「confidence」の検索結果

Abductive reasoning about causes. Takes a phenomenon, separates observations from interpretations, then spawns diagnosticians applying different reasoning lenses (technical, human-factors, process, incentive-structure, environmental, temporal, measurement-artifact, statistical) in isolation. Orchestrator evaluates candidate causes for fit-against-evidence, calibrates confidence honestly, and reports leading candidate(s) with distinguishing evidence needed. Produces feedback only — no code, no tickets, no artifacts.

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Use when running a hosted Crewrift policy A/B and judging it with Wilson confidence intervals.

日本語の概要は準備中です。原文の説明を表示しています。

Instinct-based learning system that observes sessions via hooks, creates atomic instincts with confidence scoring, and evolves them into skills/commands/agents. v2.1 adds project-scoped instincts to prevent cross-project contamination.

日本語の概要は準備中です。原文の説明を表示しています。

Applies safe auto-fixes for low-risk audit findings (unused imports, dead code, commented-out code). Confidence >=90% only. Creates single commit with summary.

日本語の概要は準備中です。原文の説明を表示しています。

Structured multi-criteria decision analysis for ranking options with weights, constraints, confidence, tradeoff reasoning, sensitivity analysis, and explainable recommendations. Use when the user asks for decision support, MCDA, weighted scoring, prioritization, vendor selection, route planning, hiring shortlist ranking, tool comparison, procurement decisions, or auditable agent decision logic.

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Select, write, or review proportionate tests and verification for dygo Go packages, PostgreSQL behavior, metadata, CLI contracts, Studio, integrations, and releases. Use when test scope or confidence strategy is the main decision.

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Chief Security Officer mode. Infrastructure-first security audit: secrets archaeology, dependency supply chain, CI/CD pipeline security, LLM/AI security, skill supply chain scanning, plus OWASP Top 10, STRIDE threat modeling, and active verification. Two modes: daily (zero-noise, 8/10 confidence gate) and comprehensive (monthly deep scan, 2/10 bar). Trend tracking across audit runs. Use when: "security audit", "threat model", "pentest review", "OWASP", "CSO review".

日本語の概要は準備中です。原文の説明を表示しています。

Research-validated planning — research → plan → verify cycle for high-confidence implementation plans

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Pragmatic testing guidance focused on confidence, behavior over implementation details, and integration-first coverage. Use when designing a test strategy, writing or reviewing tests, reducing brittle mocks, or deciding what is worth testing in an application or library.

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Benchmark multi-agent coordination systems with experiment design, power analysis, human rating protocols, bootstrap confidence intervals, and reproducible reporting. Use for salvage latency, recovery fidelity, coordination overhead, and protocol comparison studies. NOT for ML model benchmarking, web-product A/B testing, survey design, or general-purpose data science.

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Synthesizes actionable feedback from validation results, confidence scores, and iteration triggers. Creates structured improvement guidance for re-execution. Activate on 'synthesize feedback', 'improvement suggestions', 'actionable feedback', 'iteration guidance', 'feedback generation'. NOT for iteration detection (use dag-iteration-detector) or convergence tracking (use dag-convergence-monitor).

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Call germline SNPs and indels with GATK HaplotypeCaller and the GVCF joint-genotyping workflow. Covers the local-reassembly + PairHMM mechanism (why HC beats pileup callers on indels), the -ERC GVCF reference-confidence model and <NON_REF> allele, BQSR-vs-DRAGSTR and --dragen-mode error modeling, allele-specific (AS_) annotations, and edge cases (ploidy, Mutect2 mitochondria mode, sex chromosomes/PAR, contamination gating). Use when deciding whether to use HaplotypeCaller vs a pileup or DRAGEN caller, whether BQSR still earns its place, whether to call per-sample GVCFs for a cohort, or how to handle non-diploid, mitochondrial, sex-chromosome, or contaminated samples. Not for post-calling filtering depth (see variant-calling/filtering-best-practices) or cohort joint-genotyping scaling (see variant-calling/joint-calling).

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Quality control for pooled CRISPR screens covering library representation, Gini index, log-skew, replicate Pearson and Spearman concordance, essentialome precision-recall AUC against CEGv2 (Hart 2017), Cas9 cut-toxicity diagnostics, copy-number amplicon detection (Aguirre 2016 / Munoz 2016), bottleneck propagation through plasmid pool, infection, selection, and endpoint stages, MOI verification, and DepMap-style screen-quality scoring. Use when assessing screen quality before hit calling, deciding whether to repeat or rescue a screen, diagnosing low-confidence hits, choosing between MAGeCK / BAGEL2 / Chronos based on quality grade, picking a normalization strategy from QC signatures, or evaluating whether an in-vivo screen retained adequate library complexity.

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Cross-method decision tree for calling hits in pooled CRISPR screens. Catalogs statistical models (MAGeCK RRA, MAGeCK MLE, BAGEL2, drugZ, JACKS, Chronos, CERES), experimental designs each is built for, failure modes outside design domain, reconciliation when methods disagree, multiple-testing and effect-size thresholds, the order of operations (count -> QC -> CN-correct -> hit-call -> validate), the second-best-sgRNA conservative rule, and consensus-hit strategy. Use when choosing among MAGeCK / BAGEL2 / drugZ / JACKS / Chronos for a given design, reconciling disagreement across two or three methods on the same screen, deciding whether to require consensus, gating downstream validation by hit-confidence tier, or interpreting unstable hit lists across reruns.

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Computes and interprets treatment effect measures (OR, RR, RD, HR, NNT) with calibrated confidence intervals (Wilson, Newcombe, Miettinen-Nurminen, MOVER, profile likelihood, Bender NNT) and reports marginal vs conditional estimands per FDA 2023 covariate adjustment guidance. Use when reporting treatment effects in confirmatory trials, comparing effect sizes across studies, or constructing forest plots.

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Tests associations between categorical variables in clinical data using chi-square, Fisher's exact, Boschloo, Cochran-Mantel-Haenszel, and modern McNemar variants with calibrated confidence intervals (Wilson, Newcombe, Miettinen-Nurminen). Use when analyzing categorical outcomes, paired binary endpoints, or testing treatment-outcome independence in confirmatory or exploratory clinical trials.

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Validate protein designs using AlphaFold2 structure prediction. Use this skill when: (1) Validating designed sequences fold correctly, (2) Predicting binder-target complex structures, (3) Calculating confidence metrics (pLDDT, pTM, ipTM), (4) Self-consistency validation of designs, (5) Multi-chain complex prediction with AlphaFold-Multimer. For faster single-chain prediction, use esm. For QC thresholds, use protein-qc.

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Access AlphaFold's 200M+ AI-predicted protein structures. Retrieve structures by UniProt ID, download PDB/mmCIF files, analyze confidence metrics (pLDDT, PAE), for drug discovery and structural biology.

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Verify every claim from multiple independent angles -- code, docs, tests, git history. Use when you need high confidence that something is correct before acting on it.

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Pressure-test an existing plan or design artifact until it is coherent enough for the next workflow step or plainly blocked. Use when the user wants to be grilled on a plan, design doc, PRD, ADR, rollout plan, migration runbook, rolling-wave project shape, or slice contract; when they say "grill me"; or when Codex should interrogate a source-of-truth artifact, inspect code and adjacent docs before asking, auto-answer evidence-backed questions, ask only about conflicts or low-confidence recommendations, edit the original file in place, preserve the artifact's existing format, and keep conclusions, blockers, readiness, and deferred work synchronized in the document.

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Review local git changes before opening a PR or merging. First review all local tracked and untracked files; if none exist, review the current branch against a requested base branch or the Git Town parent branch. Use zero to three review subagents only when risk, diff size, language specificity, or uncertainty justifies the token cost, then report high-confidence bugs, regressions, risky assumptions, and missing tests. Use when the user asks for code review, local review, branch sanity check, pre-PR review, or review of work-in-progress changes.

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Expert-level statistics knowledge. Use when working with probability distributions, hypothesis testing, regression, Bayesian statistics, statistical inference, experimental design, ANOVA, or statistical modeling. Also use when the user mentions 'p-value', 'confidence interval', 'hypothesis test', 'regression', 'ANOVA', 'chi-square', 't-test', 'Bayesian', 'maximum likelihood', 'statistical significance', 'correlation', 'normal distribution', or 'sampling distribution'.

日本語の概要は準備中です。原文の説明を表示しています。

Run an infrastructure-first security audit of a repository - secrets archaeology, dependency supply chain, CI/CD pipeline, LLM/AI attack surface, agent skill supply chain, OWASP Top 10, STRIDE threat model, and data classification - with a confidence gate and a pre-emit verification gate that suppress speculative findings. Use when asked for a security audit, threat model, pentest-style review, OWASP pass, or a pre-release security check. Not for reviewing a single diff - use review-changes or requesting-code-review for that.

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Interactive agent-flow setup. Scans the repo read-only, proposes AGENTS.md, DOCS_INDEX.md and CONTEXT_MANIFEST.json with a confidence marker per claim, asks the user for protected paths and risk boundaries, writes each file only after approval. Use when setting up agent-flow, when context files are missing, or when asked to write an AGENTS.md, onboard a repo for AI agents or set protected paths.

日本語の概要は準備中です。原文の説明を表示しています。