「threshold」の検索結果

ESM2 protein language model for embeddings and sequence scoring. Use this skill when: (1) Computing pseudo-log-likelihood (PLL) scores, (2) Getting protein embeddings for clustering, (3) Filtering designs by sequence plausibility, (4) Zero-shot variant effect prediction, (5) Analyzing sequence-function relationships. For structure prediction, use chai or boltz. For QC thresholds, use protein-qc.

日本語の概要は準備中です。原文の説明を表示しています。

AlphaFold2 / AlphaFold-Multimer structure prediction for validation and confidence scoring. Use this skill when: (1) Validating designed sequences fold correctly, (2) Predicting binder-target complex structures, (3) Calculating confidence metrics (pLDDT, pTM, ipTM), (4) Self-consistency validation of designs, (5) Multi-chain complex prediction with AlphaFold-Multimer. For faster single-chain prediction, use esm2-sequence-scoring. For QC thresholds, use protein-design-qc.

日本語の概要は準備中です。原文の説明を表示しています。

End-to-end guidance for protein design pipelines. Use this skill when: (1) Starting a new protein design project, (2) Need step-by-step workflow guidance, (3) Understanding the full design pipeline, (4) Planning compute resources and timelines, (5) Integrating multiple design tools. For tool selection, use binder-design. For QC thresholds, use protein-qc.

日本語の概要は準備中です。原文の説明を表示しています。

Validate protein designs using AlphaFold2 structure prediction. Use this skill when: (1) Validating designed sequences fold correctly, (2) Predicting binder-target complex structures, (3) Calculating confidence metrics (pLDDT, pTM, ipTM), (4) Self-consistency validation of designs, (5) Multi-chain complex prediction with AlphaFold-Multimer. For faster single-chain prediction, use esm. For QC thresholds, use protein-qc.

日本語の概要は準備中です。原文の説明を表示しています。

Chai-1 structure prediction for protein complexes and design validation. Use this skill when: (1) Predicting protein-protein complex structures, (2) Validating designed binders, (3) Predicting protein-ligand complexes, (4) Using the Chai API for high-throughput prediction, (5) Need an alternative to AlphaFold2. For QC thresholds, use protein-design-qc. For AlphaFold2 prediction, use alphafold2-multimer. For ESM-based analysis, use esm2-sequence-scoring.

日本語の概要は準備中です。原文の説明を表示しています。

End-to-end binder design using BindCraft hallucination. Use this skill when: (1) Designing protein binders with built-in AF2 validation, (2) Running production-quality binder campaigns, (3) Using different design protocols (fast, default, slow), (4) Need joint backbone and sequence optimization, (5) Want high experimental success rate. For backbone-only generation, use rfdiffusion. For QC thresholds, use protein-qc. For tool selection guidance, use binder-design.

日本語の概要は準備中です。原文の説明を表示しています。

Binder design ranking using ipSAE (interprotein Score from Aligned Errors). Use this skill when: (1) Ranking binder designs for experimental testing, (2) Filtering BindCraft or RFdiffusion outputs, (3) Comparing AF2/AF3/Boltz predictions, (4) Predicting binding success rates, (5) Need better ranking than ipTM or iPAE. For structure prediction, use chai or alphafold. For QC thresholds, use protein-qc.

日本語の概要は準備中です。原文の説明を表示しています。

Boltz-1 / Boltz-2 structure prediction for proteins, complexes, and ligand-aware validation. Use this skill when: (1) Predicting protein complex structures, (2) Validating designed binders, (3) Need open-source alternative to AF2, (4) Predicting protein-ligand complexes, (5) Using local GPU resources. For QC thresholds, use protein-design-qc. For AlphaFold2 prediction, use alphafold2-multimer. For Chai prediction, use chai1-structure-prediction.

日本語の概要は準備中です。原文の説明を表示しています。

ESM2 protein language model for sequence scoring, embeddings, and plausibility checks. Use this skill when: (1) Computing pseudo-log-likelihood (PLL) scores, (2) Getting protein embeddings for clustering, (3) Filtering designs by sequence plausibility, (4) Zero-shot variant effect prediction, (5) Analyzing sequence-function relationships. For structure prediction, use chai1-structure-prediction or boltz-structure-prediction. For QC thresholds, use protein-design-qc.

日本語の概要は準備中です。原文の説明を表示しています。

Generate protein backbones using RFdiffusion, a diffusion-based generative model for de novo protein structure generation. Use this skill when: (1) Designing binder scaffolds for a target protein, (2) Generating novel protein backbones from scratch, (3) Scaffolding functional motifs into new proteins, (4) Specifying hotspot residues for interface design, (5) Creating symmetric oligomers. For sequence design after backbone generation, use proteinmpnn. For structure validation, use alphafold or chai. For QC thresholds, use protein-qc.

日本語の概要は準備中です。原文の説明を表示しています。

End-to-end protein design pipeline guide across preparation, generation, validation, and filtering. Use this skill when: (1) Starting a new protein design project, (2) Need step-by-step workflow guidance, (3) Understanding the full design pipeline, (4) Planning compute resources and timelines, (5) Integrating multiple design tools. For tool selection, use binder-design-tool-selection. For QC thresholds, use protein-design-qc.

日本語の概要は準備中です。原文の説明を表示しています。

Structure prediction using Chai-1, a foundation model for molecular structure. Use this skill when: (1) Predicting protein-protein complex structures, (2) Validating designed binders, (3) Predicting protein-ligand complexes, (4) Using the Chai API for high-throughput prediction, (5) Need an alternative to AlphaFold2. For QC thresholds, use protein-qc. For AlphaFold2 prediction, use alphafold. For ESM-based analysis, use esm.

日本語の概要は準備中です。原文の説明を表示しています。

Define monitoring strategy, metrics collection, and alerting thresholds during PRD v0.8 Deployment & Ops. Triggers on requests to set up monitoring, define alerts, or when user asks "what should we monitor?", "alerting strategy", "observability", "metrics", "SLOs", "dashboards", "monitoring setup". Outputs MON- entries with monitoring rules and alert configurations.

日本語の概要は準備中です。原文の説明を表示しています。

Design analytics-driven browser test matrices and execute cross-browser tests. Covers BrowserStack/Sauce Labs configuration, Playwright browser channels, common cross-browser CSS/JS divergences, a known-issues documentation log, and progressive enhancement validation. Use when: "cross-browser," "browser matrix," "BrowserStack," "Safari issues," "browser compatibility," "Edge," "works in Chrome but not Safari." Not for: pixel-level baseline strategy and threshold tuning — use visual-testing; device-farm testing of native/hybrid apps — use mobile-testing. Related: visual-testing, playwright-automation, ci-cd-integration, mobile-testing.

日本語の概要は準備中です。原文の説明を表示しています。

Implement visual regression testing with Playwright screenshots, Chromatic, Percy, and Argos CI. Covers baseline management, diff threshold tuning, dynamic content masking, responsive viewport testing, and review/approval workflows. Use when: "visual test," "screenshot," "visual regression," "pixel diff," "snapshot diff," "update baselines," "Chromatic," "percy snapshot," "argos screenshot." Not for: bulk baseline regeneration after a redesign broke many tests — use selector-drift-recovery; cross-browser rendering matrices — use cross-browser-testing; general Playwright test structure — use playwright-automation. Related: playwright-automation, ci-cd-integration, cross-browser-testing.

日本語の概要は準備中です。原文の説明を表示しています。

Measure and improve test coverage meaningfully. Covers Istanbul/V8/coverage.py configuration, coverage gap analysis by risk, coverage-as-ratchet in CI (never let it decrease), PR coverage diff checks, mutation testing for assertion quality, and distinguishing meaningful from vanity coverage. Use when: "code coverage," "coverage gap," "Istanbul," "coverage threshold," "coverage report," "branch coverage." Not for: writing the tests that raise coverage — use unit-testing; coverage as a tracked KPI trend over time — use qa-metrics. Related: unit-testing, ci-cd-integration, qa-metrics, ai-qa-review.

日本語の概要は準備中です。原文の説明を表示しています。

Iterative rubric-based evaluation and self-improvement loop. Builds a scoring rubric interactively, evaluates an artifact with multiple models in parallel (Codex, Gemini, Claude), then autonomously improves the artifact one criterion at a time until a score threshold is met or circuit breaker fires. "/rulph", "rubric evaluate", "rubric score", "multi-model evaluate", "score and improve", "evaluate and iterate", "grade this", "루브릭 루프", "채점 루프", "자율 개선", "개선 루프", "루브릭 평가"

日本語の概要は準備中です。原文の説明を表示しています。

Calculates the WCAG 2.x contrast ratio between two colors, grades it against the AA and AAA thresholds for body text, large text and non-text UI parts, and finds the closest shade that passes. Use when someone asks to "check the contrast", "is this text readable on this background", "does our palette meet WCAG AA", "fix the low-contrast text", "audit the design tokens for accessibility", or brings a failed contrast finding from an audit. Handles hex and rgb() values, alpha, whole palettes, light and dark themes and a CI gate.

日本語の概要は準備中です。原文の説明を表示しています。

Restructure and optimize alert rules for monitoring platforms (Sentry, PagerDuty, Datadog, OpsGenie). Use when someone asks to "reduce alert noise", "fix alert fatigue", "create alert rules", "set up escalation policies", "tune alerting thresholds", or "create on-call runbooks". Generates platform-specific alert configurations and tiered escalation policies.

日本語の概要は準備中です。原文の説明を表示しています。

Run AI agent and LLM evaluations in CI/CD pipelines — automated quality gates that fail the build when AI output quality drops. Use when someone asks to "test my AI agent", "add evals to CI", "catch prompt regressions", "compare models", "evaluate LLM output quality", "set up AI quality gates", or "benchmark my agent before deploying". Covers eval frameworks (Cobalt, Promptfoo, Braintrust), LLM-as-judge scoring, threshold-based assertions, and GitHub Actions integration.

日本語の概要は準備中です。原文の説明を表示しています。

Google and Meta paid media account structure evaluation. Audits campaign/ad set architecture against conversion volume minimums, budget thresholds, and targeting overlap. Identifies over-segmentation, under-segmentation, budget fragmentation, and structural anti-patterns blocking algorithmic learning. Provides consolidation roadmaps with migration plans. Use when inheriting accounts, quarterly health checks, or before scaling budgets.

日本語の概要は準備中です。原文の説明を表示しています。

Refuses "flaky" as a diagnosis. Turns an intermittent failure into a reproduction by isolating it from the environment, naming the variable that controls it, forcing that variable, and measuring before and after with enough runs to count. Separates real defects from environment contention with evidence, and never retries to green or widens a threshold. Use when a test, performance check, or deploy step fails intermittently or passes on rerun.

日本語の概要は準備中です。原文の説明を表示しています。

Comprehensive truth scoring, code quality verification, and automatic rollback system with 0.95 accuracy threshold for ensuring high-quality agent outputs and codebase reliability.

日本語の概要は準備中です。原文の説明を表示しています。

Conduct deep OSINT research on individuals. Build full digital footprint, psychoprofile (MBTI/Big Five), career history, social graph with confidence scores. Recursive self-evaluation until completeness threshold is met. Includes internal intelligence (Telegram history, email, vault contacts) before going external. Use when: "osint", "досье", "research person", "find everything about", "пробей", "разведка", "due diligence", "background check", "digital footprint", "найди всё про", "собери информацию", "кто это", "профиль человека". NOT for: company/product research without a named person, competitive analysis, market research, content generation, or general web scraping tasks.

日本語の概要は準備中です。原文の説明を表示しています。