「fact」の検索結果

Use when a task needs the judgment of a Business Teacher, Postsecondary — grading case analysis on the rigor of business reasoning rather than matching a single "correct" answer, updating stale textbook examples against current market conditions rather than teaching them as still-current, distinguishing taught analytical frameworks from personal business opinion presented as universal fact, and preserving the incomplete-information trade-offs of real business decisions rather than simplifying problems into false certainty.

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Use when a task needs the judgment of a biomedical/bioengineering engineer — running a design control phase (inputs, outputs, verification, validation) for a medical device, scoring a Design FMEA and deciding whether a failure mode needs mitigation, planning a human factors/usability validation study, building a design traceability matrix, or writing a design verification or risk-mitigation report. Distinct from a regulatory-affairs-specialist (owns the submission/clearance process, not the engineering itself) and from a clinical-data-manager/biostatistician (trial data and analysis, not device design).

日本語の概要は準備中です。原文の説明を表示しています。

Use when a task needs the judgment of an Architectural and Civil Drafter — setting up a CAD sheet at the correct scale and viewport scale factor, applying NCS/AIA layer and sheet-numbering standards, dimensioning a wall assembly or site plan per governing convention, managing xrefs and revision clouds across a sheet set, or QC-checking a drawing set before issuance.

日本語の概要は準備中です。原文の説明を表示しています。

Use when a task needs the judgment of an Administrative Law Judge, Adjudicator, or Hearing Officer — applying a mandatory sequential/structured evaluation framework in required order, weighing conflicting medical or vocational opinion evidence using specific regulatory factors, writing findings that explicitly address significant contrary evidence in the record, drafting a credibility/consistency finding tied to specific record citations, or checking whether a draft decision would survive substantial-evidence review.

日本語の概要は準備中です。原文の説明を表示しています。

Guide for using JASPAR transcription factor binding profiles with ENCODE ChIP-seq data. Use when users need to find TF binding motifs in ENCODE peaks, validate ChIP-seq targets with known motifs, or scan regulatory regions for TF binding potential. Trigger on: JASPAR, motif database, binding profile, PWM, position weight matrix, TF motif, motif enrichment, motif scanning, binding site prediction.

日本語の概要は準備中です。原文の説明を表示しています。

Integrate multiple ENCODE data types (RNA-seq, ATAC-seq, Histone ChIP-seq, TF ChIP-seq) for a tissue/cell type to build a comprehensive regulatory landscape. Use when the user wants to answer "what are the enhancers, promoters, and regulatory elements active in my tissue, and which transcription factors control them?" by layering expression, chromatin accessibility, histone marks, and TF binding data. Follows the Mawla et al. 2023 framework for cross-assay integration of islet cell type-specific data. Handles chromatin state annotation (ChromHMM), enhancer-gene linkage, TF motif enrichment, and cell type-specific regulatory element identification. Use for ANY multi-omic analysis, enhancer discovery, regulatory network construction, or epigenomic characterization using ENCODE data.

日本語の概要は準備中です。原文の説明を表示しています。

Guide for de novo and known motif enrichment analysis of ENCODE ChIP-seq and ATAC-seq peaks using HOMER and MEME Suite. Use when users need to discover TF binding motifs in peaks, validate ChIP-seq targets, or find co-binding partners. Trigger on: motif analysis, HOMER, MEME, de novo motif, motif enrichment, findMotifsGenome, AME, MEME-ChIP, known motif, TF binding motif, co-factor, motif discovery.

日本語の概要は準備中です。原文の説明を表示しています。

Find and work with ENCODE single-cell genomics data including scRNA-seq and scATAC-seq. Use when the user asks about single-cell experiments, cell type resolution, clustering from ENCODE data, deconvolution of bulk signals using single-cell references, or comparing single-cell vs bulk profiles. Covers platform differences (10X Chromium, Smart-seq2, Drop-seq), quality limitations of single-cell data, multimodal integration (RNA+ATAC), and cross-study reproducibility concerns. Also use for cell type annotation, gene detection limits, dropout artifacts, and single-cell data structure in ENCODE.

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Conduct rigorous cross-study meta-analysis of scRNA-seq data from ENCODE, integrating multiple single-cell transcriptomic datasets for a tissue/cell type. Use when the user wants to answer "what cell types exist in my tissue and what genes define them?" by combining scRNA-seq data across donors, labs, and platforms. Follows the Mawla et al. 2019 framework for assessing cross-study reproducibility, TIN-based quality filtering, and detection-limit-aware interpretation. Handles batch correction (Harmony/Seurat), dropout awareness, cross-contamination artifacts, and platform-specific biases. Use this skill for ANY scRNA-seq integration task, cross-dataset comparison, cell atlas construction, or reproducibility assessment involving ENCODE single-cell data.

日本語の概要は準備中です。原文の説明を表示しています。

Creates isolated git worktrees in .claude/worktrees/ with intelligent branch naming, auto-incrementing, and commit type detection (feat/fix/refactor). Supports manual descriptions and auto-generation from uncommitted git changes. Use when user requests to create worktree, start isolated work, parallel development, run /worktree command, or mentions "worktree".

日本語の概要は準備中です。原文の説明を表示しています。

Guide users through structured collaborative documentation creation. Use when user wants to write documentation, update README, create architecture docs, draft proposals, technical specs, decision docs, refactor documentation, create API docs, or document code.

日本語の概要は準備中です。原文の説明を表示しています。

Creates feature branches with optimized short naming, auto-incrementing, and commit type detection (feat/fix/refactor). Supports manual descriptions and auto-generation from uncommitted git changes. Use when user requests to create branch, start new branch, make branch, checkout new branch, switch branch, new task, start working on, begin work on feature, begin feature, create feature branch, run /create-branch command, or mentions "branch", "feature", "new feature", "feat", "fix", or "checkout".

日本語の概要は準備中です。原文の説明を表示しています。

Verify implementation matches OpenSpec change artifacts. Use when the user wants to validate that implementation is complete, correct, and coherent before archiving. Also use when the user says "openspec verify" or "opsx verify".

日本語の概要は準備中です。原文の説明を表示しています。

Propose a new OpenSpec change with all artifacts generated in one step. Use when the user wants to quickly describe what they want to build and get a complete proposal with design, specs, and tasks ready for implementation. Also use when the user says "openspec propose" or "opsx propose".

日本語の概要は準備中です。原文の説明を表示しています。

Survey any codebase as a senior advisor and produce prioritized, self-contained implementation plans for OTHER models/agents to execute. Strictly read-only on source code — never implements, fixes, or refactors anything itself. Use when asked to audit a codebase, find improvement opportunities (bugs, security, performance, test coverage, tech debt, migrations, DX), suggest features or where to take the project next (roadmap, product direction), or generate handoff plans for another agent to implement.

日本語の概要は準備中です。原文の説明を表示しています。

Strict test-driven development for behavior changes. Requires verified RED before production code, minimal GREEN, and refactor only after passing tests.

日本語の概要は準備中です。原文の説明を表示しています。

Proactive architecture review — explore codebase structure, generate a self-contained HTML report with Mermaid diagrams and candidate improvements, then grill the findings. Use when planning a large refactor, onboarding to an unfamiliar codebase, or before a major architectural change.

日本語の概要は準備中です。原文の説明を表示しています。

Create distinctive, production-grade frontend interfaces with high design quality. Use this skill when the user asks to build web components, pages, artifacts, posters, or applications (examples include websites, landing pages, dashboards, React components, HTML/CSS layouts, or when styling/beautifying any web UI). Generates creative, polished code and UI design that avoids generic AI aesthetics.

日本語の概要は準備中です。原文の説明を表示しています。

Serena code intelligence — LSP-powered symbol navigation, diagnostics, and targeted code surgery. Activate before complex refactors, cross-file analysis, or when graph tools need symbol-level depth.

日本語の概要は準備中です。原文の説明を表示しています。

Propose a new change with all artifacts generated in one step. Use when the user wants to quickly describe what they want to build and get a complete proposal with design, specs, and tasks ready for implementation.

日本語の概要は準備中です。原文の説明を表示しています。

Guidance for Tauri v2 production builds, signing, and distribution artifacts.

日本語の概要は準備中です。原文の説明を表示しています。

Iteratively study and apply elegant coding patterns. Each iteration - understand the code, research what simple and elegant code looks like, apply learnings, verify with CI. Use as a standalone refactoring pass or when the user asks to make code more elegant, simple, or idiomatic.

日本語の概要は準備中です。原文の説明を表示しています。

Audit code for correctness and rigor — logic errors, silent error swallowing, wishful thinking, and unjustified fallbacks. This is not a style review; it's a logic review. Use when you want a focused correctness audit separate from the full code-police pass.

日本語の概要は準備中です。原文の説明を表示しています。

Create distinctive, production-grade frontend interfaces with high design quality. Use this skill when the user asks to build web components, pages, artifacts, posters, or applications (examples include websites, landing pages, dashboards, React components, HTML/CSS layouts, or when styling/beautifying any web UI). Generates creative, polished code and UI design that avoids generic AI aesthetics.

日本語の概要は準備中です。原文の説明を表示しています。