Plan, execute, and document validation, verification, and transfer of analytical procedures under the governing framework - ICH Q2(R2) and Q14, USP <1220>/<1225>/<1226>, ICH M10 bioanalytical, CLSI EP, or ISO/IEC 17025. Use for HPLC, LC-MS/MS, GC, CE, ICP-MS, dissolution, qNMR, qPCR, NIR, and ligand binding or cell-based assays whenever the question is whether a procedure is fit for its intended purpose. Triggers include "method validation", "analytical method validation", "AMV", "validation protocol", "acceptance criteria", "linearity", "reportable range", "accuracy and precision", "repeatability", "intermediate precision", "recovery", "LOD", "LOQ", "detection limit", "quantitation limit", "specificity", "robustness", "method transfer", "method comparison", "Deming", "Passing-Bablok", "Bland-Altman", "equivalence testing", "OOS investigation", "ICH Q2", "Q2(R2)", "Q14", "USP 1225", "ICH M10", "incurred sample reanalysis", "ISR", "CLSI EP", and any request to show that an assay works.
日本語の概要は準備中です。原文の説明を表示しています。
bg-szy/TOP-SKILLS☆ 62026年9月8日 更新
Multi-perspective academic paper review with dynamic reviewer personas. Runs a 5-seat, role-separated review panel (Journal-Fit Reviewer + 3 peer-review roles + Devil's Advocate) with field-specific expertise; role separation is not a claim of independent error processes. Supports full review, re-review (verification), quick assessment, methodology focus, Socratic guided, and calibration modes. Triggers on: review paper, peer review, manuscript review, referee report, review my paper, critique paper, simulate review, editorial review, calibrate reviewer, reviewer calibration, measure reviewer accuracy, 審查論文, 論文審查, 模擬審查, 同儕審查, 幫我審這篇, 以審查人角度評估, 審查者校準, 논문 심사, 동료 심사, 모의 심사, 심사자 관점에서 평가, 심사자 보정.
日本語の概要は準備中です。原文の説明を表示しています。
bg-szy/TOP-SKILLS☆ 62026年9月8日 更新
Trains and fine-tunes vision models for object detection (D-FINE, RT-DETR v2, DETR, YOLOS), image classification (timm models — MobileNetV3, MobileViT, ResNet, ViT/DINOv3 — plus any Transformers classifier), and SAM/SAM2 segmentation using Hugging Face Transformers on Hugging Face Jobs cloud GPUs. Covers COCO-format dataset preparation, Albumentations augmentation, mAP/mAR evaluation, accuracy metrics, SAM segmentation with bbox/point prompts, DiceCE loss, hardware selection, cost estimation, Trackio monitoring, and Hub persistence. Use when users mention training object detection, image classification, SAM, SAM2, segmentation, image matting, DETR, D-FINE, RT-DETR, ViT, timm, MobileNet, ResNet, bounding box models, or fine-tuning vision models on Hugging Face Jobs.
日本語の概要は準備中です。原文の説明を表示しています。
bg-szy/TOP-SKILLS☆ 62026年9月8日 更新
Validate documentation before merging - check completeness, broken links, code example accuracy, and factual correctness. Use when reviewing docs for quality gates or running pre-merge doc validation.
日本語の概要は準備中です。原文の説明を表示しています。
bg-szy/TOP-SKILLS☆ 62026年9月8日 更新
Multi-perspective academic paper review with dynamic reviewer personas. Simulates 5 independent reviewers (EIC + 3 peer reviewers + Devil's Advocate) with field-specific expertise. Supports full review, re-review (verification), quick assessment, methodology focus, Socratic guided, and calibration modes. Triggers on: review paper, peer review, manuscript review, referee report, review my paper, critique paper, simulate review, editorial review, calibrate reviewer, reviewer calibration, measure reviewer accuracy.
日本語の概要は準備中です。原文の説明を表示しています。
bouclem/skills☆ 62026年5月31日 更新
Ultra-compressed communication mode that cuts output tokens while keeping technical accuracy. Levels: lite, full, ultra and the wenyan variants. Use for /caveman, "caveman mode", "talk like caveman", "be brief" or "less tokens".
日本語の概要は準備中です。原文の説明を表示しています。
AndrewBrown-USDA/aigb-skills-usda☆ 52026年10月10日 更新
Normalizes documentation and examples for consistency in style, format, and accuracy. Ensures code matches existing patterns and documentation. Use when reviewing docs, examples, or writing new code that should follow established patterns.
日本語の概要は準備中です。原文の説明を表示しています。
AndrewBrown-USDA/aigb-skills-usda☆ 52026年10月10日 更新
Create new skills, modify and improve existing skills, and measure skill performance. Use when users want to create a skill from scratch, edit, or optimize an existing skill, run evals to test a skill, benchmark skill performance with variance analysis, or optimize a skill's description for better triggering accuracy.
日本語の概要は準備中です。原文の説明を表示しています。
garochee33/DSH☆ 42026年10月12日 更新
Create new skills, modify and improve existing skills, and measure skill performance. Use when users want to create a skill from scratch, edit, or optimize an existing skill, run evals to test a skill, benchmark skill performance with variance analysis, or optimize a skill's description for better triggering accuracy.
日本語の概要は準備中です。原文の説明を表示しています。
0xAidan/polymarket-bot-test☆ 42026年9月4日 更新
Discover governing equations from data using PySR (evolutionary symbolic regression). Physics-constrained search with dimensional analysis, custom operators, and complexity-accuracy tradeoffs. Use when you need an interpretable equation, not a black-box model.
日本語の概要は準備中です。原文の説明を表示しています。
huang-sh/DeepScience☆ 42026年7月15日 更新
Parameter-efficient fine-tuning for LLMs using LoRA, QLoRA, and 25+ methods. Use when fine-tuning large models (7B-70B) with limited GPU memory, when you need to train <1% of parameters with minimal accuracy loss, or for multi-adapter serving. HuggingFace's official library integrated with transformers ecosystem.
日本語の概要は準備中です。原文の説明を表示しています。
huang-sh/DeepScience☆ 42026年7月15日 更新
Reduce LLM size and accelerate inference using pruning techniques like Wanda and SparseGPT. Use when compressing models without retraining, achieving 50% sparsity with minimal accuracy loss, or enabling faster inference on hardware accelerators. Covers unstructured pruning, structured pruning, N:M sparsity, magnitude pruning, and one-shot methods.
日本語の概要は準備中です。原文の説明を表示しています。
huang-sh/DeepScience☆ 42026年7月15日 更新
Post-training 4-bit quantization for LLMs with minimal accuracy loss. Use for deploying large models (70B, 405B) on consumer GPUs, when you need 4× memory reduction with <2% perplexity degradation, or for faster inference (3-4× speedup) vs FP16. Integrates with transformers and PEFT for QLoRA fine-tuning.
日本語の概要は準備中です。原文の説明を表示しています。
huang-sh/DeepScience☆ 42026年7月15日 更新
Quantizes LLMs to 8-bit or 4-bit for 50-75% memory reduction with minimal accuracy loss. Use when GPU memory is limited, need to fit larger models, or want faster inference. Supports INT8, NF4, FP4 formats, QLoRA training, and 8-bit optimizers. Works with HuggingFace Transformers.
日本語の概要は準備中です。原文の説明を表示しています。
huang-sh/DeepScience☆ 42026年7月15日 更新
Performs alchemical free-energy calculations including relative binding free energy (RBFE / FEP+) and absolute binding free energy (ABFE) via OpenFE, FEP+, GROMACS, AMBER pmemd, and OpenMM with explicit lambda window scheduling, soft-core potentials, REST2 enhanced sampling, MBAR/BAR analysis, and cycle closure validation. Compares ML alternatives (Boltz-2 affinity, DeepDock). Use when ranking analogs by binding affinity beyond docking accuracy, performing prospective lead optimization, or validating SAR predictions.
日本語の概要は準備中です。原文の説明を表示しています。
huang-sh/DeepScience☆ 42026年7月15日 更新
Evaluates and implements age estimation and verification technologies for online services. Covers facial age estimation, digital ID verification, self-declaration with risk assessment, AI-based age estimation, and the accuracy versus privacy tradeoff. Includes ICO guidance and euCONSENT framework. Keywords: age verification, age estimation, facial analysis, digital ID, children, online safety.
日本語の概要は準備中です。原文の説明を表示しています。
aibot88/sec_skill_store☆ 42026年5月27日 更新
Interactive cell annotation and image QC for IMC/MIBI using napari, napari-imc, Mantis Viewer, and cytomapper, covering the pixels-to-cell-table bridge, overlaying masks to catch segmentation/spillover artifacts, inter-annotator variability as the accuracy ceiling, contrast-as-threshold, and building class-balanced ground-truth label sets. Use when manually labeling cells, generating training data for a classifier, QC-ing segmentation on the image, confirming clusters are spatially real, or choosing an annotation viewer.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/TRACE☆ 32026年10月11日 更新
Predict peptide-MHC class II (HLA-DR/DQ/DP) binding and presentation for CD4 T-cell epitopes with NetMHCIIpan-4.3 and MixMHC2pred-2.0. Covers why class II is far less reliable than class I (open binding groove, 9-mer register ambiguity, sparse noisy training data, DR>DP>DQ accuracy asymmetry), the DQ/DP heterodimer alpha/beta pairing trap, and the looser 1%/5% %Rank thresholds. Use when predicting CD4 epitopes for vaccine help, mapping class II neoantigens, or scoring long peptides against DR/DQ/DP. For CD8/class I see mhc-binding-prediction.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/TRACE☆ 32026年10月11日 更新
Decides whether and how to polish a draft genome assembly to raise consensus accuracy (QV) with read-type-matched tools - Racon and medaka (ONT consensus), dorado polish, Polypolish and pypolca (Illumina, repeat-aware), Pilon (legacy short-read), NextPolish/NextPolish2, Hapo-G (haplotype-aware), ntEdit, and DeepPolisher/PEPPER-Margin-DeepVariant for human. Covers the do-not-polish-HiFi rule, the medaka basecaller-model footgun, held-out Merqury QV as the only honest stop signal, and the haplotype-collapse trap. Use when correcting homopolymer indels or residual SNPs in a long-read assembly, deciding if a HiFi assembly needs polishing, or choosing an ONT vs hybrid vs short-read polishing chain.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/TRACE☆ 32026年10月11日 更新
Performs alchemical free-energy calculations including relative binding free energy (RBFE / FEP+) and absolute binding free energy (ABFE) via OpenFE, FEP+, GROMACS, AMBER pmemd, and OpenMM with explicit lambda window scheduling, soft-core potentials, REST2 enhanced sampling, MBAR/BAR analysis, and cycle closure validation. Compares ML alternatives (Boltz-2 affinity, DeepDock). Use when ranking analogs by binding affinity beyond docking accuracy, performing prospective lead optimization, or validating SAR predictions.
日本語の概要は準備中です。原文の説明を表示しています。
peacezha/TRACE☆ 32026年10月11日 更新
Ultra-compressed communication mode. Cuts token usage ~75% by speaking like caveman while keeping full technical accuracy. Supports intensity levels: lite, full (default), ultra, wenyan-lite, wenyan-full, wenyan-ultra. Use when user says "caveman mode", "talk like caveman", "use caveman", "less tokens", "be brief", or invokes /caveman. Also auto-triggers when token efficiency is requested.
日本語の概要は準備中です。原文の説明を表示しています。
lgzarturo/springboot-course☆ 32026年10月12日 更新
Create new skills, modify and improve existing skills, and measure skill performance. Use when users want to create a skill from scratch, edit, or optimize an existing skill, run evals to test a skill, benchmark skill performance with variance analysis, or optimize a skill's description for better triggering accuracy.
日本語の概要は準備中です。原文の説明を表示しています。
sebastianbreguel/dotfiles☆ 32026年10月8日 更新
Ultra-compressed communication mode. Cuts token usage ~75% by dropping filler, articles, and pleasantries while keeping full technical accuracy. Use persistent mode only when user says "caveman mode", "talk like caveman", "use caveman", or invokes /caveman.
日本語の概要は準備中です。原文の説明を表示しています。
heyAyushh/stacc☆ 32026年9月21日 更新
Ultra-compressed communication mode. Cuts token usage ~75% by dropping filler, articles, and pleasantries while keeping full technical accuracy. Use when user says "caveman mode", "talk like caveman", "use caveman", "less tokens", "be brief", or invokes /caveman.
日本語の概要は準備中です。原文の説明を表示しています。
heyAyushh/stacc☆ 32026年9月21日 更新