「direction」の検索結果

Simulate transcription factor perturbation effects on cell state in silico with CellOracle and Dynamo, and predict transcriptional responses to genetic perturbations with GEARS, scGen, and CPA. Covers the direction-not-magnitude principle, local-linear validity, the GRN/velocity error it inherits, baseline discipline (mean and additive baselines), and the validation gap. Use when predicting TF knockout or overexpression effects, ranking driver TFs for fate transitions, or planning perturbation experiments. For GRN construction see multiomics-grn; for experimental Perturb-seq see single-cell/perturb-seq.

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Infer transcription factor regulons from single-cell RNA-seq with pySCENIC by combining GRNBoost2 co-expression, cisTarget motif-enrichment pruning, and AUCell per-cell activity scoring. Covers the motif-pruning-as-directionality principle, regulon specificity scoring, run-to-run stability, and database/species matching. Use when identifying TF regulons, scoring TF activity per cell, finding master regulators of cell identity, or comparing regulon activity across conditions. For enhancer-driven multiomic GRNs see multiomics-grn; for bulk inference and VIPER protein-activity see grn-inference.

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Estimate causal effects of an exposure on an outcome from GWAS summary statistics using genetic instruments. Implements IVW (fixed/random), MR-Egger, weighted median/mode, MR-RAPS, CAUSE, GSMR-HEIDI, MR-PRESSO, MVMR, MR-Clust, LCV, and LHC-MR via TwoSampleMR, MendelianRandomization, MR-PRESSO, cause, and lhcMR. Use when testing causal direction between traits, evaluating drug-target effects via cis-pQTL/cis-eQTL, performing multivariable mediation MR, distinguishing causation from correlated horizontal pleiotropy, or producing STROBE-MR-compliant sensitivity batteries.

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Use when implementing location services, maps, geofencing, or debugging location/MapKit issues. Covers Core Location, CLMonitor, MapKit, annotations, directions.

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Implements keyboard, directional, and scene-level focus behavior across SwiftUI and UIKit. Use when managing @FocusState, defaultFocus, focused values, focusable interactions, focus sections, tvOS geometric focus and Siri Remote navigation, watchOS Digital Crown input, visionOS connected-device focus versus gaze hover/input targets, macOS key view loop and Full Keyboard Access, focus restoration after presentation changes, custom focus routing with UIFocusGuide, or debugging focus with UIFocusDebugger.

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Guide for implementing smooth, native-feeling animations using React's View Transition API (`<ViewTransition>` component, `addTransitionType`, and CSS view transition pseudo-elements). Use this skill whenever the user wants to add page transitions, animate route changes, create shared element animations, animate enter/exit of components, animate list reorder, implement directional (forward/back) navigation animations, or integrate view transitions in Next.js. Also use when the user mentions view transitions, `startViewTransition`, `ViewTransition`, transition types, or asks about animating between UI states in React without third-party animation libraries.

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Guidance for distinctive, intentional visual design when building new UI or reshaping an existing one. Helps with aesthetic direction, typography, and making choices that don't read as templated defaults.

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Wilkinson, branchline, ratrace, directional couplers, corporate dividers, Rotman lenses for power splitting and beam-forming. TRIGGER: user asks to design, create, or analyze any coupler, splitter, power divider, combiner, or Rotman lens. Invoke BEFORE writing code — class names and design() availability vary per coupler type. SKIP: EM simulation/S-parameter extraction of an existing component (use matlab-analyze-em), building custom non-catalog geometry (use matlab-assemble-pcb-layout), material/stackup setup only (use matlab-manage-pcb-material), cascading multiple components (use matlab-integrate-pcb-circuit).

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Create or update implementation plans in the repo's SIMPLE or COMPLEX format. Use when turning an idea, PRD, or approved direction into a saved plan artifact.

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Cross-platform PPC strategy planner for ecommerce businesses. Analyzes your product and margins, recommends the right advertising platforms (Google Ads, Meta Ads, TikTok Ads), calculates ROAS targets, allocates budget across channels, and generates platform-specific campaign briefs with ad copy and creative direction. Two modes: (A) Build — design a multi-platform ad strategy from scratch, (B) Optimize — audit existing cross-platform campaigns and reallocate budget. Works for Shopify, WooCommerce, standalone stores, and marketplace sellers expanding to external traffic. No API key required.

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Full-stack e-commerce marketing strategy builder. Analyzes your product, market, and competitors, then builds a complete omnichannel marketing plan covering paid ads, SEO, email/SMS, content marketing, social media, influencer partnerships, and referral programs. Includes target audience persona, competitive landscape, channel prioritization with budget allocation, content direction, and a 90-day action plan. Works for any e-commerce platform — Shopify, Amazon, Etsy, WooCommerce, TikTok Shop, and more. No API key required.

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Use when users need to implement, integrate, debug, build, deploy, or validate a Web frontend after the product direction is already clear, especially for React, Vue, Vite, browser flows, or CloudBase Web integration.

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Use when users need visual direction, interface hierarchy, layout decisions, design specifications, or prototypes before implementing a Web or mini program UI.

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Save the current business state to disk so future Claude Code sessions can pick up where you left off. Captures confirmed conclusions, ruled-out directions, open hypotheses, and the next recommended skill. Use when the user has just reached a conclusion in /money-discover, /money-strategy, /money-diagnose, or any pipeline phase, and wants to lock the state in. Also triggered by: 'save this', 'checkpoint', 'remember this', 'lock it in', '保存', '存档', '记下来', '这个结论留着'.

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Detect quality and efficiency regressions over time using Agent Monitor data — rising error rate (APIError events), falling cache hit rate, growing compaction frequency, and climbing cost-per-session. Splits history into an earlier baseline window and a recent window and reports which metrics are getting worse, by how much, and where. Use when checking whether things are degrading or trending in the wrong direction.

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Use when changing an existing ChatGPT pet or Codex pet sprite sheet with Scenario: fixing a broken row, frame, jump or edge, regenerating one animation state, adding the sixteen look directions to a 1536x1872 v1 sheet, giving the pet a new outfit, color or accessory, renaming it in its pet.json, or checking a pet sheet and previewing it as an animated GIF.

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Use when creating a ChatGPT pet or Codex pet with Scenario: hatching an animated companion from a text idea, a character, mascot or brand cue, or reference photos and art; making the 1536x2288 v2 pet sprite sheet with nine animation states and sixteen look directions, the 1536x1872 v1 sheet ChatGPT web uploads, a pixel-perfect pixel-art pet, an animated GIF of the pet, or a Codex pet.json package.

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Use when turning a script or story into previs, layout, storyboards or an animatic in Blender: beats to shot list, camera and lens per shot, staging, camera height, 180-degree rule, screen direction, shot sizes, when to cut, camera moves, timing stills in the Video Sequencer, markers bound to cameras, Story Tools, Grease Pencil or 2D/3D hybrid boards. Also when an animatic shows the wrong frame, blocking keys are not stepped, Rigify operators are missing, or viewport render fails headless.

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Use when animating 2D game art with Scenario: walk, idle or attack cycles in 4 or 8 directions, isometric sprite sheets, animated GIFs, frame-by-frame pixel art animation, VFX loops such as fire or smoke, looping a sprite seamlessly, animating an existing character image, a full animation sheet from one prompt, extracting animation frames from a generated video, or slicing a sprite sheet into engine-ready frames for Unity, Godot, or Unreal. Keywords: spritesheet, keyframes, frame grid, GIF.

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Triage an outage, loss of stakeholder trust or a failing engagement direction. Use for urgent recovery; distinguish diagnosis from authorized production mitigation.

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Build a multi-quarter roadmap from a backlog of ideas, requests, and ongoing initiatives. Use this skill when planning the next quarter, sequencing dependent work, balancing build vs improve vs maintain, or making the case for what NOT to do. Triggers on roadmap, quarterly planning, what should we build next, sequencing, prioritization, OKR planning, capacity planning, what's on the roadmap, plan the year, what to ship next quarter. Also triggers when stakeholders are pulling in different directions and the team needs a defensible plan.

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Turning research artifacts into actionable PM insight. Customer interviews, user research notes, support ticket reviews, sales call transcripts, survey data, in-app feedback, all synthesized into the decisions they are meant to inform. The discipline of moving from raw discovery data to clear product direction without losing signal in the synthesis or fabricating insight that was not actually there. Triggers on research synthesis, customer interview synthesis, user research analysis, discovery readout, research insights, sales call analysis, support ticket analysis, qualitative data analysis. Also triggers when a team has done research but cannot turn it into decisions, when synthesis is producing pretty decks but no roadmap movement, or when an upcoming PM decision needs to be grounded in research already conducted.

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Collect and persist structured presentation requirements for Codex Slides, including scenario choice, audience, page count, language, format, research mode, visual direction, source-file roles, and clarification checkpoints. Use when a new deck request is ambiguous or scenario-led.

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Builds real-time communication systems with WebSockets or Socket.IO including bidirectional messaging, horizontal scaling with Redis, presence tracking, and room management.

日本語の概要は準備中です。原文の説明を表示しています。