「boundary」の検索結果

Defines cell populations in flow and spectral cytometry through manual gates (rectangle, polygon, quadrant, boolean) and reproducible automated gating (openCyto gating templates, flowDensity data-driven thresholds, flowClust model-based gates), organized as a hierarchical GatingSet (flowWorkspace) and round-tripped with FlowJo via CytoML. Covers the canonical gate order (time -> debris -> singlets -> live -> lineage), FMO-vs-isotype boundary setting, gate-order dependence and recompute semantics, rare-event/MRD gating, and per-population statistics. Use when building a gating strategy, automating a manual FlowJo scheme across samples, choosing manual vs data-driven gates, or extracting population frequencies.

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Quality control for flow, spectral, and mass cytometry - time-based anomaly cleaning (flowAI, flowCut, PeacoQC, flowClean), margin/boundary event removal, signal-drift detection, dead-cell exclusion, CyTOF Gaussian/DNA/event-length checks, instrument calibration/standardization (MESF, CS&T, peak-2), and batch-level outlier flagging. Use when assessing acquisition quality, choosing a cleaning tool, ordering QC relative to compensation, deciding margin removal before density-based steps, or flagging problematic samples before clustering or differential analysis.

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Handles batch effects in bulk RNA-seq via design-matrix inclusion (the correct path for DE), ComBat/ComBat-seq for visualization, SVA for unknown latent factors, RUVSeq for negative-control-gene-anchored unwanted variation, and limma::removeBatchEffect for plotting only. Encodes the Nygaard 2016 cardinal sin against testing on a batch-corrected matrix, the choice between SVA/RUVg/RUVs/RUVr, the confounding non-identifiability problem, the single-cell boundary (Harmony/MNN are NOT for bulk), and the Goh 2017 harmonization critique. Use when designing a DE analysis with batch structure, troubleshooting batch-dominated PCA, choosing ComBat vs ComBat-seq, handling unknown batch via SVA, integrating across studies, or deciding when (rarely) to subtract batch.

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Preflight a spec draft without saving. Runs the same checks as the write-boundary hooks — PlantUML syntax, required diagram presence, AC-to-sequence traceability, Design calls quality floor, and System delta row resolution — and prints a compact pass/fail table. Use while iterating so the hooks don't bite on save.

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The primary tool for code-navigation questions in ANY language (frontend or backend) — walk the structural graph from an entry point (page, route, handler, command, `main`) down through imports to the IO boundary (network call, query, file read). Use this skill, in preference to the Explore agent or global grep, whenever the user asks "where does X come from?", "what API/data populates Y?", "what renders or wraps the Z panel?", "which file for feature F?", "how is this wired up?", or any code-navigation question mapping a UI element, route, or feature concept to source files. Also reverse queries ("what uses /api/foo?", "who consumes this service?"). Keyword search routinely picks up unrelated flows sharing a domain word and produces wrong answers; the walk follows the actual graph. The JS/TS `walk.mjs`/`discover.mjs` are an optional accelerator, not required — the walk is language-agnostic.

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Design error handling strategies for TypeScript and Python applications — exception hierarchies, Result/Either types, retry patterns, error boundaries, and structured error logging. Use when designing error handling architecture, choosing between exceptions and Result types, implementing retry logic, or building error recovery flows. Activate on "error handling", "exception hierarchy", "Result type", "retry pattern", "circuit breaker", "error boundary", "Pokemon exception". NOT for debugging specific runtime errors, logging infrastructure setup, or monitoring/alerting configuration.

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Runtime enforcement of file system boundaries and tool access restrictions. Blocks unauthorized operations and logs violations. Activate on 'enforce scope', 'access control', 'boundary enforcement', 'tool restrictions', 'runtime security'. NOT for validation (use dag-permission-validator) or isolation management (use dag-isolation-manager).

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Diagnose when intuitive judgment, agent confidence, or expert routing can be trusted by classifying environment validity, feedback quality, and task-boundary fit. Use for confidence calibration, agent routing, expertise audits, and escalation design. NOT for deterministic implementation tasks, pure syntax debugging, or domains with explicit verifiable answers.

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Implement and finalize one ready rolling-wave slice in one invocation while preserving the lifecycle boundary between implementation and independent review. Use when the user wants a slice delivered end to end without manually invoking implement-slice and finalize-slice, wants main-local implementation by default with workers only when delegation pays, followed by mandatory fresh-context finalization, or says deliver, implement and finalize, or take the slice through review.

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Walk every branching path and boundary condition in content, report only unhandled edge cases. Orthogonal to adversarial review - method-driven not attitude-driven. Use when you need exhaustive edge-case analysis of code, specs, or diffs.

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Use BEFORE writing any test — enumerate cases per behavior (happy / boundary / error / abuse), prioritize by likelihood × impact, cross-check via subagent — even if the user just says 'add tests'.

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Use when shaping a Livewire component before code — full-page vs partial, parent/child split, event flow, state-vs-props boundary, hydration cost — even on 'add this Livewire component'.

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When writing validation — Form Requests, rules, custom rule objects, request-boundary design — even when the user just says 'validate this input' or 'check the request' without naming it.

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Design, implement, and integrate generalized validation harnesses across a producer-consumer boundary after a local harness contract exists. Use when refactoring custom validation CLIs/MCPs for large polyrepos, extending Steward across sibling repos, or deploying a local tool to a consumer project for dogfooding and testing; use mcp-harness-repo-maintainer first for initial steward.yaml adoption and cold-start proof.

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Establish or audit a structural quality contract for any agent-operated engineering repository: app, library, CLI/tool, plugin, harness, or meta repo. Use when a repo needs charter clarity, docs/decision ownership, type-native validation gates, evidence paths, safe action policy, cold-start legibility, maturity proof, repair-loop routing, consumer/producer owner-boundary routing, command surface evolution, evolutionary simplicity (see references/evolutionary-simplicity.md), or a repo ecology pass to decide what should be compressed, merged, removed, updated, created, retired, or moved to checks.

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SOP for the micro-execution C.O.R.E. phase. Trigger when: - Implementing plan steps, managing code changes at commit boundaries, and verifying incremental progress. - Navigating states: Absorb, Clarify, Plan, Execute. - Prompt contains: /core, core workflow, absorb, clarify, execution invariants, commit boundary, verify assertion.

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Volatility-based decomposition review. Trigger when: - Evaluating module boundaries against axes of change and business volatility. - Prompt contains: /lowy, volatility, axis of change, design decomposition, boundary.

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Builds reusable Convex components with isolated tables and app-facing APIs. Use for new components, reusable backend modules, integrations, or component boundary work.

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Builds reusable Convex components with isolated tables and app-facing APIs. Use for new components, reusable backend modules, integrations, or component boundary work.

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Detect cyber attacks targeting OT historian servers (OSIsoft PI, Ignition, Wonderware) that sit at the IT/OT boundary and serve as pivot points for lateral movement between enterprise and control networks, including data manipulation, unauthorized queries, and exploitation of historian-specific vulnerabilities.

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Prepare a defense-contractor environment for CMMC Level 2 certification: scope CUI and FCI, implement the 110 NIST SP 800-171 Rev 2 security requirements across 14 families, compute the SPRS score with the DoD Assessment Methodology, manage a compliant POA&M, and ready the organization for a C3PAO assessment. Use when an organization handles Controlled Unclassified Information (CUI) under a DoD contract, when a contract carries DFARS clause 252.204-7012/7019/7020/7021, when preparing for or responding to a CMMC assessment, when computing or improving an SPRS score, when building a System Security Plan or POA&M for 800-171, or when scoping which systems are in the CUI boundary. Keywords: CMMC, CMMC Level 2, NIST 800-171, SP 800-171 Rev 2, CUI, FCI, SPRS, DFARS 7012, C3PAO, POA&M, System Security Plan, DoD Assessment Methodology, 110 controls, defense industrial base, DIB, FedRAMP equivalency.

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Review storage placement across framework global data, workspace data, host state, sidecars, caches, vaults, and external sources.

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Review secret handling, brokered execution, redaction, vault boundaries, host approval, and public hygiene.

日本語の概要は準備中です。原文の説明を表示しています。

React bindings for TanStack Router: RouterProvider, useRouter, useRouterState, useMatch, useMatches, useLocation, useSearch, useParams, useNavigate, useLoaderData, useLoaderDeps, useRouteContext, useBlocker, useCanGoBack, Link, Navigate, Outlet, CatchBoundary, ErrorComponent. React-specific patterns for hooks, providers, SSR hydration, and createLink with forwardRef.

日本語の概要は準備中です。原文の説明を表示しています。