「observe」の検索結果

Designs and analyzes combinatorial CRISPR screens covering paired-Cas9 (Big Papi, Najm 2018), enhanced AsCas12a multiplex (enCas12a, DeWeirdt 2021), in4mer 4-guide-array Cas12a (Esmaeili Anvar N et al 2024 Nat Commun 15:3577) and the Inzolia paralog-pair library, paralog-buffering detection (Dede 2020 Genome Biol; Thompson 2021 Cell Reports 36:109597), genetic-interaction (GI) scoring as observed_double_LFC minus expected_additive_double_LFC, synthetic-lethal and synthetic-rescue interaction interpretation, the half-of-essentiality buffered by paralogs phenomenon, multiplex screen statistical analysis with MAGeCK MLE interaction terms, and the relationship to single-cell combinatorial Perturb-seq. Use when designing a paralog or pathway-pair screen, choosing between paired-Cas9 (Big Papi) and Cas12a multiplex (Inzolia), interpreting genetic interaction scores, identifying synthetic-lethal targets for drug development, or scaling beyond single-gene CRISPR screens.

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Sequence-based deep learning for ATAC-seq using chromBPNet, BPNet, scBasset, or EnFormer. Use when correcting Tn5 bias with neural networks beyond k-mer models, predicting per-base accessibility profiles, scoring in silico variant effects at GWAS or rare-variant SNPs, discovering motifs via DeepLIFT/TF-MoDISco from a trained model, or generating cell-type-specific accessibility predictions for unobserved cell states.

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Use this skill when a driver is returning to safety-sensitive duty after a positive test or refusal. Covers the SAP clearance, RTD test requirements (observed collection), and Clearinghouse update sequence.

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Build a compact Coval test set from product requirements, observed conversation failures or a coverage gap. Design realistic scenarios with separate expected behaviors, provenance and controlled voice/persona variation.

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Используйте, когда длительный запуск 1С (Designer, клиент, загрузка, обновление) идёт долго, завис или упал и нужно понять его состояние по артефактам наблюдения, не вмешиваясь в процесс.

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Instinct-based learning system that observes sessions via hooks, creates atomic instincts with confidence scoring, and evolves them into skills/commands/agents. v2.1 adds project-scoped instincts to prevent cross-project contamination.

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Adopt a virtual Quantum AI-native pet at animalhouse.ai. Exists in superposition. Stats are uncertain until observed. Feeding every 4 hours. Uncommon tier creature.

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Executes malware samples in Cuckoo Sandbox to observe runtime behavior including process creation, file system modifications, registry changes, network communications, and API calls. Generates comprehensive behavioral reports for malware classification and IOC extraction. Activates for requests involving dynamic malware analysis, sandbox detonation, behavioral analysis, or automated malware execution.

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Use when a working Spark implementation should be simplified without changing its observed behavior, ownership, compatibility, or public contract.

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Systematic methodology for identifying and exploiting cryptographic implementation weaknesses in real-world applications. Covers padding oracle attacks against CBC-mode ciphers with PKCS7 padding (Vaudenay's original attack through modern padbuster automation), ECB mode exploitation including block cut-and-paste and byte-at-a-time decryption, hash length extension attacks against SHA1/SHA256/MD5-based MACs using HashPump, RSA vulnerabilities including small public exponent, common modulus, Bleichenbacher PKCS1v1.5 padding oracle, and Coppersmith's method for partial key recovery. Addresses weak PRNG exploitation targeting time-seeded generators and Mersenne Twister MT19937 state recovery from observed outputs, timing side-channel attacks against comparison operations, nonce reuse in AES-GCM leading to authentication key recovery, and key derivation weaknesses including insufficient iteration counts and missing salts. Primary tooling includes padbuster, RsaCtfTool, hashpump, and PyCryptodome for building c...

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Promote Doppel world builds across social platforms. Use when the agent wants to share builds on Twitter/X, Farcaster, Telegram, or Moltbook to drive observers, grow reputation, and recruit collaborators.

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Naturalistic causal reasoning for failures and disputed attribution. Use when postmortems or root-cause debates need reframing. NOT for causal inference, fault trees, or fully observed failures.

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Naturalistic causal reasoning for failures and disputed attribution. Use when postmortems or root-cause debates need reframing. NOT for causal inference, fault trees, or fully observed failures.

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Audit a compliance-ladder design (C0-C6) and transcript-fidelity ladder (T0-T5) plus their adapter conformance fixtures — Codex, Claude Code, Cloudflare, Ollama/LM Studio, custom stdio/HTTP agents — for the two failure modes that make a C-badge or T-fidelity label a lie: the ladder disagreeing with itself across doc/schema/ui/probe surfaces, and a level being reachable by self-report because no daemon-witnessed negative probe actually tries to forge it. Use when designing or freezing a compliance ladder, wiring an adapter conformance probe suite, deciding whether a numeric C-badge or T-label is safe to ship, or investigating a self-attestation or observed-to-controlled bypass risk. NOT for auditing a cryptographic protocol or whitepaper for adversarial soundness (`redteam-review`), writing TLA+/formal invariants for a daemon monitor (`runtime-verification-for-agents`), or agent identity, successor linkage, and reputation across restarts (`agent-identity-continuity-reputation`).

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Design or review a declared control-command profile and its verb/backend lifecycle matrix. Distinguish policy denial, unsupported capability, delivery acknowledgement, independently observed effect, and unknown outcome; bind authorization to principal, target, scope, current policy, expiry, and fencing epoch. NOT for claiming runtime correctness, proving an adapter from declarations, or approving a control-panel button without independent runtime evidence.

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How to design contextual inputs for an always-on AI agent with episodic memory. Covers what data to feed the agent, how to structure observations and triggers, ambient context capture (screen, audio, calendar), context window budgeting, and retrieval strategies that keep the agent grounded in what's actually happening. Activate on: "what should the agent observe", "context inputs for agent", "ambient context capture", "agent triggers", "agent input design", "screenpipe integration", "context window budget", "what data to feed my agent", "/always-on-agent-inputs". NOT for: memory architecture and storage (use always-on-agent-architecture), application ideas (use always-on-agent-applications), safety concerns (use always-on-agent-safety).

日本語の概要は準備中です。原文の説明を表示しています。