491 件 ・ 関連度順
概要と使いどころ
Operate the Deep Researcher Agent repository for autonomous deep-learning experiments, execution backends, provider/tool dispatch, GPU resources, durable progress, and research-support integrations.
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Research why neural architectures and training methods work through forward computation, geometry, gradients, optimization dynamics, historical experiments, and competing explanations. Use for deep mechanism questions about neural networks, AI models, layers, representations, or training; explain the meaning in plain language with evidence and explicit limits.
日本語の概要は準備中です。原文の説明を表示しています。
Throwaway experiments to validate an idea before build.
日本語の概要は準備中です。原文の説明を表示しています。
Turn vague or partially formed AI, computer-science, data-driven, and engineering-method research directions into evidence-grounded, falsifiable, paper-ready Research Idea Briefs through heuristic questioning, staged confirmation, literature positioning, novelty attack, and method-figure planning. Use when the user needs to clarify a research idea, formalize inputs/outputs/objectives/constraints, frame background and motivation, select 3-5 anchor papers, identify a defensible gap, derive 2-3 contributions, stress-test novelty, or design an input-to-output method framework and core-paper figure. Also trigger on requests such as 明确科研 idea、启发式梳理 idea、互动追问科研问题、梳理论文创新点、定义研究任务、找对标论文、把研究方向变成论文方案、画方法框架图. Do not use as the primary workflow for running experiments, exhaustive systematic reviews, drafting full manuscript sections, or polishing finished prose.
日本語の概要は準備中です。原文の説明を表示しています。
Best practices for designing reproducible experiments
日本語の概要は準備中です。原文の説明を表示しています。
Experiment executor and monitor for academic research. 2-agent system covering code experiments (ML training, statistical analysis, ETL, simulation) and human studies (surveys, field studies, interviews). 4 modes: run (execute + monitor code), manage (track human studies), validate (statistical interpretation + reproducibility verification), plan (Socratic experiment design). Use when a researcher wants to run or monitor a research experiment, manage or resume a human-subject study, check the statistics or reproducibility of research results, or design an experiment or study, in English or Chinese (e.g., 跑實驗、管理研究、驗證結果、規劃實驗).
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end CRISPR experiment design from target selection to delivery-ready constructs. Covers guide RNA design, off-target assessment, and specialized editing strategies including knockouts, base editing, and HDR knockins. Use when designing complete CRISPR editing experiments for gene knockout, correction, or tagging.
日本語の概要は準備中です。原文の説明を表示しています。
Identify differentially bound regions across CLIP-seq conditions (knockdown vs control, treatment vs vehicle, disease vs healthy) using DEWSeq (sliding-window DESeq2), Flipper (Skipper-downstream), ASpeak, edgeR, or limma-voom. Use when computing condition-level changes in RBP binding intensity, choosing peak-level vs window-level vs crosslink-level testing, designing replicate experiments, or distinguishing biological binding shifts from technical confounders.
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Detects circadian and ultradian rhythms in time-series omics data using CosinorPy cosinor models, MetaCycle (JTK_CYCLE, ARSER), and RAIN non-parametric tests. Fits cosine models to estimate phase and amplitude, tests rhythmicity significance at pre-specified periods. Use when testing for 24-hour or other known-period oscillations in circadian, feeding-fasting, or light-dark cycle experiments. Not for unknown-period discovery (see temporal-genomics/periodicity-detection).
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Visualizes ChIP-seq data using deepTools (computeMatrix, plotHeatmap, plotProfile, bamCoverage, bamCompare), pyGenomeTracks (modern INI-driven track plots), Gviz (R browser-style), EnrichedHeatmap (ComplexHeatmap-based), ChIPseeker tag heatmaps, and IGV batch screenshots. Handles bigWig normalization choices (CPM, BPM, RPGC, spike-in scaled), bamCompare operations (log2 ratio, subtract, SES), k-means clustering of heatmaps for biological subgrouping, and spike-in-scaled tracks for global-shift experiments. Use when generating publication-quality ChIP-seq signal heatmaps, profile plots, genome-browser tracks, or comparing samples visually.
日本語の概要は準備中です。原文の説明を表示しています。
Predict RBP binding from RNA sequence using deep learning models (RBPNet sequence-to-signal, RNAProt RNN, GraphProt2 GCN with structure, DeepCLIP, DeepRiPe multi-modal CNN) for variant-effect prediction, in silico binding-site discovery, model interpretation, and transfer learning from CLIP and RBNS datasets. Use when computational prediction of RBP binding from sequence is needed, evaluating variant effects on binding without further wet-lab experiments, comparing model performance, or training a custom model on ENCODE eCLIP data.
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Design guides for cytosine and adenine base editing using editing window optimization and BE-Hive outcome prediction. Select optimal positions for C-to-T or A-to-G conversions without double-strand breaks. Use when designing base editor experiments for precise nucleotide changes.
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SPR and BLI assay planning, kinetic interpretation, and troubleshooting guidance. Use when: (1) Planning binding kinetics experiments, (2) Troubleshooting poor/no binding signal, (3) Interpreting kinetic data artifacts, (4) Choosing between SPR vs BLI platforms.
日本語の概要は準備中です。原文の説明を表示しています。
Cell-free protein synthesis (CFPS) planning and optimization guidance. Use when: (1) Planning CFPS experiments, (2) Troubleshooting low yield or aggregation, (3) Optimizing DNA template design for CFPS, (4) Expressing difficult proteins (disulfide-rich, toxic, membrane).
日本語の概要は準備中です。原文の説明を表示しています。
Guidance for cell-free protein synthesis (CFPS) optimization. Use when: (1) Planning CFPS experiments, (2) Troubleshooting low yield or aggregation, (3) Optimizing DNA template design for CFPS, (4) Expressing difficult proteins (disulfide-rich, toxic, membrane).
日本語の概要は準備中です。原文の説明を表示しています。
Call the free Agnes text model API for chat completions, streaming answers, coding help, tool-calling experiments, and OpenAI-compatible text generation. Use when the user asks for 免费文本, 免费的文本模型, free text API, Agnes text, Agnes-2.0-Flash, free LLM calls, or wants to use a free chat/completion model through an Agent skill.
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Operate professional paid advertising across Google, Meta, YouTube, LinkedIn, TikTok, Microsoft, Apple, Amazon, Reddit, Pinterest, Snapchat, and X. Use for account intake, source-grounded audits, strategy, budget and measurement planning, creative production, experiments, reporting, monitoring, and explicitly approved campaign changes. Also trigger on PPC, paid social, retail media, attribution, tracking, landing pages, cross-platform conversion totals, negative keywords or search terms, beta-feature scoring, stale platform claims, API-token or credential setup, campaign deletion, and safe Claude Ads installation or uninstall.
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Validate system resilience through controlled fault injection. Covers hypothesis-driven chaos experiments, failure injection types (network, service, infrastructure, dependency), LitmusChaos/Chaos Mesh/AWS FIS/Gremlin/toxiproxy tooling, automated abort gating, game day planning, and progressive chaos adoption. Use when: "chaos engineering," "fault injection," "resilience test," "game day," "failure recovery," "system reliability," "blast radius." Not for: safe rollout flags/canary/dark launch during a release — use testing-in-production; designing new tests from production telemetry — use observability-driven-testing. Related: testing-in-production, observability-driven-testing, performance-testing, release-readiness, test-environments.
日本語の概要は準備中です。原文の説明を表示しています。
Data Version Control for ML projects. Track large datasets and models alongside Git, build reproducible ML pipelines, and run experiments with metric comparison. Works with any storage backend including S3, GCS, Azure, and local filesystems.
日本語の概要は準備中です。原文の説明を表示しています。
DevOps 与站点可靠性工程 (SRE) — 平台 / 基础设施 / 可靠性工程师的认知操作系统, 覆盖软件交付 + 运维全生命周期 (CI/CD 与发布工程 trunk-based + 渐进式发布 canary/blue-green/feature flag + GitOps Argo CD/Flux / 基础设施即代码 Terraform/OpenTofu/Pulumi/Ansible + policy-as-code OPA / 容器与编排 Docker/Kubernetes + Helm/Kustomize + service mesh Istio/Linkerd / 可观测性 Prometheus + Loki + OpenTelemetry + Honeycomb + eBPF + RED/USE / SLO-SLI-error budget 与可靠性工程 Google SRE 学科 + 容量规划 + 优雅降级 / 事件管理与 on-call 事件指挥 + PagerDuty + runbook + 无指责复盘 + MTTR / 云平台与 FinOps AWS/GCP/Azure + 成本优化 + 弹性伸缩 / 平台工程与开发者体验 IDP + Backstage + golden path + Team Topologies / DevSecOps 与供应链安全 shift-left + SBOM + SLSA + sigstore + Vault / 韧性与混沌工程 fault injection + game day + 安全科学 / DORA 指标与工程效能 部署频率 + 变更前置时间 + 变更失败率 + Accelerate 研究 / 数据库与有状态运维 schema 迁移 + 备份容灾) — 不含 通用应用开发 / 纯云销售认证速成 / 'DevOps = 跑 Jenkins 的岗位' 窄化误解 / ITIL 工单文化传统运维 (旧范式仅做边界) / 把手工运维 ClickOps 当稳态 (是 toil, 本 skill 核心反模式) (DevOps & Site Reliability Engineering — the cognitive operating system of platform / infrastructure / reliability practitioners who own the full software delivery + operational lifecycle, covering (a) CI/CD & release engineering (build pipelines, trunk-based development, progressive delivery — canary / blue-green / feature flags, GitOps with Argo CD / Flux), (b) Infrastructure as Code (Terraform / OpenTofu, Pulumi, CloudFormation, Ansible, Crossplane — module design, state management, drift, policy-as-code OPA / Sentinel / Checkov), (c) containers & orchestration (Docker / OCI, Kubernetes — scheduling, networking CNI, storage CSI, operators / CRDs, Helm / Kustomize, service mesh Istio / Linkerd), (d) observability (the three pillars + beyond — metrics Prometheus / VictoriaMetrics, logs Loki / ELK, traces OpenTelemetry / Jaeger / Tempo, high-cardinality observability Honeycomb, eBPF, RED / USE methods, SLO-based alerting), (e) SLO / SLI / error budgets & reliability engineering (Google SRE discipline — service level objectives, error budget policy, toil budgets, capacity planning, load shedding, graceful degradation), (f) incident management & on-call (incident command, PagerDuty / Opsgenie, runbooks, blameless postmortems, MTTR / MTTD, error budget burn), (g) cloud platforms & FinOps (AWS / GCP / Azure well-architected, multi-region, cost optimization, autoscaling), (h) platform engineering & developer experience (internal developer platforms, Backstage, golden paths, self-service, Team Topologies), (i) DevSecOps & supply-chain security (shift-left, SAST / DAST, SBOM, SLSA, sigstore / cosign, secrets management Vault), (j) resilience & chaos engineering (chaos experiments, fault injection, game days, resilience engineering / safety science), (k) DORA metrics & engineering effectiveness (deployment frequency, lead time, change failure rate, MTTR, the Accelerate research), (l) databases & stateful operations (schema migrations, backups / DR, replication); NOT generic software development / app feature coding (是 平行学科, DevOps/SRE 关注 delivery + operability 不是 product feature), NOT pure cloud sales / certification cram without operational depth, NOT 'DevOps = a job title that runs Jenkins' 的窄化误解 (DevOps 是 文化 + 实践, SRE 是 Google 对 reliability 的工程化具体实现), NOT ITIL-heavy 传统运维 工单文化 (是 被 DevOps 取代的旧范式, 仅做边界标注), NOT manual ops / ClickOps as a steady state (是 toil, 本 skill 的核心反模式).) Master OS — automated mastery of DevOps & Site Reliability Engineering — the cognitive operating system of platform / infrastructure / reliability practitioners who own the full software delivery + operational lifecycle, covering (a) CI/CD & release engineering (build pipelines, trunk-based development, progressive delivery — canary / blue-green / feature flags, GitOps with Argo CD / Flux), (b) Infrastructure as Code (Terraform / OpenTofu, Pulumi, CloudFormation, Ansible, Crossplane — module design, state management, drift, policy-as-code OPA / Sentinel / Checkov), (c) containers & orchestration (Docker / OCI, Kubernetes — scheduling, networking CNI, storage CSI, operators / CRDs, He
日本語の概要は準備中です。原文の説明を表示しています。
When the user wants to plan, design, or implement an A/B test or experiment, or build a growth experimentation program. Also use when the user mentions "A/B test," "split test," "experiment," "test this change," "variant copy," "multivariate test," "hypothesis," "should I test this," "which version is better," "test two versions," "statistical significance," "how long should I run this test," "growth experiments," "experiment velocity," "experiment backlog," "ICE score," "experimentation program," or "experiment playbook." Use this whenever someone is comparing two approaches and wants to measure which performs better, or when they want to build a systematic experimentation practice. For tracking implementation, see analytics. For page-level conversion optimization, see cro.
日本語の概要は準備中です。原文の説明を表示しています。
Use when 王建硕 wants to systematically grow his X (Twitter) followers by running numbered, A/B-testable growth experiments and tracking which ones actually work. Every action gets a number, a hypothesis, a target metric, a before-state (for rollback), and a verdict. The North-Star metric is the new-follower ÷ profile-visit ratio (conversion) — every profile change is judged against it. Daily it ingests the X Analytics CSV export, scores each running experiment, and recommends keep / rollback. Triggers — "涨粉", "增加 X 粉丝", "X 涨粉实验", "follower growth", "A/B test my profile", "今天的涨粉检查", "/wjs-x-increasing-follower".
日本語の概要は準備中です。原文の説明を表示しています。
Applies the operational and scientific frameworks of Stacey Gabriel (genomicist and sequencing platform leader at the Broad Institute). Use this skill whenever the user is designing large-scale biomedical research, operationalizing lab workflows, standardizing data governance, or transitioning from bespoke academic experiments to industrial-scale science. It is highly relevant for queries involving genomics, precision medicine, multiomics, cellular perturbation pipelines, or building massive datasets to fuel AI. Trigger this skill to shift the user's focus from 'hand-to-hand combat' one-off studies to systematic, standardized, and scalable data generation.
日本語の概要は準備中です。原文の説明を表示しています。
Transform research into Opportunity Solution Tree (Teresa Torres method). Map outcomes, opportunities, solutions, and experiments.
日本語の概要は準備中です。原文の説明を表示しています。