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概要と使いどころ
Use when the user explicitly asks for a desktop or system screenshot (full screen, specific app or window, or a pixel region), or when tool-specific capture capabilities are unavailable and an OS-level capture is needed.
日本語の概要は準備中です。原文の説明を表示しています。
Inspects PostHog Visual Review (VR) runs that gate PR merges with screenshot regression checks. Use when the user mentions "visual review", "VR", "snapshot diff", "screenshot test", "storybook regression", "playwright snapshot", asks why a PR is blocked or what changed visually, wants to triage the VR backlog, decide whether a snapshot diff is real vs flaky, or check whether a story has been changing across runs. Also invoke when a PR has a failing `visual-review` status check, when a PR comment mentions "Visual review", or when the user is on a branch with an open VR run.
日本語の概要は準備中です。原文の説明を表示しています。
Generate a visual changelog or PR description by taking before/after screenshots of UI changes using Cursor's built-in browser. Use when preparing a PR with visual changes.
日本語の概要は準備中です。原文の説明を表示しています。
pen.dev CLI（`pencil` / `pen`コマンド）だけを使って.penファイル（pen.devで作成されたデザインファイル）をAIプロンプトまたは決定論的な編集操作で修正・更新・新規作成するスキル。.penファイルの編集、ボタン追加、レイアウト変更、UIデザインの調整、pen.devデザインの更新、新しい.penデザインの作成などの依頼で必ず使用する。AI任せの編集・新規作成はエージェントモード（`pencil --in --out --prompt`）で行い、既存ファイルは同一パスを指定して上書き、新規作成は`--in`を省略して`--out`に新しいパスを指定する。決定論的な編集はインタラクティブモード（`pencil interactive`）の`execute`（`Insert` / `Update` / `Delete` など）で行い、最後に`save()`する。編集・作成後は「**編集・作成したコンポーネントのNodeだけ**」を`execute`の`Export` / `TakeScreenshot`でPNG出力し、`.pen`と同階層の`snapshots/`ディレクトリに保存する。pen.dev MCPには依存せず`pencil`コマンドのみで完結する。.penファイルのgitコンフリクト解消・破損復旧は本スキルではなく`resolve-pencil-conflict`スキルの担当。
pen.dev CLI（`pencil` / `pen`コマンド）だけを使って、.penファイル（pen.devで作成されたデザインファイル）の中のNodeのデザインデータ（属性・構造）とスクリーンショット画像を読み取り専用で取得するスキル。Node ID指定に加え、名前の正規表現（例: 「ヘッダー」「.*Button」）、Nodeタイプ（frame / text / image など）、再利用可能コンポーネント、特定Node配下、ドキュメント全体のトップレベルなど、**ID以外の指定方法**にも対応する。ユーザーが「.penのこのNodeの中身を見せて」「特定コンポーネントのデザインデータを取り出して」「Nodeのスクリーンショットだけ欲しい」「ヘッダーの構造を確認したい」「ボタンのスタイルをコピーしたい」「再利用可能コンポーネント一覧を見せて」「ドキュメント全体の構造を覗きたい」「全てのテキストNodeを取得して」のように.pen内の要素の調査・参照・確認・抜き出しを依頼した場合に必ずこのスキルを使う。インタラクティブモード（`pencil interactive`）で `execute` の `Get` / `Print`（読み取り専用関数のみ）を使ってNode属性を取得し、同じ `execute` の `Export` / `TakeScreenshot` で画像を`.pen`と同階層の`snapshots/`にPNG出力する。編集はしない（`save()` も変更系関数も呼ばない）ため、対象ファイルは絶対に書き換わらない。pen.dev MCPには依存せず`pencil`コマンドのみで完結。
The default code-driven browser path for interactive browsing work: drives any browser from code with token-efficient a11y snapshots (57% smaller via compactSnapshot), ref-based clicks, coordinate control (CUA), viewport pinning, CAPTCHA solving (reCAPTCHA, Turnstile, hCaptcha, slider, OCR), Chrome MV3 APIs (tabs/bookmarks/history/downloads/topSites), network snoop (read API JSON instead of DOM), flight-recorder trace (jsonl + HAR + screenshots), OOPIF-aware snapshots, dialog policy, human handoff for login/OTP, device emulation, request routes, stealth via CloakBrowser as the default owned engine with zero exposed CDP ports, and an attached engine that drives the user's own signed-in browser through BrowserSkill (connectBrowserSkill, bskSnapshot, one-click onboarding via bskOnboard). MUST USE for interactive browser work: scraping, blocked/WAF/JS-rendered pages, logins, the user's logged-in sites and open tabs, extension popups, form filling, screenshots, web QA, CAPTCHAs. The ulw-research browsing lane runs on ultimate-browsing, not this skill.
日本語の概要は準備中です。原文の説明を表示しています。
Corrects the gene-independent copy-number artifact in CRISPR-Cas9 screens (Aguirre 2016 / Munoz 2016 Cancer Discov) where amplified loci appear essential from DNA-damage burden of simultaneous cuts. Covers the p53-dependent G2-arrest mechanism, CRISPRcleanR (Iorio 2018) unsupervised pre-hoc correction, CERES (Meyers 2017) joint CN + gene-effect model, Chronos (Dempster 2021) DepMap-standard population-dynamics + CN model with lowest residual bias, the decision tree by data availability, the Spearman LFC-vs-CN diagnostic, focal-amplification examples (ERBB2 in HER2+, MYC in colorectal, FGFR1 in head and neck), and CRISPRi/a alternatives that bypass the artifact. Use when screening cancer cell lines, diagnosing essentiality at amplified loci, choosing CRISPRcleanR / CERES / Chronos, deciding whether CN correction is needed before MAGeCK / BAGEL2 / drugZ, or switching from Cas9 to CRISPRi.
日本語の概要は準備中です。原文の説明を表示しています。
Quality control for pooled CRISPR screens covering library representation, Gini index, log-skew, replicate Pearson and Spearman concordance, essentialome precision-recall AUC against CEGv2 (Hart 2017), Cas9 cut-toxicity diagnostics, copy-number amplicon detection (Aguirre 2016 / Munoz 2016), bottleneck propagation through plasmid pool, infection, selection, and endpoint stages, MOI verification, and DepMap-style screen-quality scoring. Use when assessing screen quality before hit calling, deciding whether to repeat or rescue a screen, diagnosing low-confidence hits, choosing between MAGeCK / BAGEL2 / Chronos based on quality grade, picking a normalization strategy from QC signatures, or evaluating whether an in-vivo screen retained adequate library complexity.
日本語の概要は準備中です。原文の説明を表示しています。
Analyzes base-editing screens for variant function. Covers library design (Sanson 2020 GRACE, Hanna 2021 BRCA1/2 SNV scanning, Cuella-Martin 2021), CBE vs ABE chemistry choice (BE3/BE4 vs ABE7.10/ABE8.20/ABE8e), editing-window math (positions 4-8 from PAM-distal end, wider for ABE8e), bystander-edit quantification and the variant-call ambiguity it creates, sgRNA-efficiency filtering before hit calling, indel byproduct interpretation, the substitution-vs-indel diagnostic, variant annotation against ClinVar / COSMIC, and the Broad be-validation-pipeline. Use when designing a BE variant screen, choosing CBE vs ABE for a specific edit, interpreting bystander-confounded hits, distinguishing functional signal from indel artifact, integrating CRISPResso2 output with screen scoring, or deciding BE vs PE for SNV installation.
日本語の概要は準備中です。原文の説明を表示しています。
Identifies essential genes from CRISPR-Cas9 fitness screens using BAGEL2 (Kim & Hart 2021 Genome Med), a Bayesian classifier scoring per-gene Bayes Factors via log-likelihood ratios over per-sgRNA fold changes, calibrated against CEGv2 core-essentials (Hart 2017 G3, ~684 genes) and NEGv1 non-essentials (Hart 2014, ~927 genes). Covers the fc + bf + pr workflow, the linear-extrapolation improvement over BAGEL1 truncation, multi-target off-target correction, tumor-suppressor sensitivity (BAGEL2 detects enrichment), and BF-to-FDR calibration (BF >6 ≈ FDR 0.05 from Hart 2017). Use when classifying essential vs non-essential genes, calibrating BAGEL2 thresholds against PR curves, identifying tumor suppressors alongside essentials, comparing BAGEL2 hits to MAGeCK / drugZ, or generating publication-quality essentiality calls.
日本語の概要は準備中です。原文の説明を表示しています。
Cross-method decision tree for calling hits in pooled CRISPR screens. Catalogs statistical models (MAGeCK RRA, MAGeCK MLE, BAGEL2, drugZ, JACKS, Chronos, CERES), experimental designs each is built for, failure modes outside design domain, reconciliation when methods disagree, multiple-testing and effect-size thresholds, the order of operations (count -> QC -> CN-correct -> hit-call -> validate), the second-best-sgRNA conservative rule, and consensus-hit strategy. Use when choosing among MAGeCK / BAGEL2 / drugZ / JACKS / Chronos for a given design, reconciling disagreement across two or three methods on the same screen, deciding whether to require consensus, gating downstream validation by hit-confidence tier, or interpreting unstable hit lists across reruns.
日本語の概要は準備中です。原文の説明を表示しています。
Analyzes pooled CRISPR screens with MAGeCK (Li et al 2014), covering count generation (mageck count), the RRA two-condition workflow (mageck test using alpha-RRA over per-sgRNA negative-binomial p-values), the MLE multi-condition workflow (mageck mle with explicit design matrix and beta-score output), normalization choice (median vs total vs control-sgRNA vs spike-in), sgRNA efficiency injection, paired-sample testing, time-course design, drug-screen versus dropout-screen design matrices, MAGeCKFlute and MAGeCK-VISPR downstream visualization, and decision logic for when to use MAGeCK vs JACKS / BAGEL2 / drugZ / Chronos. Use when running a fresh CRISPR screen analysis, picking RRA vs MLE for the experimental design, choosing a normalization method from QC signatures, debugging MLE convergence failure or NaN beta scores, comparing MAGeCK output across tools, or building a batch-aware multi-cell-line / multi-condition MLE design matrix.
日本語の概要は準備中です。原文の説明を表示しています。
Designs pooled sgRNA libraries for CRISPR knockout, interference (CRISPRi), activation (CRISPRa), Cas12a multiplex, base-editor, and prime-editor screens. Covers on-target scoring (Rule Set 2, Azimuth, DeepSpCas9, CRISPRon), off-target scoring (CFD, MIT), TSS-relative positioning for CRISPRi/a (Horlbeck, Dolcetto, Calabrese), PAM-variant chemistries, control-guide composition, oligo cloning architecture, and library QC. Use when choosing a genome-wide library (GeCKOv2 vs Avana vs Brunello vs TKOv3 vs Inzolia), designing a focused or paralog-focused custom library, picking CRISPRi vs CRISPRa TSS windows, deciding control-guide proportions, or diagnosing library skew and dropout in a freshly cloned pool.
日本語の概要は準備中です。原文の説明を表示しています。
Fast headless browser for QA testing and site dogfooding. Navigate any URL, interact with elements, verify page state, diff before/after actions, take annotated screenshots, check responsive layouts, test forms and uploads, handle dialogs, and assert element states. ~100ms per command. Use when you need to test a feature, verify a deployment, dogfood a user flow, or file a bug with evidence. Use when asked to "open in browser", "test the site", "take a screenshot", or "dogfood this". (gstack)
日本語の概要は準備中です。原文の説明を表示しています。
Fast headless browser for QA testing and site dogfooding. Navigate pages, interact with elements, verify state, diff before/after, take annotated screenshots, test responsive layouts, forms, uploads, dialogs, and capture bug evidence. Use when asked to open or test a site, verify a deployment, dogfood a user flow, or file a bug with screenshots. (gstack)
日本語の概要は準備中です。原文の説明を表示しています。
Automates browser interactions for web testing, form filling, screenshots, and data extraction. Use when the user needs to navigate websites, interact with web pages, fill forms, take screenshots, test web applications, or extract information from web pages.
日本語の概要は準備中です。原文の説明を表示しています。
UI runtime 驗證 SKILL — 刷新 Cocos asset-db、執行 validate-ui-specs.js、headless-snapshot-test.js、capture-ui-screens.js，並依環境選用 cocos-screenshot 或 cocos-preview-qa 檢查實際畫面殘差，回寫 generated-review / runtime-verdict。USE FOR: 修改 layout / skin / screen / content / Panel / UI 資產後的驗證收尾。DO NOT USE FOR: 純資產生成、無 target 的整專案大範圍探索。
日本語の概要は準備中です。原文の説明を表示しています。
COMPLETE BUG INVESTIGATION WORKFLOW — Combines screenshot + log reading into a full triage pipeline. USE FOR: any bug report that has both visual symptoms AND runtime errors, especially CompositePanel / ChildPanel mount failures, screen spec wiring breaks, or battle scene UI crashes. This is the master debugging workflow that orchestrates cocos-screenshot and cocos-log-reader together.
日本語の概要は準備中です。原文の説明を表示しています。
BROWSER REVIEW QA SKILL — Use the built-in browser/headless browser (puppeteer-core) to open a browser-runnable Cocos preview, switch preview targets, capture screenshots, and compare them with reference images. USE FOR: screen-driven QA only when the user has already prepared a Browser Review environment that can run in the browser (`http://localhost:7456`, LoadingScene/preview host/preview target wiring ready). DO NOT USE FOR: current Cocos Editor window screenshots, Editor Preview capture, compile errors, or pure log analysis. If the Browser Review environment is not ready, stop and remind the user to prepare it first.
日本語の概要は準備中です。原文の説明を表示しています。
Identifies essential genes from CRISPR-Cas9 fitness screens using BAGEL2 (Kim & Hart 2021 Genome Med), a Bayesian classifier scoring per-gene Bayes Factors via log-likelihood ratios over per-sgRNA fold changes, calibrated against CEGv2 core-essentials (Hart 2017 G3, ~684 genes) and NEGv1 non-essentials (Hart 2014, ~927 genes). Covers the fc + bf + pr workflow, the linear-extrapolation improvement over BAGEL1 truncation, multi-target off-target correction, tumor-suppressor sensitivity (BAGEL2 detects enrichment), and BF-to-FDR calibration (BF >6 ≈ FDR 0.05 from Hart 2017). Use when classifying essential vs non-essential genes, calibrating BAGEL2 thresholds against PR curves, identifying tumor suppressors alongside essentials, comparing BAGEL2 hits to MAGeCK / drugZ, or generating publication-quality essentiality calls.
日本語の概要は準備中です。原文の説明を表示しています。
Analyzes pooled CRISPR screens with MAGeCK (Li et al 2014), covering count generation (mageck count), the RRA two-condition workflow (mageck test using alpha-RRA over per-sgRNA negative-binomial p-values), the MLE multi-condition workflow (mageck mle with explicit design matrix and beta-score output), normalization choice (median vs total vs control-sgRNA vs spike-in), sgRNA efficiency injection, paired-sample testing, time-course design, drug-screen versus dropout-screen design matrices, MAGeCKFlute and MAGeCK-VISPR downstream visualization, and decision logic for when to use MAGeCK vs JACKS / BAGEL2 / drugZ / Chronos. Use when running a fresh CRISPR screen analysis, picking RRA vs MLE for the experimental design, choosing a normalization method from QC signatures, debugging MLE convergence failure or NaN beta scores, comparing MAGeCK output across tools, or building a batch-aware multi-cell-line / multi-condition MLE design matrix.
日本語の概要は準備中です。原文の説明を表示しています。
Designs pooled sgRNA libraries for CRISPR knockout, interference (CRISPRi), activation (CRISPRa), Cas12a multiplex, base-editor, and prime-editor screens. Covers on-target scoring (Rule Set 2, Azimuth, DeepSpCas9, CRISPRon), off-target scoring (CFD, MIT), TSS-relative positioning for CRISPRi/a (Horlbeck, Dolcetto, Calabrese), PAM-variant chemistries, control-guide composition, oligo cloning architecture, and library QC. Use when choosing a genome-wide library (GeCKOv2 vs Avana vs Brunello vs TKOv3 vs Inzolia), designing a focused or paralog-focused custom library, picking CRISPRi vs CRISPRa TSS windows, deciding control-guide proportions, or diagnosing library skew and dropout in a freshly cloned pool.
日本語の概要は準備中です。原文の説明を表示しています。
Corrects the gene-independent copy-number artifact in CRISPR-Cas9 screens (Aguirre 2016 / Munoz 2016 Cancer Discov) where amplified loci appear essential from DNA-damage burden of simultaneous cuts. Covers the p53-dependent G2-arrest mechanism, CRISPRcleanR (Iorio 2018) unsupervised pre-hoc correction, CERES (Meyers 2017) joint CN + gene-effect model, Chronos (Dempster 2021) DepMap-standard population-dynamics + CN model with lowest residual bias, the decision tree by data availability, the Spearman LFC-vs-CN diagnostic, focal-amplification examples (ERBB2 in HER2+, MYC in colorectal, FGFR1 in head and neck), and CRISPRi/a alternatives that bypass the artifact. Use when screening cancer cell lines, diagnosing essentiality at amplified loci, choosing CRISPRcleanR / CERES / Chronos, deciding whether CN correction is needed before MAGeCK / BAGEL2 / drugZ, or switching from Cas9 to CRISPRi.
日本語の概要は準備中です。原文の説明を表示しています。
Quality control for pooled CRISPR screens covering library representation, Gini index, log-skew, replicate Pearson and Spearman concordance, essentialome precision-recall AUC against CEGv2 (Hart 2017), Cas9 cut-toxicity diagnostics, copy-number amplicon detection (Aguirre 2016 / Munoz 2016), bottleneck propagation through plasmid pool, infection, selection, and endpoint stages, MOI verification, and DepMap-style screen-quality scoring. Use when assessing screen quality before hit calling, deciding whether to repeat or rescue a screen, diagnosing low-confidence hits, choosing between MAGeCK / BAGEL2 / Chronos based on quality grade, picking a normalization strategy from QC signatures, or evaluating whether an in-vivo screen retained adequate library complexity.
日本語の概要は準備中です。原文の説明を表示しています。