「sample」の検索結果

Designs retrospective or prospective clinical cohort study protocols for biomedical and clinical research. Always use this skill when the user needs a cohort-based study plan rather than a general study idea, evidence summary, or mechanistic experiment design. Focus on cohort appropriateness, enrollment logic, baseline time-zero definition, follow-up structure, endpoint definition, variable collection, confounding control, and a coherent primary statistical analysis line. Do not invent data availability, follow-up completeness, outcome ascertainment quality, sample size adequacy, or causal interpretability.

日本語の概要は準備中です。原文の説明を表示しています。

Designs complete research plans that integrate clinical variables with multi-omics data from a user-provided biomedical direction. Always use this skill whenever a user wants to design, scope, or structure a study that combines clinical variables with transcriptomics, proteomics, metabolomics, epigenomics, or related omics layers for mechanism interpretation, biomarker development, risk stratification, treatment-response analysis, or translational use. It should define the clinical use case, alignment across data layers, feature-reduction and fusion logic, modeling route, mechanism-interpretation layer, validation ladder, and four workload configurations (Lite / Standard / Advanced / Publication+). Never fabricate datasets, accession numbers, sample counts, metadata completeness, platform coverage, literature references, PMIDs, DOIs, or validation status. Always include the mandatory Dataset Disclaimer immediately before any workflow section that mentions datasets or public resources.

日本語の概要は準備中です。原文の説明を表示しています。

Generates complete Mendelian randomization study designs from a user-provided exposure and outcome direction. Always use this skill whenever a user wants to design, plan, or build a Mendelian randomization study — even if phrased as "help me write a paper on X", "design an MR study for Y", or "I want to test whether A causally affects B using GWAS". Covers core two-sample MR design, optional bidirectional follow-up, optional multivariable MR, IV selection logic, ancestry alignment, harmonization, IVW as the default primary estimator, weighted median / MR-Egger / MR-PRESSO / leave-one-out sensitivity analyses, Steiger directionality, heterogeneity / pleiotropy checks, and explicit claim-boundary control. Always outputs four workload configs (Lite / Standard / Advanced / Publication+) with a recommended primary plan, stepwise workflow, method rationale, validation ladder, figure plan, minimal executable version, and strictly verified literature guidance with no fabricated references.

日本語の概要は準備中です。原文の説明を表示しています。

Designs a realistic, execution-aware biomedical study version under explicit constraints of samples, time, budget, data access, lab capacity, team skill, and validation resources. Always use this skill when the user has a real study idea, a candidate route, or a partially framed project but cannot assume ideal conditions. If critical feasibility inputs are missing, first clarify what resources are currently available, what resources may be obtainable, and what resources are realistically unavailable. Do not invent access, capabilities, collaborations, or validation resources. Focus first on feasibility-constrained study framing, route narrowing, dependency control, and minimum viable study design.

日本語の概要は準備中です。原文の説明を表示しています。

Quickly judges whether a biomedical paper is worth deep reading by screening for question fit, design quality, sample adequacy, methodological novelty, and reproducibility value.

日本語の概要は準備中です。原文の説明を表示しています。

Explains why studies on the same biomedical topic reach different or opposing conclusions by auditing differences in population, endpoint definition, sample source, assay or platform, study design, statistical model, adjustment strategy, validation chain, and bias control. It separates true contradiction from apparent contradiction caused by framing or methods. Never fabricate references, PMIDs, DOIs, trial identifiers, dataset details, platform details, study features, or conflict explanations that are not supported by the input.

日本語の概要は準備中です。原文の説明を表示しています。

Designs complete integrated research plans for bulk transcriptomics, proteomics, metabolomics, and related omics from a user-provided biomedical direction. Always use this skill whenever a user wants to design, scope, or structure a bulk multi-omics or single-omics-plus-clinical study — including disease-focused, mechanism-focused, biomarker-focused, stratification-oriented, or translational projects. It should define the research question, choose the best-fit study pattern, recommend example datasets as reference candidates only, specify the core analysis modules and method choices, propose a validation ladder, and output four workload configurations (Lite / Standard / Advanced / Publication+). Never fabricate datasets, accession numbers, sample counts, metadata completeness, cohort availability, assay coverage, literature references, PMIDs, DOIs, or validation status. Always include the mandatory Dataset Disclaimer immediately before any workflow section that mentions datasets or public resources.

日本語の概要は準備中です。原文の説明を表示しています。

Assesses whether study results are trustworthy by auditing design integrity, sample structure, statistical handling, bias control, validation chain, and claim discipline. It identifies where results are robust, fragile, overfit, under-validated, or overclaimed. Always separate reported findings from reliability judgment. Never fabricate references, PMIDs, DOIs, trial identifiers, study features, or validation claims.

日本語の概要は準備中です。原文の説明を表示しています。

Use when performing correlation analysis between two variables including Pearson and Spearman correlation methods. Supports command-line parameter input, automatic data format detection, parameter validation, result directory creation, and CSV or TXT format result export.

日本語の概要は準備中です。原文の説明を表示しています。

Use when building a weighted gene co-expression network from a bulk expression matrix and a sample group file, filtering variable genes by MAD, identifying co-expression modules with WGCNA, correlating modules with traits, and exporting module-level plots and gene tables. NOT for single-cell RNA-seq, differential expression testing, methylation analysis, or datasets that are too small for WGCNA after quality control.

日本語の概要は準備中です。原文の説明を表示しています。

Use when correcting batch effects in merged bulk expression matrices with sample-level batch metadata while preserving biological group structure and generating before-and-after QC plots. NOT for: single-cell integration, raw FASTQ processing, differential expression without batch labels, or datasets without biological groups.

日本語の概要は準備中です。原文の説明を表示しています。

Use when identifying stable sample subtypes from bulk expression matrices with ConsensusClusterPlus, including PAC-based model selection and consensus matrix/CDF visualization. NOT for: differential expression analysis, single-cell clustering workflows, or non-expression tables.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill to compute ESTIMATE immune-related microenvironment scores from a bulk expression matrix, generate an ESTIMATE score heatmap, and optionally generate group-wise ESTIMATE score boxplots plus significance tables when a sample group file is supplied. Trigger keywords: ESTIMATE, immune score, stromal score, tumor microenvironment score. NOT for: immune cell deconvolution, single-cell analysis, differential expression, clinical diagnosis.

日本語の概要は準備中です。原文の説明を表示しています。

Use this skill to run GSVA or ssGSEA pathway-level differential analysis from a bulk expression matrix and a sample group file, then generate a heatmap from the saved GSVA result object. Trigger keywords: GSVA, ssGSEA, pathway enrichment, KEGG pathway analysis, MSigDB. NOT for: gene-level differential expression, single-cell analysis, methylation analysis, clinical diagnosis.

日本語の概要は準備中です。原文の説明を表示しています。

Run immune pathway GSVA or ssGSEA analysis from a bulk expression matrix, a sample group file, and a local immune Reactome gene-set table, then export differential pathway results and a heatmap for two-group comparison.

日本語の概要は準備中です。原文の説明を表示しています。

Recommend suitable prompts from 10,000+ Nano Banana Pro image generation prompts based on user needs. Optimized for Nano Banana Pro (Gemini), but prompts also work with Nano Banana 2, Seedream 5.0, GPT Image 1.5, Midjourney, DALL-E, Flux, Stable Diffusion, and any text-to-image AI model. Use this skill when users want to: - Generate images with AI (any model — Nano Banana Pro, Gemini, GPT Image, Seedream, etc.) - Find proven AI image generation prompts and prompt templates - Get prompt recommendations for specific use cases (portraits, products, social media, posters, etc.) - Create illustrations for articles, videos, podcasts, or marketing content - Browse a curated prompt library with sample images - Translate and understand prompt techniques Also available: "ai-image-prompts" skill — a model-agnostic version of this library for universal image generation.

日本語の概要は準備中です。原文の説明を表示しています。

Lomb-Scargle periodogram for finding periodic signals in unevenly sampled time series data. Use when analyzing light curves, radial velocity data, or any astronomical time series to detect periodic variations. Works for stellar rotation, pulsation, eclipsing binaries, and general periodic phenomena. Based on lightkurve library.

日本語の概要は準備中です。原文の説明を表示しています。

Use BEFORE reading any data file that could be large (CSV/TSV, Parquet, HDF5, FITS, NetCDF, NDJSON, genomics FASTQ/FASTA/VCF/BAM, GRIB, ROOT, or big text/simulation logs like VASP OUTCAR). Returns a compact memory pointer — header/schema/shape/sample/key numbers — by introspection and sampling in bounded memory, so you never load a file bigger than the context window into the model. Reference data via the pointer; read specific ranges deterministically.

日本語の概要は準備中です。原文の説明を表示しています。

Scaffold and run a reproducible Monte Carlo simulation study in R — a declared assumption regime, a parameterized DGP, an estimator grid, a seeded replication loop, and a summary of bias, RMSE, empirical SE, coverage, size/power with Monte Carlo standard errors. Use when the user says "run a Monte Carlo simulation", "simulation study", "check the bias/coverage of an estimator", "compare estimators in simulation", "size and power simulation", "Monte Carlo experiment", or wants to demonstrate an estimator's finite-sample properties. Produces a numbered R script in `scripts/R/` and saves per-replication raw results + a summary table to `output/`.

日本語の概要は準備中です。原文の説明を表示しています。

Stress-test a finding against the choices you did not make. Enumerates the discrete forks a competent analyst could have taken (measure definition, sample filter, control set, clustering level, weighting, functional form), runs the specification grid, and reports the distribution rather than a point estimate — then attacks the identifying assumption with named, computable sensitivity statistics. Use when the user says "is this robust", "challenge this result", "specification curve", "multiverse", "how sensitive is this", "what if I'd used a different measure", "stress-test my estimate", or before a result becomes a headline claim. NOT a reviewer of prose or code — it challenges the CLAIM.

日本語の概要は準備中です。原文の説明を表示しています。

Analyze, recreate, align, and verify reference-video motion. Use when the user asks to recreate, copy, match, align, pixel-align, or compare a video; when a HyperFrames or Remotion remake is judged not aligned; when fixed reference playback and reusable motion components must be separated; or when delivery needs full-frame runtime, render, decode, boundary, timing, and archive evidence instead of sampled screenshots alone.

日本語の概要は準備中です。原文の説明を表示しています。

Capture a user's real writing voice from 5-20 prior samples, store a local voice.yaml fingerprint, and enforce it on newsjack drafts so AI tells disappear. Measures voice with named stylometry lenses (Burrows's Delta function-word vector, MATTR lexical diversity, sentence-length burstiness, Biber Dimension-1 register, opener-POS profile, punctuation rates) and gates drafts against the fingerprint as bands, not vibes.

日本語の概要は準備中です。原文の説明を表示しています。

Design evaluation datasets and supporting documentation for AI systems and agents, covering the scoping interview, difficulty distribution, dataset contract, sample review, and metric and tooling selection. Use when building or reviewing an evaluation set for a conversational agent, assistant, or retrieval-grounded AI system.

日本語の概要は準備中です。原文の説明を表示しています。

Run error analysis on a dataset. Build a review UI, select diverse samples, monitor annotations, and organize failure modes.

日本語の概要は準備中です。原文の説明を表示しています。