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cccskills

「research」の検索結果

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概要と使いどころ

Use when building a weighted gene co-expression network from a bulk expression matrix and a sample group file, filtering variable genes by MAD, identifying co-expression modules with WGCNA, correlating modules with traits, and exporting module-level plots and gene tables. NOT for single-cell RNA-seq, differential expression testing, methylation analysis, or datasets that are too small for WGCNA after quality control.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Use when constructing a prognosis nomogram from survival-related clinical predictors, exporting the nomogram bundle and C-index table, and optionally rendering the final nomogram PDF. NOT for: univariate/multivariable Cox feature screening, calibration curves, ROC analysis, decision-curve analysis, or non-survival outcomes.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Explains why studies on the same biomedical topic reach different or opposing conclusions by auditing differences in population, endpoint definition, sample source, assay or platform, study design, statistical model, adjustment strategy, validation chain, and bias control. It separates true contradiction from apparent contradiction caused by framing or methods. Never fabricate references, PMIDs, DOIs, trial identifiers, dataset details, platform details, study features, or conflict explanations that are not supported by the input.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Systematically maps mechanism evidence for a disease from molecules to pathways, cell types, tissues, biological consequences, and clinical phenotypes. Always use this skill when a user needs a layered mechanism evidence chain rather than a flat summary or immediate gap analysis. Formal literature citations must be real and verifiable.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Use when you need a standardized R CLI workflow to build a protein-protein interaction network from a local gene list and an offline STRING cache, export node and edge tables, and render a reproducible PDF network plot. NOT for online API fetching, arbitrary graph databases, multi-omics integration, or non-STRING interaction sources.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Use when building XGBoost models on tabular data and returning feature importance ranking outputs. Supports binary classification and regression with automatic task detection, train-test split, performance tables, feature importance ranking tables, and PNG importance plots.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Use when generating Sankey or alluvial plots from sample annotation tables where rows are samples and selected columns are categorical stages such as risk group, response status, subtype, or cohort labels. NOT for: gene network flow analysis, continuous-value trajectories, or graph-structured pathway visualization.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Scrum-inspired paper review, revision, and R&R workflow. Handles docx/tex/md/PDF in English or Chinese. Auto-detects manuscript stage, estimates sprint count, runs multi-lens review (Contribution/Rigor/Writing/Editor), generates prioritized revision backlog, exports MD/DOCX/PDF/HTML reports. Use when asked to review a paper, revise based on reviewer comments, handle R&R, respond to peer review, plan paper revision sprints, or when user types /ps or /papersprint.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Use when building a sample-level hierarchical clustering dendrogram from a bulk expression matrix and sample annotation table, especially for QC, batch inspection, or sample similarity assessment. Trigger keywords: hierarchical clustering, dendrogram, sample QC, batch inspection, sample similarity. NOT for: differential expression testing, gene clustering heatmaps, single-cell clustering workflows.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Run immune pathway GSVA or ssGSEA analysis from a bulk expression matrix, a sample group file, and a local immune Reactome gene-set table, then export differential pathway results and a heatmap for two-group comparison.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Writes Specific Aims pages for grant applications. Use when drafting or revising the Specific Aims page (NIH R01/R21/R03), NSF Project Summary, or equivalent for any major funding agency. Also triggers on "write my specific aims", "help me draft specific aims for NIH", "what should a specific aims page include", "NSF project summary", "write my grant aims", or "how do I structure an R01".

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Improves medical English precision without changing the underlying facts, evidence boundaries, or intended scientific meaning.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Checks biomedical manuscripts against reporting guidelines such as CONSORT, STROBE, PRISMA, and TRIPOD to identify missing or weak reporting elements before submission or revision.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Checks consistency across title, abstract, methods, results, figures, tables, and supplements to identify internal contradictions and version drift in biomedical manuscripts.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Converts a biomedical study storyline into a graphical abstract and, when direct image capability is available, generates the graphical abstract directly; otherwise it falls back to prompts, Mermaid flowcharts, or designer-facing briefs.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Converts biomedical table content into clear manuscript or presentation narrative by prioritizing meaningful patterns, contrasts, and interpretation boundaries rather than restating every number.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Use when performing GO and KEGG enrichment on a gene list from bulk RNA-seq or microarray studies, then generating a combined GO/KEGG dot chart. NOT for single-cell RNA-seq, methylation data, or non-expression data.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Use when normalizing bulk gene or protein expression matrices with log2 transform, z-score standardization, or min-max scaling before downstream visualization or exploratory analysis. NOT for count-model normalization such as TPM/DESeq2 size factors, batch correction, or single-cell preprocessing.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Acknowledges limitations in sample, design, measurement, and validation in a professional way that improves credibility without undermining the whole paper. Use when writing the limitations paragraph of a Discussion section, preparing a grant risk assessment, responding to reviewers about study weaknesses, or framing scope boundaries for a paper. Also triggers on "write my limitations", "how should I address the limitation of", "reviewer said my sample is too small", or "help me word this limitation".

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Matches your study to appropriate journals based on topic, design, and evidence strength. Use when deciding where to submit a manuscript, comparing journal options by impact factor vs scope fit vs method tolerance, or finding a realistic submission target after a rejection. Also triggers on "where should I submit this paper", "which journal is best for my study", "find journals for my manuscript", "is this a good fit for [journal]", or "I need a journal with IF around X".

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Writes the full Results section of a biomedical manuscript from a sufficiently clear result structure, figure inventory, or analysis summary while preserving evidence boundaries and result hierarchy.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Drafts journal-ready cover letters for manuscript submission. Use when preparing a submission package, communicating the manuscript's contributions and journal fit to editors, or tailoring the novelty framing for a specific journal's scope. Also triggers on "write a cover letter for my paper", "draft a submission cover letter", "help me write to the editor", or "cover letter for [journal name]".

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Use when validating an existing prognostic risk signature on an external bulk expression cohort with survival outcomes, producing risk scores, Kaplan-Meier curves, risk distribution plots, heatmap, and time-dependent ROC curves. NOT for: model training, feature selection, nomogram construction, calibration analysis, or single-cell data.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新

Builds background-gap-objective logic for biomedical manuscript introductions with clear study positioning and disciplined narrative structure.

日本語の概要は準備中です。原文の説明を表示しています。

aipoch/medical-research-skills1,9672026年9月17日 更新