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概要と使いどころ
Build Sankey, alluvial, river, and CONSORT-style flow diagrams to visualize cohort transitions, cell-state changes, or pipeline filtering using ggalluvial, networkD3, plotly, and consort. Use when showing how entities move between categories across timepoints (cell states, drug response classes, patient flow through a trial) or filtering pipelines (variants filtered through QC stages).
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Estimate divergence times using molecular clock models with BEAST2, MCMCTree, and TreePL. Use when dating speciation events, calibrating phylogenies with fossils, choosing between strict and relaxed clock models, or estimating evolutionary rates across lineages.
日本語の概要は準備中です。原文の説明を表示しています。
Detects circadian and ultradian rhythms in time-series omics data using CosinorPy cosinor models, MetaCycle (JTK_CYCLE, ARSER), and RAIN non-parametric tests. Fits cosine models to estimate phase and amplitude, tests rhythmicity significance at pre-specified periods. Use when testing for 24-hour or other known-period oscillations in circadian, feeding-fasting, or light-dark cycle experiments. Not for unknown-period discovery (see temporal-genomics/periodicity-detection).
日本語の概要は準備中です。原文の説明を表示しています。
Workflow for pseudotime, lineage branching, and state-transition analysis in single-cell data.
日本語の概要は準備中です。原文の説明を表示しています。
Boltz-1 / Boltz-2 structure prediction for proteins, complexes, and ligand-aware validation. Use this skill when: (1) Predicting protein complex structures, (2) Validating designed binders, (3) Need open-source alternative to AF2, (4) Predicting protein-ligand complexes, (5) Using local GPU resources. For QC thresholds, use protein-design-qc. For AlphaFold2 prediction, use alphafold2-multimer. For Chai prediction, use chai1-structure-prediction.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end guidance for protein design pipelines. Use this skill when: (1) Starting a new protein design project, (2) Need step-by-step workflow guidance, (3) Understanding the full design pipeline, (4) Planning compute resources and timelines, (5) Integrating multiple design tools. For tool selection, use binder-design. For QC thresholds, use protein-qc.
日本語の概要は準備中です。原文の説明を表示しています。
First-time setup for protein design tools. Use this skill when: (1) User is new and hasn't run any tools yet, (2) Commands fail with "file not found" or "modal: command not found", (3) Modal authentication errors occur, (4) User asks how to get started or set up the environment, (5) biomodals directory is missing or tools aren't working.
日本語の概要は準備中です。原文の説明を表示しています。
Binder design campaign planning, monitoring, and troubleshooting. Use this skill when: (1) Planning a complete binder design campaign, (2) Converting high-level goals into runnable pipelines, (3) Assessing campaign health and pass rates, (4) Diagnosing why designs are failing QC, (5) Estimating time, cost, and expected yields, (6) Selecting between design tools for a specific target. This skill orchestrates the other protein design tools. For individual tool parameters, use the specific tool skills.
日本語の概要は準備中です。原文の説明を表示しています。
Validate protein designs using AlphaFold2 structure prediction. Use this skill when: (1) Validating designed sequences fold correctly, (2) Predicting binder-target complex structures, (3) Calculating confidence metrics (pLDDT, pTM, ipTM), (4) Self-consistency validation of designs, (5) Multi-chain complex prediction with AlphaFold-Multimer. For faster single-chain prediction, use esm. For QC thresholds, use protein-qc.
日本語の概要は準備中です。原文の説明を表示しています。
End-to-end protein design pipeline guide across preparation, generation, validation, and filtering. Use this skill when: (1) Starting a new protein design project, (2) Need step-by-step workflow guidance, (3) Understanding the full design pipeline, (4) Planning compute resources and timelines, (5) Integrating multiple design tools. For tool selection, use binder-design-tool-selection. For QC thresholds, use protein-design-qc.
日本語の概要は準備中です。原文の説明を表示しています。
Chai-1 structure prediction for protein complexes and design validation. Use this skill when: (1) Predicting protein-protein complex structures, (2) Validating designed binders, (3) Predicting protein-ligand complexes, (4) Using the Chai API for high-throughput prediction, (5) Need an alternative to AlphaFold2. For QC thresholds, use protein-design-qc. For AlphaFold2 prediction, use alphafold2-multimer. For ESM-based analysis, use esm2-sequence-scoring.
日本語の概要は準備中です。原文の説明を表示しています。
Goal-oriented binder design campaign planning and health assessment. Use this skill when: (1) Planning a complete binder design campaign, (2) Converting high-level goals into runnable pipelines, (3) Assessing campaign health and pass rates, (4) Diagnosing why designs are failing QC, (5) Estimating time, cost, and expected yields, (6) Selecting between design tools for a specific target. This skill orchestrates the other protein design tools. For individual tool parameters, use the specific tool skills.
日本語の概要は準備中です。原文の説明を表示しています。
Research products across Amazon, Google Shopping, and Xiaohongshu to understand pricing, reviews, market positioning, and consumer sentiment. Covers competitive product analysis, pricing benchmarks, feature comparison, and customer satisfaction signals.
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Search videos, analyze channels, extract captions, read comments, and discover trends on YouTube through SandBase. Use when asked for YouTube research, video discovery, channel analysis, content strategy research, comment sentiment, or video transcript extraction.
日本語の概要は準備中です。原文の説明を表示しています。
Monitor conversations about any topic, brand, or keyword across Twitter, Reddit, Threads, Weibo, and community platforms simultaneously. Aggregates volume, sentiment, key voices, and emerging narratives across the global social web.
日本語の概要は準備中です。原文の説明を表示しています。
Search tweets, analyze trends, monitor users, and gather social intelligence from Twitter/X through SandBase. Use when asked for Twitter research, social listening, trend analysis, influencer monitoring, sentiment tracking, or competitor social intelligence.
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Research local markets by combining Google Maps reviews, Xiaohongshu local content, Weibo discussions, and web search. Covers customer sentiment by location, local competition analysis, neighborhood trends, and location-specific brand perception.
日本語の概要は準備中です。原文の説明を表示しています。
Research any topic across China's major social platforms — Weibo, Douyin, Xiaohongshu, Bilibili, and Zhihu — simultaneously. Aggregates discussion volume, sentiment, key opinion leaders, and platform-specific trends for comprehensive China market intelligence.
日本語の概要は準備中です。原文の説明を表示しています。
Convert between currencies with real-time exchange rates. Supports 150+ currencies including crypto, with historical rate lookup. Useful for international pricing, financial reporting, and cross-border commerce research.
日本語の概要は準備中です。原文の説明を表示しています。
Rapidly assess crisis situations by monitoring Twitter, Reddit, news, and Chinese social platforms simultaneously. Detects escalation velocity, identifies key narratives, tracks official responses, and measures public sentiment shifts during critical events.
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Monitor brand mentions, sentiment, and reputation across Twitter, Reddit, news, and social platforms through SandBase. Use when asked for brand monitoring, reputation tracking, social listening, PR coverage analysis, or competitive brand intelligence.
日本語の概要は準備中です。原文の説明を表示しています。
Track real-time events, announcements, and breaking developments across Twitter, Reddit, news outlets, and web search. Monitors event progression, public reaction, key moments, and aftermath coverage for crisis response and opportunity detection.
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Analyze customer reviews for local businesses on Google Maps. Covers review extraction, sentiment patterns, rating distribution, common complaints, and competitor review comparison for local business intelligence and reputation management.
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Search real live music, theater, dance, comedy, film, art, sports, festivals, markets, food and drink, nightlife, classes, talks and lectures, books and literary events, tours, outdoors and nature programs, family and kids activities, social and dating nights, networking and business events, wellness classes, religion and spirituality services, civic meetings, charity and volunteering in New York City — with dates, times, prices, booking links and images. Use this whenever someone asks what to do, where to go, what is on, or where to take people in New York, for any date or none, even if they do not name SyncSo. Live catalogue, updated continuously.
日本語の概要は準備中です。原文の説明を表示しています。