Estimate causal effects from observational and experimental data — DAGs, confounding control, quasi-experimental designs, and sensitivity analysis. Use when you need "what causes what," not just correlation.
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概要と使いどころ
Estimate causal effects from observational and experimental data — DAGs, confounding control, quasi-experimental designs, and sensitivity analysis. Use when you need "what causes what," not just correlation.
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Audit ML experiment tracking infrastructure for reproducibility gaps, parameter logging completeness, metric capture, artifact management, and pipeline orchestration. Covers MLflow, Weights and Biases, DVC, Sacred, Neptune, Hydra configs, model registries, and produces a reproducibility scorecard (0-30) with actionable fixes for data science teams.
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Build Opportunity Solution Trees using Teresa Torres' framework for structured product discovery. Use this skill when: - You need to map a desired outcome to opportunities, solutions, and experiments - You want to decide WHAT to build next based on user research and discovery data - You have workshop findings, pilot feedback, or user research to structure into actionable options - You need a visual tree diagram showing the path from outcome to testable experiments
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Runs autonomous keep/discard experiments on a codebase to optimize a single metric for a fixed duration, in the style of karpathy/autoresearch. Use when the user says "autoresearch" (optionally with a focus, e.g. "autoresearch the optimizer"), asks to run experiments on a repo overnight, to hill-climb or optimize a metric autonomously, or points at a repo with a karpathy-style program.md.
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Use for experiment discipline recipes when optimizing a Coworld player.
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Use for Crewrift-specific experiment discipline recipes when optimizing a player.
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Use for reusable experiment discipline recipes in software and coding-agent work.
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Use for experiment discipline recipes in scripted Coworld policy optimization.
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Scientific research engine for hypothesis testing, literature gap analysis, experimental validation, and data-driven discovery. Enforces adversarial review (Reviewer 2), 32 quality gates, tree search over hypotheses, confounder harness for quantitative claims, and serendipity detection. TRIGGER when: user asks to analyze scientific data, test hypotheses, validate findings, search for research gaps, design experiments, or investigate results. DO NOT TRIGGER when: pure code review, documentation writing, devops tasks, general conversation, or non-scientific data transformation.
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Reference when designing autonomous agent systems or deciding agent freedom/safety/context management/collaboration infrastructure. 10 design principles distilled from Karpathy autoresearch (autonomous ML experiment loop) + AgentHub (agent-native Git DAG). Triggered by "autoresearch", "agenthub", "ratchet" ("래칫"), "context budget", "dumb platform", "program.md", "overnight", "autonomous experiment" ("자율 실험"), "branchless", "single-file constraint" ("단일 파일 제약"), "fixed time budget" ("고정 시간 예산") keywords.
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Causal inference with treatment/control groups over time. Use when user mentions: treatment effects, policy evaluation, pre/post comparison, parallel trends, DID, DiD, difference in differences, natural experiment, quasi-experimental.
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Benchmark multi-agent coordination systems with experiment design, power analysis, human rating protocols, bootstrap confidence intervals, and reproducible reporting. Use for salvage latency, recovery fidelity, coordination overhead, and protocol comparison studies. NOT for ML model benchmarking, web-product A/B testing, survey design, or general-purpose data science.
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Simulate transcription factor perturbation effects on cell state in silico with CellOracle and Dynamo, and predict transcriptional responses to genetic perturbations with GEARS, scGen, and CPA. Covers the direction-not-magnitude principle, local-linear validity, the GRN/velocity error it inherits, baseline discipline (mean and additive baselines), and the validation gap. Use when predicting TF knockout or overexpression effects, ranking driver TFs for fate transitions, or planning perturbation experiments. For GRN construction see multiomics-grn; for experimental Perturb-seq see single-cell/perturb-seq.
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Stores and operates on sparse expression matrices for single-cell and large bulk RNA-seq, covering dgCMatrix/dgRMatrix/dgTMatrix when-each-is-fast, the dgCMatrix (CSC, R) <-> CSR (Python) implicit transpose, AnnData (cells-rows) <-> SingleCellExperiment (cells-cols) orientation flip, HDF5/h5ad vs Zarr cloud-native shift, HDF5SummarizedExperiment + DelayedArray for out-of-memory bulk, scanpy backed mode for large h5ad, the ~10-15% density crossover where dense beats sparse, 10X format proliferation (MTX vs CellRanger H5 vs h5ad), the dense-conversion memory blow-up, and Dask + Zarr for consortium-scale matrices. Use when choosing sparse format, working with single-cell-sized matrices, importing/exporting 10X, debugging R/Python interop transposes, processing matrices too large for RAM, or building cloud-native pipelines.
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Search scientific papers via the BGPT MCP server and retrieve structured experimental data — methods, results, conclusions, quality scores, and 25+ metadata fields per paper.
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Guidance for SPR and BLI binding characterization experiments. Use when: (1) Planning binding kinetics experiments, (2) Troubleshooting poor/no binding signal, (3) Interpreting kinetic data artifacts, (4) Choosing between SPR vs BLI platforms.
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Search scientific papers and retrieve structured experimental data extracted from full-text studies via the BGPT MCP server. Returns 25+ fields per paper including methods, results, sample sizes, quality scores, and conclusions. Use for literature reviews, evidence synthesis, and finding experimental details not available in abstracts alone.
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Autonomously improve a real artifact (code, training recipe, agent harness, data pipeline, prompt) against an objective and an evaluator, using Hypothesis Tree Refinement (HTR) from the Arbor paper. Use this whenever someone wants to iteratively optimize something over many experiments without overfitting — e.g. "get my model's eval score up", "improve this agent/harness", "tune this pipeline", "beat the baseline on this benchmark", "run a search over approaches and keep the best", "do an MLE-bench / Kaggle-style optimization", or any long-horizon "make this artifact better and don't just memorize the dev set" task. Trigger it even when the user doesn't say "Arbor" or "hypothesis tree" but describes repeated experiment-and-evaluate loops, branching exploration of competing ideas, or worries about a dev/test gap. Runs Claude itself as the coordinator with subagent executors in isolated git worktrees; for the standalone `arbor` CLI tool see references/arbor-upstream.md.
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Design leakage-safe machine learning experiments that mirror real deployment and support fair model comparisons. Use when defining prediction timing, feature eligibility, train-validation-test splits, baselines, metrics, or controlled model iterations; not for auditing whether raw labels are trustworthy.
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Quando o usuário quer planejar, projetar ou implementar um teste A/B ou experimento. Também use quando o usuário menciona "teste A/B", "split test", "experimento", "testar essa mudança", "copy variante", "teste multivariado" ou "hipótese". Para implementação de rastreamento, veja analytics-tracking.
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Visualize métricas de treinamento, depure modelos com histogramas, compare experimentos, visualize grafos de modelos e perfil de desempenho com TensorBoard - kit de visualização de ML do Google
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Rastreie experimentos de ML com logging automático, visualize treinamento em tempo real, otimize hiperparâmetros com sweeps e gerencie registro de modelos com W&B - plataforma colaborativa de MLOps
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Track Two / internal innovation system for running small, fast experiments outside the core business. Runs in three modes — Diagnostic for designing the full Protoloop from scratch (intake channels, loop structure, team, exit paths), Review for running the monthly heartbeat meeting (loop-by-loop decisions, forward-loading, portfolio health), and Alert Triggers for defining tripwires that protect, feed, and maintain momentum in the system. Updates company-context.md after every run. Triggers on questions about innovation pipelines, intrapreneurship, Track Two strategy, experimentation systems, handling ideas that don't fit the core business, or building systematic exploration alongside exploitation. Based on 20 years of practice by Eterdis (eterdis.com).
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When the user wants to plan, design, or implement an A/B test or experiment. Also use when the user mentions "A/B test," "split test," "experiment," "test this change," "variant copy," "multivariate test," "hypothesis," "should I test this," "which version is better," "test two versions," "statis...
日本語の概要は準備中です。原文の説明を表示しています。