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概要と使いどころ
Simplifies and refines code for clarity, consistency, and maintainability while preserving all functionality. Use when asked to "simplify code", "clean up code", "refactor for clarity", "improve readability", or review recently modified code for elegance. Focuses on project-specific best practices.
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How to author, edit, and adapt PostHog Signals scouts — the scheduled agents that scan a project and emit findings into the Signals inbox. Use when a user wants to customize a canonical scout for their own setup (narrow its scope, retune its thresholds, add disqualifiers), tweak a scout's schedule or dry-run posture, or write a brand-new scout from scratch for a specific use case (a custom event, a product surface no canonical scout covers). Covers the scout SKILL.md anatomy, the emit contract, the dedupe + scratchpad-memory conventions, the per-team skills-store path vs the canonical in-repo path, and the emit-and-inspect test loop (with dry-run as an optional safety net). Trigger on "write/edit/customize a signals scout", "new scout for X", "tune my scout schedule", "make a scout that watches <event>".
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Designs genomics experiments so technical nuisance variation (batch, lane, plate, flow cell, operator, reagent lot, processing day) is balanced against the biological variable of interest and therefore estimable rather than confounded, using constrained sample-to-batch assignment (designit, OSAT), the confounder/mediator/collider distinction, and the principle that no post-hoc correction recovers a fully confounded design. Covers detecting hidden batches with surrogate variable analysis, a decision table for downstream correction (ComBat-seq, RUVSeq, SVA) whose execution is deferred to differential-expression/batch-correction, and reproducibility metadata. Use when assigning samples to sequencing batches/lanes/plates, avoiding batch-condition confounding, deciding whether a design is salvageable by correction, choosing a correction method, or estimating the number of hidden batches. For the experimental unit, randomization, and blocking concepts see experimental-design/randomization-blocking.
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Performs subgroup and heterogeneous treatment effect (HTE) analyses for clinical trials. Covers Mantel-Haenszel pooling, Breslow-Day, interaction tests in regression, RERI for additive interaction, modern data-adaptive HTE methods (STEPP, SIDES, causal forests, X/R-learners), Bayesian shrinkage (Dixon-Simon, MAP, EXNEX), graphical multiplicity (Bretz-Maurer), and credibility frameworks (Sun BMJ, EMA 2019). Use when analyzing treatment effects across patient subgroups for regulatory submissions or precision-medicine claims.
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Post-training 4-bit quantization for LLMs with minimal accuracy loss. Use for deploying large models (70B, 405B) on consumer GPUs, when you need 4× memory reduction with <2% perplexity degradation, or for faster inference (3-4× speedup) vs FP16. Integrates with transformers and PEFT for QLoRA fine-tuning.
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Expert guidance for distributed training with DeepSpeed - ZeRO optimization stages, pipeline parallelism, FP16/BF16/FP8, 1-bit Adam, sparse attention
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Facebook's library for efficient similarity search and clustering of dense vectors. Supports billions of vectors, GPU acceleration, and various index types (Flat, IVF, HNSW). Use for fast k-NN search, large-scale vector retrieval, or when you need pure similarity search without metadata. Best for high-performance applications.
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Authors bioinformatics pipelines in WDL (Workflow Description Language) run by Cromwell or miniwdl, targeting the GATK/Broad and Terra/AnVIL/BioData Catalyst cloud ecosystem, with tasks, workflows, scatter-gather parallelism, structs, and a runtime block that sizes the cloud VM. Use when deciding to target Terra/AnVIL/GATK/WARP (chosen for the ecosystem, not the language); sizing runtime disks dynamically for a fresh-per-task cloud VM (ceil(size(f)*factor)+buffer); choosing preemptible vs on-demand VMs by task length and idempotency; picking Cromwell (production, cloud, call-caching) vs miniwdl (local dev, miniwdl check linting, readable errors); enabling and debugging call-caching silent-miss modes; pinning Docker by digest for reproducibility and cache stability; or scattering an array for parallel fan-out.
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Orchestrates an end-to-end MeRIP-seq / m6A-seq analysis from raw FASTQ to differential m6A peak calls and metagene plots, chaining fastp adapter trimming, STAR splice-aware alignment (NO deduplication for non-UMI MeRIP), deepTools replicate-concordance + IP-enrichment QC, PreSeq saturation curves, exomePeak2 (transcript-aware Poisson GLM) peak calling, optional MACS3 broad-peak cross-check, DRACH motif confirmation as a sanity check (NOT a per-peak filter), exomePeak2 differential calling via the four-BAM-vector interface (bam_ip + bam_input control; bam_treated_ip + bam_treated_input treatment), ChIPseeker annotation, and the canonical Guitar metagene with stop-codon enrichment as the biological QC anchor. Use when running a complete MeRIP analysis from raw reads, when chaining the constituent epitranscriptomics skills (merip-preprocessing -> m6a-peak-calling -> m6a-differential -> modification-visualization), or when wrapping the pipeline in Snakemake / Nextflow.
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End-to-end clinical trial analysis workflow from CDISC SDTM/ADaM loading through ICH E9(R1) estimand-driven primary analysis to CONSORT 2025 regulatory-compliant reporting. Covers data preparation, FDA 2023 marginal vs conditional logistic regression, categorical tests with Boschloo, modern HTE/subgroup methods, missing-data sensitivity (MMRM, reference-based MI, Permutt tipping point), graphical multiplicity (Bretz-Maurer), survival analysis (Cox/RMST/competing risks) when applicable, and Table 1. Use when performing a complete analysis of clinical trial data.
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Literature: retrieve document-level scientific evidence from publications, clinical-trial registries, and patent sources. Use for PubMed records, reproducible searches, trial registrations, patent evidence, abstracts, study metadata, stable identifiers, and citation provenance.
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Preserve user work, scope, metadata, history, and verifiable delivery.
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Port one complete feature family with provenance, current-API adaptation, repository ownership, localization, resources, and verification.
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Build AI tutoring systems with adaptive learning. TRIGGERS - Use when user needs help with ai-education-tutor related tasks.
日本語の概要は準備中です。原文の説明を表示しています。
Create ADA accessibility compliance checklists. TRIGGERS - Use when user needs help with accessibility-compliance related tasks.
日本語の概要は準備中です。原文の説明を表示しています。
Extract headline, author, publication date, summary, category, and named entities from a public news article.
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Extract clean title, summary, markdown sections, and source metadata from a public documentation page for RAG ingestion.
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Extract title, authors, abstract, and citation info from academic papers.
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Listens to a CARLA sensor and either saves its data to files, shows it live in a window, prints a one-shot summary, or (ros-info) reports the native ROS 2 topics, QoS and enabled-for-ROS state so you can echo it from ROS instead. Cameras save as PNG (depth/semantic auto-colourised) and display in a pygame window; lidar saves as .ply and shows as a top-down scatter; IMU/GNSS/radar/collision stream to JSONL or the console. Use when the user asks to "show/view the camera", "display the lidar", "save the sensor data / capture a dataset", or "what is this sensor reading". Select the sensor by id, type, or the actor it's attached to.
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Spawns and attaches sensors on a running CARLA server — cameras (rgb/depth/semantic/instance/optical-flow/normals), lidar, radar, IMU, GNSS, collision/lane-invasion/obstacle — to the ego or any actor, with a mount transform and blueprint attributes (resolution, fov, sensor_tick, lidar range/points, …). Also sets up native ROS 2 publishing (--ros to enable_for_ros, --ros-name/--ros-frame-id topic and TF naming) and prints the topics the sensor will publish. Use when the user asks to "add a camera/lidar/sensor", "put a dashcam on the ego", "attach a depth camera", "mount a sensor", or "publish a sensor to ROS". Prints the sensor id; read its data with the read-sensor skill.
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Reads and summarises ScenarioRunner output — the criteria pass/fail tables from --output/--file, the machine-readable --json and --junit result files, and the criteria JSON written alongside a --record recording — and runs the metrics module (metrics_manager.py) to compute custom measurements over a recorded run offline, without the simulator. Use when the user asks "did the scenario pass", "why did it fail", "summarise these results", "compare these runs", or wants distance/speed/lane metrics from a recording.
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Use when writing or auditing the conversational copy layer of a Salesforce bot or Agentforce agent: utterance authoring strategy, fallback message copy, escalation-criteria phrasing, and persona-consistent dialog scripting across channels. NOT for platform configuration (bot builder setup, topic metadata wiring, action mapping, or Agentforce deployment) — see architect/einstein-bot-architecture and agentforce/agentforce-persona-design for those concerns.
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Run agent-adapted STRIDE + access-control analysis on an agent system. Produces a ranked risk list with agentic mitigations (scope / split / filter / gate / review).
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Three-file state management for session continuity. Maintains STATE.md, DECISIONS.md, and PROGRESS.md as human-readable session context alongside the SQLite ticket database. Use this skill when updating workflow state, logging decisions, tracking session progress, or resuming work after a context break.
日本語の概要は準備中です。原文の説明を表示しています。