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概要と使いどころ
Process-based discrete-event simulation. Model queues, shared resources, timed events: manufacturing, service ops, network traffic, logistics. Processes are Python generators yielding events. Resources: capacity-limited (Resource/Priority/Preemptive), bulk (Container), objects (Store, FilterStore). For continuous use SciPy ODEs; for agent-based use Mesa.
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LLM-driven hypothesis generation/testing on tabular data. Three methods: HypoGeniC (data-driven), HypoRefine (literature+data), Union. Iterative refinement, Redis caching, multi-hypothesis inference. Manual: hypothesis-generation; ideation: scientific-brainstorming.
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Python framework for single- and multi-objective optimization with evolutionary algorithms. Define vectorized objectives and constraints; solve with NSGA-II, NSGA-III, MOEA/D, GAs, or differential evolution. Analyze Pareto fronts, visualize trade-offs, customize operators and callbacks. For engineering design, hyperparameter search, and conflicting objectives. Alternatives: scipy.optimize (single-objective, gradient), platypus, jMetalPy (Java).
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Universal QA checklist for generated scientific plots: overlapping labels, clipped text, missing axes/legends, overcrowded data, and cross-journal resolution/format guidance.
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Symbolic math in Python: exact algebra, calculus (derivatives, integrals, limits), equation solving, symbolic matrices, ODEs, code gen (lambdify, C/Fortran). Use for exact symbolic results. For numerical use numpy/scipy; for stats use statsmodels.
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Python toolkit for neurophysiological signal processing: ECG (HR, HRV, R-peaks), EEG (complexity, PSD), EMG (activation onset), EDA/GSR (SCR decomposition), PPG, and RSP. Includes synthetic signal simulation. Alternatives: BioSPPy (less maintained), MNE (EEG/MEG specialist), heartpy (ECG only), scipy.signal (raw DSP).
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Methodology for exploratory data analysis on scientific files. Decision frameworks by data type (tabular, sequence, image, spectral, structural, omics), quality assessment, report generation, format detection across 200+ formats. Use when given a data file for initial exploration or to pick an analysis before a pipeline.
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Interactive scientific visualization with Plotly. Two APIs: plotly.express (px) for one-liner DataFrame plots, plotly.graph_objects (go) for trace-level control. 40+ chart types with hover, zoom, pan, animation. Exports HTML or static PNG/SVG/PDF via kaleido. Use for volcano plots with gene hover, dose-response dashboards, expression heatmaps, 3D molecular views. Use seaborn for stats; matplotlib for publication figures.
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DL cell/nucleus segmentation for fluorescence and brightfield microscopy. Pre-trained models (cyto3, nuclei, tissuenet) and a generalist flow-based algorithm segment cells without retraining. Outputs label masks for morphology and tracking. Use scikit-image watershed for rule-based; Cellpose when DL generalization across staining is needed.
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Python bridge to ImageJ2/Fiji for macros, plugins (Bio-Formats, TrackMate, Analyze Particles), NumPy↔ImagePlus/ImgLib2 exchange, and ImageJ Ops. Automates Fiji headlessly from Python. Use scikit-image for pure Python without Fiji plugins; napari for visualization.
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Python statistical modeling: regression (OLS, WLS, GLM), discrete (Logit, Poisson, NegBin), time series (ARIMA, SARIMAX, VAR), with rigorous inference, diagnostics, and hypothesis tests. Use scikit-learn for ML; statistical-analysis for test choice.
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Python library for biology: sequence manipulation (DNA/RNA/protein), pairwise/multiple alignment, phylogenetic trees (NJ, UPGMA), diversity (Shannon, Faith PD, Bray-Curtis, UniFrac), ordination (PCoA, CCA, RDA), stats (PERMANOVA, ANOSIM, Mantel), file I/O (FASTA, FASTQ, Newick, BIOM). Use for microbiome, community ecology, or phylogenetics.
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Use when creating new skills, editing existing skills, or verifying skills work before deployment
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Use when starting any conversation - establishes how to find and use skills, requiring Skill tool invocation before ANY response including clarifying questions
日本語の概要は準備中です。原文の説明を表示しています。
Verifies math-heavy code for algorithmic correctness and numerical stability. Use when reviewing scientific algorithms, ML models, or numerical code.
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Use when a skill fails for a missing tool or the environment needs checking. Diagnoses Python, R, Node, Claude Code, Git, Zotero and configured MCP servers and prints a pass/fail table with links to the setup docs. Read-only; installs nothing.
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Use when the user describes a research goal without naming a skill, or the task spans several skills. Classifies the request, plans the order and routes to the right medsci-skills skill(s) instead of producing their output itself.
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Use DGL-LifeSci and dgllife for molecular graph learning, molecule featurization, datasets, property prediction, reaction prediction, binding affinity, model-zoo/pretrained models, and molecular generation workflows.
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Operate the ai-data-science-team package for AI-assisted data loading, EDA, pandas transformations, SQL analysis, H2O/MLflow modeling, multi-agent teams, and Streamlit app workflows.
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Shared discipline for every hunt-* skill: scope and authorization gating, the two-account rule, the confirmation gate that separates a real finding from a false positive, enumeration limits, stop conditions, marker discipline, wiki-first query and self-heal, FIND output, Deadends, and wiki distillation. ALWAYS LOADED alongside any hunt skill. Also trigger directly on "is this in scope", "is this a real bug", "how do I confirm this", "should I keep going", "how many IDs should I test", "what severity", "how do I report this", "I got someone else's data". Every hunt-* skill assumes this file; without it they run without their safety and quality layer.
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This skill should be used when the user asks about "mystery", "fair play", "clue", "red herring", "romance beats", "HEA", "thriller", "ticking clock", "horror", "dread", "MG", "YA", "middle grade", "young adult", "science fiction", "sci-fi", "fantasy", "quest", "chosen one", "historical fiction", "period voice", "anachronism", "comedy", "humour", "humor", "romcom", "farce", "satire", "running gag", "serial", "episodic", "web serial", "genre conventions", or wants genre-specific structural craft for a story project. NOT for a clue check as a revision pass (use revision-continuity).
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Guide for managing consent for scientific research under GDPR Article 89 and Recital 33 broad consent provisions. Covers ethical review board coordination, purpose evolution management, appropriate safeguards including pseudonymization, and the interplay between consent and other lawful bases for research processing.
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Applies the reasoning style of Geoffrey Hinton, deep learning pioneer and 2018 Turing Award winner. Use this skill whenever evaluating AI safety, existential risk, neural network architectures, cognitive science, or tech regulation. Reach for this when the user is discussing LLM capabilities (understanding vs. autocomplete), the biological vs. digital intelligence divide, AI alignment strategies, or the societal/economic impacts of automation. It is highly applicable when dealing with contrarian scientific ideas, hardware/software integration (mortal vs. immortal computing), or global cooperation on technological threats. Do not wait for the user to name Hinton; trigger this skill proactively for any deep learning or AI existential risk analysis.
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Applies the reasoning style of Kaiming He, computer vision pioneer and creator of ResNet. Use this skill whenever you are designing deep learning architectures, debugging neural network optimization, formulating generative AI problems, or bridging AI with other scientific domains. Trigger this skill for discussions on network depth, weight initialization, residual learning, flow matching, or when reframing discriminative tasks as conditional generation. It emphasizes simplicity in complex visual problems, end-to-end optimization, and viewing AI as a universal language for science.
日本語の概要は準備中です。原文の説明を表示しています。