「ker」の検索結果

Use NVIDIA Maxine / NVIDIA AI for Media audio effects for speech cleanup and enhancement in live or offline media pipelines, including Background Noise Removal, denoise+dereverb, room echo removal, acoustic echo cancellation, audio super-resolution, Studio Voice, Speaker Focus, and Voice Font. Use when selecting, integrating, prompting around, QAing, or privacy-reviewing NVIDIA AFX SDK or BNR NIM workflows for conferencing, broadcast, podcast, avatar, ad, social, and video post-production audio.

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Provider-independent production workflow for recutting long talking-head, podcast, interview, webinar, panel, lecture, livestream, founder call, or customer-call footage into short clips, highlight reels, trailers, audiograms, captioned vertical videos, and social cutdowns. Use when an agent must ingest source recordings, transcribe and diarize speakers, select quotes without misrepresentation, preserve context, handle consent/rights/disclosures, clean jump cuts and audio, add captions, graphics, lower thirds, b-roll, platform variants, synthetic-media boundaries, review packets, delivery specs, and recut QA.

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Provider-independent media quality control and delivery direction for generated images, video, audio, ads, product content, social clips, broadcast and streaming assets, localization packages, and mixed-source edits. Use when an agent must define final export specs, inspect technical and perceptual quality, check captions/audio/color/accessibility/provenance/rights, create delivery sheets, version filenames, checksums, manifests, package deliverables, set acceptance or rejection criteria, and perform final delivery QA before handoff to a platform, broadcaster, streamer, client, or ad trafficker.

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Predict protein-coding genes in eukaryotic genomes using BRAKER3 for combined RNA-seq and protein evidence, or GALBA for protein-only evidence. Runs Augustus with trained parameters for accurate gene models. Use when annotating a newly assembled eukaryotic genome or improving existing gene predictions.

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Differential abundance and state analysis for cytometry data. Compare cell populations between conditions using statistical methods. Use when testing for significant changes in cell frequencies or marker expression between groups.

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Plot per-group distributions of continuous data using boxplots, violins, beeswarms, quasirandom jitter, and raincloud plots with sample-size honesty (Weissgerber 2015), KDE-bandwidth awareness, and N-aware encoding choices. Use when comparing distributions across a small number of groups — expression per cluster, biomarker per arm, scores per condition — and the bar-of-mean default is misleading.

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Detect single-nucleotide crosslink (CL) sites in CLIP-seq data using truncation patterns (iCLIP/eCLIP CITS), crosslink-induced mutations (HITS-CLIP CIMS deletions, PAR-CLIP T-to-C), or HMM/kernel-density methods (PureCLIP, PARalyzer, CTK). Use when single-nucleotide resolution is required for motif registration (mCross), allele-specific binding (BEAPR), variant-effect prediction, or comparing crosslink chemistry across CLIP variants.

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End-to-end ChIP-seq workflow from FASTQ files to annotated peaks. Covers QC, alignment, peak calling with MACS3 (or HOMER), and peak annotation with ChIPseeker. Use when processing ChIP-seq data from alignment through peak annotation.

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Visualizes ChIP-seq data using deepTools (computeMatrix, plotHeatmap, plotProfile, bamCoverage, bamCompare), pyGenomeTracks (modern INI-driven track plots), Gviz (R browser-style), EnrichedHeatmap (ComplexHeatmap-based), ChIPseeker tag heatmaps, and IGV batch screenshots. Handles bigWig normalization choices (CPM, BPM, RPGC, spike-in scaled), bamCompare operations (log2 ratio, subtract, SES), k-means clustering of heatmaps for biological subgrouping, and spike-in-scaled tracks for global-shift experiments. Use when generating publication-quality ChIP-seq signal heatmaps, profile plots, genome-browser tracks, or comparing samples visually.

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Annotate CLIP-seq peaks or crosslink sites to RNA features (5'UTR, CDS, 3'UTR, intron, splice junction, snoRNA, tRNA, ncRNA, repeat elements) with ChIPseeker, RCAS, RBP-Maps (Yeo splicing regulatory maps), and bedtools, applying feature-priority hierarchies, transcript-context resolution, and metagene aggregation. Use when characterizing where in transcripts an RBP binds, comparing peak distribution across regions, generating splicing-regulatory maps relative to alternative-splicing events, or distinguishing exonic vs intronic vs UTR binding.

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Applies ACMG/AMP 2015 framework with ClinGen SVI specifications, Tavtigian 2018/2020 Bayesian point system, Abou Tayoun 2018 PVS1 decision tree, Pejaver 2022 calibrated PP3/BP4 thresholds for REVEL/BayesDel/AlphaMissense, Brnich 2020 PS3/BS3 OddsPath, Walker 2023 SpliceAI splicing framework, and AMP/ASCO/CAP 2017 tumor tiers. Use when classifying germline variants P / LP / VUS / LB / B, applying VCEP-specific CSpec rules, computing Whiffin BS1, or assigning cancer Tier I-IV per Li 2017.

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Workflow for predictive modeling, biomarker discovery, survival modeling, and explainability over omics-derived features.

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Prepare for sales conversations with comprehensive account intelligence — company news, hiring signals, product launches, social activity, and decision-maker profiles. Combines firmographic data, news monitoring, and social signals for sales-ready briefings.

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Research any topic across the last 30 days using Reddit, Twitter, YouTube, Hacker News, web search, and news sources through SandBase. Use when asked for recent trends, launch reactions, competitor activity, person/company profiles, or current event analysis.

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Track flight status, delays, gate changes, and estimated arrival times for any commercial flight. Covers real-time flight tracking, schedule lookup, and delay monitoring for travel coordination and logistics planning.

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Track real-time events, announcements, and breaking developments across Twitter, Reddit, news outlets, and web search. Monitors event progression, public reaction, key moments, and aftermath coverage for crisis response and opportunity detection.

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Track hashtag performance across Instagram, TikTok, Twitter, and Xiaohongshu simultaneously. Monitors post volume, engagement rates, top contributors, and content patterns for campaign tracking, trend research, and community activation measurement.

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Research public companies and listed securities with current market, company, ownership, and filing data through SandBase. Use for ticker analysis, price-performance comparisons, insider activity, or an evidence-backed investment research brief; do not use for trade execution or personalized financial advice.

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Use when changing REPL clear/reset/resume/surface behavior (onClearTerminal, transcriptSeq remount, Ink Static paths, Ctrl+O/Ctrl+E transitions). Enforces single-owner reset transaction and prevents black-screen/flicker/duplicate-row regressions.

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Implements Manus-style file-based planning to organize and track progress on complex tasks. Creates task_plan.md, findings.md, and progress.md. Use when asked to plan out, break down, or organize a multi-step project, research task, or any work requiring >5 tool calls. Supports automatic session recovery after /clear.

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Use when a devopsdays event has finished and the slides or video recordings need to be attached to the talk pages, or when a speaker sends a link to their deck afterwards.

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Set up and deploy a Boundless prover to a GPU server using Ansible. Handles inventory setup, SSH connectivity, NVIDIA drivers, Docker, and the full bento stack. Use when deploying a new prover, redeploying to an existing server, or troubleshooting prover infrastructure.

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Build Spring Boot 4.x applications following the best practices. Use this skill: * When developing Spring Boot applications using Spring MVC, Spring Data JPA, Spring Modulith, Spring Security * To create recommended Spring Boot package structure * To implement REST APIs, entities/repositories, service layer, modular monoliths * To use Thymeleaf view templates for building web applications * To write tests for REST APIs and Web applications * To write ArchUnit tests for testing architecture * To configure the recommended plugins and configurations to improve code quality, and testing while using Maven. * To use Spring Boot's Docker Compose support for local development * To create Taskfile for easier execution of common tasks while working with a Spring Boot application

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Test application security against OWASP Top 10 (2025) with automated CI tooling: OWASP ZAP (DAST), dependency/supply-chain scanning (OSV-Scanner, SBOM, provenance), Semgrep SAST, auth/session tests (JWT, OAuth, RBAC), and XSS/CSRF/SQLi/SSRF Playwright patterns. Use when: "security test," "OWASP," "vulnerability," "ZAP," "XSS," "SSRF," "dependency scan," "auth testing," "OWASP LLM Top 10." Scope is automated scanning + negative-path security tests in CI, not manual penetration testing. Not for: mapping security controls to regulations (SOC 2, HIPAA, PCI, GDPR) — use compliance-testing; pipeline stage wiring and deploy gating mechanics — use ci-cd-integration; purely functional API auth/input tests with no attacker model — see api-testing; testing your product's own LLM features or defending the agent itself (prompt-injection detector, indirect injection, jailbreak red-teaming) — use ai-system-testing. Related: ci-cd-integration, compliance-testing, api-testing, shift-left-testing, ai-system-testing.

日本語の概要は準備中です。原文の説明を表示しています。