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概要と使いどころ
Full Jira ticket context analysis via the jira-analyst agent — including media (attached images / PDFs / screenshots) and linked issues. Produces structured findings suitable for posting back as a Jira comment. Read-only. Triggers: 'analyze KEY', 'rca for KEY', 'describe KEY with media'. NOT for complexity scoring (mk:jira-evaluator); NOT for story-point estimation (mk:jira-estimator).
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Structured second-pass reasoning after code review or plan evaluation. Offers named reasoning methods (pre-mortem, inversion, red team, Socratic, etc.) to re-examine findings through a specific lens. Use after /mk:review verdict or any time deeper analysis is needed on an existing output. NOT for initial review (see mk:review); NOT for creating implementation plans (see mk:plan-creator).
日本語の概要は準備中です。原文の説明を表示しています。
Analyze external URL to evaluate fit with oh-my-customcode project and auto-create GitHub issue with verdict
日本語の概要は準備中です。原文の説明を表示しています。
Prevent session idle during background agent work via SubagentStop prompt hook auto-continuation
日本語の概要は準備中です。原文の説明を表示しています。
Structured SE task evaluation using 15 benchmark definitions from claude-code-harness research
日本語の概要は準備中です。原文の説明を表示しています。
Adversarial code review using attacker mindset — trust boundary, attack surface, business logic, and defense evaluation
日本語の概要は準備中です。原文の説明を表示しています。
Spin up a working LiveAvatar demo from a curated catalog — clones the reference repo, installs dependencies, provisions the LiveAvatar account, and fills the env file, then hands off the parts only a human can do. Use when: (1) User wants to try, test, see, or demo LiveAvatar, (2) User asks what LiveAvatar demos or examples exist, (3) User wants a sales agent / lead-qualification avatar, (4) User wants a LiveKit agent driving a LiveAvatar avatar, (5) User wants an avatar joining their own LiveKit room, (6) User wants a speech-to-speech avatar, a GPT-Live demo, a language-learning or tutor avatar, a customer-support avatar, a poker coach / game-style avatar, or an avatar with on-screen visuals/overlays, (7) User says "run the LiveAvatar demo", "show me LiveAvatar", "get me started with LiveAvatar", or "clone the LiveAvatar example", (8) User is evaluating LiveAvatar and wants something running before writing their own integration.
日本語の概要は準備中です。原文の説明を表示しています。
Audit whether a declared local review evaluation can support fair quality claims. Use only when the user explicitly asks to audit review-eval validity or use the bundled synthetic fixture.
日本語の概要は準備中です。原文の説明を表示しています。
Use this skill for ANY of the following — do not skip it even if the query seems simple: strategic decisions, business analysis, thesis building, complex problem solving, geopolitical analysis (non-market), philosophical reasoning, academic research, system design, decision under uncertainty, long-form thinking, or any question that benefits from First Principle deconstruction and multi-agent reasoning. ALWAYS use this skill when the user asks about: why something works the way it does, whether a decision is correct, how to think about a complex problem, what could go wrong, analyzing a situation from multiple angles, or any "should I..." question involving real-world trade-offs. This is NOT a market/trading skill — for financial markets, BTC, gold, stocks, forex, macro economics, use money-atlas-intelligence-os instead.
日本語の概要は準備中です。原文の説明を表示しています。
Fallback for general coding work that does not match any specific sextant sub-skill. Use for lightweight tasks: config changes, style fixes, utility functions, one-off scripts, or tasks too small to warrant a dedicated workflow. All dedicated sub-skills take priority over this one — check these first: sextant:fix-bug (broken behavior), sextant:debug (unknown bug location), sextant:add-feature (new functionality), sextant:modify-feature (changing existing behavior), sextant:review-code (evaluating code), sextant:write-tests (test coverage), sextant:refine-requirements (ambiguous scope), sextant:plan (multi-step sequencing), sextant:ship (release prep), sextant:migrate (cross-module upgrade), sextant:security (vulnerability audit). Only use this skill when none of the above match.
日本語の概要は準備中です。原文の説明を表示しています。
Use when user says "simmer this", "refine this", "hone this", "iterate on this", or asks to improve a specific artifact over multiple rounds. Runs an iterative refinement loop with investigation-first judges that read the code, understand the problem, and propose evidence-based improvements. Auto-selects single judge or multi-judge board based on complexity. Works on any artifact type: documents, prompts, specs, emails, creative writing, API designs, pipelines, codebases. Supports multi-file workspace targets, runnable evaluators, and open-ended optimization (model selection, pipeline topology, prompt tuning).
日本語の概要は準備中です。原文の説明を表示しています。
Setup subskill for simmer. Inspects the artifact or workspace, infers evaluation contracts and search space, proposes a complete assessment to the user, and produces a setup brief after confirmation. Conversational, not form-based — the agent does the work of understanding the problem, then presents what it found. Do not invoke directly — called by simmer orchestrator.
日本語の概要は準備中です。原文の説明を表示しています。
Italian geographic and property data through Openapi - geocoding/reverse geocoding, zip codes (CAP), municipalities/provinces/regions with ISTAT codes, Italian cadastre (catasto) property and owner lookups, visure catastali/ipotecarie, real estate valuations.
日本語の概要は準備中です。原文の説明を表示しています。
Research complex questions and synthesize relevant evidence into a clear, cited answer. Useful for competitive and market analysis, company research, prospect discovery, enrichment, historical comparisons, and evaluating conflicting claims. Adapt the depth and format to the question; use when a focused search or single-page read is insufficient.
日本語の概要は準備中です。原文の説明を表示しています。
Runnable end-to-end validation playbook for the Rembric TUI installer — catch breakage before merging/deploying, AND a sandboxed manual walkthrough to evaluate/iterate its UI/UX without polluting your real env. Apply before shipping any change touching `apps/plugin/install.sh`, the repo-root `install.sh` shim, any per-client `install.sh`/`uninstall.sh`, or distribution docs, or when you want to preview/try/demo the installer and polish how it looks and feels. Layered: CI-safe headless (vitest + `sh -n`), local install round-trips, operator interactive pty smoke, an optional full Docker `up` smoke, plus a sandboxed manual UX walkthrough. For the installer contract/what-not-to-break, see `rembric-tui-installer`.
日本語の概要は準備中です。原文の説明を表示しています。
Infer gene regulatory networks from bulk or general expression data with mutual-information (ARACNe) and tree-ensemble (GENIE3, GRNBoost2) methods, and infer transcription-factor protein activity from regulons with VIPER and msVIPER. Covers the activity-not-edges paradigm, the undirected-association caveat, the DREAM5 wisdom-of-crowds and method-complementarity result, AUPRC-over-AUROC evaluation, and gold-standard incompleteness. Use when inferring a regulatory network from a bulk expression matrix, finding master regulators, or scoring TF activity from a signature. For single-cell motif-pruned regulons see scenic-regulons; for co-expression modules see coexpression-networks.
日本語の概要は準備中です。原文の説明を表示しています。
Aligns and QCs methylated-RNA-immunoprecipitation (MeRIP / m6A-seq) IP and input libraries using STAR or HISAT2 splice-aware mapping, samtools sort/index, IP/input matched-pair tracking, antibody-lot metadata recording, replicate concordance via deepTools multiBamSummary + plotCorrelation, IP enrichment QC via plotFingerprint and per-transcript IP/input ratio distributions, library-complexity saturation curves via PreSeq, and the explicit do-NOT-deduplicate convention for standard non-UMI MeRIP. Use when preparing paired IP and input BAM files for exomePeak2 / MeTPeak / MACS3 peak calling, evaluating MeRIP replicate concordance and IP enrichment, deciding whether to deduplicate (standard MeRIP typically NOT), choosing genome-vs-transcriptome alignment for downstream peak vs m6Anet workflows, recording antibody clone and lot metadata for cross-batch reconciliation, detecting failed IPs via saturation curves and IP/input distribution shape, or generating IP-over-Input bigWig tracks for visualisation.
日本語の概要は準備中です。原文の説明を表示しています。
Build publication-quality figures in R with ggplot2 using the grammar of graphics (data + aesthetics + geometries + scales + facets + themes) with CVD-safe palettes, cairo_pdf TrueType embedding, programmatic aes via tidy evaluation, and the theme_classic publication baseline. Use when producing static figures in R for papers, presentations, or reports.
日本語の概要は準備中です。原文の説明を表示しています。
Predict RBP binding from RNA sequence using deep learning models (RBPNet sequence-to-signal, RNAProt RNN, GraphProt2 GCN with structure, DeepCLIP, DeepRiPe multi-modal CNN) for variant-effect prediction, in silico binding-site discovery, model interpretation, and transfer learning from CLIP and RBNS datasets. Use when computational prediction of RBP binding from sequence is needed, evaluating variant effects on binding without further wet-lab experiments, comparing model performance, or training a custom model on ENCODE eCLIP data.
日本語の概要は準備中です。原文の説明を表示しています。
Compute genome-to-genome distances (ANI, AAI, dDDH, k-mer Mash) and assign taxonomic classifications using skani (Shaw 2023), FastANI (Jain 2018), pyani / pyANI ANIb / ANIm, OrthoANI (Lee 2016), AAI (amino-acid identity), dDDH via TYGS / GGDC, GTDB-Tk (Chaumeil 2020 standard prokaryote taxonomy), and Mash MinHash (Ondov 2016). Use when delineating prokaryote species (95% ANI threshold; Jain 2018 Nat Commun 9:5114), assigning genomes to GTDB taxonomy with ANI radius, computing genome similarity matrices for clustering, classifying archaea, evaluating MAG (metagenome-assembled genome) species assignment, applying skani for fast metagenomic ANI screening, or reconciling 16S rRNA-based taxonomy with whole-genome ANI.
日本語の概要は準備中です。原文の説明を表示しています。
Estimate causal effects of an exposure on an outcome from GWAS summary statistics using genetic instruments. Implements IVW (fixed/random), MR-Egger, weighted median/mode, MR-RAPS, CAUSE, GSMR-HEIDI, MR-PRESSO, MVMR, MR-Clust, LCV, and LHC-MR via TwoSampleMR, MendelianRandomization, MR-PRESSO, cause, and lhcMR. Use when testing causal direction between traits, evaluating drug-target effects via cis-pQTL/cis-eQTL, performing multivariable mediation MR, distinguishing causation from correlated horizontal pleiotropy, or producing STROBE-MR-compliant sensitivity batteries.
日本語の概要は準備中です。原文の説明を表示しています。
Fits structural equation models to GWAS summary statistics using GenomicSEM (Grotzinger 2019), including common-factor models, confirmatory factor models, ESEM, common-factor GWAS with Q_SNP heterogeneity, multivariate Wald tests, and stratified GenomicSEM partitioned heritability. Reconciles results against MTAG multi-trait analysis. Handles sample overlap via the LDSC sampling-covariance matrix, identifies and resolves Heywood cases, and verifies model fit with CFI / RMSEA. Use when modeling latent genetic architecture across correlated traits, running multivariate GWAS on a shared factor, distinguishing factor-mediated from trait-specific SNP effects, or comparing GenomicSEM common-factor results against MTAG when both depend on accurate sampling covariance.
日本語の概要は準備中です。原文の説明を表示しています。
Calculates tumor mutational burden from WES/WGS/panel data with Friends of Cancer Research harmonization equations, per-assay calibration (FDA 10/Mb = 7.8 TSO500 = 8.4 OncomineTML), synonymous/indel/germline filtering, hypermutator tiering, blood TMB, and integration with HLA-LOH and neoantigen quality (Luksza 2017 fitness). Use when assessing ICI eligibility under tumor-specific cutoffs (McGrail 2021), comparing tissue vs bTMB, or auditing TMB-H reporting against ESMO 2024 and FDA pembrolizumab pan-tumor 2020.
日本語の概要は準備中です。原文の説明を表示しています。
Create irresistible offers and pitches using Alex Hormozi's methodology from $100M Offers. Guides through value equation, guarantee frameworks, pricing psychology, and creating offers "too good not to take" for any product or service.
日本語の概要は準備中です。原文の説明を表示しています。