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概要と使いどころ

Analyzes base-editing screens for variant function. Covers library design (Hanna 2021 ClinVar-scale CBE screen benchmarked on BRCA1/2, Cuella-Martin 2021 DDR saturation), CBE vs ABE chemistry choice (BE3/BE4 vs ABE7.10/ABE8.20/ABE8e), editing-window math (positions 4-8 from PAM-distal end; 4-7 for ABE7.10), bystander-edit quantification and the variant-call ambiguity it creates, sgRNA-efficiency filtering before hit calling, indel byproduct interpretation, the substitution-vs-indel diagnostic, variant annotation against ClinVar / COSMIC, and the Broad be-validation-pipeline. Use when designing a BE variant screen, choosing CBE vs ABE for a specific edit, interpreting bystander-confounded hits, distinguishing functional signal from indel artifact, integrating CRISPResso2 output with screen scoring, or deciding BE vs PE for SNV installation.

日本語の概要は準備中です。原文の説明を表示しています。

lilinji/GeneTind-Life-Skills142026年8月21日 更新

scenario

無料

Write executable failing tests from a recipe handed to you by the main context. Used by `/tdd` Step 2 and ad-hoc when a phase needs tests-first to drive implementation. Decisions about which scenarios to cover, which categories matter, and which fixtures to use are made by the caller — this skill executes that recipe with code-structure discipline.

日本語の概要は準備中です。原文の説明を表示しています。

friedbotstudio/baseline142026年10月13日 更新

aeo

無料

Answer Engine Optimization (AEO) skill — optimize content to be cited by AI language models (ChatGPT, Perplexity, Claude, Gemini, Mistral) as authoritative sources. Distinct from SEO — AEO optimizes for citation in LLM-generated responses, not search rankings. Use when planning content for AI-first search audiences, auditing existing content for E-E-A-T signals, tracking which pages get cited by which LLMs, or building a citation-friendly content strategy. Triggers — 'AEO audit', 'optimize for ChatGPT', 'get cited by Perplexity', 'LLM citation strategy', 'answer engine optimization', 'content for AI search', 'E-E-A-T audit'. Output is a markdown audit report (default) or JSON for pipeline integration. Stdlib-only Python tools.

日本語の概要は準備中です。原文の説明を表示しています。

sinhoneyy/master-skills142026年9月5日 更新

Simple time display for Abby.

日本語の概要は準備中です。原文の説明を表示しています。

luokai0/ai-agent-skills-by-luo-kai122026年5月6日 更新

Expert-level plasma physics knowledge. Use when working with plasma state, Debye shielding, plasma oscillations, magnetohydrodynamics, plasma confinement, fusion plasmas, space plasmas, plasma waves, or plasma instabilities. Also use when the user mentions 'plasma', 'Debye length', 'plasma frequency', 'MHD', 'magnetic confinement', 'tokamak', 'plasma instability', 'Alfven wave', 'Langmuir probe', 'ionosphere', or 'solar wind'.

日本語の概要は準備中です。原文の説明を表示しています。

luokai0/ai-agent-skills-by-luo-kai122026年5月6日 更新

Babysit a GitHub pull request after creation by continuously polling review comments, CI checks/workflow runs, and mergeability state until the PR is merged/closed or user help is required. Diagnose failures, retry likely flaky failures up to 3 times, auto-fix/push branch-related issues when appropriate, and keep watching open PRs so fresh review feedback is surfaced promptly. Use when the user asks Codex to monitor a PR, watch CI, handle review comments, or keep an eye on failures and feedback on an open PR.

日本語の概要は準備中です。原文の説明を表示しています。

browser-use/browser-harness-tui122026年10月13日 更新

Preview a signed-off design one release phase at a time — cut it down into a series of phase screens, each showing only what exists by that phase with the layout untouched, then put them on a scrubber you drag to watch the screen fill in release by release. Use when the user wants a Phase 1 / MVP version of an existing wireframe or mockup, phased or staged screens, a design sliced by release phase or story map, or wants to see what a screen looks like before later features land.

日本語の概要は準備中です。原文の説明を表示しています。

Cavalry-Collective/visual-stack112026年10月10日 更新

ruby

無料

Appwrite Ruby SDK skill. Use when building server-side Ruby applications with Appwrite, including Rails and Sinatra integrations. Covers user management, database/table CRUD, file storage, and functions via API keys.

日本語の概要は準備中です。原文の説明を表示しています。

appwrite/claude-plugin102026年8月19日 更新

safe-by-default-architect

無料日本語概要

再発しやすい危険な実装パターンを、安全側に倒れる標準パターン・禁止事項・共通層・静的ルール候補へ 変換するスキル。ORM強制、deny-by-default認可、サービス経由I/O、永続化確認後の成功表示などを設計する。 レビューで危険コードを見つけるのではなく、危険コードを書きにくくする設計標準を作ることが目的。 Use when turning repeated defect patterns into safe architectural defaults, forbidden-to-safe mapping tables, common layer designs, and enforceable static analysis rules.

takusaotome/claude-skills-library92026年10月5日 更新

Reads a cash forecast (spreadsheet, model export, pasted table or the narrative that accompanies it) and returns a DRAFT assumptions sheet: every assumption the forecast rests on, stated or implied by the figures, with its value as read, its location in the model, the cash lines it drives, its stated source or "not stated", the evidence that would test it, an owner, and one neutral challenge question, so a reviewer can work through the assumptions one by one. Use when the user asks to "list the assumptions behind this cash forecast", "what is this cash flow forecast assuming", "prepare the challenge questions for the treasury review", "pull out the drivers of the 13-week cash forecast" or "build an assumptions register for the liquidity plan". Do not use for actuals against budget by line, use budget-variance-explainer instead; do not use for the case behind a capital request, use capex-request-pack instead. Drafts for human review; never approves, authorises or signs off.

日本語の概要は準備中です。原文の説明を表示しています。

kesslernity/awesome-copilot-agent-skills82026年9月19日 更新

Operational guide for the base+pro → Content Graph ecosystem port loop — porting Pro addon files byte-identical into plugins/nvoos-content-graph-pro cluster-by-cluster (transform rules, byte-identity verifier, standalone-only wiring, dual-matrix validation, tracker updates, PR + self-merge). Use when the user asks to "continue the loop", "do the next cluster", "port <toolkit> to CG Pro", or resumes a Wave E/F port session.

日本語の概要は準備中です。原文の説明を表示しています。

nvdigitalsolutions/mcp-ai-wpoos72026年10月14日 更新

Use when the user asks to "run the weekly social readout", "which denominator does our engagement rate use", or "which posts won this week and what changes next cycle"; produces the organic-social metric dictionary (every rate names its denominator — ERR engagement-by-reach vs ERI by-impressions vs ER-by-follower — locked across periods), median-not-mean per-post rollups with organic and boosted separated, EMV as labeled exec-translation only (never inside any score), an attributed CHAOSS/Orbit-style community-health readout with employees excluded, and the best/worst-performer write-back the next calendar cycle consumes. Not for dollar-ROI math or the ECHO profile result gate verdict — use roi-calculator and social-quality-auditor. 社媒周报/互动率分母/指标字典/复盘回写

日本語の概要は準備中です。原文の説明を表示しています。

unempyd/revenueos72026年9月14日 更新

在授权渗透测试中挖掘认证/授权绕过(authentication & authorization bypass)。当目标的登录、SSO/OAuth/SAML、2FA、会话、密码重置、邮箱验证等鉴权环节可能被逻辑缺陷或解析差异绕过时使用——典型场景:SAML 签名/entityId 绕过、OAuth `response_type`/`redirect_uri` 篡改窃取 token、邮箱规范化/预验证绕过、2FA 可预测/可跳过、会话类型混淆。适用目标类型 Web / REST API / SSO。触发场景包括用户说"测下认证绕过""这个 SAML/OAuth 有没有问题""能不能跳过 2FA""邮箱验证能绕吗"。输出:绕过路径 + 越权访问证据的 finding(含 killed 记录)。

日本語の概要は準備中です。原文の説明を表示しています。

galact-byte/galact-Skills72026年10月13日 更新

Build taste through volume of output, deliberate failure, and speed. Taste cannot be developed by watching. It's sharpened by making, failing, and making again. Use when designing practice routines, breaking through creative blocks, or helping someone move from analysis to execution.

日本語の概要は準備中です。原文の説明を表示しています。

Dragoon0x/taste-skills62026年2月27日 更新

Helps detection engineers identify coverage blind spots in system command execution detection rules, evaluate bypass risks, and reduce false negatives. Strictly limited to system command execution rules; not applicable to browser credential theft or abnormal process creation without command semantics.

日本語の概要は準備中です。原文の説明を表示しています。

DetectEng-SOCLabs/detection-rule-bypass-analyzer62026年4月8日 更新

Tests APIs for Broken Function Level Authorization (BFLA) vulnerabilities where regular users can invoke administrative functions or access privileged API endpoints by directly calling them. The tester identifies admin and privileged endpoints, then attempts to access them with regular user credentials by manipulating HTTP methods, URL paths, and request parameters. Maps to OWASP API5:2023 Broken Function Level Authorization. Activates for requests involving BFLA testing, admin endpoint bypas...

日本語の概要は準備中です。原文の説明を表示しています。

MustafaKemal0146/fetih52026年10月11日 更新

Web uygulamalarında JWT bypass — alg:none, CVE-2022-39227, SSRF zinciri

日本語の概要は準備中です。原文の説明を表示しています。

MustafaKemal0146/fetih52026年10月11日 更新

Z3 SMT solver ile CTF constraint çözme — byte equations, hash collision, validator bypass

日本語の概要は準備中です。原文の説明を表示しています。

MustafaKemal0146/fetih52026年10月11日 更新

Busabase-backed family-office App-in-Skill that consolidates multi-entity investment holdings into one read-only dashboard. Use when the user invokes $kelly-family-office or /kelly-family-office, wants a consolidated family office view, multi-entity aggregation across an individual, trust, company, fund, or foundation, total AUM in a base currency, asset allocation by asset class, by entity/member, or by custodian/institution, multi-currency FX consolidation, CSV import of holdings, unrealized P/L, or read-only portfolio monitoring. It reads Busabase only and NEVER moves money or trades.

日本語の概要は準備中です。原文の説明を表示しています。

mr-kelly/skills52026年10月14日 更新

Resolves a PostHog experiment reference from natural language to a concrete experiment ID by browsing `experiment-list` (not feature-flag tools), with disambiguation when multiple experiments match. Use when the user names or quotes an experiment ("split test demo", "the File engagement boost experiment", "onboarding retention test", "landing page hero experiment", "pricing experiment"), describes it loosely ("the signup experiment", "my pricing test", "the one with the new checkout"), uses a relative reference ("latest", "most recent", "the one I created yesterday"), filters by status (running, draft, stopped, archived), or otherwise refers to an experiment by anything other than its concrete ID.

日本語の概要は準備中です。原文の説明を表示しています。

0xAidan/polymarket-bot-test42026年9月4日 更新

Authors bioinformatics pipelines in WDL (Workflow Description Language) run by Cromwell or miniwdl, targeting the GATK/Broad and Terra/AnVIL/BioData Catalyst cloud ecosystem, with tasks, workflows, scatter-gather parallelism, structs, and a runtime block that sizes the cloud VM. Use when deciding to target Terra/AnVIL/GATK/WARP (chosen for the ecosystem, not the language); sizing runtime disks dynamically for a fresh-per-task cloud VM (ceil(size(f)*factor)+buffer); choosing preemptible vs on-demand VMs by task length and idempotency; picking Cromwell (production, cloud, call-caching) vs miniwdl (local dev, miniwdl check linting, readable errors); enabling and debugging call-caching silent-miss modes; pinning Docker by digest for reproducibility and cache stability; or scattering an array for parallel fan-out.

日本語の概要は準備中です。原文の説明を表示しています。

huang-sh/DeepScience42026年7月15日 更新

aeo

無料

Answer Engine Optimization (AEO) skill — optimize content to be cited by AI language models (ChatGPT, Perplexity, Claude, Gemini, Mistral) as authoritative sources. Distinct from SEO — AEO optimizes for citation in LLM-generated responses, not search rankings. Use when planning content for AI-first search audiences, auditing existing content for E-E-A-T signals, tracking which pages get cited by which LLMs, or building a citation-friendly content strategy. Triggers — 'AEO audit', 'optimize for ChatGPT', 'get cited by Perplexity', 'LLM citation strategy', 'answer engine optimization', 'content for AI search', 'E-E-A-T audit'. Output is a markdown audit report (default) or JSON for pipeline integration. Stdlib-only Python tools.

日本語の概要は準備中です。原文の説明を表示しています。

aibot88/sec_skill_store42026年5月27日 更新

Apply the aoa-safe-infra-change workflow inside an abyss-* repository using repo-relative operational surfaces, explicit local authority notes, rollback posture, and local validation commands. Use when the base infra-change workflow is correct but a thin project overlay is needed for one abyss repo. Do not use when the base skill is sufficient without local adaptation or when the task is really about producing a shareable artifact.

日本語の概要は準備中です。原文の説明を表示しています。

aibot88/sec_skill_store42026年5月27日 更新

Check, from the employer's side, what has been put in writing before a paid Otameshi Tenshoku assignment starts under gyomu-itaku: item by item whether the deliverable, delivery date, fee and how it is calculated, payment due date, who pays, out-of-scope work, revision limits, company support, rights, confidentiality and termination are stated in a contract, purchase order or email rather than in chat or by word of mouth, count the days from delivery to payment, and find pay tied to satisfaction or hiring, unpaid or unlimited revisions and one-sided termination. Use when a hiring manager, recruiter or small-business owner is about to offer terms to a candidate, has been asked by a candidate what is still unwritten, or needs the conditions written for a platform contract screen; do not use to judge whether the terms are lawful or the fee fair, to compute withholding or consumption tax, for employment contracts, or to sign, send or conclude the contract on the user's behalf.

日本語の概要は準備中です。原文の説明を表示しています。

ficilcom/otame4-work-skills42026年9月23日 更新