「ols」の検索結果

Designs adaptive clinical trials including group-sequential (O'Brien-Fleming, Pocock, Lan-DeMets spending), sample-size re-estimation (blinded Friede-Kieser, unblinded Cui-Hung-Wang, Mehta-Pocock promising zone), seamless Phase 2/3 with treatment-arm selection, population enrichment, and response-adaptive randomisation. Covers FDA 2019 Final Adaptive Designs Guidance, FDA 2022 Master Protocols, and ICH E20 Step 2b/3 draft (June 2025, NOT final). Use when planning interim analyses, sample-size re-estimation, or master/platform-trial designs.

日本語の概要は準備中です。原文の説明を表示しています。

End-to-end protein design pipeline guide across preparation, generation, validation, and filtering. Use this skill when: (1) Starting a new protein design project, (2) Need step-by-step workflow guidance, (3) Understanding the full design pipeline, (4) Planning compute resources and timelines, (5) Integrating multiple design tools. For tool selection, use binder-design-tool-selection. For QC thresholds, use protein-design-qc.

日本語の概要は準備中です。原文の説明を表示しています。

Binder design tool selection and workflow routing guidance. Use this skill when: (1) Deciding between BoltzGen, BindCraft, or RFdiffusion, (2) Planning a binder design campaign, (3) Understanding trade-offs between different approaches, (4) Selecting tools for specific target types. For specific tool parameters, use the individual tool skills (boltzgen, bindcraft, rfdiffusion, etc.).

日本語の概要は準備中です。原文の説明を表示しています。

Guidance for choosing the right protein binder design tool. Use this skill when: (1) Deciding between BoltzGen, BindCraft, or RFdiffusion, (2) Planning a binder design campaign, (3) Understanding trade-offs between different approaches, (4) Selecting tools for specific target types. For specific tool parameters, use the individual tool skills (boltzgen, bindcraft, rfdiffusion, etc.).

日本語の概要は準備中です。原文の説明を表示しています。

End-to-end guidance for protein design pipelines. Use this skill when: (1) Starting a new protein design project, (2) Need step-by-step workflow guidance, (3) Understanding the full design pipeline, (4) Planning compute resources and timelines, (5) Integrating multiple design tools. For tool selection, use binder-design. For QC thresholds, use protein-qc.

日本語の概要は準備中です。原文の説明を表示しています。

End-to-end binder design using BindCraft hallucination. Use this skill when: (1) Designing protein binders with built-in AF2 validation, (2) Running production-quality binder campaigns, (3) Using different design protocols (fast, default, slow), (4) Need joint backbone and sequence optimization, (5) Want high experimental success rate. For backbone-only generation, use rfdiffusion. For QC thresholds, use protein-qc. For tool selection guidance, use binder-design.

日本語の概要は準備中です。原文の説明を表示しています。

Portable multi-source research with cross-source validation and an offline evidence ledger. Use for fact-checking, comprehensive research, or any question requiring multiple independent perspectives; work with the host agent's search tools and optionally add SandBase Tavily, Exa, Scholar, and Cloudsway coverage.

日本語の概要は準備中です。原文の説明を表示しています。

Identify the technology stack powering any website — frameworks, CMS, analytics, hosting, CDN, payment processors, and marketing tools. Useful for competitive intelligence, sales prospecting, and technology landscape research.

日本語の概要は準備中です。原文の説明を表示しています。

Plan, implement, or review vs code extension localization work in an existing codebase with compatibility, security, and verification controls. Use when the user explicitly requests vs code extension localization work.

日本語の概要は準備中です。原文の説明を表示しています。

Plan, implement, or review verification before completion work in an existing codebase with compatibility, security, and verification controls. Use when the user explicitly requests verification before completion work.

日本語の概要は準備中です。原文の説明を表示しています。

Plan, implement, or review writing plans work in an existing codebase with compatibility, security, and verification controls. Use when the user explicitly requests writing plans work.

日本語の概要は準備中です。原文の説明を表示しています。

Discover and evaluate KOLs (Key Opinion Leaders) and creators across TikTok, Instagram, YouTube, and Xiaohongshu through SandBase. Use when asked for influencer research, creator outreach lists, KOL evaluation, or partnership prospecting.

日本語の概要は準備中です。原文の説明を表示しています。

Create, implement, or review video template frame light leak cinema work with format, accessibility, performance, and visual-verification controls. Use when the requested deliverable depends on video template frame light leak cinema.

日本語の概要は準備中です。原文の説明を表示しています。

Plan, implement, or review vector index tuning work in an existing codebase with compatibility, security, and verification controls. Use when the user explicitly requests vector index tuning work.

日本語の概要は準備中です。原文の説明を表示しています。

Create, implement, or review video template frame glitch title work with format, accessibility, performance, and visual-verification controls. Use when the requested deliverable depends on video template frame glitch title.

日本語の概要は準備中です。原文の説明を表示しています。

Create, implement, or review tailwind design system work with format, accessibility, performance, and visual-verification controls. Use when the requested deliverable depends on tailwind design system.

日本語の概要は準備中です。原文の説明を表示しています。

Create or review revenue operations deliverables with traceable assumptions, decision criteria, ownership, and risk controls. Use when the user asks for revenue operations planning or analysis.

日本語の概要は準備中です。原文の説明を表示しています。

Create or review team composition analysis deliverables with traceable assumptions, decision criteria, ownership, and risk controls. Use when the user asks for team composition analysis planning or analysis.

日本語の概要は準備中です。原文の説明を表示しています。

Plan, implement, or review observability and instrumentation work in an existing codebase with compatibility, security, and verification controls. Use when the user explicitly requests observability and instrumentation work.

日本語の概要は準備中です。原文の説明を表示しています。

Plan, implement, or review prometheus configuration work in an existing codebase with compatibility, security, and verification controls. Use when the user explicitly requests prometheus configuration work.

日本語の概要は準備中です。原文の説明を表示しています。

Create, implement, or review penpot ui/ux design work with format, accessibility, performance, and visual-verification controls. Use when the requested deliverable depends on penpot ui/ux design.

日本語の概要は準備中です。原文の説明を表示しています。

Create, implement, or review oversized cursor work with format, accessibility, performance, and visual-verification controls. Use when the requested deliverable depends on oversized cursor.

日本語の概要は準備中です。原文の説明を表示しています。

Plan, implement, or review similarity search patterns work in an existing codebase with compatibility, security, and verification controls. Use when the user explicitly requests similarity search patterns work.

日本語の概要は準備中です。原文の説明を表示しています。

Plan, implement, or review refactor work in an existing codebase with compatibility, security, and verification controls. Use when the user explicitly requests refactor work.

日本語の概要は準備中です。原文の説明を表示しています。