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概要と使いどころ
Use when you have an existing component, flow, or interface and need an evidence-backed accessibility design review after basic checks pass. Best for WCAG 2.2 compliance, focus management, ARIA pattern quality, semantics, and state communication gaps automated tools miss.
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Use when you need to run real accessibility tests — Playwright keyboard interactions, axe-core scanning, visual regression, and WCAG 2.2 compliance checks. The measurement layer that feeds evidence into a11y-critic reviews.
日本語の概要は準備中です。原文の説明を表示しています。
Complete VPN server setup from scratch. Takes a fresh VPS (IP + root + password from hosting provider) through full server hardening and 3x-ui (Xray proxy panel) installation with VLESS Reality or VLESS TLS. Guides user through connecting via Hiddify client. Use when user mentions v2ray, xray, vless, 3x-ui, proxy server, vpn server, or wants to set up encrypted proxy access on a VPS. Designed for beginners — hand-holds through every step.
日本語の概要は準備中です。原文の説明を表示しています。
This skill should be used when agents need to log into websites, retrieve passwords, or access credentials. CRITICAL - always use find_credential with the website URL, never guess item names.
日本語の概要は準備中です。原文の説明を表示しています。
Implements permission-based authorization with custom attributes, policy providers, and authorization handlers. Provides granular access control beyond simple role-based authorization.
日本語の概要は準備中です。原文の説明を表示しています。
Review UI code for Web Interface Guidelines compliance. Use when asked to "review my UI", "check accessibility", "audit design", "review UX", or "check my site against best practices".
日本語の概要は準備中です。原文の説明を表示しています。
Technical SEO for AI search engines. Checks AI crawler accessibility, llms.txt compliance, robots.txt configuration, server-side rendering. Outputs problems + fixes (generates llms.txt, robots.txt modifications). Use when user says "AI crawlers", "llms.txt", "GPTBot", "GEO technical".
日本語の概要は準備中です。原文の説明を表示しています。
Research a specific company before applying or interviewing by gathering facts from primary and official sources, recording the source and date behind every claim, and keeping anonymous or unverifiable material clearly separated from confirmed fact. Use when a user asks what a company actually does, how it makes money, what its published conditions are, whether a posting matches the company's own disclosures, or what to verify before an interview; do not use to predict hiring outcomes, to repeat review-site content as fact, or to bulk-crawl sites that prohibit automated access.
日本語の概要は準備中です。原文の説明を表示しています。
Query UniProt's REST API (post-2022 endpoint at rest.uniprot.org) for protein sequences, annotations, GO terms, cross-references, ID mappings, and proteomes. Use when fetching UniProtKB entries, navigating the JSON schema, choosing between UniProtKB/UniRef/UniParc/Proteomes resources, deciding stream vs search endpoint for batch retrieval, running ID-mapping jobs with the async pattern, handling isoform suffixes, or filtering reviewed Swiss-Prot vs auto-annotated TrEMBL. Encodes the legacy URL migration (2022), the new JSON schema layout, and bulk-pull patterns.
日本語の概要は準備中です。原文の説明を表示しています。
Build enhancer-driven gene regulatory networks (eGRNs) by integrating single-cell RNA-seq and ATAC-seq using SCENIC+, CellOracle base GRNs, Pando, FigR, DIRECT-NET, TRIPOD, and scMEGA. Covers the accessibility-defines-enhancers principle, peak-to-gene linking and its cell-composition confound, the paired-vs-unpaired decision, and TF-region-gene eRegulon triplets. Use when analyzing 10x multiome or paired/unpaired scRNA+scATAC to infer cis-regulatory GRNs. For RNA-only regulons see scenic-regulons; for in silico TF perturbation see perturbation-simulation.
日本語の概要は準備中です。原文の説明を表示しています。
Download genome assemblies, gene records, and ortholog data from NCBI using the modern Datasets v2 CLI (replaces assembly_summary.txt scraping and many EFetch workflows). Use when bulk-pulling genome assemblies, gene metadata across species, ortholog sets, or BLAST databases; when E-utilities are too slow for genome-scale work; or when automatic checksum verification, parallel download, and clean accession-driven retrieval are required. Encodes the JSON-lines output format, dataformat conversion, --dehydrated for cloud workflows, and when Datasets is/isn't the right tool.
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Designs novel molecules using REINVENT 4 (de novo, scaffold decoration, linker design, R-group, molecular optimization), MolMIM, Diffusion-based generators (DiGress, DiffSMol), and JT-VAE with explicit handling of multi-parameter optimization (MPO), goal-directed scoring functions, transfer/reinforcement/curriculum learning, synthetic accessibility scoring, and chemical space exploration vs exploitation. Use when designing new chemical matter against a target, decorating a scaffold, linking fragments, or optimizing a hit for multiple ADMET / activity properties simultaneously.
日本語の概要は準備中です。原文の説明を表示しています。
Build a differential-ready consensus peakset from per-replicate ATAC-seq peaks using iterative overlap removal, fixed-width re-centering, and majority-rule overlap. Use when generating a stable peak coordinate system for downstream differential accessibility, ML feature engineering, cross-sample comparison, or fixed-width peak counts; covers Corces 2018 iterative overlap (501 bp), DiffBind summit re-centering, and ENCODE consistency rules.
日本語の概要は準備中です。原文の説明を表示しています。
Call accessible chromatin regions from ATAC-seq BAM files using MACS3, MACS2, Genrich, or HMMRATAC. Use when identifying open chromatin from aligned ATAC-seq, choosing between point-source vs HMM peak callers, applying ENCODE-style pseudoreplicate IDR, removing blacklist regions, or fixing 501bp consensus peaks for downstream differential analysis.
日本語の概要は準備中です。原文の説明を表示しています。
Create and use BAI/CSI indices for BAM/CRAM files using samtools and pysam. Use when enabling random access to alignment files or fetching specific genomic regions.
日本語の概要は準備中です。原文の説明を表示しています。
Process and analyze single-cell ATAC-seq data with Signac, ArchR, SnapATAC2, or Cell Ranger ATAC. Use when handling 10X scATAC or 10X Multiome (paired RNA+ATAC) data, performing per-cell QC, choosing between ArchR/Signac/SnapATAC2 ecosystems, building per-cluster consensus peaksets, integrating with paired scRNA-seq, doublet detection (AMULET vs ArchR vs scDblFinder), or running pseudobulk differential accessibility per cluster.
日本語の概要は準備中です。原文の説明を表示しています。
Detect transcription factor binding footprints in ATAC-seq using TOBIAS, HINT-ATAC, Wellington, or scprinter. Use when identifying bound TF sites within accessible regions, correcting Tn5 insertion bias before footprinting, choosing between cleavage-based and aggregate-based footprinters, or comparing differential TF activity between conditions.
日本語の概要は準備中です。原文の説明を表示しています。
Select, document, download, and checksum-verify the most appropriate NCBI reference genome on an HPC cluster. Use whenever an analysis needs a reference genome, genome FASTA, genome annotation, assembly accession, or genome index and no exact approved assembly is already available; when a user asks to fetch a species genome from NCBI; or when a pipeline must resolve and cache a reproducible reference assembly on a remote cluster.
日本語の概要は準備中です。原文の説明を表示しています。
Predict enhancer-gene regulatory connections from ATAC-seq using ABC, ENCODE-rE2G, HiChIP, or Cicero. Use when linking distal enhancers to target genes, choosing between contact-aware (ABC, ENCODE-rE2G), accessibility-only (Cicero), and orthogonal (HiChIP H3K27ac, EpiMap) approaches, validating predictions against CRISPRi-FlowFISH gold-standard, or building cell-type-specific regulatory maps for fine-mapping or therapeutic target discovery.
日本語の概要は準備中です。原文の説明を表示しています。
Spring Boot architecture patterns, REST API design, layered services, data access, caching, async processing, and logging. Use for Java Spring Boot backend work.
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Provides JWT authentication and authorization patterns for Spring Boot 3.5.x covering token generation with JJWT, Bearer/cookie authentication, database/OAuth2 integration, and RBAC/permission-based access control using Spring Security 6.x. Use when implementing authentication or authorization in Spring Boot applications.
日本語の概要は準備中です。原文の説明を表示しています。
Design, implement, review, and audit Android Jetpack Compose UI/UX for phone interfaces. Use when a request concerns concrete Compose layout, components, interaction, accessibility, or visual behavior. Do not activate for framework or dependency presence alone; non-UI Android work is excluded.
日本語の概要は準備中です。原文の説明を表示しています。
Security review checklist for Convex functions, auth logic, public queries, admin routes, webhooks, uploads, and AI-generated code. Use when reviewing code that touches user data, PII, or access control.
日本語の概要は準備中です。原文の説明を表示しています。
Sets up Convex auth, identity mapping, and access control. Use for login, auth providers, users tables, protected functions, or roles in a Convex app.
日本語の概要は準備中です。原文の説明を表示しています。