「clinical」の検索結果

treekoR is a novel framework that aims to utilise the hierarchical nature of single cell cytometry data to find robust and interpretable associations between cell subsets and patient clinical end points. These associations are aimed to recapitulate the nested proportions prevalent in workflows inovlving manual gating, which are often overlooked in workflows using automatic clustering to identify cell populations. We developed treekoR to: Derive a hierarchical tree structure of cell clusters; qua

日本語の概要は準備中です。原文の説明を表示しています。

Find the papers that answer a research query in Firecrawl's research paper index — a corpus of paper abstracts whose largest share is biomedical and life-science literature (PubMed, bioRxiv, medRxiv), alongside arXiv preprints in CS, physics, and math — using semantic search, semantic and structural expansion, and in-body verification. Use this skill for literature-finding and paper-retrieval tasks of any kind, including clinical, biomedical, drug, gene, disease, and other life-science questions, whether the answer is a single paper or a full multi-paper set. The index is reached only through the `firecrawl_research_*` MCP tools or the `firecrawl research` CLI subcommands. Calling `firecrawl_search` with its `categories` option set to `["research"]` is a different feature — it filters ordinary web search to research-affiliated websites (the list includes PubMed, bioRxiv, medRxiv, arXiv, and publisher sites) and returns page results from them, without querying the paper records in this index.

日本語の概要は準備中です。原文の説明を表示しています。

Your healthcare and life sciences brain trust. 25 named personas across 7 cells covering drug discovery, medtech, biotech strategy, health policy, genomics, clinical trials, and healthcare economics.

日本語の概要は準備中です。原文の説明を表示しています。

Assign CPT and HCPCS Level II procedure codes from clinical documentation the way a professional coder builds the claim. Use when users say "code this encounter for procedures", "what CPT codes apply", "assign HCPCS codes", "code this op note", or when turning visit notes or operative reports into claim-ready procedure codes.

日本語の概要は準備中です。原文の説明を表示しています。

Automate payer review of prior authorization (PA) requests. This skill should be used when users say "Review this PA request", "Process prior authorization for [procedure]", "Assess medical necessity", "Generate PA decision", or when processing clinical documentation for coverage policy validation and authorization decisions.

日本語の概要は準備中です。原文の説明を表示しています。

Connect to a hospital's FHIR R4 server (Epic, Oracle Health/Cerner, MEDITECH, athenahealth, or any SMART-on-FHIR endpoint), pull a patient's clinical data and notes, and extract structured findings. Use when users say "connect to the EHR", "connect to Epic/Cerner", "pull notes for patient X", "what do the last 6 months of notes say about Y", or any task that starts from a live EHR rather than pasted text.

日本語の概要は準備中です。原文の説明を表示しています。

Query NCBI ClinVar for variant clinical significance. Search by gene/position, interpret pathogenicity classifications, access via E-utilities API or FTP, annotate VCFs, for genomic medicine.

日本語の概要は準備中です。原文の説明を表示しています。

Autonomous biomedical AI agent framework for executing complex research tasks across genomics, drug discovery, molecular biology, and clinical analysis. Use this skill when conducting multi-step biomedical research including CRISPR screening design, single-cell RNA-seq analysis, ADMET prediction, GWAS interpretation, rare disease diagnosis, or lab protocol optimization. Leverages LLM reasoning with code execution and integrated biomedical databases.

日本語の概要は準備中です。原文の説明を表示しています。

Query NCBI ClinVar via E-utilities for variant clinical significance, pathogenicity, disease associations. Search by gene/rsID/condition/review status; returns ClinSig, submitter data, conditions, HGVS. For GWAS use gwas-database; for variant consequence prediction use Ensembl VEP.

日本語の概要は準備中です。原文の説明を表示しています。

gnomAD v4 population variant frequencies via GraphQL API. Allele counts and frequencies stratified by ancestry (AFR, AMR, EAS, NFE, SAS, FIN, ASJ, MID), gene-level constraint (pLI, LOEUF, missense z), and coverage. Identify rare or constrained variants. For clinical pathogenicity use clinvar-database; for GWAS use gwas-database.

日本語の概要は準備中です。原文の説明を表示しています。

Monarch Initiative knowledge graph REST API for disease-gene-phenotype associations and cross-species orthology. MONDO disease-to-gene/phenotype, HP phenotype profiles, cross-species comparisons. Use for rare disease gene prioritization and phenotype-based candidate ranking. For GWAS use gwas-database; for clinical pathogenicity use clinvar-database.

日本語の概要は準備中です。原文の説明を表示しています。

Query the ClinPGx (formerly PharmGKB) REST API plus the CPIC PostgREST companion API for pharmacogenomic clinical annotations, CPIC/DPWG dosing guidelines, gene-drug pairs, variant-drug associations, FDA/EMA drug labels, and PGx pathways. Two-host architecture: api.clinpgx.org for annotation records, api.cpicpgx.org for genotype→recommendation lookups. No auth. For germline pathogenicity use clinvar-database; for somatic cancer PGx use cosmic-database or opentargets-database; for drug bioactivity use chembl-database-bioactivity.

日本語の概要は準備中です。原文の説明を表示しています。

Cancer genomics (TCGA et al.) via cBioPortal REST API. Retrieve somatic mutations, CNAs, expression, clinical data (survival/stage/treatment) across thousands of studies. Use for TMB, oncoprints, survival analysis. For population frequencies use gnomad-database; for drug-gene interactions use opentargets-database.

日本語の概要は準備中です。原文の説明を表示しています。

Query openFDA REST API for adverse events (FAERS), labeling, product info, recalls, enforcement. Search by drug name, ingredient, MedDRA, or NDC. 1k req/day no key; 120k with free key. For trials use clinicaltrials-database-search; for structures use drugbank-database-access or chembl-database-bioactivity.

日本語の概要は準備中です。原文の説明を表示しています。

Evaluating scientific evidence and claims. Covers study design hierarchy (RCT to expert opinion), effect sizes (OR, RR, NNT, Cohen's d), confounding, p-value vs clinical significance, GRADE quality assessment, reproducibility, and bias types (selection, information, confounding, reporting). Use when reading a paper or assessing claims.

日本語の概要は準備中です。原文の説明を表示しています。

Systematic strategies for searching scientific literature across PubMed, arXiv, Google Scholar, and AI-assisted tools. Covers PICO framework for clinical questions, three-tiered search (database-specific, AI-assisted, content extraction), PubMed field tags and MeSH, boolean query construction, and full-text extraction. Use when planning a literature search or choosing a search tier.

日本語の概要は準備中です。原文の説明を表示しています。

Query Open Targets GraphQL API for target-disease associations, evidence, drug links, safety. Search targets by gene, diseases by EFO ID; scores from 20+ sources, drug mechanisms, tractability. For ChEMBL use chembl-database-bioactivity; for trials use clinicaltrials-database-search.

日本語の概要は準備中です。原文の説明を表示しています。

Query DDInter drug-drug interactions via REST API (1.7M+ interactions, 2,400+ drugs). Search by drug name/ID for severity (major/moderate/minor), mechanisms, and clinical recommendations. No auth. For FDA labeling use dailymed-database; for pharmacogenomics use clinpgx-database.

日本語の概要は準備中です。原文の説明を表示しています。

protocols.io REST API: search and fetch wet-lab, bioinformatics, and clinical protocols by keyword, DOI, or category, with steps, reagents, materials, equipment, timing. Public access free; auth needed for private or publishing. Pair with opentrons-protocol-api or benchling-integration to execute.

日本語の概要は準備中です。原文の説明を表示しています。

Use when looking for a meta-analysis topic before any protocol exists. Starts from a professor's publication profile or from a clinical question, finds gaps, assesses feasibility and returns a ranked topic list. Running the review itself is /meta-analysis.

日本語の概要は準備中です。原文の説明を表示しています。

Use when a clinical CSV/Excel dataset needs profiling and cleaning before analysis (missing values, outliers, duplicates, type mismatches). Profiles, flags and generates cleaning code in three stages, each gated on the researcher's approval. Never auto-cleans.

日本語の概要は準備中です。原文の説明を表示しています。

Use when clinical data may contain PHI and must be de-identified before any LLM-assisted analysis. A local Python script (no network or AI calls) detects identifiers with regex and heuristics in 11 country locale packs, with interactive terminal review.

日本語の概要は準備中です。原文の説明を表示しています。

Use when building or auditing a radiomics or tabular clinical-ML prediction model with a classical learner (LASSO, SVM, random forest, XGBoost and similar). Enforces nested CV, dimensionality control, in-fold feature selection, feature stability, calibration and external validation.

日本語の概要は準備中です。原文の説明を表示しています。

Apply the bioengineering, mechanobiology, and lymphatic transport reasoning of J. Brandon Dixon, professor of mechanical and biomedical engineering at Georgia Institute of Technology. Reach for this skill whenever analyzing lymphatic biomechanics, active vessel contractility versus passive drainage, peristaltic fluid transport, microfluidic organ-on-a-chip design, preclinical lymphedema models, non-invasive functional imaging, targeted nanomedicine delivery, or automated disease staging. Use this skill to critique bioengineering assumptions, guide quantitative protocol design, evaluate biomechanical pump failure, and formulate interdisciplinary biomedical solutions.

日本語の概要は準備中です。原文の説明を表示しています。