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概要と使いどころ
Confluence CQL search + space list + saved-filter + export via the confluence-as wrapper. Triggers: 'search confluence', 'find pages where X', 'cql for ...', 'export search results', 'list spaces', 'manage saved filters'. CQL injection-safe via the shared sanitizer. NOT for single-page CRUD (mk:confluence-page); NOT for bulk write ops (mk:confluence-bulk).
日本語の概要は準備中です。原文の説明を表示しています。
Controls error rates across thousands of simultaneous tests in genomics discovery using false-discovery-rate methods (Benjamini-Hochberg 1995; Benjamini-Yekutieli 2001 for arbitrary dependence; Storey q-value with pi0 estimation; local FDR; independent filtering Bourgon 2010; covariate-weighted FDR via IHW Ignatiadis 2016), plus family-wise error control (Bonferroni, Holm) and the GWAS genome-wide threshold. Covers the FDR-versus-FWER choice as the discovery-versus-confirmatory distinction, the dependence assumptions behind BH (PRDS) versus BY, pi0 estimation, the independent-filtering and false-coverage-rate traps, and reproducibility ranking via IDR (Li 2011). Use when correcting p-values from genome-wide tests, choosing between BH/BY/q-value/Bonferroni, setting an FDR threshold, applying IHW or independent filtering, or interpreting q-values. For confirmatory trials with few pre-specified endpoints (closed testing, graphical/gatekeeping), see clinical-biostatistics/multiplicity-graphical.
日本語の概要は準備中です。原文の説明を表示しています。
Aligns sample metadata with count matrices and constructs design matrices for downstream DE, handling the alphabetical-reference-level trap (relevel BEFORE DESeq), LRT reduced-model rules, the interaction-term resultsNames trap, continuous-covariate scaling and splines, repeated measures via duplicateCorrelation or dream, high-cardinality categorical pseudo-singular designs, sample swap detection via XIST/RPS4Y1 expression and somalier/NGSCheckMate genotypes, SABV (sex-as-biological-variable) mandate, Simpson's-paradox collapsing of technical replicates, and the `~ 0 + group` parameterization for clean contrasts. Use when building a design matrix, troubleshooting reversed fold-change direction, encoding paired or repeated-measures designs, detecting sample swaps, deciding sex-as-covariate, or aggregating technical replicates.
日本語の概要は準備中です。原文の説明を表示しています。
Performs differential expression on bulk RNA-seq count data with edgeR's negative-binomial GLM and quasi-likelihood F-test framework. Covers DGEList construction, filterByExpr, TMM/TMMwsp normalization, robust dispersion estimation, glmQLFit/glmQLFTest, TREAT for magnitude-bounded hypotheses, contrasts via no-intercept designs, voom and voomWithQualityWeights for heterogeneous samples, and the edgeR v4 bias-corrected APL changes. Use when running bulk DE with edgeR, choosing edgeR over DESeq2 (small n, transcript DE via catchSalmon, large samples), needing TREAT for a fold-change-threshold hypothesis, troubleshooting v3-to-v4 reproducibility, building paired or interaction designs, or handling library-quality heterogeneity.
日本語の概要は準備中です。原文の説明を表示しています。
Handles batch effects in bulk RNA-seq via design-matrix inclusion (the correct path for DE), ComBat/ComBat-seq for visualization, SVA for unknown latent factors, RUVSeq for negative-control-gene-anchored unwanted variation, and limma::removeBatchEffect for plotting only. Encodes the Nygaard 2016 cardinal sin against testing on a batch-corrected matrix, the choice between SVA/RUVg/RUVs/RUVr, the confounding non-identifiability problem, the single-cell boundary (Harmony/MNN are NOT for bulk), and the Goh 2017 harmonization critique. Use when designing a DE analysis with batch structure, troubleshooting batch-dominated PCA, choosing ComBat vs ComBat-seq, handling unknown batch via SVA, integrating across studies, or deciding when (rarely) to subtract batch.
日本語の概要は準備中です。原文の説明を表示しています。
Build Sankey, alluvial, river, and CONSORT-style flow diagrams to visualize cohort transitions, cell-state changes, or pipeline filtering using ggalluvial, networkD3, plotly, and consort. Use when showing how entities move between categories across timepoints (cell states, drug response classes, patient flow through a trial) or filtering pipelines (variants filtered through QC stages).
日本語の概要は準備中です。原文の説明を表示しています。
Infer orthologous genes and gene families across species using OrthoFinder3 (HOG-based phylogenetic orthology), SonicParanoid2, Broccoli, ProteinOrtho, OMA / FastOMA hierarchical orthologous groups, eggNOG-mapper, JustOrthologs, and TOGA whole-genome-alignment orthology. Use when building single-copy ortholog sets for phylogenomics, classifying co-orthologs and in/out-paralogs after gene duplication, propagating functional annotation via orthology with awareness of the ortholog conjecture, distinguishing speciation from duplication via gene-tree species-tree reconciliation, computing Quest-for-Orthologs benchmark performance, or running synteny-aware ortholog detection in WGD-affected lineages.
日本語の概要は準備中です。原文の説明を表示しています。
Detect horizontal gene transfer (HGT / LGT) using compositional methods (GC%, codon usage, tetranucleotide z-scores via SIGI-HMM, AlienHunter, IslandViewer 4, IslandPath-DIMOB), phylogenetic-incongruence methods (AvP, HGTphyloDetect, ALE / GeneRax / AleRax reconciliation, RANGER-DTL), and BLAST-distribution methods (HGTector v2, DarkHorse, Alien Index). Use when screening prokaryote genomes for genomic islands and HGT events, distinguishing HGT from incomplete lineage sorting / differential gene loss / hybridization, mapping donor lineages via phylogenetic placement, separating eukaryotic HGT from contamination, ruling out gBGC as a false signal, or quantifying DTL rates with ALE/GeneRax on bacterial trees.
日本語の概要は準備中です。原文の説明を表示しています。
Estimate causal effects of an exposure on an outcome from GWAS summary statistics using genetic instruments. Implements IVW (fixed/random), MR-Egger, weighted median/mode, MR-RAPS, CAUSE, GSMR-HEIDI, MR-PRESSO, MVMR, MR-Clust, LCV, and LHC-MR via TwoSampleMR, MendelianRandomization, MR-PRESSO, cause, and lhcMR. Use when testing causal direction between traits, evaluating drug-target effects via cis-pQTL/cis-eQTL, performing multivariable mediation MR, distinguishing causation from correlated horizontal pleiotropy, or producing STROBE-MR-compliant sensitivity batteries.
日本語の概要は準備中です。原文の説明を表示しています。
PM-mode brainstorm helper. Captures the requirement via Socratic dialogue before any entry phase (`/intake`, `/spec`, `/tdd`) drafts its artifact. Stage 0 skip-check, Stage 1 gap-analysis, Stage 2 probe-loop, Stage 3 confirm-and-persist. Output lives at `docs/brief/<slug>.md`. Never proposes solutions — Stage 2 dialogue discipline is structurally enforced via `discipline.mjs`.
日本語の概要は準備中です。原文の説明を表示しています。
Power batch-sprint helper — hosts the two behaviours that distinguish the `power` workflow track from spec-entry. (1) Per-ticket iteration: security runs once PER TICKET over workflow.json.tickets[] while the mechanical phases run once for the batch. (2) Commit split: at the commit phase, group the batch's working tree into ordered Conventional Commits via commit-split.mjs, closure last. Invoked within a `power`-track workflow; not a standalone feature. Opt-in via velocity.power_mode.enabled; requires git.
日本語の概要は準備中です。原文の説明を表示しています。
Use before non-trivial coding work to pick a task-appropriate working mode — debug, fix, review, test-first, refactor, optimize, migrate, upgrade, integrate, spike, or unstuck — then follow its checklist. Modes are procedures, not personas. Not needed for trivial one-line edits or non-coding tasks.
日本語の概要は準備中です。原文の説明を表示しています。
Interact with Langfuse and access its documentation. Use when needing to (1) query or modify Langfuse data programmatically via the CLI — traces, prompts, datasets, scores, sessions, and any other API resource, (2) look up Langfuse documentation, concepts, integration guides, or SDK usage, or (3) understand how any Langfuse feature works. This skill covers CLI-based API access (via npx) and multiple documentation retrieval methods.
日本語の概要は準備中です。原文の説明を表示しています。
Fetch aviation weather data (METAR, TAF, PIREPs)
日本語の概要は準備中です。原文の説明を表示しています。
This skill should be used when the user asks to "communicate via Discord", "send a message to Discord", "check Discord for instructions", "ask a question on Discord", "notify on Discord", "share a file on Discord", "離席する", "離席モード", "Discord で待機して", "Discord待機", or when Claude Code needs to reach the user who is away from the terminal.
Triage a single GitHub PR by PR number. Check out the PR's branch, detect conflicts with the target branch via `gh pr status` (and label the PR with `cc-resolve-conflict` if any are found), generate and evaluate a fix plan via create-review-fix-plan, then take action (add cc-fix-onetime label if fixes are needed, or merge the PR if it's ready).
日本語の概要は準備中です。原文の説明を表示しています。
Fetch any URL and convert to markdown using baoyu-fetch CLI (Chrome CDP with site-specific adapters). Built-in adapters for X/Twitter, YouTube transcripts, Hacker News threads, and generic pages via Defuddle. Handles login/CAPTCHA via interaction wait modes. Use when user wants to save a webpage as markdown.
日本語の概要は準備中です。原文の説明を表示しています。
Validate Commodore 1540/1541/1541C/1541-II compatible disk-drive behavior in EMULATORS, including IEC serial bus protocol, device numbers, KERNAL traps, CBM DOS commands/status, D64 image parsing, BAM/directory/file chains, PETSCII filenames, 6502 drive CPU/ROM/RAM expectations, 6522 VIA wiring, GCR/track/sector geometry, motor/head timing, and compatibility boundaries for 1541-like devices. Use when Codex reviews or edits C64, VIC-20, C264, COMMODORE disk, serial I/O, D64, CBM DOS, IEC, VIA, GCR, or 1541 drive code.
日本語の概要は準備中です。原文の説明を表示しています。
Goal-integrity skill. Use for backend/API/persistence, preserve/do-not-change, tests/validation, mocks, rework, multi-part requests. Emits Goal Contracts, Deviation Notices, Phase Checks, Final Audits. Skip for Q&A or trivial edits.
日本語の概要は準備中です。原文の説明を表示しています。
Monitors Certificate Transparency (CT) logs to detect unauthorized certificate issuance, discover subdomains via CT data, and alert on suspicious certificate activity for owned domains. Uses the crt.sh API and direct CT log querying based on RFC 6962 to build continuous monitoring pipelines that catch rogue certificates, track CA behavior, and map the external attack surface. Activates for requests involving certificate transparency monitoring, CT log auditing, subdomain discovery via certificates, or certificate issuance alerting.
日本語の概要は準備中です。原文の説明を表示しています。
Manage Things 3 via the `things` CLI on macOS (add/update projects+todos via URL scheme; read/search/list from the local Things database). Use when a user asks SolanaOS to add a task to Things, list inbox/today/upcoming, search tasks, or inspect projects/areas/tags.
日本語の概要は準備中です。原文の説明を表示しています。
Render CLIを使用したクラウドサービス管理の専門スキル。デプロイ、ログ監視、SSH接続、PostgreSQL接続、サービス管理などRenderプラットフォームのCLI操作を効率的に支援。定期的に公式ドキュメントをチェックして最新情報を取得。Use when managing Render services via CLI, deploying applications, viewing logs, connecting to databases, or automating cloud infrastructure tasks.
SF CLI経由でSalesforceレポートを作成するスキル。Metadata APIとREST APIの使い分け、フィールド命名規則、列数制限、レポートタイプ設定を網羅。カスタムオブジェクトレポート作成時の注意点も含む。Use when creating Salesforce reports via CLI, deploying report types, or automating report generation.
gogcli（gog コマンド）の専門家スキル。Google Workspace と関連サービス25以上（Gmail, Calendar, Chat, Drive, Sheets, Docs, Slides, Tasks, Keep, Contacts, People, Groups, Admin, Classroom, Forms, Meet, Maps, YouTube, Photos, Sites, Analytics, Search Console, Apps Script, Zoom）をターミナルから操作するGoベースCLIツールの使い方を支援。OAuth2/サービスアカウント認証、マルチアカウント管理、自動化・エージェント安全機能を提供。Use when working with Google Workspace services via CLI, managing Gmail/Calendar/Drive/Sheets, automating Google Workspace tasks, or setting up gogcli authentication.