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概要と使いどころ
Predict RNA secondary structure, MFE folding, base-pair probabilities, RNA-RNA interactions via ViennaRNA Python bindings. Pipeline: sequence → MFE → partition function and pair-probability matrix → dot-bracket → duplex. Use for siRNA/sgRNA targeting, ribozyme design, RNA accessibility. Use RNAfold CLI for batch use without Python.
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WSI processing for digital pathology. Tissue detection, tile extraction (random, grid, score-based), filter pipelines for H&E/IHC. For dataset prep, tile-based DL, slide QC. Use pathml for multiplexed imaging.
日本語の概要は準備中です。原文の説明を表示しています。
3Dmol.js WebGL molecular visualization emitted as self-contained HTML. Render structures (PDB/SDF/XYZ/MOL2/cube) with stick, sphere, cartoon, line, and surface styles; animate trajectories with a frame-delay (interval, ms) control; and animate vibrational normal modes via vibrate() from per-atom dx/dy/dz displacements or from precomputed frames. Output standalone HTML that loads 3Dmol from a CDN, with optional play/pause and speed controls. Use for transition-state imaginary-mode animations, MD or reaction-path playback, docking poses, and orbital/density isosurfaces. For static 2D chemical structure drawings use rdkit-chemdraw-cdxml; for 2D statistical plots use matplotlib or plotly.
日本語の概要は準備中です。原文の説明を表示しています。
Computational pathology toolkit for whole-slide images (WSIs): load slides, extract tiles, stain normalization, nuclear segmentation, feature extraction, and ML training. Supports H&E and multiplex. For end-to-end pipelines from raw WSIs to quantitative outputs.
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Python library for single-particle tracking (SPT) in video microscopy via the Crocker-Grier algorithm. Locate particles (fluorescent spots, colloids, vesicles, cells) per frame, link into trajectories, filter short tracks, and compute MSD for diffusion analysis. 2D/3D with subpixel accuracy; reads TIF stacks, AVI, image series via pims. Use for quantitative SPT and diffusion coefficient extraction from fluorescence or brightfield video.
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Computer vision for bio-image preprocessing, feature detection, real-time microscopy. Color conversion, morphology, contour/blob detection, template matching, optical flow on fluorescence/brightfield. 10-100× faster than pure Python via C++. Use scikit-image for scientific morphometry/regionprops; OpenCV for real-time, video, classical feature extraction.
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Get insider trading activity (SEC Form 4 filings) for one or more stocks. Use when user asks about insider buying/selling, executive transactions, insider sentiment, or Form 4 activity.
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Fetch trade executions from Interactive Brokers filtered by account, date range, or symbol. Supports live API (~7 days history) and FlexReport (full history). Use when user asks about their trades, executions, or transaction history. Requires TWS or IB Gateway running locally.
日本語の概要は準備中です。原文の説明を表示しています。
Analyze C++ build performance using vcperf.exe and ETL traces. Use this skill when the user wants to profile a build, understand compile bottlenecks, identify expensive headers or templates, generate JSON analysis reports, or interpret vcperf output. Covers tracing workflows, the /jsonAnalysis flag, reading the resulting JSON schema, and actionable remediation strategies for each bottleneck category.
日本語の概要は準備中です。原文の説明を表示しています。
Comprehensive best practices, design patterns, and common pitfalls for ROS2 (Robot Operating System 2) development. Use this skill when building ROS2 nodes, packages, launch files, components, or debugging ROS2 systems. Trigger whenever the user mentions ROS2, colcon, rclpy, rclcpp, DDS, QoS, lifecycle nodes, managed nodes, ROS2 launch, ROS2 parameters, ROS2 actions, nav2, MoveIt2, micro-ROS, or any ROS2-era robotics middleware. Also trigger for ROS2 workspace setup, DDS tuning, intra-process communication, ROS2 security, or deploying ROS2 in production. Also trigger for colcon build issues, ament_cmake, ament_python, CMakeLists.txt for ROS2, package.xml dependencies, rosdep, workspace overlays, custom message generation, or ROS2 build troubleshooting. Covers Humble, Iron, Jazzy, and Rolling distributions.
日本語の概要は準備中です。原文の説明を表示しています。
Architecture patterns, design principles, and proven recipes for building robust robotics software. Use this skill when designing robot software architectures, choosing between behavioral frameworks, structuring perception-planning-control pipelines, implementing state machines, designing safety systems, or architecting multi-robot systems. Trigger whenever the user mentions behavior trees, finite state machines, subsumption architecture, sensor fusion, robot safety, watchdogs, heartbeats, graceful degradation, hardware abstraction layers, real-time constraints, or software architecture for robots. Also applies to sim-to-real transfer, digital twins, and robot fleet management.
日本語の概要は準備中です。原文の説明を表示しています。
Best practices, design patterns, and common pitfalls for ROS1 (Robot Operating System 1) development. Use this skill when building ROS1 nodes, packages, launch files, or debugging ROS1 systems. Trigger whenever the user mentions ROS1, catkin, rospy, roscpp, roslaunch, roscore, rostopic, tf, actionlib, message types, services, or any ROS1-era robotics middleware. Also trigger for migrating ROS1 code to ROS2, maintaining legacy ROS1 systems, or building ROS1-ROS2 bridges. Covers catkin workspaces, nodelets, dynamic reconfigure, pluginlib, and the full ROS1 ecosystem.
日本語の概要は準備中です。原文の説明を表示しています。
Persistent compounding memory for AI agents. 5 default MCP tools: session_start, session_end, remember, recall, check. Full surface: 6 tools with --full (adds check_action); 13 tools with AR_EXTRAS=1 --full. Two-verb model: inhale (session_start) and exhale (session_end). Correction-first memory with decision trail tracking, watch_for warnings, palace rooms with salience scoring, cross-project insight matching, same-day journal merging, ambient recall hooks. Local markdown only. Zero cloud, zero telemetry, Obsidian-compatible. Optional Supabase backend: when configured via `ar setup supabase`, recall() uses pgvector cosine similarity on OpenAI/Voyage embeddings instead of keyword search — same API, semantic understanding. Gracefully degrades to local search if not configured.
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Background context for the Electronic Bookkeeping Act (電子帳簿保存法) in the shinkoku tax filing plugin. Contains requirements for electronic bookkeeping, scanner storage, mandatory electronic transaction data storage, and shinkoku's compliance status. This skill is not user-invocable — Claude loads it automatically when responding to electronic bookkeeping compliance questions.
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Use when you need direct browser control - teaches Chrome DevTools Protocol for controlling existing browser sessions, multi-tab management, form automation, and content extraction via use_browser MCP tool
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Provides structured AWS cost optimization guidance using five pillars (right-sizing, elasticity, pricing models, storage optimization, monitoring) and twelve actionable best practices with executable AWS CLI examples. Use when optimizing AWS costs, reviewing AWS spending, finding unused AWS resources, implementing FinOps practices, reducing EC2/EBS/S3 bills, configuring AWS Budgets, or performing AWS Well-Architected cost reviews.
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Provides AWS CloudFormation patterns for Amazon Bedrock resources including agents, knowledge bases, data sources, guardrails, prompts, flows, and inference profiles. Use when creating Bedrock agents with action groups, implementing RAG with knowledge bases, configuring vector stores, setting up content moderation guardrails, managing prompts, orchestrating workflows with flows, and configuring inference profiles for model optimization.
日本語の概要は準備中です。原文の説明を表示しています。
Provides patterns and code examples for building Next.js 16+ applications with App Router architecture. Use when creating projects with App Router, implementing Server Components and Client Components ("use client"), creating Server Actions for forms, building Route Handlers (route.ts), configuring caching with "use cache" directive (cacheLife, cacheTag), setting up parallel routes (`@slot`) or intercepting routes, migrating to proxy.ts, or working with App Router file conventions (layout.tsx, page.tsx, loading.tsx, error.tsx).
日本語の概要は準備中です。原文の説明を表示しています。
Provides comprehensive patterns for deploying Next.js applications to production. Use when configuring Docker containers, setting up GitHub Actions CI/CD pipelines, managing environment variables, implementing preview deployments, or setting up monitoring and logging for Next.js applications. Covers standalone output, multi-stage Docker builds, health checks, OpenTelemetry instrumentation, and production best practices.
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Provides comprehensive code review capability for Next.js applications, validates Server Components, Client Components, Server Actions, caching strategies, metadata, API routes, middleware, and performance patterns. Use when reviewing Next.js App Router code changes, before merging pull requests, after implementing new features, or for architecture validation. Triggers on "review Next.js code", "Next.js code review", "check my Next.js app".
日本語の概要は準備中です。原文の説明を表示しています。
Provides authentication implementation patterns for Next.js 15+ App Router using Auth.js 5 (NextAuth.js). Use when setting up authentication flows, implementing protected routes, managing sessions in Server Components and Server Actions, configuring OAuth providers, implementing role-based access control, or handling sign-in/sign-out flows in Next.js applications.
日本語の概要は準備中です。原文の説明を表示しています。
Enables interaction with Google NotebookLM for advanced RAG (Retrieval-Augmented Generation) capabilities via the notebooklm-mcp-cli tool. Use when querying project documentation stored in NotebookLM, managing research notebooks and sources, retrieving AI-synthesized information, generating audio podcasts or reports from notebooks, or performing contextual queries against curated knowledge bases. Triggers on "notebooklm", "nlm", "notebook query", "research notebook", "query documentation in notebooklm".
日本語の概要は準備中です。原文の説明を表示しています。
Provides TypeScript patterns for DynamoDB-Toolbox v2 including schema/table/entity modeling, .build() command workflow, query/scan access patterns, batch and transaction operations, and single-table design with computed keys. Use when implementing type-safe DynamoDB access layers with DynamoDB-Toolbox v2 in TypeScript services or serverless applications.
日本語の概要は準備中です。原文の説明を表示しています。
Provides and generates complete CRUD workflows for Spring Boot 3 services. Creates feature-focused architecture with Spring Data JPA aggregates, repositories, DTOs, controllers, and REST APIs. Validates domain invariants and transaction boundaries. Use when modeling Java backend services, REST API endpoints, database operations, web service patterns, or JPA entities for Spring Boot applications.
日本語の概要は準備中です。原文の説明を表示しています。