Aligns and QCs methylated-RNA-immunoprecipitation (MeRIP / m6A-seq) IP and input libraries using STAR or HISAT2 splice-aware mapping, samtools sort/index, IP/input matched-pair tracking, antibody-lot metadata recording, replicate concordance via deepTools multiBamSummary + plotCorrelation, IP enrichment QC via plotFingerprint and per-transcript IP/input ratio distributions, library-complexity saturation curves via PreSeq, and the explicit do-NOT-deduplicate convention for standard non-UMI MeRIP. Use when preparing paired IP and input BAM files for exomePeak2 / MeTPeak / MACS3 peak calling, evaluating MeRIP replicate concordance and IP enrichment, deciding whether to deduplicate (standard MeRIP typically NOT), choosing genome-vs-transcriptome alignment for downstream peak vs m6Anet workflows, recording antibody clone and lot metadata for cross-batch reconciliation, detecting failed IPs via saturation curves and IP/input distribution shape, or generating IP-over-Input bigWig tracks for visualisation.
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Detect positive (diversifying / episodic / pervasive) selection using codon dN/dS frameworks. Implements PAML codeml site models (M0/M1a/M2a/M7/M8/M8a), branch models, branch-site model A (Zhang 2005), and HyPhy methods (BUSTED, BUSTED-S, BUSTED-MH, BUSTED-PH, MEME, FEL, FUBAR, aBSREL, SLAC, RELAX, GARD, FUBAR-MH). Includes McDonald-Kreitman framework (asymptotic alpha, impMKT, polyDFE, DFE-alpha, GRAPES) for within-species + divergence inference, RERconverge for trait-correlated rate shifts, CSUBST for convergent substitution, and PhyloAcc for accelerated noncoding evolution. Use when testing adaptive evolution at codons, branches, or full gene; running GARD recombination pre-screen; controlling alignment-error and gBGC false positives; reconciling PAML vs HyPhy results; or performing genome-scale selection scans.
日本語の概要は準備中です。原文の説明を表示しています。
Project gene annotations across genomes using TOGA (Kirilenko 2023 whole-genome-alignment chain-based projection with intactness classification), CESAR 2.0 (Sharma, Schwede & Hiller 2017 codon-aware exon projection), LiftOff (Shumate & Salzberg 2021 reference-based annotation transfer), Liftover (UCSC), GeMoMa (Keilwagen 2019 evidence-based projection), and Comparative Annotation Toolkit (CAT). Use when transferring annotations from a well-annotated reference to query genome(s), classifying gene-loss vs gene-intact across many genomes at scale, building Zoonomia-style comparative annotations across hundreds of mammals or birds (Kirilenko 2023), detecting pseudogenization, projecting alternative isoforms, or selecting between WGA-anchored (TOGA) vs ortholog-based (LiftOff) annotation transfer strategies.
日本語の概要は準備中です。原文の説明を表示しています。
Infer orthologous genes and gene families across species using OrthoFinder3 (HOG-based phylogenetic orthology), SonicParanoid2, Broccoli, ProteinOrtho, OMA / FastOMA hierarchical orthologous groups, eggNOG-mapper, JustOrthologs, and TOGA whole-genome-alignment orthology. Use when building single-copy ortholog sets for phylogenomics, classifying co-orthologs and in/out-paralogs after gene duplication, propagating functional annotation via orthology with awareness of the ortholog conjecture, distinguishing speciation from duplication via gene-tree species-tree reconciliation, computing Quest-for-Orthologs benchmark performance, or running synteny-aware ortholog detection in WGD-affected lineages.
日本語の概要は準備中です。原文の説明を表示しています。
Preprocess CLIP-seq reads (eCLIP, iCLIP, iCLIP2, iCLIP3, irCLIP, PAR-CLIP, FLASH) with protocol-specific UMI extraction, adapter trimming, length filtering, and post-alignment PCR-duplicate collapse. Use when raw CLIP FASTQ must be turned into deduplicated, crosslink-preserving BAM input for peak calling; choosing between two-pass and single-pass adapter trimming; deciding minimum read length; or mapping UMI patterns to specific eCLIP/iCLIP/iCLIP2/iCLIP3 library preps.
日本語の概要は準備中です。原文の説明を表示しています。
Builds and applies 3D pharmacophore models using RDKit Pharm3D, the apo2ph4 receptor-based workflow (Heider et al. 2023), Pharmer / Pharmit for search, and PharmacoForge for protein-pocket-conditioned pharmacophore generation (Flynn et al. 2025), covering ligand-based pharmacophores from active-set alignment and receptor-based pharmacophores from binding-pocket geometry. Explicitly handles feature types, geometric tolerances, partial matching, and pharmacophore-based virtual screening. Use when identifying scaffold-hopping candidates, building shape-and-feature search queries, or transferring SAR across chemotypes.
日本語の概要は準備中です。原文の説明を表示しています。
Calls ChIP-seq peaks with MACS3, MACS2, HOMER, or SPP across narrow (TF) and broad (histone) modes. Handles input control matching, fragment-size modeling vs --nomodel, effective genome size, ENCODE-style IDR vs naive overlap, hyper-ChIPable artifacts, and aligner-specific shifts. Use when calling peaks from ChIP-seq alignments, choosing between narrow vs broad mode for a histone mark, deciding model vs nomodel for low-depth data, applying ENCODE pseudoreplicate IDR, or reconciling MACS vs HOMER vs SPP results.
日本語の概要は準備中です。原文の説明を表示しています。
Performs 3D shape-based similarity searching using ROCS (OpenEye), USRCAT (ultra-fast), Open3DAlign (RDKit), ESPSim (electrostatic), and ShaEP with explicit handling of Tanimoto-Combo (shape + color), shape vs ECFP4 complementarity, conformer-ensemble searching, alignment optimization, and scaffold hopping. Use when searching for shape-mimicking compounds with different scaffolds, identifying bioisosteric replacements, prospective scaffold hopping, or expanding hit series beyond 2D similarity.
日本語の概要は準備中です。原文の説明を表示しています。
Trim PCR primers from aligned reads in amplicon-panel BAMs using samtools ampliconclip. Use when processing SARS-CoV-2 ARTIC, hereditary cancer panels, ctDNA hot-spot panels, or any amplicon assay where primer-derived bases would falsely confirm reference at primer footprints.
日本語の概要は準備中です。原文の説明を表示しています。
Align protein structures using Foldseek 3Di, TM-align, US-align, DALI, or Foldmason for structural MSA. Predict, score, and superpose backbone coordinates when sequence identity is below the twilight zone or remote-homology detection is required. Use when sequence MSA fails (<25% identity), when the dark proteome is the target, when AlphaFoldDB / ESM Atlas search is needed, or when structural superposition is the goal.
日本語の概要は準備中です。原文の説明を表示しています。
Mark and remove PCR/optical duplicates using samtools fixmate and markdup. Use when preparing alignments for variant calling or when duplicate reads would bias analysis.
日本語の概要は準備中です。原文の説明を表示しています。
Generate consensus sequences and manage reference files using samtools. Use when creating consensus from alignments, indexing references, or creating sequence dictionaries.
日本語の概要は準備中です。原文の説明を表示しています。
Select and use Audio Toolbox acoustic, psychoacoustic, and speech quality metrics. Use when computing loudness, sharpness, roughness, fluctuation strength, noise criteria (NC/RNC/RC), speech transmission index (STI), speech intelligibility index (SII), speech quality (ViSQOL, STOI), SPL, reverberation time (RT60), tone-to-noise ratio, or prominence ratio. Also use when asked about PESQ, POLQA, calibration factor, EBU R 128, LUFS, HVAC noise, background noise evaluation, or how to measure audio quality or noise compliance. Covers calibration, standard selection, signal alignment, and the complete function inventory including what does NOT exist.
日本語の概要は準備中です。原文の説明を表示しています。
Import recorded driving sensor data (GPS, camera, lidar, actor tracks, lanes) into scenariobuilder.* objects (GPSData, CameraData, LidarData, ActorTrackData, Trajectory, laneData) and run preprocessing — synchronize, offset correction, crop, normalizeTimestamps, convertTimestamps. Also: compute actor tracks from lidar when no annotations exist, attach camera/lidar mounting + intrinsics, export to MAT/workspace/timetable/script. Use for raw driving dataset files (KITTI, nuScenes, Waymo, Pandaset, ROS/ROS2 bags, .mat, .csv, .mp4) or driving/vehicle/sensor logs that need wrapping. drivingLogAnalyzer (DLA) is OPT-IN ONLY — invoke only on explicit user request ('DLA', 'open in DLA', 'inspect/explore/analyze the recording') or reported sensor problem (sync drift, timestamp mismatch, overlay misalignment). NEVER auto-launch DLA after wrapping (Rule 0). For 'build scenario / export to RoadRunner / drivingScenario / OpenSCENARIO / Unreal / simulate', hand off to matlab-use-scenario-builder.
日本語の概要は準備中です。原文の説明を表示しています。