「library」の検索結果

Assesses RNA-seq data quality specifically for alternative splicing analysis. QC layers include experimental design audit (library prep, read length, depth, replicates), STAR 2-pass cohort-style alignment, junction saturation curves and discovery plateau detection, novel-vs-known junction ratio diagnostics, junction-overhang distribution, splice-site strength scoring (MaxEntScan intrinsic + SpliceAI context-aware), strandedness verification, GENCODE basic vs comprehensive choice, and rRNA contamination screening. Splicing analysis is more demanding than DGE on read length, depth, library prep, alignment strategy, and annotation choice — failures silently bias PSI estimates and inflate novel-junction false positives. Use when evaluating data suitability for splicing analysis, troubleshooting low event detection, or designing sequencing experiments where AS is a primary endpoint.

日本語の概要は準備中です。原文の説明を表示しています。

Generate and run tests for Adobe App Builder actions and UI components. Scaffolds Jest unit tests, integration tests against deployed actions, contract tests for Adobe API interactions, and React component tests using Testing Library. Provides mock helpers for State, Files, Events SDKs, @adobe/aio-lib-* clients, ExC Shell context (@adobe/exc-app), and UIX Guest SDK (@adobe/uix-guest). Use this skill whenever the user mentions testing App Builder actions, writing unit tests for Runtime actions, creating integration tests, mocking Adobe SDKs, setting up test fixtures, running aio app test, or wants to verify action behavior before deployment. Also trigger when users mention Jest configuration for App Builder, test coverage, CI test setup, React component test, Testing Library, UI test, Provider wrapper, test my page, test my form, test my table, test my component, mock shell context, mock extension context, debug test failures, or fix Jest errors.

日本語の概要は準備中です。原文の説明を表示しています。

Detect and resolve naming collisions, overlapping intent triggers, and insufficient intent diversity across the skill library. Load when a new skill is created (called by universal-skill-creator), during improvement passes (called by improve-skills), or when the user asks to deconflict skills, check for naming collisions, audit trigger overlap, review intent coverage, find duplicate triggers, check skill names, or says "are any skills too similar", "which skills overlap", "deconflict the library", "check for confusing skill names", "intent audit".

日本語の概要は準備中です。原文の説明を表示しています。

Run a fast, read-only health check across all skills in the library and produce a structured quality report — without modifying anything. Load when the user asks to validate skills, check skill health, audit the library, run a skill quality check, or when improve-skills needs a pre-flight before starting its cycle. Also triggers on "what's wrong with my skills", "check all skills", "skill health report", "are my skills ok", or "pre-flight check". Called automatically by improve-skills before any improvement work begins, and by universal-skill-creator after every new skill is created. Never modifies any file — only reads and reports.

日本語の概要は準備中です。原文の説明を表示しています。

Automatically maintain skill library consistency whenever a structural change occurs — new skill added, skill renamed, skill deprecated, call graph rewired, or category changed. Updates SKILL-INDEX.md, AGENTS.md, README.md, skill graph, docs/prd/PRD.md, and docs/architecture.md. Load when universal-skill-creator finishes creating a skill, split-skill extracts a child, deprecate-skill retires a skill, improve-skills makes a structural change, or the user manually renames or restructures skills. Also triggers on "update the skill index", "sync skill references", "refresh the skill graph", "fix broken skill cross-references", or "update docs after skill change".

日本語の概要は準備中です。原文の説明を表示しています。

Audit, improve, and compress every skill in the repo using live research. Load when the user asks to improve skills, audit the skill library, upgrade existing skills, refresh with new research, do a skill health check, or says "improve all skills", "update the skill library", "skill audit", or "run an improvement pass". Applies live domain research, fixes structural gaps, checks for skill linking opportunities, then rewrites and resizes each skill. Supports TARGETED mode (`TARGET=<skill> [SKIP_RESEARCH=true]`) for single-skill fixes, including learn-from-chat restructure escalations. All skills are in scope including meta skills.

日本語の概要は準備中です。原文の説明を表示しています。

Guided first-run that produces a real verified win in under five minutes using the skill library on a seeded offline fixture. Load when a new user asks how to start, run the demo, try agent-loom, or get a quick win. Also triggers on "quickstart", "first run", "demo agent-loom", "try the skills", or onboarding to the library. Zero external credentials required. Idempotent — safe to run multiple times.

日本語の概要は準備中です。原文の説明を表示しています。

Generate user-facing or internal release notes and changelogs. Load when the user prepares a release, tags a version, or wants to summarize recent progress. Also triggers on "write a changelog", "prepare release notes", "what's new in this version", "summarize my commits", or "create a release summary". Auto-triggered by library-skill after major repo changes (new skills added, skills renamed, structure changes). Applicable to any project, including this skill library itself.

日本語の概要は準備中です。原文の説明を表示しています。

Calls significant loops from protein-directed and targeted 3C assays (HiChIP, PLAC-seq, Capture Hi-C/PCHi-C, ChIA-PET) where the contact background is peak-anchored and coverage-biased, so generic Hi-C loop callers (cooltools dots, Juicer HiCCUPS) use the wrong null. Covers FitHiChIP (config-driven coverage+distance-decay spline regression, peak-to-peak vs peak-to-all foreground, loose vs stringent background, coverage vs ICE bias), MAPS (positive Poisson regression on bias factors for PLAC-seq/HiChIP), hichipper (restriction-site-distance bias model + library QC), CHiCAGO (Delaporte two-component Brownian+technical background for asymmetric bait x other-end Capture Hi-C), the with/without separate-ChIP anchor decision, and differential loops via diffloop. Use when calling loops from HiChIP/PLAC-seq/Capture Hi-C, choosing FitHiChIP/MAPS/CHiCAGO, picking peak-to-all vs peak-to-peak, setting the loop FDR, supplying ChIP peaks as anchors, QCing a HiChIP library, or comparing loops between conditions.

日本語の概要は準備中です。原文の説明を表示しています。

Designs and analyzes pooled prime-editor (PE) screens for installing precise genetic variants without bystander confounding. Covers pegRNA design with PRIDICT and PRIDICT2 (Mathis 2023/2024) for predicting per-pegRNA editing efficiency, pegRNA architecture (spacer + scaffold + PBS + RTT), PE2 / PE3 / PE3b / PEmax / PEAR variants, MOSAIC in situ saturation mutagenesis (Hsu JY et al 2024 bioRxiv), the PRIME pooled-screen methodology (Erwood/Doman 2023 Nat Biotechnol 41:885; ~3,699 ClinVar variant screens), chromatin context as a primary determinant of PE efficiency, scaffold-incorporation and indel byproduct quantification with CRISPResso2, and the cross-modal validation strategy of PE + base-editor screens for variant function. Use when designing a pegRNA library for variant installation, choosing between BE and PE for a specific edit, predicting pegRNA efficiency before library synthesis, analyzing PE screen output, distinguishing intended-edit from scaffold-incorporation, or scaling PE screens to thousands of variants.

日本語の概要は準備中です。原文の説明を表示しています。

Quality control for pooled CRISPR screens covering library representation, Gini index, log-skew, replicate Pearson and Spearman concordance, essentialome precision-recall AUC against CEGv2 (Hart 2017), Cas9 cut-toxicity diagnostics, copy-number amplicon detection (Aguirre 2016 / Munoz 2016), bottleneck propagation through plasmid pool, infection, selection, and endpoint stages, MOI verification, and DepMap-style screen-quality scoring. Use when assessing screen quality before hit calling, deciding whether to repeat or rescue a screen, diagnosing low-confidence hits, choosing between MAGeCK / BAGEL2 / Chronos based on quality grade, picking a normalization strategy from QC signatures, or evaluating whether an in-vivo screen retained adequate library complexity.

日本語の概要は準備中です。原文の説明を表示しています。

Assesses ChIP-seq quality across antibody specificity, fragmentation, enrichment, replicate concordance, and library complexity. Computes FRiP, NSC/RSC (phantompeakqualtools), library complexity (NRF/PBC1/PBC2), deepTools plotFingerprint (JS distance, AUC, synthetic JS), ChIPQC, IDR with ENCODE Nself/Nt rules, and detects hyper-ChIPable artifacts. Use when validating an antibody, diagnosing failed peak calls, deciding whether to proceed with downstream analysis, grading against ENCODE thresholds, or auditing replicate concordance.

日本語の概要は準備中です。原文の説明を表示しています。

Assesses RNA-seq data quality specifically for alternative splicing analysis. QC layers include experimental design audit (library prep, read length, depth, replicates), STAR 2-pass cohort-style alignment, junction saturation curves and discovery plateau detection, novel-vs-known junction ratio diagnostics, junction-overhang distribution, splice-site strength scoring (MaxEntScan intrinsic + SpliceAI context-aware), strandedness verification, GENCODE basic vs comprehensive choice, and rRNA contamination screening. Splicing analysis is more demanding than DGE on read length, depth, library prep, alignment strategy, and annotation choice — failures silently bias PSI estimates and inflate novel-junction false positives. Use when evaluating data suitability for splicing analysis, troubleshooting low event detection, or designing sequencing experiments where AS is a primary endpoint.

日本語の概要は準備中です。原文の説明を表示しています。

Curated design reference library for Maxim design work — typography scales, color systems, component patterns, spacing and layout references. Consulted by the other design skills rather than invoked directly.

日本語の概要は準備中です。原文の説明を表示しています。

Guide for using the Microsoft Fluent UI Blazor component library (Microsoft.FluentUI.AspNetCore.Components NuGet package) in Blazor applications. Use this when the user is building a Blazor app with Fluent UI components, setting up the library, using FluentUI components like FluentButton, FluentDataGrid, FluentDialog, FluentToast, FluentNavMenu, FluentTextField, FluentSelect, FluentAutocomplete, FluentDesignTheme, or any component prefixed with "Fluent". Also use when troubleshooting missing providers, JS interop issues, or theming.

日本語の概要は準備中です。原文の説明を表示しています。

Skill for prompt-template-library tasks.

日本語の概要は準備中です。原文の説明を表示しています。

Maintains library compatibility. Binary/source compat rules, type forwarders, SemVer impact.

日本語の概要は準備中です。原文の説明を表示しています。

Extract and catalog attack patterns from cyber threat intelligence reports into a structured STIX-based library mapped to MITRE ATT&CK for detection engineering and threat-informed defense.

日本語の概要は準備中です。原文の説明を表示しています。

Generate and run tests for Adobe App Builder actions and UI components. Scaffolds Jest unit tests, integration tests against deployed actions, contract tests for Adobe API interactions, and React component tests using Testing Library. Provides mock helpers for State, Files, Events SDKs, @adobe/aio-lib-* clients, ExC Shell context (@adobe/exc-app), and UIX Guest SDK (@adobe/uix-guest). Use this skill whenever the user mentions testing App Builder actions, writing unit tests for Runtime actions, creating integration tests, mocking Adobe SDKs, setting up test fixtures, running aio app test, or wants to verify action behavior before deployment. Also trigger when users mention Jest configuration for App Builder, test coverage, CI test setup, React component test, Testing Library, UI test, Provider wrapper, test my page, test my form, test my table, test my component, mock shell context, mock extension context, debug test failures, or fix Jest errors.

日本語の概要は準備中です。原文の説明を表示しています。

Pick the right library for a given frontend task from a curated, opinionated list — numbers, OTP inputs, charts, command menus, virtualization, drag and drop, toasts, state, styling, and more. Only runs when explicitly invoked; it does not trigger on its own.

日本語の概要は準備中です。原文の説明を表示しています。

Comprehensive Linux privilege escalation methodology for offensive security engagements. Covers the full attack surface from a low-privilege shell to root: SUID/SGID binary abuse via GTFOBins, Linux capabilities exploitation (cap_setuid, cap_dac_override, cap_dac_read_search), sudo misconfigurations including NOPASSWD rules and Baron Samedit (CVE-2021-3156), cron job abuse through writable scripts, PATH hijacking, and wildcard injection with tar/rsync/chown. Includes writable /etc/passwd attacks, NFS no_root_squash exploitation, kernel exploits (DirtyPipe CVE-2022-0847, DirtyCow CVE-2016-5195, PwnKit CVE-2021-4034), Docker group container escapes, LD_PRELOAD and LD_LIBRARY_PATH hijacking for shared library injection, systemd service misconfigurations, and sensitive file enumeration for credential harvesting. Integrates automated enumeration with LinPEAS, linux-exploit-suggester, pspy for process monitoring, and GTFOBins for binary exploitation. Each technique includes detection signatures and defender-sid...

日本語の概要は準備中です。原文の説明を表示しています。

Core component library and design system patterns. Use when building UI, using design tokens, or working with the component library.

日本語の概要は準備中です。原文の説明を表示しています。

FIPA standard library of agent interaction protocols for structured multi-agent communication

日本語の概要は準備中です。原文の説明を表示しています。

複数の画面デザイン画像をVue 3のページや共通部品に一括変換します。VantなどのUIライブラリへの対応付けや、画面遷移の初期コード作成も扱います。

• デザイン画像をVue 3に変換したいとき
• 一覧や読み込み中の画面をまとめたいとき
• 繰り返す画面領域を共通化したいとき