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概要と使いどころ
Provider-independent production design direction for AI-generated media. Use when translating narrative, brand, advertising, product, social, film, or worldbuilding intent into sets, locations, props, color and material palettes, era research, graphic and environmental design, continuity bibles, image/video prompt planning, reference strategy, production constraints, iteration notes, handoff specs, and QA.
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Predict B-cell and T-cell epitopes using BepiPred, IEDB tools, and structure-based methods for vaccine and antibody design. Identify immunogenic regions in antigens. Use when designing vaccines, mapping antibody binding sites, or predicting immunogenic peptides.
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Search NCBI databases using Biopython Bio.Entrez (ESearch, EInfo, EGQuery, ESpell). Use when finding records by keyword, building reproducible field-qualified queries, navigating the Entrez Query Translator, exploiting the history server for large result sets, handling retmax caps, or interpreting weekly index lag. Covers PubMed, Nucleotide, Protein, Gene, SRA, GEO, Assembly, Taxonomy, ClinVar, dbSNP.
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Detect contamination and assess genome quality using CheckM, CheckM2, GTDB-Tk, and GUNC for metagenome-assembled genomes and isolate assemblies. Use when checking assemblies for contamination.
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Detect and remove doublets (multiple cells captured in one droplet) from single-cell RNA-seq data. Uses Scrublet (Python), DoubletFinder (R), and scDblFinder (R). Essential QC step before clustering to avoid artificial cell populations. Use when identifying and removing doublets from scRNA-seq data.
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Analyzes community composition using constrained ordination (CCA, RDA, db-RDA), variance partitioning (varpart), indicator species analysis (indicspecies multipatt), and distance-based environmental gradient methods with vegan. Links species composition to environmental explanatory variables. Use when testing how environmental gradients structure species communities, identifying habitat indicator taxa, or partitioning explained variation among predictors. Not for basic unconstrained ordination and PERMANOVA (see microbiome/diversity-analysis).
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Pull pre-computed ortholog calls from public databases (OrthoDB, Ensembl Compara, OMA browser, eggNOG, PANTHER, KEGG Orthology, HomoloGene) via their REST APIs. Use when orthologs are already curated upstream, when the question is "what is the X ortholog of Y" rather than "how to infer orthology de novo", when batch-mapping gene IDs across species, or when comparing the resources for consensus calls. Encodes confidence-level semantics, 1:1 vs 1:many vs many:many, HomoloGene deprecation, and when to defect to de novo computation.
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Identify direct miRNA-target interactions from AGO HITS-CLIP, AGO-CLEAR-CLIP (chimeric reads), HEAP (Halo-Ago2 mouse), chimeric eCLIP / miR-eCLIP (deep miRNA-target profiling), or CLASH using chimeric-read processing pipelines, seed-pairing analysis, and 3' auxiliary pairing rules. Use when distinguishing direct miRNA targets from indirect, integrating CLIP-derived target maps with TargetScan / miRDB / DIANA predictions, applying canonical 7mer-8mer seed matching with 3' UTR context, or recovering miRNA-mRNA chimeras at scale.
日本語の概要は準備中です。原文の説明を表示しています。
Structure retrieval, confidence-aware AlphaFold DB usage, coordinate download, PAE and pLDDT interpretation, and structure-guided biological annotation.
日本語の概要は準備中です。原文の説明を表示しています。
Query STRING for protein-protein interactions. Use when user asks about protein interactions, interaction networks, binding partners, or interactome. Triggers on "string", "protein interaction", "interaction network", "binding partners", "interactome", "PPI".
日本語の概要は準備中です。原文の説明を表示しています。
Reviewer role. Opens rendered HTML, inspects every slide visually, fixes problems in custom.css or slides.html and rebuilds through build-html.sh. Use whenever the user says "review", "QA", "check slides", "inspect", "audit", "proofread", or wants feedback on a rendered deck.
日本語の概要は準備中です。原文の説明を表示しています。
Internal — for Boundless team members only. Query Boundless broker telemetry tables on Redshift for prod/staging operational data. Use when the user asks about broker health, request evaluations, request completions, proving times, skip rates, telemetry data, or wants to run SQL against the telemetry database on live networks. Also covers historical telemetry through 2026-04-24 stored as Parquet archives in S3 (queried via DuckDB). Do NOT use for debugging local code changes, reviewing PRs, or investigating issues in the codebase itself.
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Use when a learner asks for help with MATLAB homework, labs, projects, graded assignments, take-home exams, quizzes, or any programming task where academic integrity, course policy, or instructor constraints may limit direct solutions. Use to provide policy-aware hints, conceptual coaching, partial feedback, and assignment-safe MATLAB tutoring.
日本語の概要は準備中です。原文の説明を表示しています。
Generate MATLAB Grader assessment items that are suitability-gated, profile-driven, feedback-aware, and validated through MATLAB MCP. Produces Script, Function, Class Definition, Class Inheritance, Object Usage, and Class Methods items with MATLAB Grader assessment setup instructions.
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Create and manage test data with factory patterns, fixture strategies, data anonymization, and synthetic data generation. Covers Fishery (TypeScript), FactoryBot (Ruby), Factory Boy (Python), database seeding, cleanup strategies, and GDPR-compliant data handling. Use when: "test data," "fixtures," "factories," "seed data," "synthetic data," "test database," "data anonymization." Not for: migration/integrity testing of the DB itself — use database-testing; environment provisioning and database branching strategy — use test-environments. Related: test-environments, database-testing, api-testing, unit-testing.
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Test payment and checkout flows end to end against PSP sandboxes — Stripe first, with the general pattern for Adyen/Braintree/PayPal. Covers Stripe test-mode card numbers and their decline codes, the 3DS/SCA challenge flow and its nested-iframe handling in Playwright, test clocks for subscription/billing-cycle simulation, webhook testing (stripe listen/trigger, signature verification, idempotency), failed/retried payments and refunds, and never using real cards. Use when: "test Stripe checkout," "payment test," "3DS test," "test webhook signature," "test subscription renewal," "test clock," "refund test," "decline card test," "checkout E2E." Not for: General API contract testing of non-payment endpoints — api-testing. PCI-DSS/regulatory compliance audit — compliance-testing. Related: api-testing, playwright-automation, compliance-testing, test-data-management, qa-project-context.
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Validate database integrity, test migrations forward and backward, verify schema constraints, manage seed data, detect migration drift, and identify query performance issues. Covers PostgreSQL, MySQL, MongoDB with Prisma, TypeORM, Drizzle, and SQLAlchemy, plus Testcontainers test databases. Use when: "database test," "migration test," "migration rollback," "rollback test," "data integrity," "SQL test," "schema validation," "seed data," "query performance," "Testcontainers." Not for: synthetic data generation/masking at scale — use test-data-management; Docker/IaC test-environment provisioning — use test-environments; SQL injection — use security-testing. Related: test-data-management, test-environments, security-testing, ci-cd-integration.
日本語の概要は準備中です。原文の説明を表示しています。
Define implementation contracts (APIs and data models) that developers will build against during PRD v0.6 Architecture. Triggers on requests to define APIs, design database schema, create data models, or when user asks "define APIs", "data model", "database schema", "API contracts", "technical spec", "endpoint design", "schema design". Consumes ARC- (architecture), TECH- (Build items), UJ- (flows), SCR- (screens). Outputs API- entries for endpoints and DBT- entries for data models. Feeds v0.7 Build Execution.
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Transform v0.6 specifications into context-window-sized work packages (EPICs) during PRD v0.7 Build Execution. Triggers on requests to create epics, scope work, break down implementation, or when user asks "create epics", "scope work", "break down work", "context window sizing", "what to build first?", "implementation planning", "epic breakdown". Consumes API-, DBT-, FEA-, ARC-. Outputs EPIC- entries with objectives, ID references, dependencies, and context windows. Feeds v0.7 Test Planning.
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Define test cases BEFORE implementation, ensuring every API, business rule, and user journey has verifiable acceptance criteria during PRD v0.7 Build Execution. Triggers on requests to define tests, plan test coverage, create test cases, or when user asks "define tests", "test planning", "what to test?", "test cases", "test coverage", "TEST-", "test-first". Consumes EPIC- (scope), API-, DBT-, BR-, UJ-. Outputs TEST- entries with Given-When-Then format. Feeds v0.7 Implementation Loop.
日本語の概要は準備中です。原文の説明を表示しています。
Format code with swiftlint and swiftformat
日本語の概要は準備中です。原文の説明を表示しています。
Lint code with swiftlint and swiftformat
日本語の概要は準備中です。原文の説明を表示しています。
Review the working-tree changes (vs main) for correctness, concurrency, architecture, testing, and API/doc issues — following .github/CODE_REVIEW.md — and return a severity-graded report. Scales the machinery to the diff size: a single code-reviewer agent for a small change, or a fan-out-and-verify Workflow for a large/multi-unit one. Produces findings; it does not apply fixes (the caller does).
日本語の概要は準備中です。原文の説明を表示しています。
Diagnose a failing CI workflow run (lint, markdown lint, build, or unit tests) — identify which job failed, the cause, and a concrete fix
日本語の概要は準備中です。原文の説明を表示しています。