「gc」の検索結果

Stores and operates on sparse expression matrices for single-cell and large bulk RNA-seq, covering dgCMatrix/dgRMatrix/dgTMatrix when-each-is-fast, the dgCMatrix (CSC, R) <-> CSR (Python) implicit transpose, AnnData (cells-rows) <-> SingleCellExperiment (cells-cols) orientation flip, HDF5/h5ad vs Zarr cloud-native shift, HDF5SummarizedExperiment + DelayedArray for out-of-memory bulk, scanpy backed mode for large h5ad, the ~10-15% density crossover where dense beats sparse, 10X format proliferation (MTX vs CellRanger H5 vs h5ad), the dense-conversion memory blow-up, and Dask + Zarr for consortium-scale matrices. Use when choosing sparse format, working with single-cell-sized matrices, importing/exporting 10X, debugging R/Python interop transposes, processing matrices too large for RAM, or building cloud-native pipelines.

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Build weighted gene co-expression networks to identify modules of co-regulated genes, relate them to phenotypes, and find hub genes using WGCNA, hdWGCNA, MEGENA, CEMiTool, and Gaussian graphical models. Covers signed-network choice, soft-threshold selection, module preservation, and the marginal-vs-partial-correlation distinction. Use when finding co-expression modules, identifying hub genes, relating gene networks to clinical or experimental traits, or building single-cell co-expression networks. For directed TF-target inference see scenic-regulons and grn-inference; for condition rewiring see differential-networks.

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Normalizes and transforms RNA-seq count matrices for DE, visualization, clustering, and ML. Covers between-sample (TMM, TMMwsp, RLE/median-of-ratios, upper quartile), within-sample (TPM, FPKM/RPKM), variance-stabilizing (VST, rlog, log-CPM), GC-content correction (cqn, EDASeq), and single-cell (scran deconvolution, scanpy normalize_total). Encodes the composition-bias rationale, the "most genes not DE" assumption and its catastrophic failure modes (MYC amplification, apoptosis, viral host shutoff, prokaryotic stress), the "lengthScaledTPM is not TPM" naming trap, the "TPM is not for DE" rule, the blind=TRUE vs FALSE decision, ERCC spike-in normalization (SBN), and the single-cell zero-inflation breakdown of TMM/RLE. Use when choosing or applying normalization, debugging shifted-MA-plot diagnostics, handling zero-heavy single-cell data, or correcting GC bias.

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Call copy number variants with the GATK best-practices workflows — the somatic CNV pipeline (CollectReadCounts, DenoiseReadCounts with tangent normalization, ModelSegments, CallCopyRatioSegments) and the germline GATK-gCNV pipeline (DetermineGermlineContigPloidy, GermlineCNVCaller cohort/case mode, PostprocessGermlineCNVCalls). Covers panel-of-normals construction, AnnotateIntervals/FilterIntervals, allelic-count integration, and QS-based filtering. Use when integrating CNV calling into a GATK variant pipeline, calling rare germline CNVs from an exome cohort, deciding between the somatic and germline GATK workflows, or diagnosing why tangent normalization removed a real event or why gCNV output has low precision.

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Detect horizontal gene transfer (HGT / LGT) using compositional methods (GC%, codon usage, tetranucleotide z-scores via SIGI-HMM, AlienHunter, IslandViewer 4, IslandPath-DIMOB), phylogenetic-incongruence methods (AvP, HGTphyloDetect, ALE / GeneRax / AleRax reconciliation, RANGER-DTL), and BLAST-distribution methods (HGTector v2, DarkHorse, Alien Index). Use when screening prokaryote genomes for genomic islands and HGT events, distinguishing HGT from incomplete lineage sorting / differential gene loss / hybridization, mapping donor lineages via phylogenetic placement, separating eukaryotic HGT from contamination, ruling out gBGC as a false signal, or quantifying DTL rates with ALE/GeneRax on bacterial trees.

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Locate CCSPlayerInventory::m_pSOCache in CS2 server.dll / libserver.so via IDA Pro MCP and emit a fresh, minimal-unique signature or offset for the WeaponPaints gamedata entry "CCSPlayerInventory::m_pSOCache" (symbol CCSPlayerInventory_m_pSOCache). This is a STRUCT MEMBER OFFSET (schema netvar). Resolve the CCSPlayerInventory class layout via the schema system; m_pSOCache is the CGCClientSharedObjectCache pointer member. Cross-check: CCSPlayerInventory methods load this pointer and pass it to CGCClientSharedObjectCache methods (the GetItemInLoadout shortlist is a strong caller-side witness). Trigger: CCSPlayerInventory_m_pSOCache, CCSPlayerInventory::m_pSOCache

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开发运行在Android 11上的C++程序，仿照logcat功能，通过NDK Android Logger API从logd读取日志。

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AI 视频生成全流程：通过 6 个阶段（剧本→角色/场景设计→分镜→参考图→视频生成→后期剪辑）将用户想法转化为完整视频。支持临时工作台（单独调用 LLM、VLM、文生图、图生图、视频生成）。触发词：视频生成、AI视频、AIGC、创作视频、制作视频、AI画图。

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This skill details how to conduct cloud security audits using Center for Internet Security benchmarks for AWS, Azure, and GCP. It covers interpreting CIS Foundations Benchmark controls, running automated assessments with tools like Prowler and ScoutSuite, remediating failed controls, and maintaining continuous compliance monitoring against CIS v5 for AWS, v4 for Azure, and v4 for GCP.

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Detect abnormal access patterns in AWS S3, GCS, and Azure Blob Storage by analyzing CloudTrail Data Events, GCS audit logs, and Azure Storage Analytics. Identifies after-hours bulk downloads, access from new IP addresses, unusual API calls (GetObject spikes), and potential data exfiltration using statistical baselines and time-series anomaly detection.

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Comprehensive secrets extraction methodology targeting CI/CD environments across all major platforms. Covers environment variable extraction from build contexts, exploitation of vault and secrets-manager misconfigurations (HashiCorp Vault, AWS Secrets Manager, Azure Key Vault, GCP Secret Manager), runner and agent token abuse for lateral movement, OIDC federation attacks exploiting trust relationships between CI/CD providers and cloud platforms, build log leakage analysis for inadvertently exposed credentials, cache poisoning techniques for credential exfiltration, platform-specific credential store exploitation (GitHub Actions secrets, GitLab CI variables, Jenkins credential providers), service connection and service account abuse in Azure DevOps and GCP, and Docker registry credential theft from build environments. Maps to MITRE ATT&CK T1552 (Unsecured Credentials) and its sub-techniques. Each section provides enumeration procedures, extraction techniques, and post-exploitation pivoting guidance for usi...

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Hunting skill for cache poison vulnerabilities. Built from 10 public bug bounty reports including X-Forwarded-Host poisoning, X-HTTP-Method-Override / GCS cache, reflected→stored XSS via cache, classic Omer-Gil Web Cache Deception, Cloudflare Cache Deception Armor bypass, session-token cache deception, Akamai hop-by-hop smuggling → server-side edge poisoning, and Kettle's 2024 path-normalization WCD against Cloudflare/Fastly/GCP. Host/X-Forwarded-Host injection that reaches app logic (reset-link poisoning, routing SSRF, OAuth issuer) is owned by hunt-host-header; this skill owns the case where the poisoned response is CACHED and served to other users. Use when hunting cache poisoning, Web Cache Deception, CDN-fronted apps.

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Companion to the generic report-writing skill. Use when working specifically on Bugcrowd submissions where VRT mapping, OOS-clause rebuttals, or per-program target selection matter.

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Expert in LangGraph - the production-grade framework for building stateful, multi-actor AI applications. Covers graph construction, state management, cycles and branches, persistence with checkpointers, human-in-the-loop patterns, and the ReAct agent pattern. Used in production at LinkedIn, Uber, and 400+ companies. This is LangChain's recommended approach for building agents. Use when: langgraph, langchain agent, stateful agent, agent graph, react agent.

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Specialized skill for building production-ready serverless applications on GCP. Covers Cloud Run services (containerized), Cloud Run Functions (event-driven), cold start optimization, and event-driven architecture with Pub/Sub.

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Goのコード作成・レビュー・リファクタリングを、言語の慣習に沿って支援します。エラー処理、並行処理、パッケージ構成を整え、読みやすく保守しやすい実装を目指します。

• Goの慣習に沿ってコードをレビュー
• 既存コードのエラー処理を改善したいとき
• キャンセル可能な並行処理を設計

NVIDIA GPU上で大規模言語モデルの応答生成を高速化し、APIとして提供する設定を支援します。量子化や一括処理、複数GPUへの分散も扱います。

• 言語モデルをチャットAPIで提供したいとき
• 多数のプロンプトを一括処理したいとき
• 量子化でメモリ使用量を抑えたいとき

文章などを数値化して似た内容を探す検索をQdrantで実装。属性による絞り込みやAI回答用の資料検索から、大規模運用の設定・調整まで支援します。

• AI回答用の参考資料を検索したいとき
• カテゴリや日時で絞る類似検索
• リアルタイム推薦の実装

Reference for the Claude API / Anthropic SDK — model ids, pricing, params, streaming, tool use, MCP, agents, caching, token counting, model migration. TRIGGER — read BEFORE opening the target file; don't skip because it "looks like a one-liner" — whenever: the prompt names Claude/Anthropic in any form (Claude, Anthropic, Fable, Opus, Sonnet, Haiku, `anthropic`, `@anthropic-ai`, `claude-*`, `us.anthropic.*`, `[1m]`); the user asks about an LLM (pricing/model choice/limits/caching) — never answer from memory; OR the task is LLM-shaped with provider unstated (agent/MCP/tool-definition/multi-agent/RAG/LLM-judge/computer-use; generate/summarize/extract/classify/rewrite/converse over NL; debugging refusals/cutoffs/streaming/tool-calls/tokens). SKIP only when another provider is being worked on (overrides all triggers): OpenAI/GPT/Gemini/Llama/Mistral/Cohere/Ollama named in the query; OR `grep -rE 'openai|langchain_openai|google.generativeai|genai|mistralai|cohere|ollama'` over the project hits (run this grep FIRST if no provider named — don't Read the file).

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Train RuView models — camera-free WiFlow pose (10 sensor signals, no labels), camera-supervised pose (MediaPipe + ESP32 CSI → 92.9% PCK@20, ADR-079), RuVector contrastive embeddings (AETHER, ADR-024), domain generalization (MERIDIAN, ADR-027), local SNN environment adaptation, plus GPU training on GCloud and Hugging Face publishing. Use when building, fine-tuning, evaluating, or shipping a model.

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Android device and emulator control from inside Orca over adb, with the live device view in Orca's emulator pane. Use when driving an adb-connected emulator or phone on Windows, Linux, or macOS: booting AVDs, taps, swipes, typing, hardware buttons, rotation, app install and launch, runtime permissions, the accessibility tree, and logcat. For an iOS simulator use the iOS emulator skill; build the APK with Gradle first.

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Debug LangChain and LangGraph agents by fetching execution traces from LangSmith Studio. Use when debugging agent behavior, investigating errors, analyzing tool calls, checking memory operations, or examining agent performance. Automatically fetches recent traces and analyzes execution patterns. Requires langsmith-fetch CLI installed.

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Reference for the Claude API / Anthropic SDK — model ids, pricing, params, streaming, tool use, MCP, agents, caching, token counting, model migration. TRIGGER — read BEFORE opening the target file; don't skip because it "looks like a one-liner" — whenever: the prompt names Claude/Anthropic in any form (Claude, Anthropic, Fable, Opus, Sonnet, Haiku, `anthropic`, `@anthropic-ai`, `claude-*`, `us.anthropic.*`, `[1m]`); the user asks about an LLM (pricing/model choice/limits/caching) — never answer from memory; OR the task is LLM-shaped with provider unstated (agent/MCP/tool-definition/multi-agent/RAG/LLM-judge/computer-use; generate/summarize/extract/classify/rewrite/converse over NL; debugging refusals/cutoffs/streaming/tool-calls/tokens). SKIP only when another provider is being worked on (overrides all triggers): OpenAI/GPT/Gemini/Llama/Mistral/Cohere/Ollama named in the query; OR `grep -rE 'openai|langchain_openai|google.generativeai|genai|mistralai|cohere|ollama'` over the project hits (run this grep FIRST if no provider named — don't Read the file).

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When the user wants to generate, iterate, or scale ad creative — headlines, descriptions, primary text, or full ad variations — for any paid advertising platform. Also use when the user mentions 'ad copy variations,' 'ad creative,' 'generate headlines,' 'RSA headlines,' 'bulk ad copy,' 'creative testing,' 'write me some ads,' 'Facebook ad copy,' 'Google ad headlines,' 'LinkedIn ad text,' 'static ads,' 'ad templates,' 'iMessage ad,' 'ChatGPT ad,' 'creative strategy,' 'creative roadmap,' 'creative retro,' 'hook writing,' 'creative review page,' 'motion video ad,' 'faceless video ad,' 'UGC ad,' 'greenscreen ad,' 'TikTok/Reels ad format,' 'Meta ad format tier list,' or 'creative format taxonomy.' Use it to produce or iterate ad copy at scale. Copy avoids AI tells like 'it's not X, it's Y' reveals. For campaign strategy and targeting, see ads. For landing page copy, see copywriting. Test hypotheses must be falsifiable, naming the metric, the comparison, and the expected direction.

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