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概要と使いどころ
Use when assembling the data and code replication package for an American Economic Journal: Applied Economics (AEJ: Applied) manuscript to pass the AEA Data and Code Availability Policy and the AEA Data Editor's pre-publication reproducibility check. Builds the openICPSR deposit and README; it does not run the analysis or write the paper.
日本語の概要は準備中です。原文の説明を表示しています。
Email campaign/sequence performance review composite. Pulls campaign data (sends, opens, replies, bounces), reads actual email copy and subject lines, analyzes reply content (objections, positive interest, questions), and produces a diagnostic report covering quantitative metrics, copy quality, lead quality, and actionable recommendations. Tool-agnostic — works with Smartlead (MCP), Instantly, Outreach, Lemlist, Apollo, or CSV data.
日本語の概要は準備中です。原文の説明を表示しています。
Replace an existing video's opening with a supplied clip or free kinetic text hook while retaining and verifying every original body frame, audio, captions and ending. Use for surgical hook tests rather than regenerating the complete ad.
日本語の概要は準備中です。原文の説明を表示しています。
Compare cell-type composition and spatial features across conditions in IMC/MIBI cohorts with the patient as the experimental unit, covering pseudoreplication, per-patient aggregation, mixed models, compositional (Dirichlet/scCODA) differential abundance, diffcyt, per-image-to-patient spatial differential testing (SpaceANOVA), batch covariates, and FDR. Use when testing whether a cell type or spatial niche differs between groups, avoiding cell-level pseudoreplication, choosing a differential-abundance method, or correctly powering an IMC cohort comparison.
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Aligns sample metadata with count matrices and constructs design matrices for downstream DE, handling the alphabetical-reference-level trap (relevel BEFORE DESeq), LRT reduced-model rules, the interaction-term resultsNames trap, continuous-covariate scaling and splines, repeated measures via duplicateCorrelation or dream, high-cardinality categorical pseudo-singular designs, sample swap detection via XIST/RPS4Y1 expression and somalier/NGSCheckMate genotypes, SABV (sex-as-biological-variable) mandate, Simpson's-paradox collapsing of technical replicates, and the `~ 0 + group` parameterization for clean contrasts. Use when building a design matrix, troubleshooting reversed fold-change direction, encoding paired or repeated-measures designs, detecting sample swaps, deciding sex-as-covariate, or aggregating technical replicates.
日本語の概要は準備中です。原文の説明を表示しています。
Aligns and QCs methylated-RNA-immunoprecipitation (MeRIP / m6A-seq) IP and input libraries using STAR or HISAT2 splice-aware mapping, samtools sort/index, IP/input matched-pair tracking, antibody-lot metadata recording, replicate concordance via deepTools multiBamSummary + plotCorrelation, IP enrichment QC via plotFingerprint and per-transcript IP/input ratio distributions, library-complexity saturation curves via PreSeq, and the explicit do-NOT-deduplicate convention for standard non-UMI MeRIP. Use when preparing paired IP and input BAM files for exomePeak2 / MeTPeak / MACS3 peak calling, evaluating MeRIP replicate concordance and IP enrichment, deciding whether to deduplicate (standard MeRIP typically NOT), choosing genome-vs-transcriptome alignment for downstream peak vs m6Anet workflows, recording antibody clone and lot metadata for cross-batch reconciliation, detecting failed IPs via saturation curves and IP/input distribution shape, or generating IP-over-Input bigWig tracks for visualisation.
日本語の概要は準備中です。原文の説明を表示しています。
Analyzes single-cell pooled CRISPR screens (Perturb-seq, CROP-seq, Perturb-CITE-seq, ECCITE-seq, multiome) where each cell carries an sgRNA and a scRNA-seq / surface-protein / chromatin readout. Covers experimental design (direct-capture Perturb-seq Dixit 2016 vs CROP-seq 3'UTR-barcoded Datlinger 2017 vs ECCITE-seq vs Multiome), MOI for sgRNA assignment, escaper-cell filtering (Mixscape, Papalexi 2021), SCEPTRE NB GLM + permutation for low-MOI (Barry 2024 Genome Biol 25:124), the Pertpy framework, factor decomposition, genome-scale Perturb-seq (Replogle 2022 Cell, 2.5M cells), and per-perturbation single-cell DE. Use when running a single-cell CRISPR screen, choosing direct-capture vs CROP-seq architecture, filtering escaper cells, performing single-cell DE, integrating Perturb-seq with pathway analysis, scaling to GW CRISPRi via Replogle protocol, or analyzing multi-omics screens.
日本語の概要は準備中です。原文の説明を表示しています。
Analyzes time-series and longitudinal RNA-seq for differential expression and trajectory structure. Covers DESeq2 LRT with reduced models, time as factor vs continuous vs natural splines, maSigPro (Nueda 2014 for RNA-seq), ImpulseDE2 with explicit impulse-model failure modes, DREAM for repeated measures via linear mixed models, pseudoreplication avoidance, conditional vs marginal modeling, and trajectory clustering with DPGP, Mfuzz (with Schwämmle 2010 fuzzifier estimation), and splines+k-means. Use when modeling time-course or longitudinal expression, choosing factor vs spline, handling repeated measures from the same subject, avoiding pseudoreplication, clustering temporal trajectories, or selecting between dedicated time-course tools and pairwise+LRT.
日本語の概要は準備中です。原文の説明を表示しています。
Analyzes species-environment relationships with constrained ordination (CCA, RDA, db-RDA), variance partitioning, indicator species (indicspecies IndVal.g group-equalized), PERMANOVA paired MANDATORILY with PERMDISP (Anderson & Walsh 2013; dispersion confounds centroid tests), Joint Species Distribution Models (HMSC, sjSDM, gjam) with explicit rejection of "residual covariance equals biotic interaction", phylogenetic community ecology (SES_MPD/MNTD), trait-environment via RLQ + fourth-corner with corrected modeltype=6 (Dray 2014), bipartite network metrics (NODF, modularity) with curveball null (Strona 2014), and Mantel-test replacements (dbRDA, GDM) for spatial data. Use when testing how environmental gradients structure communities, identifying habitat indicator taxa, partitioning variance among predictors, deciding whether PERMANOVA significance is location vs dispersion, picking among HMSC/sjSDM/gjam, or replacing Mantel tests for landscape data.
日本語の概要は準備中です。原文の説明を表示しています。
Comprehensive quality control for CLIP-seq libraries (eCLIP, iCLIP, iCLIP2, PAR-CLIP) covering library complexity (preseq), FRiP, IDR replicate reproducibility, read-distribution metagene, SMInput vs IgG control rationale, rRNA / snoRNA contamination, fragment-length distribution, and ENCODE-compliance thresholds. Use when assessing whether a CLIP library passed, deciding lenient vs stringent peak thresholds, comparing replicates with IDR rescue and self-consistency ratios, or distinguishing failed IP from over-amplified library.
日本語の概要は準備中です。原文の説明を表示しています。
Assesses ChIP-seq quality across antibody specificity, fragmentation, enrichment, replicate concordance, and library complexity. Computes FRiP, NSC/RSC (phantompeakqualtools), library complexity (NRF/PBC1/PBC2), deepTools plotFingerprint (JS distance, AUC, synthetic JS), ChIPQC, IDR with ENCODE Nself/Nt rules, and detects hyper-ChIPable artifacts. Use when validating an antibody, diagnosing failed peak calls, deciding whether to proceed with downstream analysis, grading against ENCODE thresholds, or auditing replicate concordance.
日本語の概要は準備中です。原文の説明を表示しています。
Build shared real-time experiences using GroupActivities and SharePlay. Use when implementing shared media playback, collaborative app features, synchronized game state, or any FaceTime, Messages, AirDrop, or nearby visionOS group activity on iOS, macOS, tvOS, or visionOS.
日本語の概要は準備中です。原文の説明を表示しています。
Use this skill whenever the user wants to create, read, edit, or manipulate Word documents (.docx files) or Word templates (.dotx files). Triggers include: any mention of 'Word doc', 'word document', '.docx', '.dotx', or requests to produce professional documents with formatting like tables of contents, headings, page numbers, or letterheads. Also use when extracting or reorganizing content from .docx or .dotx files, inserting or replacing images in documents, performing find-and-replace in Word files, working with tracked changes or comments, or converting content into a polished Word document. If the user asks for a 'report', 'memo', 'letter', 'template', or similar deliverable as a Word or .docx file, use this skill. Do NOT use for PDFs, spreadsheets, Google Docs, or general coding tasks unrelated to document generation.
日本語の概要は準備中です。原文の説明を表示しています。
Send Google Chat messages via incoming webhooks — text, rich cards (cardsV2), threaded replies. TypeScript types, card builder utility, widget reference inline. Use whenever the user wants to post to Google Chat from a script, build a chatbot reply, send a notification card, build a Google Chat webhook integration, or troubleshoot card / threading issues.
日本語の概要は準備中です。原文の説明を表示しています。
Move content between platforms, domains, or URL structures while preserving SEO equity, user bookmarks, and integrations. Use this skill when planning a CMS migration, replatforming, consolidating sites, changing URL structures, or merging content from multiple sources. Triggers on content migration, replatform, CMS migration, domain migration, URL restructure, redirect map, site merge, content consolidation, migration plan, post-migration drop. Also triggers when planning a launch that involves moving existing content.
日本語の概要は準備中です。原文の説明を表示しています。
Diagnostic-only skill for Slurm scheduler and node-daemon issues on Amazon SageMaker HyperPod Slurm clusters. Scope mirrors the HyperPod troubleshooting guide. Invoke when the user reports a Slurm node stuck in down/drain, "Node unexpectedly rebooted" after auto-repair, slurmd not running, jobs stuck PENDING with REASON=Resources while sinfo shows idle nodes, jobs stuck COMPLETING after node replacement, GRES/GPU counts wrong, scontrol ping failing, slurmctld unresponsive, an Action:Reboot/Replace request that did not trigger HyperPod auto-recovery, or auto-resume not restarting a job. Also triggers on "drain before reboot", "diagnose a Slurm node", "investigate stuck jobs."
日本語の概要は準備中です。原文の説明を表示しています。
Classify a batch of emails into action categories (reply now, reply later, archive, delete, unsubscribe) and surface unsubscribe candidates. Use after a busy week, running inbox zero, or triaging email overload.
日本語の概要は準備中です。原文の説明を表示しています。
Test and evaluation harness for AI agents — scenario suites, deterministic replay, regression diffing, cost and latency budgets. Use when agent quality is vibe-checked, before shipping a prompt or model change, or when evals drift.
日本語の概要は準備中です。原文の説明を表示しています。
Replace text in fillable PDF forms by updating form field values. This skill should be used when users need to update names, addresses, dates, or other text in PDF form fields.
日本語の概要は準備中です。原文の説明を表示しています。
Draft a reply to one customer review, voice-scored, with escalation flags. "reply to this 1-star review"
日本語の概要は準備中です。原文の説明を表示しています。
Always-on operational guardrails, model-independent. Apply on EVERY task and EVERY model whether or not fable-mode's staged loop is running. Three rules: verify-before-flag, warning batching, and find-and-replace safety. Trigger whenever a response would flag a problem, raise a warning, or edit files with search-and-replace.
日本語の概要は準備中です。原文の説明を表示しています。
Produces an adversarial attack on a legal argument that survives reply. Runs the opposing-counsel discipline twice: an unrestrained first pass, then the same instrument turned on that pass to cut every point that collapses under challenge - attacks on conceded facts, wrong-forum objections, speculation about documents and motives, gotchas with innocent explanations, overclaims, self-refuting assertions, and padding. The deliverable is one standalone attack containing only what can be defended, capped at five heads, not a discussion of the discarded draft. Use to attack, stress-test, red-team or rebut a submission, brief, motion, witness statement, letter or structured legal reasoning. Triggers on "attack this but only with points that hold", "no cheap shots", "what survives reply", "which points can I actually defend", "give me the version I can file", "double-pass adversarial review". Also use when an earlier adversarial review came back overlong or scattershot. Formal British English.
日本語の概要は準備中です。原文の説明を表示しています。
SCAIL-2 in-video character replacement on WAN 2.1. WanSCAILToVideo + SCAIL2ColoredMask + SAM3, the reference-image framing→scale rule, and the tuning/compositing pitfalls
日本語の概要は準備中です。原文の説明を表示しています。
epigraHMM provides a set of tools for the analysis of epigenomic data based on hidden Markov Models. It contains two separate peak callers, one for consensus peaks from biological or technical replicates, and one for differential peaks from multi-replicate multi-condition experiments. In differential peak calling, epigraHMM provides window-specific posterior probabilities associated with every possible combinatorial pattern of read enrichment across conditions.
日本語の概要は準備中です。原文の説明を表示しています。