556 件 ・ 関連度順
概要と使いどころ
Deep Codex-native Amazon FBA product validation using LaunchFast MCP and the LegacyX criteria. Use when the user wants a serious viability review for a keyword, niche, or adjacent niche expansion.
日本語の概要は準備中です。原文の説明を表示しています。
Create faithful studio, lifestyle, and on-model product photography through the GooseWorks Product Photos workflow, then approve selected results for reuse in future creative work.
日本語の概要は準備中です。原文の説明を表示しています。
Nominates and assesses CRISPR off-target sites genome-wide. Enumerates candidate sites by mismatch and bulge tolerance with Cas-OFFinder/CRISPRitz, ranks them with the published CFD score (SpCas9-only, relative ranker) or MIT/CRISTA/energy models, runs variant-aware screening against gnomAD/individual genomes (CRISPRme), and frames the empirical genome-wide discovery assays (GUIDE-seq, CIRCLE-seq, CHANGE-seq, DISCOVER-seq, Digenome-seq) and high-fidelity nuclease choice (HiFi Cas9, Sniper-Cas9, eSpCas9, SpCas9-HF1). Use when assessing guide RNA specificity, choosing among candidate guides, screening a therapeutic guide against population variation, or planning empirical off-target validation. Distinguishes predicted vs detected vs validated. On-target activity scoring and deaminase (Cas-independent) base/prime-editor off-targets are separate skills.
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Designs and ranks guide RNAs (sgRNAs) for CRISPR-Cas9/Cas12a gene knockout by scanning a target for PAM sites (NGG SpCas9, NNGRRT SaCas9, TTTV Cas12a, NG SpCas9-NG, near-PAMless SpRY), enumerating candidate spacers, applying hard filters (Pol-III TTTT terminator, 5' G, GC), ranking on-target activity with the context-appropriate model (Rule Set 2/Azimuth for U6/lentiviral, CRISPRscan for T7/embryo, DeepHF for high-fidelity variants, DeepCpf1 for Cas12a), and predicting the indel/frameshift outcome (Bae out-of-frame score, inDelphi, FORECasT, Lindel). Use when selecting sgRNAs to knock out a gene, choosing a nuclease/PAM for a constrained locus, picking which exon to target, or shortlisting guides before an off-target check. Off-target specificity, base/prime editing, and HDR donors are separate skills.
日本語の概要は準備中です。原文の説明を表示しています。
Maps between gene identifier systems (Ensembl, Entrez, HGNC symbol, UniProt, RefSeq, MANE) using AnnotationDbi, biomaRt, mygene, pyensembl, and Ensembl REST. Encodes Ensembl version stripping with GENCODE _PAR_Y preservation, the Ziemann 2016 Excel autocorrect debacle and Bruford 2020 HGNC renames (SEPT*->SEPTIN*, MARCH*->MARCHF*, MARC*->MTARC*, DEC1->DELEC1), OCT4/POU5F1 alias resolution, biomaRt archive endpoints for release pinning, the `filters` (plural) gotcha, MANE Select for clinical reporting, cross-species orthology via Ensembl Compara / OMA / OrthoDB, and tx2gene construction for tximport. Use when converting gene IDs across systems, handling renamed symbols, building tx2gene, pinning to a specific Ensembl release for reproducibility, or mapping cross-species orthologs.
日本語の概要は準備中です。原文の説明を表示しています。
Calculates molecular fingerprints (ECFP/Morgan, FCFP, MACCS, RDKit, AtomPair, TopologicalTorsion, Avalon, MAP4, MHFP6) and physicochemical descriptors (Lipinski, QED, TPSA, Crippen LogP, 3D shape) with explicit choice tables, bit vs count semantics, and partial-charge model selection. Use when featurizing molecules for similarity, QSAR, virtual screening, or ML, or selecting the correct fingerprint for a chemotype-aware task.
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Performs retrosynthetic planning using AiZynthFinder (template-based MCTS), maintained or version-pinned template-free models, ASKCOS, and emerging RetroSynFormer with explicit handling of route scoring, configurable MCTS rewards, building-block availability, and forward-prediction checks. Use when assessing synthetic feasibility of generated or selected molecules, planning multi-step syntheses, building synthesis-aware design pipelines, or screening libraries for retro-route feasibility.
日本語の概要は準備中です。原文の説明を表示しています。
Performs molecular similarity searching using Tanimoto, Tversky, Dice, and cosine coefficients on bit/count fingerprints with explicit choice rules for symmetric vs asymmetric measures, scaffold-hopping vs lead-optimization regimes, activity-cliff diagnosis, and large-library nearest-neighbor methods (BulkTanimoto, MHFP6 LSH forest, USRCAT). Use when ranking compounds by structural resemblance to a query, clustering libraries, finding analogs, or diagnosing activity cliffs.
日本語の概要は準備中です。原文の説明を表示しています。
Use for new frontend applications, dashboards, games, creative websites, hero sections, and visually driven UI from scratch, or when the user explicitly asks for a redesign/restyle/modernization. Builds from clean, airy, high-taste, readable image-generated concept design with section-specific references, faithful implementation, and browser testing.
日本語の概要は準備中です。原文の説明を表示しています。
Integrate antennas into RF systems using MATLAB Antenna Toolbox and RF Toolbox. Covers impedance matching network design (L/Pi/Tee topologies, evaluation parameters, Richards transformation), measured antenna creation (E-field, directivity-only, EmbeddedE, ffsReader import), RF propagation and site planning (txsite/rxsite, coverage, SINR, ray tracing, link budget), and SAR estimation (birdcage+Phantom, conformalArray+Custom3D, direct EHfields). Use when the user wants to match an antenna, create a measuredAntenna, compute coverage or signal strength, perform ray tracing, or estimate SAR.
日本語の概要は準備中です。原文の説明を表示しています。
Review a business plan from the perspective of the solo founder who has to actually execute it. Asks the brutal operational questions: Can I build this with my time budget? Can I keep it running? Will my cashflow survive? Outputs a verdict — SHIPPABLE NOW / SHIPPABLE WITH DESCOPE / NEEDS HIRE / WRONG STACK. Use when a plan looks great on paper and you want to know whether a solo operator can actually execute it. Triggered by: 'operator review', 'can I actually do this solo', 'execution reality check', '操盘视角', '我能不能干得动'.
日本語の概要は準備中です。原文の説明を表示しています。
Faithfully append a human modeler's choice and rationale to one canonical per-subquestion JSONL decision ledger. Use after a choice card is answered or when migrating legacy decision artifacts; never originate or improve the decision.
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Use when building gameplay systems in Godot 4.7: enemy AI that patrols, chases and attacks, state machines, behavior trees (LimboAI), NavigationAgent3D pathfinding and avoidance for 100 to 1000 enemies, 'agents stack up' or 'path is empty', hitbox and hurtbox combat, fast bullets going through walls, save and load, inventory, quests, dialogue (Dialogue Manager), input remapping, procedural dungeons, or measuring agent counts and frame time headless.
日本語の概要は準備中です。原文の説明を表示しています。
Use when producing a video ad with Scenario from a product shot or brand assets: a mobile 9:16 or landscape 16:9 commercial, a TikTok, Reels, Shorts, YouTube, or CTV spot, or campaign creative needing a creative brief, storyboard, cinematic camera work, brand-faithful product footage, music and voiceover, captions, ad variants, budget planning, or platform delivery specs. Keywords: video ad, commercial, product video, advert, hook, CTA, end card, campaign, ad creative.
日本語の概要は準備中です。原文の説明を表示しています。
Audit code for correctness and rigor — logic errors, silent error swallowing, wishful thinking, and unjustified fallbacks. This is not a style review; it's a logic review. Use when you want a focused correctness audit separate from the full code-police pass.
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Fine-tunes LLMs and trains custom models using LoRA/QLoRA adapters, JSONL training datasets, hyperparameter configuration, RLHF, DPO, and model quantization.
日本語の概要は準備中です。原文の説明を表示しています。
Use when the user has a RAG (Retrieval-Augmented Generation) system and wants to evaluate its quality — separating retrieval issues from generation issues. Also use when the user mentions RAG evaluation, faithfulness checking, hallucination detection in RAG, retrieval quality, chunking optimization, or "is my RAG pipeline working." Outputs a diagnostic matrix that pinpoints whether problems are in retrieval or generation.
日本語の概要は準備中です。原文の説明を表示しています。
A retro Bayer-dithered noise wave — pixelated, quantized, faithful GPU shader. A marketing-grade hero backdrop. One per view; scrim behind text. Renders a static frame under prefers-reduced-motion.
日本語の概要は準備中です。原文の説明を表示しています。
Evaluates LLMs across 60+ academic benchmarks (MMLU, HumanEval, GSM8K, TruthfulQA, HellaSwag). Use when benchmarking model quality, comparing models, reporting academic results, or tracking training progress. Industry standard used by EleutherAI, HuggingFace, and major labs. Supports HuggingFace, vLLM, APIs.
日本語の概要は準備中です。原文の説明を表示しています。
Expert blueprint for tower defense games (Bloons TD, Kingdom Rush, Fieldrunners) covering wave management, tower targeting logic, path algorithms, economy balance, and mazing mechanics. Use when building TD, lane defense, or tower placement strategy games. Keywords tower defense, wave spawner, pathfinding, targeting priority, mazing, NavigationServer baking.
日本語の概要は準備中です。原文の説明を表示しています。
Bevy ECS skill for navigation. Keywords: Bevy, navigation, pathfinding, ECS.
日本語の概要は準備中です。原文の説明を表示しています。
Provides R wrappers of several on-target and off-target scoring methods for CRISPR guide RNAs (gRNAs). The following nucleases are supported: SpCas9, AsCas12a, enAsCas12a, and RfxCas13d (CasRx). The available on-target cutting efficiency scoring methods are RuleSet1, Azimuth, DeepHF, DeepCpf1, enPAM+GB, and CRISPRscan. Both the CFD and MIT scoring methods are available for off-target specificity prediction. The package also provides a Lindel-derived score to predict the probability of a gRNA to
日本語の概要は準備中です。原文の説明を表示しています。
Expert knowledge for Microsoft Foundry Local (aka Azure AI Foundry Local) development including best practices, decision making, configuration, and integrations & coding patterns. Use when compiling HF models with Olive, using Foundry Local CLI, embeddings/chat/audio APIs, or OpenAI-style integrations, and other Microsoft Foundry Local related development tasks. Not for Microsoft Foundry (use microsoft-foundry), Microsoft Foundry Classic (use microsoft-foundry-classic), Azure Local (use azure-local), Azure Content Understanding in Foundry Tools (use azure-content-understanding).
日本語の概要は準備中です。原文の説明を表示しています。
Use when the user mentions the Higgsfield CLI (binaries `higgsfield` / `higgs` / `hf`, `higgsfield auth login`, `higgsfield generate create`, `higgsfield workflow`, the `@higgsfield/cli` npm package), the Higgsfield MCP custom connector (`mcp.higgsfield.ai/mcp`) or its bundled workflows (`get_workflow_instructions` — character-sheet, thumbnail-generation, ugc-* videos, faceless-video, narrator, subtitles, product-photoshoot, brand-asset-creation, ad-multiplier, video-editing / Higgsedit, website-builder-flow), Higgsfield's bundled skills repo (`higgsfield-ai/skills` — `higgsfield-generate`, `higgsfield-soul-id`, `higgsfield-product-photoshoot`, `higgsfield-brandkit`, `higgsfield-marketplace-cards`, `higgsfield-websites`, `higgsfield-video-explainer`, `higgsfield-youtube-thumbnail`, invoked as `/higgsfield:generate` etc.), or asks how this skill coexists with those tools (`do I need both`, `how does this work with the CLI/MCP/skills`, `should Higgsfield's workflow do this or you`).
日本語の概要は準備中です。原文の説明を表示しています。