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5W1H Decision Framework Tool. Use for: (1) Systematic decision-making before creating todos, (2) Preventing duplicate implementation, (3) Detecting avoidance behavior, (4) Ensuring agile refactor compliance with executor/dispatcher separation

日本語の概要は準備中です。原文の説明を表示しています。

Execute Abridge production readiness checklist for clinical AI deployment. Use when launching Abridge in a healthcare org, preparing for go-live, or validating HIPAA compliance before production deployment. Trigger: "abridge production checklist", "abridge go-live", "abridge launch readiness", "abridge prod deploy".

日本語の概要は準備中です。原文の説明を表示しています。

Run a health check on an existing project: dependency audit, security scan, test runner detection, CI/CD evaluation, and missing configuration analysis. Maps the three execution gates (pre/in/post) from /10x-bootstrapper to an assessment framework for existing codebases. Reads optional context/foundation/stack-assessment.md from /10x-stack-assess to focus checks on identified gaps. Writes context/foundation/health-check.md with findings, prioritized fixes, and an agent-readiness verdict. Use when the user has an existing project and wants to verify its health before working with an agent. Trigger phrases: "health check", "check my project", "audit my project", "is my project healthy", "sprawdź projekt", "audyt projektu", "health-check", "project health". Use AFTER /10x-stack-assess (brownfield chain), BEFORE agent onboarding (m1-l4).

日本語の概要は準備中です。原文の説明を表示しています。

Use when continuing implementation from an existing plan

日本語の概要は準備中です。原文の説明を表示しています。

Use when starting feature work that needs isolation from current workspace or before executing implementation plans - ensures an isolated workspace exists via native tools or git worktree fallback

日本語の概要は準備中です。原文の説明を表示しています。

INTERNAL/HELPER skill — do NOT invoke directly from a user query. This is the shared formatter/poster used by breakdown-issues. It formats a scope GitHub Issue body (label cc-triage-scope, used before code analysis), runs the pre-posting checklist, and executes `gh issue create`. Invoke this skill ONLY from one of the parent skills via the Skill tool, after the parent has finalized the task breakdown. If a user asks to 'create a scope issue' or similar, route them to the parent skill (/breakdown-issues) rather than invoking this one directly.

日本語の概要は準備中です。原文の説明を表示しています。

INTERNAL/HELPER skill — do NOT invoke directly from a user query. This is the shared formatter/poster used by create-issue, create-issue-from-issue-number, and update-issue. It formats an implementation-ready GitHub Issue body, runs the pre-posting checklist, executes `gh issue create` or `gh issue edit`, and optionally posts a 確認事項 follow-up comment. Invoke this skill ONLY from one of the three parent skills via the Skill tool, after the parent has completed analysis. If a user asks to 'format an issue body' or similar, route them to the appropriate parent skill (/create-issue, /create-issue-from-issue-number, or /update-issue) rather than invoking this one directly.

日本語の概要は準備中です。原文の説明を表示しています。

Segment single cells from multiplexed IMC/MIBI tissue images using Mesmer/DeepCell, Cellpose, or ilastik+CellProfiler, covering whole-cell vs nuclear segmentation, the summed-membrane-channel decision, nuclear-expansion bias, lateral spillover, resolution-floor parameters, and downstream-proxy evaluation. Use when delineating cells after preprocessing, choosing a segmentation model, building a cell mask for quantification, diagnosing impossible double-positive populations, or troubleshooting over/under-segmentation.

日本語の概要は準備中です。原文の説明を表示しています。

Reads, queries, and writes bigWig indexed binary signal tracks (coverage, fold-change, conservation, methylation-rate) with pyBigWig (Python) and the UCSC Kent tools (bedGraphToBigWig, bigWigToBedGraph, bigWigInfo, bigWigSummary, bigWigAverageOverBed) and deepTools (multiBigwigSummary, computeMatrix, bigwigCompare). Covers the central trap that a wide query returns a precomputed zoom-level summary (by default the mean, which annihilates narrow peaks) not per-base data, when exact=True/values() is mandatory, the NaN-not-zero gap-handling fork, choosing mean vs max vs sum vs coverage by biological question, and the sorted-bedGraph plus chrom.sizes build requirement. Use when extracting signal at regions, computing mean signal per gene/peak, building a browser track from bedGraph, comparing tracks, or building TSS/gene-body metaprofiles.

日本語の概要は準備中です。原文の説明を表示しています。

Designs genomics experiments so technical nuisance variation (batch, lane, plate, flow cell, operator, reagent lot, processing day) is balanced against the biological variable of interest and therefore estimable rather than confounded, using constrained sample-to-batch assignment (designit, OSAT), the confounder/mediator/collider distinction, and the principle that no post-hoc correction recovers a fully confounded design. Covers detecting hidden batches with surrogate variable analysis, a decision table for downstream correction (ComBat-seq, RUVSeq, SVA) whose execution is deferred to differential-expression/batch-correction, and reproducibility metadata. Use when assigning samples to sequencing batches/lanes/plates, avoiding batch-condition confounding, deciding whether a design is salvageable by correction, choosing a correction method, or estimating the number of hidden batches. For the experimental unit, randomization, and blocking concepts see experimental-design/randomization-blocking.

日本語の概要は準備中です。原文の説明を表示しています。

Delimits putative species boundaries from molecular data within the de Queiroz 2007 unified-lineage framework using ASAP (Puillandre 2021 successor to ABGD), mPTP C++ (Kapli 2017 successor to bPTP; bPTP is Python NOT R), GMYC single/multi-threshold (Pons 2006; Fujisawa 2013), multilocus BPP v4 with prior calibration from data (NOT defaults; Yang 2015), SNAPP + BFD* for SNP delimitation, DELINEATE (Sukumaran 2021) speciation-process modeling to address Sukumaran & Knowles 2017 PNAS critique that MSC delimits structure not species, integrative-taxonomy congruence (Padial 2010; Carstens 2013), Dsuite for introgression testing before sister claims (Malinsky 2021), and Meyer & Paulay 2005 barcoding-gap-absence caveat. Use when delineating species from DNA barcoding data, resolving cryptic complexes, choosing among ASAP/mPTP/BPP/DELINEATE, calibrating BPP priors, distinguishing introgression from ILS, or applying the Sukumaran-Knowles oversplitting correction.

日本語の概要は準備中です。原文の説明を表示しています。

Performs ML-based protein-ligand pose prediction and scoring using DiffDock-L (diffusion-based), Boltz-1 / Boltz-2 (foundation model with affinity), Chai-1, AlphaFold3 ligand, EquiBind, TANKBind, NeuralPLexer, and hybrid workflows (DiffDock pose + GNINA rescore + PoseBusters QC). Explicit handling of when ML beats classical docking, when classical beats ML, the PB-invalid pose problem, and rescoring as the standard production hybrid. Use when modern docking is needed: foundation-model ligand-pose prediction, AI rescoring of classical poses, or scaffold-hopping in cross-docking scenarios.

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Validates docked / generated protein-ligand poses using PoseBusters physical-validity tests, strain energy quantification, geometric checks (planarity, vdW overlap, bond/angle distortion), and pose-energy reasonableness. Filters AI-docking outputs (DiffDock, EquiBind, NeuralPLexer) where ~50% of poses fail physical-validity tests. Use when QC-ing docking results, comparing classical vs ML docking outputs, or filtering pose lists before SAR analysis.

日本語の概要は準備中です。原文の説明を表示しています。

Audit required bioinformatics command-line tools against Lmod or Environment Modules on Linux HPC clusters, resolve executable and version requirements, and reproducibly deploy missing software through a site-approved EasyBuild, Spack, Bioconda/micromamba, Apptainer, binary, or source-build workflow. Use when Codex must inspect module availability, diagnose a missing or wrong-version bioinformatics tool, install scientific software on Slurm/PBS clusters, publish or validate modulefiles, or produce an auditable and rollback-ready cluster software deployment.

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Track and report progress of a request to create and run an EcoSIM case for a site ("create an ecosim run for site US-UMB", "set up and run EcoSIM at <site>"). Records four stages — data preparation, namelist creation, model simulation, and output evaluation — in result/<SITE_ID>/progress.json and PROGRESS.md, derives step status from files and quality reports on disk, and records manual results such as the executable, test run, and evaluation verdicts. Use at the start of such a request, after each stage, and whenever the user asks where a site run stands.

日本語の概要は準備中です。原文の説明を表示しています。

Plan purple-team / adversary-simulation exercises against systems you are contracted to test. High-level objectives and detection gaps only. No live attack procedures or payloads.

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Generates strictly typed Drizzle ORM schemas for PostgreSQL with indexes, foreign keys, and Zod schema deduction.

日本語の概要は準備中です。原文の説明を表示しています。

Plan and execute Convex schema migrations safely, including adding fields, creating tables, and data transformations. Use when schema changes affect existing data.

日本語の概要は準備中です。原文の説明を表示しています。

Design and generate Convex database schemas with proper validation, indexes, and relationships. Use when creating schema.ts or modifying table definitions.

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Prepare a private handoff to continue a task in Claude Code, Codex, or another agent; resume from an existing handoff without changing Git or executing its commands automatically. Use for "continue in Codex", "pasar a Claude", "migrar esta sesión", or "retomar este handoff".

日本語の概要は準備中です。原文の説明を表示しています。

Optimize Bazel builds for large-scale monorepos. Use when configuring Bazel, implementing remote execution, or optimizing build performance for enterprise codebases.

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Turn a one-line objective into a step-by-step construction plan any coding agent can execute cold. Each step has a self-contained context brief — a fresh agent in a new session can pick up any step without reading prior steps.

日本語の概要は準備中です。原文の説明を表示しています。

Azure Monitor Query SDK for Java. Execute Kusto queries against Log Analytics workspaces and query metrics from Azure resources.

日本語の概要は準備中です。原文の説明を表示しています。

Azure AI Projects SDK for Java. High-level SDK for Azure AI Foundry project management including connections, datasets, indexes, and evaluations.

日本語の概要は準備中です。原文の説明を表示しています。