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Establishes what something actually costs — fixed, variable and mixed cost behavior, absorption versus variable costing, job-order, process and activity-based methods, breakeven and operating leverage, and price/volume/mix decomposition. Use this to set a price floor, explain why revenue or margin moved, decide make versus buy, judge whether a product line earns its place, or work out how an allocation basis is distorting a reported margin.

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Generate Circos configuration files for circular genomics data visualization. Supports genomic variations (SNPs, CNVs, structural variants), cell-cell communication networks, and custom track configurations for publication-ready circular plots.

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Decompose genetic effects into direct and indirect paths through mediating variables using the mediation R package. Tests whether gene expression, methylation, or other molecular phenotypes mediate the effect of genetic variants on disease. Use when testing whether a molecular...

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Designs complete research plans that integrate clinical variables with multi-omics data from a user-provided biomedical direction. Always use this skill whenever a user wants to design, scope, or structure a study that combines clinical variables with transcriptomics, proteomics, metabolomics, epigenomics, or related omics layers for mechanism interpretation, biomarker development, risk stratification, treatment-response analysis, or translational use. It should define the clinical use case, alignment across data layers, feature-reduction and fusion logic, modeling route, mechanism-interpretation layer, validation ladder, and four workload configurations (Lite / Standard / Advanced / Publication+). Never fabricate datasets, accession numbers, sample counts, metadata completeness, platform coverage, literature references, PMIDs, DOIs, or validation status. Always include the mandatory Dataset Disclaimer immediately before any workflow section that mentions datasets or public resources.

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Use when constructing a prognosis nomogram from survival-related clinical predictors, exporting the nomogram bundle and C-index table, and optionally rendering the final nomogram PDF. NOT for: univariate/multivariable Cox feature screening, calibration curves, ROC analysis, decision-curve analysis, or non-survival outcomes.

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Use when evaluating Michael Burry-style contrarian, asymmetric, unpopular trades: deep mispricing, short theses, complex assets, forced consensus errors, and catalyst-driven downside/upside.

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Use when evaluating startups through a Founders Fund-style lens: contrarian conviction, hard tech, bold product ambition, non-consensus markets, and high-upside company building.

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Identify and verify loop invariants for correctness proofs

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Fresh adversarial code review with binary PASS/FAIL verdicts, evidence citations, and anchoring bias prevention via fresh reviewer spawning.

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Calculate the relative contribution of different factors to a response variable using R² decomposition. Use when you need to quantify how much each factor explains the variance of an outcome.

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Classify environmental and meteorological variables into driver categories for attribution analysis. Use when you need to group multiple variables into meaningful factor categories.

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Reduce dimensionality of multivariate data using PCA with varimax rotation. Use when you have many correlated variables and need to identify underlying factors or reduce collinearity.

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Für Klauselvarianten Vergleich: entwickelt Ziel, Vergleich und Eskalation; Ergebnis: Verhandlungs- oder Eskalationslinie.

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Für Abtretung: ordnet Norm, Beweislast und Gegenargument; Ergebnis: Prüfprodukt mit Risiko und nächstem Schritt. Fachgebiet: AGB-Recht-Prüfer. Route: abtretung-adversarial-test.

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Für Adversarial Test AGB: ordnet Norm, Beweislast und Gegenargument; Ergebnis: Prüfprodukt mit Risiko und nächstem Schritt.

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Implement game audio practice — bus/mixer architecture and gain in decibels, ducking (sidechain), adaptive/dynamic music via layering and re-sequencing, SFX variation, and beat synchronization. Engine-neutral. Use when the user mentions audio mixing, audio buses, adaptive/dynamic music, ducking, SFX variation, music layers, or syncing gameplay to the beat.

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Design a budget-vs-actuals tracker that stays alive past February — the category grain that matches real statements, the variance view that answers 'are we okay', the update ritual small enough to survive, and the honest handling of irregular expenses. Use when asked build me a budget spreadsheet, track team spend against budget, why do we always blow the budget invisibly, or design a household/project budget tracker. Produces the tracker structure, the variance logic, the irregulars ledger, and the monthly fifteen-minute ritual.

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Write platform-native paid ad copy with multiple angles to test. Use when asked to write ad copy, Google/Facebook/LinkedIn/Instagram ads, PPC headlines, or paid social creative copy. Produces ready-to-ship variants per platform (headlines, primary text, descriptions, CTAs) across distinct angles, sized to each platform's limits, with a note on what each variant tests.

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End-to-end composite that turns a single brief into voice-tuned X post variants, LinkedIn post variants, and a matching social graphic. Orchestrates create-x-content + create-linkedin-content + goose-graphics in one invocation. Asks about graphic format when not specified, with heuristic-driven recommendations.

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Draft voice-tuned LinkedIn post variants from a free-form brief. Reads a personal voice guide (generated via generate-voice-guide), produces 2–5 variants with distinct framings, applies LinkedIn-specific defaults (arrow bullets, "why this matters" beat, 150–500 words), and self-checks against the voice guide's banned phrases before returning.

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Draft voice-tuned X (Twitter) post variants from a free-form brief. Reads a personal voice guide (generated via generate-voice-guide), produces 2–5 variants with distinct framings (simple-howto, problem-first, hype, mechanism-breakdown, etc.), and self-checks against the voice guide's banned phrases before returning.

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Generate 3-5 messaging variants for a value proposition, design structured A/B tests, and analyze results to determine which framing resonates most with ICP. Tests can run via LinkedIn organic posts, cold email subject line splits, or both. Pure reasoning for variant generation and analysis — the user deploys the tests through their own tools. Use when a team can't decide between messaging angles and needs data, not opinions.

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Use the skill to control and verify the code interface configuration of your model — how Simulink® model elements are represented in the generated C or C++ code. This includes — (1) specifying names, types (storage classes), and placement of variables that represent model elements (for example, making a model parameter tunable as a global extern variable); (2) specifying names, types, and placement of functions that represent model algorithms; (3) selecting the deployment type (Component, Subcomponent, or Automatic); (4) selecting the interface configuration type (data or service interface); (5) linking a shared Embedded Coder dictionary to a model; (6) creating Embedded Coder dictionary entries and setting their properties; (7) for service interface configuration — specifying service interface definitions, including sender, receiver, client, and server services. Items 1 and 2 can be set per element or as a category-wide default. Item 1 applies to GRT and ERT models; the rest to ERT models only.

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Three modes for CS-conference papers (CVPR/ICCV/ECCV vision, ACL/EMNLP/NAACL NLP, ICLR/NeurIPS/ICML/AAAI ML). DIRECT-EDIT mode (common): the user describes a change in Chinese or English and the manuscript (LaTeX or Markdown) is edited directly through a CS-venue writing toolkit with author sign-off (use for 改这段 / 把中文想法写成 latex / polish / de-AI / translate / compress a passage). REVIEW mode (occasional, pre-submission): harden the paper through an adversarial courtroom review engine (N holistic domain reviewers / contestability routing / two-sided trial / three-way verdict / clerk-converged multi-round loop) with consensus-gated, author-signed revisions (use for review / critique / 审稿 / 评审 / mock-review). AUTO mode (unattended, opt-in via /goal): run the review-revise loop toward a verifiable goal, applying safe fixes under a drift-bounded policy and queueing risky ones. Resolves all inputs at runtime, no hardcoded paths. Not a from-scratch drafter (use ml-paper-writing) and not an official-venue rebuttal.

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