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Performs differential expression on bulk RNA-seq count data with edgeR's negative-binomial GLM and quasi-likelihood F-test framework. Covers DGEList construction, filterByExpr, TMM/TMMwsp normalization, robust dispersion estimation, glmQLFit/glmQLFTest, TREAT for magnitude-bounded hypotheses, contrasts via no-intercept designs, voom and voomWithQualityWeights for heterogeneous samples, and the edgeR v4 bias-corrected APL changes. Use when running bulk DE with edgeR, choosing edgeR over DESeq2 (small n, transcript DE via catchSalmon, large samples), needing TREAT for a fold-change-threshold hypothesis, troubleshooting v3-to-v4 reproducibility, building paired or interaction designs, or handling library-quality heterogeneity.

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Generate 3GPP-compliant 5G NR downlink and uplink baseband waveforms. Use to create NR signals, test model (TM) waveforms, fixed reference channels (FRC), test and measurement (T&M) signals, or test vectors for conformance testing. Covers configuring data, control, and broadcast channels and signals: PDSCH, PUSCH, PDCCH, PUCCH, SRS, SSBurst, CSI-RS, DM-RS, PT-RS, CORESET, and BWP parameters including bandwidth, subcarrier spacing (SCS), modulation (QPSK, QAM), numerology, FR1, FR2, TDD, FDD, and multi-bandwidth-part setups. Use for signal generation, RF instrument playback, or IQ baseband synthesis. Requires 5G Toolbox.

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Verify claims, quotations, citations and references against live primary sources, and produce a reproducible audit record instead of an assertion. Use when asked to: check whether a quotation, verse, statistic, date, attribution or citation is accurate; verify references before publishing a report, thesis, article, slide deck or legal filing; confirm a text against an authoritative database; cross-check a claim across independent sources; build a citation register or verification appendix; find out whether two datasets agree; detect a misattributed or fabricated quotation; or audit a document's existing citations. Source-agnostic by design, with working providers for REST/JSON APIs, scraped HTML, bulk corpora, bibliographic catalogues (OpenLibrary), DOI resolution (Crossref) and reference works (Wikipedia) -- including scriptural tiers (Qur'an.com, sunnah.com and an independent hadith corpus) with full diacritic handling for Arabic, Hebrew, Greek and any script with optional marks. Covers content-addressed matching when sources disagree on numbering, graded match verdicts, byte-level integrity checks, published-string verification, and a catalogue of silent failure modes (identifier divergence, mojibake, scraper blocking, false-positive keyword rules, missing glyphs, unreliable PDF text layers).

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Apply step-by-step analysis for complex problems with revision capability. Use for multi-step reasoning, hypothesis verification, adaptive planning, problem decomposition, course correction.

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Assess a field lesson for reuse or product feedback without exposing customer context. Use for recurring deployment lessons; distinguish a hypothesis from a validated pattern.

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Plan and run usability tests on existing or prototype designs including test design, task scripts, moderation, observation, and findings synthesis. Use this skill whenever the user wants to test usability, run a moderated test, run an unmoderated test, validate a design, find usability issues, or improve task completion. Triggers on usability test, usability testing, moderated test, unmoderated test, task script, think aloud, prototype testing, user testing, design validation, task completion. Also triggers when the user has built something and wants to know if real users can use it before shipping.

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Produce honest product reviews and buying guides without fabricated first-hand experience, using disclosed evidence tiers: verified specs, owner-experience synthesis at scale, expert triangulation, and hands-on only when true. Use this skill whenever the user wants to write product reviews or buying guides without hands-on access, set up a review methodology, add evidence disclosure to review content, align reviews with Google's reviews system or FTC affiliate disclosure expectations, or decide when Review and Product schema are honest to use. Triggers on product review, buying guide, best-of list, review methodology, evidence basis, hands-on testing, we tested, affiliate review site, review disclosure, methodology block, original research, reviews system. Also triggers when review content claims testing that did not happen, or when an affiliate site needs a trust mechanism that survives scrutiny.

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How to read experiment results without fooling yourself. Confidence intervals, p-values, multiple testing, sequential testing, CUPED, heterogeneous treatment effects, ratio metrics, network effects, dashboard reconciliation, and the interpretation failures that produce confidently wrong shipping decisions. Use this skill whenever the user is reading a finished experiment result panel and about to make a ship, kill, or iterate decision, or when an experiment number does not match the dashboard number. Triggers on read experiment results, result panel, ship or kill decision, p-value, confidence interval, statistical significance, multiple testing, peeking, sequential testing, CUPED, variance reduction, heterogeneous treatment effects, ratio metric, network effects, inconclusive test, experiment versus dashboard mismatch. Use `experiment-design` instead when the test has not run yet and the question is hypothesis, sample size, duration, or what to test.

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Systematic literature review with search, screening, and synthesis

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Hypothesis generation from scientific literature and data patterns

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Systematic root-cause debugging. Iron Law: no fixes without root cause investigation first. Four phases: Root Cause Investigation, Pattern Analysis (6 known patterns), Hypothesis Testing (3-strike rule), Implementation. Structured debug report output.

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Parses error messages, traces execution flow through stack traces, correlates log entries, and applies systematic hypothesis-driven methodology to isolate and resolve bugs.

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Continuous product discovery research operations — picking the method that fits the question, recruiting and screening participants, building interview guides, and scoring evidence into insights. Use when planning or running discovery.

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UX research and design toolkit covering persona generation, journey mapping, usability testing, and research synthesis. Use for user research, persona creation, journey mapping, or design validation.

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Product manager toolkit covering RICE prioritization, customer interview analysis, PRDs, and discovery frameworks. Use for feature prioritization, user research synthesis, requirement documentation, or product strategy.

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Synthesize raw user research (interviews, surveys, tickets) into themed findings and decision-ready briefs. Use when synthesizing user interviews, building a findings brief, or communicating research to stakeholders.

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Design and run statistically rigorous A/B tests and experiments. Use when planning experiments, calculating sample sizes, designing test variants, selecting metrics, analyzing results, or when someone says "let's test that."

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Applied statistics for business and product questions — test selection, assumption checks, power planning, effect sizes with intervals, multiplicity correction. Use when interpreting an experiment, sizing a study, or vetting a claim.

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Chaos engineering: hypothesis-driven fault injection to surface weakness before users do. Use when designing a chaos experiment, planning a gameday, choosing what to inject, computing blast radius, or building a chaos maturity model.

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Data analysis across SQL, visualization, statistics, and reporting. Use when writing SQL queries, building dashboards, performing cohort or funnel analysis, running hypothesis tests, or presenting data-driven recommendations.

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Run fable-mode execution discipline on Claude Haiku. Routes the task to the @fable-worker-haiku agent, whose definition carries the staged loop with tightened verification (no bare "unverified" allowed) and an escalate-don't-improvise rule. Trigger when the user explicitly asks for thorough/systematic handling run cheaply or fast ("fable on haiku", "deep work mode but cheap", "stage this on haiku"). For bulk mechanical work. Do NOT use for tasks needing synthesis — benchmark note: at n=1 the skill's effect on Haiku swung both directions (+25 / −17); route quality-critical work to fable-sonnet instead.

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Generate text, images, video, speech, and music via the MiniMax AI platform. Covers text generation (MiniMax-M3 model), image generation (image-01), video generation (Hailuo-2.3), speech synthesis (speech-2.8-hd, 300+ voices), music generation (music-2.6 with lyrics, cover, and instrumental), and web search. Use when the user needs to create AI-generated multimedia content, produce narrated audio from text, compose music, or search the web through MiniMax AI services.

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Panel health assessment, firm exit management, coverage gap analysis, and panel refresh brief for in-house legal ops teams. Produce an annual Panel Health Report synthesising scorecard data, billing compliance, and step-out patterns into per-firm recommendations — Retain, Watch, Improvement Plan, or Exit Review. Produce a firm exit pack: formal exit notice with active matter transition plan, plus an internal exit record. Identify practice area, geographic, or tier gaps and produce a structured Coverage Gap Report with remediation options. Produce a Panel Refresh Brief as a scoped input to the RFP process. Trigger on: 'review our panel', 'annual panel review', 'is our panel working', 'which firms should we exit', 'write the exit notice', 'coverage gap', 'we don't have anyone for restructuring', 'refresh the panel', 'panel rationalisation', 'too many firms', 'step-out problem', 'do we have the right firms'.

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Structure a decision or design challenge through multiple perspectives before committing to action. Use as a synthesis step after scoping, mapping, and dilemma navigation when a group needs a wiser next step.

日本語の概要は準備中です。原文の説明を表示しています。