342 件 ・ 関連度順
概要と使いどころ
Search NCBI databases using Biopython Bio.Entrez (ESearch, EInfo, EGQuery, ESpell). Use when finding records by keyword, building reproducible field-qualified queries, navigating the Entrez Query Translator, exploiting the history server for large result sets, handling retmax caps, or interpreting weekly index lag. Covers PubMed, Nucleotide, Protein, Gene, SRA, GEO, Assembly, Taxonomy, ClinVar, dbSNP.
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Model gene-family birth-death dynamics across a species tree using CAFE5 (Mendes et al 2020 Bioinformatics 36:5516 gamma-distributed rate categories), CAFE5-error (annotation-error-aware), Count (Csurös 2010 ancestral state reconstruction), BadiRate (Librado 2012 likelihood + parsimony), DupliPHY-Family, and ALE/AleRax (for per-family DTL; see [[gene-tree-species-tree-reconciliation]]). Test lineage-specific gene-family expansions and contractions, distinguish biological dynamics from annotation artifacts, account for assembly fragmentation, identify functional enrichment in expanded / contracted families. Use when correlating gene-family changes with phenotype evolution, ranking lineages by adaptive gene-family-rate shifts, post-WGD dosage-balance analysis, or building Birth-death models from OrthoFinder presence/absence matrices.
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Generate, fill, and assemble PDF documents at scale. Handles legal forms, contracts, invoices, certificates. Supports form filling (pdf-lib), template rendering (Puppeteer, LaTeX), digital signatures (DocuSign), and document assembly. Use for legal tech, HR automation, invoice generation. Activate on "PDF generation", "form filling", "document automation", "digital signatures". NOT for simple PDF viewing, basic file conversion, or OCR text extraction.
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Expert in ALL computational collage composition: photo mosaics, grid layouts, scrapbook/journal styles, magazine editorial, vision boards, mood boards, social media collages, memory walls, abstract/generative arrangements, and art-historical techniques (Hockney joiners, Dadaist photomontage, Surrealist assemblage, Rauschenberg combines). Masters edge-based assembly, Poisson blending, optimal transport color harmonization, and aesthetic optimization. Activate on 'collage', 'photo mosaic', 'grid layout', 'scrapbook', 'vision board', 'mood board', 'photo wall', 'magazine layout', 'Hockney', 'joiner', 'photomontage'. NOT for simple image editing (use native-app-designer), generating new images (use Stability AI), single photo enhancement (use photo-composition-critic), or basic image similarity search (use clip-aware-embeddings).
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Build audio transcription pipelines with Whisper, Deepgram, and AssemblyAI including speaker diarization and real-time streaming. Activate on: transcription, speech-to-text, diarization, audio processing, meeting transcripts. NOT for: text-to-speech synthesis (voice-audio-engineer), music generation (ai-engineer).
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Expert-level nanotechnology covering nanomaterials, nanofabrication, characterization methods, nanoelectronics, nanomedicine, and self-assembly.
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Build repeatable data-to-Docs pipelines from Sheets and Drive sources. Use for automated status reports, template-based document assembly, and scheduled publishing workflows.
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Builds and improves task-specific decision artifacts from application requirements and labeled records. Use for data assembly, primitive and base-model selection, fitting, export/reload, inference policy, or bounded data/model/program improvement. Includes rules and no-training outcomes; does not require a rung ladder or training a general Jev.
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Implement or extend a CPU architecture, processor variant, instruction set, addressing modes, registers, interrupts, bus transactions, disassembly, timing, and processor tests in EMULATORS. Use when adding a processor not yet emulated, deriving a CPU from F6500, FZ80, or another family, filling missing opcodes, correcting instruction semantics or cycles, or creating exhaustive instruction and interrupt tests.
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Use when planning the migration of a legacy system or monolith — analyzes the source codebase (current repo, or a repo URL cloned to a temp dir) and produces an evidence-based Strangler Fig migration plan with per-domain SPECs. Default target is .NET (Blazor WebAssembly, .NET MAUI, ASP.NET Core); other stacks allowed by user decision. Do NOT use to implement code or when approved SPECs already cover the migration.
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Reverse engineer Go-compiled malware using Ghidra with specialized scripts for function recovery, string extraction, and type reconstruction in stripped Go binaries.
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Use when designing, evaluating, documenting, modernizing, reviewing, refactoring, or implementing software architecture and code-level structure, including requirements, context, architecture style selection, microservices patterns, WebAssembly/WASI/Component Model, UMA portable capabilities, runtime contracts, capability graphs, governed MCP/agent orchestration, clean code, code smells, Rust crate/library API architecture, Cargo feature/MSRV/SemVer policy, unsafe/FFI/no_std/library testing, modularity, views, NFR tactics, IAM/auth, security patterns, cost estimation, architecture-as-code fitness functions, ADR/RFC work, and engineering execution plans.
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Turn an approved topic into a narrated, non-presenter video using a script, voice asset, visual coverage, assembly, and captions.
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Develop a short scripted micro-drama from an idea or approved script through character sheets, storyboard frames, animated shots, and a reviewable assembly.
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Turn approved video clips, audio, captions, and timing decisions into an ordered, reviewable draft while preserving a reproducible timeline.
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Turn one approved topic into a curiosity-led 3D educational short with character sheets, ordered keyframes, motion clips, narration, captions, and an auditable assembly plan.
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Master binary analysis patterns including disassembly, decompilation, control flow analysis, and code pattern recognition. Use when analyzing executables, understanding compiled code, or performing...
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Diagnose MSBuild build performance bottlenecks using binary log analysis. Only activate in MSBuild/.NET build context. USE FOR: identifying why builds are slow by analyzing binlog performance summaries, detecting ResolveAssemblyReference (RAR) taking >5s, Roslyn analyzers consuming >30% of Csc time, single targets dominating >50% of build time, node utilization below 80%, excessive Copy tasks, NuGet restore running every build. Covers timeline analysis, Target/Task Performance Summary interpretation, and 7 common bottleneck categories. Use after build-perf-baseline has established measurements. DO NOT USE FOR: establishing initial baselines (use build-perf-baseline first), fixing incremental build issues (use incremental-build), parallelism tuning (use build-parallelism), non-MSBuild build systems. INVOKES: binlog MCP server tools (overview, errors, search, items, properties); falls back to dotnet msbuild binlog replay + grep/cat when the MCP is unavailable.
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Guide for modernizing and migrating MSBuild project files to SDK-style format. Only activate in MSBuild/.NET build context. USE FOR: converting legacy .csproj/.vbproj with verbose XML to SDK-style, migrating packages.config to PackageReference, removing Properties/AssemblyInfo.cs in favor of auto-generation, eliminating explicit <Compile Include> lists via implicit globbing, consolidating shared settings into Directory.Build.props. Indicators of legacy projects: ToolsVersion attribute, <Import Project="$(MSBuildToolsPath)">, .csproj files > 50 lines for simple projects. DO NOT USE FOR: projects already in SDK-style format, non-.NET build systems (npm, Maven, CMake), .NET Framework projects that cannot move to SDK-style. INVOKES: dotnet try-convert, upgrade-assistant tools.
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Scaffold, build, and package SwiftPM-based macOS apps without an Xcode project. Use when you need a from-scratch macOS app layout, SwiftPM targets/resources, a custom .app bundle assembly script, or signing/notarization/appcast steps outside Xcode.
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Comprehensive patterns and techniques for analyzing compiled binaries, understanding assembly code, and reconstructing program logic.
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Rev kategorisi SKILL.md — Binary analysis, disassembly, symbolic execution araçları kurma rehberi
日本語の概要は準備中です。原文の説明を表示しています。
Reverse engineer Go-compiled malware using Ghidra with specialized scripts for function recovery, string extraction, and type reconstruction in stripped Go binaries.
日本語の概要は準備中です。原文の説明を表示しています。
Orchestrates an end-to-end long-read structural-variant pipeline - basecalling to minimap2 alignment (platform-matched preset) to Sniffles2/cuteSV/pbsv calling to optional assembly-based calling (dipcall/PAV) to two-step .snf cohort merging to Truvari benchmarking - chaining ONT and PacBio HiFi runs while handing the SV signal mechanism off to the component skills. Use when running a long-read SV workflow from reads to a benchmarked callset, choosing the minimap2 preset and SV caller by platform and goal, deciding when long reads are worth it for the insertions and repeat-mediated SVs short reads physically miss, building a joint-genotyped cohort with the two-step .snf design, or parameterizing a Truvari benchmark against GIAB HG002 Tier 1 plus CMRG. Not for the SV signal mechanism itself (see variant-calling/structural-variant-calling) or short-read SV.
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